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Zolpistar (Zolpidem)

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Zolpistar is the best sleeping tablets for insomnia patients. Zolpistar is a sedative, also called a hypnotic. It affects chemicals in your brain that may become unbalanced and cause insomnia. Zolpistar is used to treat insomnia.The immediate-release forms of Zolpistar are Ambien, Intermezzo, Edluar, and Zolpimist, which are used to help you fall asleep. The extended-release form of Zolpistar is Ambien CR, which has a first layer that dissolves quickly to help you fall asleep, and a second layer that dissolves slowly to help you stay asleep. Ambien, Edluar, and Zolpimist are used to help you fall asleep when you first go to bed. Intermezzo, is used to help you fall back to sleep if you wake up in the middle of the night and then have trouble sleeping.

Other names for this medication:
Ambiz, Ambulax, Azold, Getrest, Insom, Inzofresh, Isodem, Lipidem, Lopitas, Lypin, Nidra, Nitrest, Olpid, Sobrium, Stilnoct, Syzol, Zleep, Zodem, Zolax, Zolcent, Zoldem, Zolfresh, Zolojet, Zolpiapt, Zolpid, Zolpidem, Zolpimist, Zolpistar, Zolpitrac, Zolsoma, Zoltar, Zolway, Zomnia

Similar Products:
Avana, Danocrine, Zofran, Provigil, Eulexin, Bactrim, Sayobend, Nictram, Glyzip, Calcigard, Nefelid,

Also known as: Zolpidem


Zolpidem is used to treat insomnia (trouble sleeping). It belongs to the group of medicines called central nervous system (CNS) depressants, which slows down the nervous system. Zolpidem will help you get to sleep faster and sleep throughout the night. In most cases, sleep medicines should only be used for short periods of time, such as 1 or 2 days, and for no longer than 1 or 2 weeks.

This medicine is available only with your doctor's prescription.


Use the lowest effective dose for the patient. The recommended initial dose is 5 mg for women and either 5 or 10 mg for men, taken only once per night immediately before bedtime with at least 7–8 hours remaining before the planned time of awakening. If the 5 mg dose is not effective, the dose can be increased to 10 mg. In some patients, the higher morning blood levels following use of the 10 mg dose increase the risk of next day impairment of driving and other activities that require full alertness.

The total dose of Zolpistar should not exceed 10 mg once daily immediately before bedtime. Zolpistar should be taken as a single dose and should not be readministered during the same night.

The recommended initial doses for women and men are different because zolpidem clearance is lower in women.


In postmarketing experience of overdose with Zolpistar tartrate alone, or in combination with CNS-depressant agents, impairment of consciousness ranging from somnolence to coma, cardiovascular and/or respiratory compromise, and fatal outcomes have been reported.

General symptomatic and supportive measures should be used along with immediate gastric lavage where appropriate. Intravenous fluids should be administered as needed. Zolpistar's sedative hypnotic effect was shown to be reduced by flumazenil and therefore may be useful; however, flumazenil administration may contribute to the appearance of neurological symptoms (convulsions). As in all cases of drug overdose, respiration, pulse, blood pressure, and other appropriate signs should be monitored and general supportive measures employed. Hypotension and CNS depression should be monitored and treated by appropriate medical intervention. Sedating drugs should be withheld following Zolpistar overdosage, even if excitation occurs. The value of dialysis in the treatment of overdosage has not been determined, although hemodialysis studies in patients with renal failure receiving therapeutic doses have demonstrated that Zolpistar is not dialyzable.

As with the management of all overdosage, the possibility of multiple drug ingestion should be considered. The physician may wish to consider contacting a poison control center for up-to-date information on the management of hypnotic drug product overdosage.


Store at controlled room temperature 20–25 degrees C (68–77 degrees F).

Do not flush medications down the toilet or pour them into a drain unless instructed to do so. Properly discard this product when it is expired or no longer needed. Consult your pharmacist or local waste disposal company.

Side effects

The most common side effects associated with Zolpistar are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.


In deciding to use a medicine, the risks of taking the medicine must be weighed against the good it will do. This is a decision you and your doctor will make. For this medicine, the following should be considered:

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Neuroprotective effect of regional carnitine on spinal cord ischemia--reperfusion injury. No long-range contacts between remote fragments of the chain were detected with paramagnetic relaxation enhancement experiments. Histologic examination of the ED 11-exposed embryo showed the presence of abnormal notochord that was stretched, split, or tethered to the foregut. DC-SIGN, a novel C-type lectin that is expressed in DCs, has recently been shown to bind R5 HIV type 1 (HIV-1) strains and a laboratory-adapted X4 strain. These features were quantitatively lower than the values reported in offspring of white Caucasian and African-American patients. Our results showed that the integration of radiographs and photographs is an objective and reliable method to obtain NHP in lateral cephalograms. Spontaneous changes in mitochondrial membrane potential in cultured neurons. High-speed separation system of randomly suspended single living cells by laser trap and dielectrophoresis. Occupational exposure to pesticides and congenital malformations: a review of mechanisms, methods, and results.

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The objective of this study was to describe determinants of cat and dog ownership in European families with and without allergies. The meta-analysis shows that the use of tranexamic acid for patients undergoing total knee arthroplasty is effective and safe for the reduction of blood loss. Advances in functional neuromuscular stimulation (FNS) have increased the need for nerve cuff designs that can control multiple motor functions through selective stimulation of selected populations of axons. Previous studies have demonstrated a high rate of loss of heterozygosity (LOH) within a critical region of chromosome 1p in UPSC, suggesting the presence of a putative tumor suppressor gene important in the development of UPSC. Free-breathing multiphase whole-heart coronary MR angiography using image-based navigators and three-dimensional cones imaging. Most bone ultrasound devices are designed for through-transmission measurements of the calcaneus. Anticonvulsant activity, organotypic hippocampal neuroprotection assay and in-silico sodium channel blocking potential of 2-amino-6-nitrobenzothiazole derived semicarbazones.

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While E1 and E2 enzymes have only been minimally linked to cancer development, burgeoning amounts of evidence have implicated loss or gain of E3 function as a key factor in cancer initiation and progression. Patients with syncope underwent head-up tilt testing at 60 degrees and 80 degrees followed by edrophonium or isoproterenol challenge when indicated. To determine the transmission rate of human papillomavirus (HPV) in newborn infants of HPV-positive women and to assess the relationship between perinatal HPV transmission and mode of delivery. This study sought to evaluate the relation, if any, between clinical and angiographic findings in patients with unstable angina and monocyte and neutrophil CD11b/CD18 receptor density. Critical review of mercury fates and contamination in the Arctic tundra ecosystem.

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Keratinocyte cultures were far more sensitive to UVB radiation than reconstituted epidermis, in terms of both cytotoxicity and cytokine release. To observe the effects of attenuated measles virus on hepatitis B virus replication inside and outside the body. Mutagenic properties of copper iodide and copper sulfate were not detected. Hepatectomy for selected elderly patients with HCC possibly have a better curative effect compared with younger patients. Estrogens stimulate hippocampal synaptogenesis, enhance cholinergic neurotransmission, possess anti-oxidative and anti-amiloidogenic properties, dilate cerebral vessels and have platelet anti-aggregating activity. However, the process of reactivation is not entirely understood and requires further investigations. To assess the handicapping effect of dizziness related to posture and balance, the Dizziness Handicap Inventory (DHI) and Computerized Dynamic Posturography (CDP) were used to assess 101 consecutive patients referred for neurotologic evaluation of dizziness. As opposed to rat plasma, human plasma may be an interesting in vitro model to study the metabolism of a drug extensively metabolized by SSAO such as tresperimus. After recent UK policy developments, considerable attention has been focused upon how clinical specialties measure and report on the quality of care delivered to patients.

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Clinical-tomographic correlation in patients with neurologic deficits of the brain due to diabetes mellitus. The drainage fluid contained pus, similar to the fluid from the retroperitoneal drainage. Validation of reference genes for normalization of real-time quantitative RT-PCR data in traumatic brain injury. The use of adjunctive agents reducing the surface tension associated with oxidant and chelating agents improved the antimicrobial activity of irrigating solutions and intratubular decontamination against Enterococcus faecalis, possibly due to better removal of the smear layer and deeper penetration into dentinal tubules. The endonasal route may be feasible for the resection of anterior cranial base tumors that abut the paranasal sinuses. Clinical multicenter evaluation of a new FXa-based Antithrombin assay. CI and the level of premorbid reviews on zantac 360 disability influenced the risk of death. Chief Nursing Officer Survey: BSN and Higher Degree Initiatives in North Carolina. The clinical and diagnostic aspects of retained surgical gauze have been discussed and the need for radio-opaque markers in them have been emphasized.

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The discovery of these novel enzymatic activities that are essentially involved in MLL fusion protein function presents potential new targets for a rational drug development. The effects of antagonism towards the androgenic receptor were studied. The modulation of the soleus H-reflex in response to tonic mechanical loading applied to the plantar aspect of the foot sole was periactin reviews examined in nine normal subjects and five patients with a clinically defined complete spinal cord injury (SCI). To estimate the national incidence of, operation-level risk factors for, and annual economic impact of colic among horses in the United States during 1998 and 1999. The semi-logarithmic plots of apparent degradation rate constant against the reciprocal of illuminance showed a good linear relationship in the Arrhenius-type fashion, and the photostability under ordinary illumination conditions could be predicted from the data obtained under the accelerated illumination conditions. Effect of ADAM28 on carcinoma cell metastasis by cleavage of von Willebrand factor.

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Greenhouse gas and alcohol emissions from feedlot steers and calves. Protein samples were extracted from two biological replicates and subjected to two dimensional gel electrophoresis analysis and mass spectrometry. Diagnosis and therapy are overwhelmingly the responsibility of the family physician. The split-ubiquitin yeast two-hybrid system was used to characterize molecular interactions of membrane-bound, full-length murine SYP. Pharmacologic agents in ARDS is important due to the multifactorial pathophysiologic and pharmacodynamic processes that are part of the disease. As to the mode of action, torilin downregulated alpha-MSH-induced protein levels of tyrosinase without directly inhibiting catalytic activity of the enzyme.

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