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Resta (Alprazolam)

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Resta is a potent, short-acting benzodiazepine anxiolytic—a minor tranquilizer. It is commonly used for the treatment of anxiety disorders, especially of panic disorder. It's also used in the treatment of generalized anxiety disorder (GAD) or social anxiety disorder. It was the 12th most prescribed medicine in the United States in 2010. Resta, like other benzodiazepines, binds to specific sites on the GABAA receptor. It possesses anxiolytic, sedative, hypnotic, skeletal muscle relaxant, anticonvulsant, amnestic, and antidepressant properties. Resta is available for oral administration as compressed tablets (CT) and extended-release capsules (XR).

Other names for this medication:
Albiz, Allam, Alpkair, Alpose, Alpram, Alprasert, Alprastan, Alprocalm, Altin, Alzex, Alzoax, Anxicalm, Anxico, Anxit, Axizox, Axnil, Azolam, Dazolam, Diprex, Emcalm, Enxolam, Ezoprax, Kaprolam, Luzarn, Mcalm, Mentolift, Morecalm, Notens, Oclam, Omelam, Onapract, Paxor, Proprazolam, Samitol, Sanprazole, Somaspas, Somnirest, Sowel, Tancalm, Tensfree, Zamitol, Zeprax, Zodia, Zolar, Zoldac, Zopic

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Anafranil, Coreg, Addyi, Ovral, Coumadin, Singulair, Allegra, Nexium, Cleocin, Taremis, Nexium, Nilol, Theoder, Biselect, Zepox, Campin, Budenase, Cozil,

Also known as: Alprazolam


Alprazolam is used to relieve symptoms of anxiety, including anxiety caused by depression. It is also used to treat panic disorder in some patients.

Alprazolam is a benzodiazepine. Benzodiazepines belong to the group of medicines called central nervous system (CNS) depressants, which are medicines that slow down the nervous system.

This medicine is available only with your doctor's prescription.


This section provides information on the proper use of a number of products that contain alprazolam. It may not be specific to Resta. Please read with care.

Take this medicine only as directed by your doctor. Do not take more of it, do not take it more often, and do not take it for a longer time than your doctor ordered. If too much of this medicine is used for a long time, it may become habit-forming (causing mental or physical dependence) or cause an overdose.

This medicine should come with a Medication Guide. Read and follow the instructions carefully. Ask your doctor if you have any questions.

Swallow the extended-release tablet or tablet whole with a full glass of water. Do not break, crush, or chew it.

If you are using the orally disintegrating tablet, make sure your hands are dry before you handle the tablet. Do not remove the tablets from the bottle until you are ready to take it. Place the tablet immediately on the top of your tongue. It should melt quickly and be swallowed with saliva.

If you are using the oral liquid, measure the dose with a marked measuring spoon, oral syringe, or medicine cup.

Do not eat grapefruit or drink grapefruit juice while you are using this medicine.

The dose of this medicine will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of this medicine. If your dose is different, do not change it unless your doctor tells you to do so.

The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.

For anxiety: For oral dosage forms (solution, tablets, or orally disintegrating tablets): Adults—At first, 0.25 to 0.5 milligram (mg) 3 times a day. Your doctor may increase your dose as needed. However, the dose is usually not more than 4 mg per day. Older adults—At first, 0.25 mg 2 or 3 times a day. Your doctor may increase your dose as needed. Children—Use and dose must be determined by your doctor. For panic disorder: For oral dosage form (extended-release tablets): Adults—At first, 0.5 to 1 milligram (mg) taken in the morning once a day. Your doctor may increase your dose as needed. However, the dose is usually not more than 10 mg per day. Older adults—At first, 0.5 mg taken in the morning once a day. Your doctor may increase your dose as needed. Children—Use and dose must be determined by your doctor. For oral dosage forms (solution, tablets, or orally disintegrating tablets): Adults—At first, 0.5 milligram (mg) 3 times a day. Your doctor may increase your dose as needed. However, the dose is usually not more than 10 mg per day. Older adults—At first, 0.25 mg 2 or 3 times a day. Your doctor may increase your dose as needed. Children—Use and dose must be determined by your doctor.


If you have been prescribed Resta for medical reasons, the best way to avoid a Resta overdose is to adhere to prescribed orders—closely monitor your dose and the time at which you take your medication. Track your Resta consumption in a notebook or on your phone. If you notice that you are taking a higher dose of the drug, taking the drug more often, or you want to consume more of the drug, talk with your doctor immediately.


Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing.

Keep out of the reach of children.

Do not keep outdated medicine or medicine no longer needed.

Ask your healthcare professional how you should dispose of any medicine you do not use.

It is very important to protect the orally disintegrating tablets from moisture. Remove and throw away any cotton packaging from the medicine bottle when you first use the medicine.

Detailed Resta XR dosage information

Side effects

The most common side effects associated with Resta are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.


Drug interactions may change how your medications work or increase your risk for serious side effects. This document does not contain all possible drug interactions. Keep a list of all the products you use (including prescription/nonprescription drugs and herbal products) and share it with your doctor and pharmacist. Do not start, stop, or change the dosage of any medicines without your doctor's approval.Some products that may interact with this drug include: kava, sodium oxybate.Other medications can affect the removal of Resta from your body, which may affect how Resta works. Examples include azole antifungals (such as itraconazole, ketoconazole), cimetidine, certain anti-depressants (such as fluoxetine, fluvoxamine, nefazodone), drugs to treat HIV (delavirdine, protease inhibitors such as indinavir), macrolide antibiotics (such as erythromycin), rifamycins (such as rifabutin), St. John's wort, drugs used to treat seizures (such as carbamazepine, phenytoin), among others.Tell your doctor or pharmacist if you also take drugs that cause drowsiness such as: certain antihistamines (such as diphenhydramine), medicine for sleep or anxiety (such as diazepam, zolpidem), muscle relaxants, narcotic pain relievers (such as codeine), psychiatric medicines (such as chlorpromazine, risperidone, amitriptyline, trazodone).Check the labels on all your medicines (such as cough-and-cold products) because they may contain ingredients which cause drowsiness. Ask your pharmacist about the safe use of those products.Cigarette smoking decreases blood levels of this medication. Tell your doctor if you smoke or if you have recently stopped smoking.

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Inhibition of Human Drug Transporter Activities by the Pyrethroid Pesticides Allethrin and Tetramethrin. Ectopic epididymal expression of guinea pig intestinal phospholipase B. The non-linear oscillations are observed by the surfactant transfer from a point-like source situated in the bulk of liquid, by the transfer of two ionic solutes through a liquid interface in two opposite directions, and by the transfer of ionic solutes through a liquid membrane. Colon perforation due to diverticulitis is a life-threatening complication in the postoperative course of kidney transplantation. Studies of women with gynecological cancer at any point on the continuum of care from pre-diagnosis to survivorship or end of life, including those with a recurrence of the disease, were included, with no limit to the duration of care received for inclusion in the review. Hence, the aim of this work was to contribute to the fight against helminths of medical and veterinary importance in general, and also to clear the environment of their free living stages. In this article, evidence that cytokines and glucocorticoids play an important role in the regulation of hepatic and muscle protein metabolism during sepsis is presented.

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An attempt at a modern elementary description of orientation activities. We sent letters to 931 registered dentists in Biscay, with an explanation of the study objectives, description of a case of lower third molar impaction, including a panoramic radiograph, and a questionnaire. The samples were tested against anaerobic strains commonly found in oro-dental infections. This paper explores the relevant pathways in which an integrated biomethane industry could potentially materialise and identifies and discusses the latest biotechnological advances in the production of renewable gas. Here, we focus on recent advances in mechanisms of TET-TDG mediated demethylation and cellular strategies that avoid genomic instability. Clinical study and immunological observation on potenlini treatment of epidemic hemorrhage fever.

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Compared with classic AAM methods, the segmentation performance is substantially improved with the proposed scheme. Toxicities from the chemotherapy and irradiation preparative regimen for bone marrow transplantation include nausea, emesis, and oral pain. Experimental Design and Data Analysis Issues Contribute to Inconsistent Results of C-Bouton Changes in Amyotrophic Lateral Sclerosis. Ankylosing spondylitis does not increase the risk of neurogenic heterotopic ossification in patients with a spinal cord injury: a retrospective cohort study. This missense mutation, which replaces Ala with Thr, is frequent among FNDI patients and is thought to reduce the efficiency of cleavage by signal peptidases.

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Bioprinting is an emerging technology that allows the assembling of both living and non-living biological materials into an ideal complex layout for further tissue maturation. Both pharmacologic and endoscopic techniques have been developed to achieve hemostasis, with varying degrees of success. The reduction in voluntary EMG activity could not have been due to loss of excitability at the neuromuscular junctions or muscle fibre membranes since the M-waves (muscle compound action potentials) evoked by peroneal nerve stimulation were well maintained. The patients and their caregivers are seen together by the nurse practitioner initially for a physical assessment. Impact of dexmedetomidine-sevoflurane anesthesia on intraoperative wake-up test in children patients undergoing scoliosis surgery.

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Truth-telling and deception in the management of nonorganic vision loss. The number of imaging modalities available to stage and follow-up patients with primary neoplasms of the gastrointestinal (GI) tract continues to increase. Anatomo-pathological corneal changes following epidemic keratoconjunctivitis. Four hundred seventy-two patients met the inclusion and exclusion criteria and had an initial estimated glomerular filtration rate (eGFR) between 35 and 80 mL/min per 1.73 m2. The ODSI questionnaire was validated using the Epworth Sleepiness Scale considered as a gold standard. Regulatory T cells were sorted according to expression of CD25 and CD45RA and expanded in the presence of a physiological relevant concentration of TAC. This study is the first to show that it is of great importance to question methods measuring CR proxies in order to develop a clinical tool allowing a comprehensive and accurate estimation of CR.

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Depending on the cell line tested this activation required or was independent of the CD95 receptor/ligand system. In addition, our results highlight the relation between these control processes and others such as prospective memory and maintenance of future intentions. Four genotypes of Sorghum bicolor (L.) Moench were screened in a dry-down experiment using different approaches to discover physiological and molecular indicators of drought tolerance. Children are at risk for injury even if they are not active recreational participants. The maximum value of 3-point bending test on experimental sides was 11.7 times greater than that of the control sides.

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The 2015 European Guidelines on Diagnosis and Treatment of Pulmonary Hypertension are also valid for Germany. We present a case of a newborn infant with bilateral dacryocystocoeles with intranasal extension (intranasal mucocoeles) causing respiratory distress and feeding difficulties. To create a simple, concise and readily usable AF severity score to facilitate treatment decisions and physician communication. Erythrocyte phosphate metabolism and pH in vitro: a model for clinical phosphate disorders in acidosis and alkalosis. The isolation and characterization of lysosomal particles from myxamoebae of the cellular slime mould Dictyostelium discoideum. It is the optimal treatment for isolated, symptomatic, and hemodynamically significant MBs resistant to maximally tolerated medical therapy. Times of eruption of third molars were studied in rural Nigerian adolescents--125 males and 133 females.

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Influence of Different Three-Dimensional Open Porous Titanium Scaffold Designs on Human Osteoblasts Behavior in Static and Dynamic Cell Investigations. A technical inhalation test variant for improving the effectiveness of the use of dose aerosols. Since the studies included are not robust, and there are arguments to support the effectiveness of methotrexate, the evidence observed with the treatment of DMARDs in PsA is not conclusive. There were 22 patients studied, 12 of whom did not undergo distal pancreatectomy (group 1), and 10 who did (group 2). Radiation therapy influence on bone healing around 3 types of endosseous dental implants in dogs was evaluated. Results confirm that the addition of ER (900 mg/d) to standard treatment improves outcomes in patients with AECOPD. Cytogenetic evidence of clonal proliferation of leukemic progenitor cells from patients with acute promyelocytic leukemia (APL). We conclude that complex formation between RET and other RTKs may cause RTK inhibitor resistance. Hepatitis B immunisation for newborn infants of hepatitis B surface antigen-positive mothers.

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Mutations in fused in sarcoma (FUS), a DNA/RNA binding protein, are associated with familial amyotrophic lateral sclerosis (ALS). However, obvious tumor hemorrhage happened in two eyes and affected laser therapy. In the period 70 to 76 hours after planting, the growth rate of the compensated coleoptiles was significantly less than that of the vertically rotated seedlings. There was a significant increase in intestinal permeability in the malnourished patients in association with phenotypic and molecular evidence of activation of lamina propria mononuclear cells and enterocytes, and a heightened acute phase response. The co-melted sample absorbed hydrogen at its maximum capacity in less than three hours without any pre-treatment. Ankle, knee, and trunk power increased and hip power decreased in the anterior malaligned squat compared to the control squat. Dacryocystorhinostomy by nasal endoscopy: an example of multidisciplinary collaboration. In this case report, we describe an outbreak of methanol intoxications that was challenging from a public health perspective and discuss strategies for managing such an outbreak. Comparison of FNAC smears, cytospin smears, and cellblocks of transthoracic guided FNAC of suspected lung tumor: A study of 100 cases.

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Outcomes of open primary repair in patients with proximal tears were excellent, which confirms there may be a potential role for primary repair as treatment for proximal ACL tears. We found 6 cadaveric studies, 2 studies from the general population reporting complete tears, and 10 articles on nontraumatic shoulder pain in the general population that met our criteria. Examination of a prenatal syphilis screening program, Alberta, Canada: 2010-2011. The principle of operation includes the simultaneous transfer of the entire batch of samples, in which a spring-loaded air cylinder generates positive pressure and flexible silica capillaries transfer the samples. Combined arsenic and retinoic acid treatment enhances differentiation and apoptosis in arsenic-resistant NB4 cells. Further investigational directions in intravascular radiation therapy are also presented. The effects of a single 20-mg APD infusion on biochemical parameters of calcium and bone metabolism were investigated during 2 months in 10 healthy male volunteers. The purpose of this study was to describe the experience of foster parents of cocaine-exposed infants. Erratum: Comprehensive evaluation of serum microRNAs as biomarkers in multiple sclerosis.

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Of the 81 parents bearing live infants, 75 remained in complete remission. Among these the alkaloids acetylgynuramine, gynuramine, integerrimine, neoplatyphylline, platyphylline, rosmarinine, senecionine, and seneciphylline were able to bind the antibody. A sample of 161 pregnant women from Athens, Greece was followed up during pregnancy, labor and the first 40 weeks of lactation. The Role of RNA Interference in Stem Cell Biology: Beyond the Mutant Phenotypes. However, the molecular mechanisms underlying these important processes have long remained obscure. A future study should assess the effectiveness of this training in a larger sample and its impact on skills during actual emergencies. Childhood adversity predicts adolescent suicidal ideation but there are few studies examining whether the risk of childhood adversity extends to suicidal ideation in midlife. An integrated proteomic and transcriptomic analysis of perivitelline fluid proteins in a freshwater gastropod laying aerial eggs. Tadpole growth and development has been found to be largely nitrogen (N) limited, as predicted for organisms developing N-rich tissues like muscle.

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Twenty patients with liver metastasis from CRC who underwent baseline and after chemotherapy CT, were retrospectively included. We also assessed the placement of foreign authors relative to the first author in paper bylines of biomedical research articles, which demonstrated a significant citation advantage of having an international presence in the second-to-last author position, possibly occupied by foreign primary co-investigators. Hypothetical intermediate structures are used, each of which is obtained from the procedure where one or more subunits in deoxy Hb are replaced by the corresponding CO-liganded subunits in carbonmonoxy Hb using the method of superimposition of two sets of atomic coordinates. This suggested approach of utilizing pattern recognition tools will be quite useful for regulatory agencies in predicting toxicological interactions occurring in complex chemical mixtures in the environment. All consecutive patients with RYGB and a diagnosis of chronic abdominal pain, and a negative diagnostic workup (including physical examination, routine laboratory work, cross-sectional imaging, and standard upper endoscopy), who underwent device-assisted enteroscopy for evaluation of the gastric remnant, were included. A water-assisted nucleophilic mechanism utilized by BphD, the meta-cleavage product hydrolase in biphenyl degradation. In persons with asymptomatic HIV infection, electrophysiologic tests may be the most sensitive indicators of subclinical neurologic impairment. Congenital heart disease is a significant risk factor in heart transplantation.

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A high-throughput parallel HPLC-MS/MS assay will ventolin show up on a drug test for pantoprazole has been developed and validated. Platelets from 20 normal pigs, nine pigs classified as stress-susceptible on the basis of their response to halothane challenge, and 11 siblings of halothane reactors belonging to two different breeds were subjected to electron microscopic examination. In addition, two different data sets including real and synthetic banknote fragments of different countries were created to test the success of proposed method. Our results reveal some of the underlying mechanisms that make PPR wetlands biogeochemical hotspots, which ultimately leads to their critical, but poorly recognized role in regional greenhouse gas emissions. Comparison of Hemostasis Times With a Kaolin-Based Hemostatic Pad (QuikClot Radial) vs Mechanical Compression (TR Band) Following Transradial Access: A Pilot Prospective Study. We used this system to monitor the growth of Spartina foliosa marsh cordgrass and scale insect herbivores at three simulated shore elevations in laboratory mesocosms. Signal transduction by guanine nucleotide-binding proteins: possible molecular basis for multiple forms of Go alpha mRNA. Complete surgical resection remains the cornerstone of treatment.

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Accelerated increase and relative decrease in subjective age and changes in attitudes toward own aging over a 4-year period: results from the Health and Retirement Study. Despite improvement of dialysis technology, cardiovascular mortality of this population remains high. These studies revealed that the diversity and abundance of CD4 T cells specific for HA do not segregate on the basis of whether the HA was derived from human seasonal or avian influenza viruses. The 6 acute myeloid leukaemia (AML) cell lines tested appeared to be more sensitive than the 4 chronic myeloid leukaemia (CML) cell lines. Throughout this study, patients were receiving other medications. These two DR2 can you take motrin and tylenol together while breastfeeding subtypes were also recognized by cellular assay utilizing PLTs generated between HLA-DR2, DQ-identical, DP-identical or incompatible individuals.

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After briefly reviewing the neuropsychological evidence for this division of labor in the human visual system, we explore the evidence for a dissociation between perception and action in neurologically intact individuals. A case of invasive sino-nasal aspergillosis in an immunocompromised child is reported. Changes in Cognitive Function Over 96 Weeks in Naive Patients Randomized to Darunavir-Ritonavir Plus Either Raltegravir or Tenofovir-Emtricitabine: A Substudy of the NEAT001/ANRS143 Trial. A Neutral Effect of Metformin Treatment on Macroprolactin Content in Women with Macroprolactinemia. Calcineurin Inhibitor-Induced Pain Syndrome in ABO-Incompatible Living Kidney Transplantation: A Case Report. High doses of interferon-gamma (INF-gamma) had no effect on this secretion. Our patient was asymptomatic and had bilateral lung transplants, so a conservative watchful waiting approach was adopted. Results from when they began the program versus most recently are provided.

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There are limited genetically informed studies of insomnia and internalizing disorders and few studies of overlap exist with externalizing disorders. Children with atopic dermatitis (AD) have a higher risk for development of food allergies. In contrast only partial inhibition of the stimulatory effect of OSM was observed at the highest concentration of LBP available. It is concluded that the results described as disappointing were not always the product of the stapes operation. Thus it appears that there is not a random concurrence of other developmental abnormalities with NTD but a definite pattern. wo severe reactions following a pulmonary scan in a patient with idiopathic pulmonary haemosiderosis. Prognostic impact of type of preoperative biliary drainage in patients with distal cholangiocarcinoma. Several pharmacological and psychosocial treatments for substance use disorders are solidly evidence-based and improve both individual and public health outcomes. In the second experiment, clinical doctors have conducted a case study in annotating medical terms documents relevant for their research.

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Tadalafil reduces airway hyperactivity and protects against lung and respiratory airways dysfunction in a rat model of silicosis. Mothers with all risk factors had infants with the highest mean birth weights in South Dakota. Clinical Therapeutics has many of the same errors that reportedly exist in other journals. This survey confirms common use of a standardized outline for documenting, communicating, and teaching history-taking and physical examination protocol. Effectiveness and potentials of specific hyposensitizing treatment for allergic rhinitis in children. Moreover, cationic polymers promote drug transfer across intestinal barriers through various mechanisms, including the opening of the tight junctions, and change in uptake pathway. This is a prospective consecutive observational study of PERT in patients with unresectable PC.

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This approach has several inherent limitations that diminish the clinical utility of these measurements because it is intermittent, susceptible to human error, and requires clinical resources. Most recent cases of liver toxicity induced by triptans have been described, but the mechanisms of liver toxicity of these medications have not been clear. Adolescents with Internet Gaming Disorder (IGD): profiles and treatment response. Michael Tomasello: Award for Distinguished Scientific Contributions. Mortality was related to preoperative and peroperative factors as well as findings at physical examination and medication 4-7 days after the drug class of glucophage operation.

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Immunohistochemistry Successfully Uncovers Intratumoral Heterogeneity and Widespread Co-Losses of Chromatin Regulators in Clear Cell Renal Cell Carcinoma. We suggest that hypertensive nephrosclerosis be included in the differential diagnosis of massive proteinuria accompanying azotemia in poorly controlled hypertensives. Few group differences or treatment effects were found in food-ingestion patterns, although there was an indication that both pre- and post-treatment amaryl 2mg tablets anorexics avoided high-fat foods more than controls did. Assessment of 2 cervical screening methods in Mongolia: cervical cytology and visual inspection with acetic acid. The rs137853127, rs200074373 and rs1992950 mutations of the SATB2 gene were investigated in 173 patients with NSCL/P and 176 normal controls using Kbioscience KASPar chemistry, which is a competitive allele-specific PCR SNP genotyping system.

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Normal teeth from patients who were not operated on were used as controls. Does Sacral Nerve Stimulation Improve Continence Through Enhanced Sensitivity of the Anal Canal?. We suggest that MLPA is a good substitute to traditional karyotype. ANOVAs with repeated measures were computed to observe effects on the Symbol-Digit Test, and the Stick Test. The human Lyt-3 molecule requires CD8 for cell surface expression.

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