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Rockbon (Calcitriol)
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Rockbon

Rockbon is a form of vitamin D3. Vitamin D helps your body absorb calcium from the stomach. Rockbon is used to treat hyperparathyroidism (overactive parathyroid glands) and metabolic bone disease in people who have chronic kidney failure and are not receiving dialysis.

Other names for this medication:
Admax, Alfacal, Alfacalcirol, Alfarich, Arachitol, Arcium, Aristrol, Biocitral, Calbec, Calbory, Calbovic, Calcibest, Calcicare, Calcigra, Calcirol, Calcit, Caldikind, Calfa, Calgel, Calosto, Calotec, Calsure, Caltop, Carcal, Citroj, Denscal, Duracal, Fovit, Koncal, Minroset, Netxod, Osteobel, Politrol, Primacal, Rical, Riecal, Ritoca, Rockbon, Roical, Romical, Septriol, Solbiocal, Sorvate, Statbone, Tobalt, Vitalpha

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Ceftin, Arava, Nizoral, Minocin, Zetia, Vasotec, Noroxin, Albenza, Effexor, Sporanox, Metomac, Diazecalm, Nifcal, Certen, Trimontemac, Lorzin, Cyperton, Cetcold, Devot,

Also known as: Calcitriol

Description

Generic Rockbon is a synthetic vitamin D analog which is active in the regulation of the absorption of calcium from the gastrointestinal tract and its utilization in the body. The two known sites of action of Generic Rockbon are intestine and bone. Generic Rockbon receptor-binding protein appears to exist in the mucosa of human intestine. Additional evidence suggests that Generic Rockbon may also act on the kidney and the parathyroid glands. Generic Rockbon is the most active known form of vitamin D3 in stimulating intestinal calcium transport. In acutely uremic rats Generic Rockbon has been shown to stimulate intestinal calcium absorption. The kidneys of uremic patients cannot adequately synthesize Generic Rockbon, the active hormone formed from precursor vitamin D. Resultant hypocalcemia and secondary hyperparathyroidism are a major cause of the metabolic bone disease of renal failure. However, other bone-toxic substances which accumulate in uremia (eg, aluminum) may also contribute. The beneficial effect of Generic Rockbon in renal osteodystrophy appears to result from correction of hypocalcemia and secondary hyperparathyroidism. It is uncertain whether Generic Rockbon produces other independent beneficial effects. Rockbon is also known as Calcitriol. Generic Rockbon treatment is not associated with an accelerated rate of renal function deterioration. No radiographic evidence of extraskeletal calcification has been found in predialysis patients following treatment. The duration of pharmacologic activity of a single dose of calcitriol is about 3 to 5 days. Generic name of Generic Rockbon is Calcitriol. Brand name of Generic Rockbon is Rockbon.

Dosage

This section provides information on the proper use of a number of products that contain vitamin d and related compounds. It may not be specific to Rockbon. Please read with care.

For use as a dietary supplement:

Do not take more than the recommended daily amount. Vitamin D is stored in the body, and taking too much over a period of time can cause poisoning and even death.

If you have any questions about this, check with your health care professional.

For individuals taking the oral liquid form of this dietary supplement:

This preparation should be taken by mouth even though it comes in a dropper bottle. This dietary supplement may be dropped directly into the mouth or mixed with cereal, fruit juice, or other food.

While you are taking alfacalcidol, calcifediol, calcitriol, dihydrotachysterol, doxercalciferol or paricalcitol , your health care professional may want you to follow a special diet or take a calcium supplement. Be sure to follow instructions carefully. If you are already taking a calcium supplement or any medicine containing calcium, make sure your health care professional knows.

The dose medicines in this class will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of these medicines. If your dose is different, do not change it unless your doctor tells you to do so.

The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.

For alfacalcidol To treat bone disease in kidney patients undergoing kidney dialysis: For oral dosage form (capsules): Adults and teenagers—At first, 1 microgram (mcg) a day. Your doctor may change your dose if needed. However, most people will take not more than 3 mcg a day. For oral dosage form (drops): Adults and teenagers—At first, 1 microgram (mcg) a day. Your doctor may change your dose if needed. However, most people will take not more than 3 mcg a day. For oral dosage form (solution): Adults and teenagers—At first, 1 mcg a day. Your doctor may change your dose if needed. However, most people will take not more than 3 mcg a day. For parenteral dosage form (injection): Adults and teenagers—At first, 1 mcg a day. Your doctor may change your dose if needed. However, most people will take not more than 12 mcg a week. To treat diseases in which calcium is not used properly by the body: For oral dosage form (capsules): Adults and teenagers—At first, 0.25 microgram (mcg) a day. Your doctor may change your dose if needed. However, most people will take not more than 1 mcg a day. For oral dosage form (drops): Adults and teenagers—At first, 0.25 microgram (mcg) a day. Your doctor may change your dose if needed. However, most people will take not more than 1 mcg a day. For oral dosage form (solution): Adults and teenagers—At first, 0.25 mcg a day. Your doctor may change your dose if needed. However, most people will take not more than 1 mcg a day.

For calcifediol To treat diseases in which calcium is not used properly by the body or to treat bone disease in kidney patients undergoing kidney dialysis: For oral dosage form (capsules): Adults, teenagers, and children over 10 years of age—At first, 300 to 350 micrograms (mcg) a week, taken in divided doses either once a day or every other day. Your doctor may change your dose if needed. Children 2 to 10 years of age—50 mcg a day. Children up to 2 years of age—20 to 50 mcg a day. To treat diseases in which calcium is not used properly by the body or to treat bone disease in kidney patients undergoing kidney dialysis: For oral dosage forms (capsules and solution): Adults, teenagers, and children—At first, 0.25 micrograms (mcg) a day. Your doctor may change your dose if needed. For parenteral dosage forms (injection): Adults and teenagers—At first, 0.5 mcg injected into a vein three times a week. Your doctor may change your dose if needed. Children—Use and dose must be determined by your doctor.

For dihydrotachysterol To treat diseases in which calcium is not used properly by the body: For oral dosage forms (capsules, solution, or tablets): Adults and teenagers—At first, 100 micrograms (mcg) to 2.5 milligrams (mg) a day. Your doctor may change your dose if needed. Children—At first, 1 to 5 mg a day. Your doctor may change your dose if needed.

For doxercalciferol To treat an overactive parathyroid gland in patients with kidney failure: For oral dosage form (capsules): Adults—10 micrograms (mcg) three times weekly at dialysis. The doctor may change your dose if needed. Children—Use and dose must be determined by your doctor.

For ergocalciferol The amount of vitamin D to meet normal daily recommended intakes will be different for different individuals. The following information includes only the average amounts of vitamin D. To prevent deficiency, the amount taken by mouth is based on normal daily recommended intakes: For oral dosage form (capsules): For the U.S. Adults and teenagers—5 to 10 micrograms (mcg) (200 to 400 Units) per day. Pregnant and breast-feeding females—10 mcg (400 Units) per day. Children 4 to 10 years of age—10 mcg (400 Units) per day. Children birth to 3 years of age—7.5 to 10 mcg (300 to 400 Units) per day. For Canada Adults and teenagers—2.5 to 5 mcg (100 to 200 Units) per day. Pregnant and breast-feeding females—5 to 7.5 mcg (200 to 300 Units) per day. Children 7 to 10 years of age—2.5 to 5 mcg (100 to 200 Units) per day. Children 4 to 6 years of age—5 mcg (200 Units) per day. Children birth to 3 years of age—5 to 10 mcg (200 to 400 Units) per day. To treat deficiency: Adults, teenagers, and children—Treatment dose is determined by prescriber for each individual based on severity of deficiency. To treat diseases in which calcium and phosphate are not used properly by the body: Adults and teenagers—At first, 1000 to 500,000 Units a day. The doctor may change your dose if needed. Children—At first, 1000 to 200,000 Units a day. The doctor may change your dose if needed.

For paricalcitol To treat an overactive parathyroid gland in patients with kidney failure: For oral dosage form (capsules): Adults—1 to 2 micrograms (mcg) one time per day or 2 to 4 mcg three times a week (not more often than every other day). The doctor may change your dose if needed. Children—Use and dose must be determined by your doctor. For parenteral dosage form (injection): Adults—0.04 to 0.1 micrograms (mcg) per kg no more than every other day during dialysis. The doctor may change your dose if needed. Children—Use and dose must be determined by your doctor.

Overdose

If you overdose Generic Rockbon and you don't feel good you should visit your doctor or health care provider immediately.

Storage

Store at room temperature between 15 and 30 degrees C (59 and 86 degrees F) away from moisture, light and heat. Keep container tightly closed. Throw away any unused medicine after the expiration date. Keep out of the reach of children.

Side effects

The most common side effects associated with Rockbon are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.

Contraindications

It is especially important that you receive the right amounts of vitamins so that your baby will also get the vitamins needed to grow properly. Infants who are totally breast-fed and have little exposure to the sun may require vitamin D supplementation. However, taking large amounts of a dietary supplement while breast-feeding may be harmful to the mother and/or baby and should be avoided.

Only small amounts of alfacalcidol, calcifediol, calcitriol, or dihydrotachysterol pass into breast milk and these amounts have not been reported to cause problems in nursing babies.

It is not known whether doxercalciferol or paricalcitol passes into breast milk. Be sure you have discussed the risks and benefits of the supplement with your doctor.

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Guidelines of the Indian Association of Cardiovascular and Thoracic Anaesthesiologists and Indian College of Cardiac Anaesthesia for perioperative transesophageal echocardiography fellowship examination. Wearable technologies - future challenges for implementation in healthcare services. Immunized animals were not affected by iron treatment during challenge. This work has implications for mosquito surveillance and vector control activities not only in California but also in other regions where the distribution of this invasive mosquito is expanding. The melanocortin 4 receptor (MC4R) is a G protein-coupled receptor (GPCR) that is expressed in several brain nuclei playing a crucial role in the regulation of energy balance controlling the homeostasis of the organism. Moreover, this study aimed to determine whether the prescriptions comply with the recommended guidelines and whether clinical audit can alter the prescribing practices of dentists leading to better use of antibiotics in the dental service. A total of 55 men a mean of 73 years old with outflow obstruction, including 9 who presented in urinary retention, underwent endoscopic laser ablation of the prostate and temporary stenting. These techniques also proved helpful to surgeons in achieving cure with conservative bone excision.

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Effect of Exericse and Nutrition upon Lifestyle-Related Disease and Cognitive Function. It was of interest to determine if any of the other protein components in the Achlya Hsp90-heterocomplexes would be homologous to those found in the steroid receptor-Hsp90-heterocomplexes of vertebrates. We then tested possible age and gender moderation of factor stability, finding that the stability for all factors, except fear, significantly differed across demographic sub-groups. Contractile and electric activity of the extrahepatic biliary tract and duodenum. The consequences of hyperosmotic and chill stress seem to differ, either causing dehydration of the cytoplasm or leading to impairment of cellular functions due to low temperature.

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On transferable resistance of strains of Enterobacteriaceae isolated in Rumania. Adult rat retinal glia in vitro: effects of in vivo crush-activation on glia proliferation and permissiveness for regenerating retinal ganglion cell axons. This is a meta-analysis comparing biomechanical outcomes to determine whether an isolated posterior cruciate ligament (PCL) reconstruction can restore normal knee kinematics in a combined PCL/posterolateral complex (PLC) injury and whether double-bundle (DB) PCL reconstruction is superior in controlling posterior and rotational laxity compared with single-bundle (SB) PCL reconstruction in a PCL/PLC-deficient knee. Importantly, in all animals studied, loss and gain of Engrailed function severely disrupted the pathfinding of the spinal motor axons, suggesting that Engrailed plays an evolutionarily conserved role in the separate innervation of vertebrate epaxial-hypaxial muscle. In order to identify new breast cancer vulnerabilities and improve therapeutic chances for patients, we performed in vivo and in vitro shRNA screens in a human breast cancer cell model (MCF10DCIS.com cell line) using epigenetic libraries. These findings suggest a novel postsynaptic action of SS-14 leading to depression of synaptic responses mediated by GABAA and GABAB receptors. In a statistically powerful test of this question, indirect and direct tests of memory were administered to 584 adults from three age groups (19-36 years, 55-69 years, 70-86 years). The results show that the method can be used in antibiotic resistance early warning systems. Transplantation of ES cells could be a potential treatment in supporting life during acute liver insufficiency and could be a bridge to orthotopic liver transplantation. The SAMs are formed on graphene via noncovalent bonds without altering the structure of the graphene.

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Contrast-Enhanced Ultrasound Angiogenesis Imaging by Mutual Information Analysis for Prostate Cancer Localization. Emergence of drug-resistant influenza virus: population dynamical considerations. One known central effect of HA is the stimulation of ACTH and corticosteroid release. A total of 212,098 new cases of gastrointestinal cancer were identified during the study period (129,233 males and 82,865 females), among whom 18,146 had esophageal cancer, 71,011 gastric cancer, 55,864 colorectal cancer, 42,751 liver cancer, 9,382 gallbladder cancer and 14,944 had pancreatic cancer. Antiviral effects of xanthate D609 on the human respiratory syncytial virus growth cycle. Our data indicate that treatment of MC can modulate the expression of MMPs and TIMPs in vitro and in vivo in SHR. Results indicate potentially important age differences when examining the impact of functional disability on depressive symptoms in this sample. In vivo, STI 571 treatment reduced the number of glomerular mesangial cells positive for both phosphorylated STAT3 and proliferating cell nuclear antigen. Additionally, we identified six factor binding footprints in the upstream region of this promoter (FP 1-FP 6), two of which (FP 2 and FP 4) we showed to be C/EBP binding sites. Comparison of linear and non-linear models for predicting energy expenditure from raw accelerometer data.

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There is a need to examine the experimental data ranging from single-fiber experiments to the muscle function in human movement in order to understand the muscle-tendon function in vivo fully. New species of the miniature genus Gelanoglanis (Siluriformes: Auchenipteridae) from the Tocantins River basin (Brazil) and osteological description of G. This was a substudy of the Normal echOcardiogRaphic Measurements in KoreAn popuLation (NORMAL) study. The results provide new insights on the mechanism by which high avidity anticapsular antibodies elicited by polysaccharide-conjugate vaccines affect meningococcal colonization. Acute neurotoxicity in children with B-precursor acute lymphoid leukemia: an association with intermediate-dose intravenous methotrexate and intrathecal triple therapy--a Pediatric Oncology Group study. Between May 1990 and July 2005, 22 female patients were diagnosed with acute haemorrhage and/or rupture of lesions highly suspicious of HCA. Before anchoring the trocar, a piece of Tegaderm polyurethrane adhesive (3M Healthcare, St. Mesenteric arteriovenous shunt associated with thrombosis of the portal venous system: case report. The neurohumoral regulation and energy support of the myocardium in patients with heart rhythm disorders.

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Early Life Residence, Fish Consumption, and Risk of Breast Cancer. The progestin contraceptives, megestrol acetate, melengesterol acetate, medroxyprogesterone acetate, and levonorgestrol (administered orally, in implants, or as depot injections), are effective in preventing pregnancy. A PubMed search for studies describing fractionation during human atrial electrophysiologic measurements resulted in 348 articles that were screened for new definitions of fractionation. Many ear amputations result from avulsion and thus have damaged and often diminutive vessels with a paucity of veins. The mass, stiffness and piezoelectric stiffness matrices of the modelled segment can be extracted using a conventional finite element code. Successful integration of such strategies will be dependent on effective governance mechanisms, effective partnerships and coalition building and accurate evaluation systems at national, regional and global levels. However, effects varied according to several study features and were smallest in the better controlled studies. The modified frozen elephant adalat 10 mg prezzo trunk repair is particularly well suited for patients with chronic aortic dissection who often require multiple operations to address their extensive disease. n., the etiologic agent of a disease of the California sea mussel, Mytilus californianus Conrad. The time course for accumulation of the various subunits was compared in seedlings that received a red light pulse 4 h prior to transfer to continuous white light and parallel controls that did not receive a red light pulse.

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Efficacy of crocin and safranal as protective agents against genotoxic stress induced by gamma radiation, urethane and procarbazine in mice. There is also some evidence that functional capacities are restored and that these changes lead to more favorable health outcomes. The models included the fixed effects of contemporary group and generation. They were asked if and how they taught EBM on returning to their institutions, if they felt competent to critically appraise an article, if their skill in searching PubMed improved, and if they collaborated with others in teaching EBM. Clinicians should be aware of this at-risk population when screening for distress in cancer survivors. Adrenal hemangioma is an extremely rare benign and non-functioning neoplasm of the adrenal gland. In this context of high prevalence of opportunistic infections, a lower exposure to cotrimoxazole in children than adults was noted. Inside the blobs, scattering experiments indicate the polymer covered and stacked clay platelets oriented in the plane of the film. Piwil2 modulates the invasion and metastasis of prostate cancer by regulating the expression of matrix metalloproteinase-9 and epithelial-mesenchymal transitions. The gates are heralded by the electron spins associated with the diamond NV centers.

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The safety culture was measured with Hospital Survey on Patient Safety Culture. Practice characteristics recorded included geographic location, academic affiliation, number of new cases, number of medical oncologists, and rounds of participation in Quality Oncology Practice Initiative. At present, more than 300 types of complementary and/or alternative medicine (CAM) treatments are known that offer different therapeutic objectives. Therefore, developing an automatic ROI/RONI selection is a challenge task. We were able to show that an lipitor 20 mg tabs integrative concept including surgery is a good additional option for the treatment of severe cases of lymphedema in appropriate candidates. Decrease in tyrosine hydroxylase, but not aromatic L-amino acid decarboxylase, messenger RNA in rat olfactory bulb following neonatal, unilateral odor deprivation. This was a plausible mechanism for the transient hypointense lesion on DWI with increased apparent diffusion coefficient value.

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In serial generalized-ensemble simulations, the sampling of a collective coordinate of a system is enhanced through non-Boltzmann weighting schemes. Zinc finger protein gene complexes on mouse chromosomes 8 and 11. Study of protein-bound serum hexose and urinary glycoproteins in acute appendicitis. As an alternative we propose a statistically rigorous approach to infer nest type based on large datasets of eggshell porosity and egg mass compiled for over 120 extant archosaur species and 29 archosaur extinct taxa/ootaxa. The results indicate that BRCA1 and p53 may coordinately regulate gene expression in their role as tumor suppressors.

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The IADF filter is the optimal method and it is capable of strong speckle suppression with less computational complexity. Prostate cancer (PCa) is one of the most widespread malignancies in the world. Effects of tai chi qigong on psychosocial well-being among hidden elderly, using elderly neighborhood volunteer approach: a pilot randomized controlled trial. Results indicate that age was significantly associated with performance on time, accuracy, reasoning subskills, and rationale criteria, whereas the level of education was significantly associated with accuracy and rationale. We fit the model to the longitudinal data in a cohort study in China to reconstruct the treatment benefit index, and we describe the dependence of individual life expectancy on key ART treatment specifics including the timing of ART initiation, timing of emergence of drug resistant virus variants and ART adherence. As early as 1985, seizure reduction in children could be demonstrated in a few cases with photosensitive, self-induced epilepsy. Even for molecules of the same family, significant differences in the excitation processes have been noted. The ellipticity values of the six peptides at 222 nm how much does ventolin cost in australia range from -31,600 to -7400 deg cm2 dmol-1 in the order listed.

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