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Paxmax (Tramadol)

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Paxmax is used for the management of pain in adults. Although it's a little weaker than other opioids, it can still be addictive and habit-forming. Paxmax is available as both an immediate-acting tablet and an extended-release tablet.

Other names for this medication:
Acema, Acuvin, Armadol, Arrestadol, Avdol, Axedol, Cadol, Dolex, Dolfre, Eltram, Inodol, Ivydol, Jpdol, Kevtram, Nobligan, Omodol, Opidol, Orchidol, Paintrol, Ramax, Standol, Takol, Taramol, Tramache, Tramazac, Transic, Trapain, Tridol, Urogendo

Similar Products:
Maxolon, Sustiva, Feldene, Diamox, Cozaar, Mysoline, Czartan, Setuvir, Ulkus, Finabald, Minipril, Estiva, Ladiwin,

Also known as: Tramadol


Paxmax ER is an pain medicine similar to an opioid. This medicine is used to treat moderate to severe pain.

The extended-release form of tramadol is for around-the-clock treatment of pain. This form of tramadol is not for use on an as-needed basis for pain.


Usual Adult Dose for Pain:

Adults (17 years or older): 50 to 100 mg orally every 4 to 6 hours as needed for pain -For patients not requiring rapid onset of analgesic effect: Initial dose: 25 mg orally once a day; titrate in 25 mg increments every 3 days to reach a dose of 25 mg four times a day; thereafter increase by 50 mg as tolerated every 3 days Maximum dose: 400 mg per day.

Usual Adult Dose for Chronic Pain:

Extended-Release (ER): 18 years or older (tramadol-naive): 100 mg orally once a day -Individually titrate in 100 mg increments every 5 days to an effective dose that minimizes adverse reactions -Maximum Dose: 300 mg/day For patients CURRENTLY receiving Immediate-Release (IR) Paxmax: Initial Dose: Calculate 24-hour IR requirement and initiate with a total daily ER dose rounded down to the next lowest 100 mg increment orally once a day Conversion from OTHER Opioids: Discontinue all other around the clock opioid drugs prior to initiating therapy -Initial dose: 100 mg ER orally once a day -Individually titrate in 100 mg increments every 5 days to an effective dose that minimizes adverse reactions -Maximum Dose: 300 mg/day.

Usual Geriatric Dose for Pain:

Dose selection should be cautious generally starting at the low end of the dose range Over 75 years: Maximum dose of Immediate-release: 300 mg per day.

Usual Geriatric Dose for Chronic Pain:

Dose selection should be cautious generally starting at the low end of the dose range Over 75 years: Maximum dose of Immediate-release: 300 mg per day.

Usual Pediatric Dose for Pain:

Paxmax is not recommended for use in pediatric patients 17 years or older: See Adult Dose.

Detailed Paxmax dosage information


Seek emergency medical attention or call the Poison Help line at 1-800-222-1222. An overdose can be fatal, especially in a child or other person using the medicine without a prescription. Overdose symptoms may include severe drowsiness, pinpoint pupils, slow breathing, or no breathing.

Your doctor may recommend you get naloxone (a medicine to reverse an opioid overdose) and keep it with you at all times. A person caring for you can give the naloxone if you stop breathing or don't wake up. Your caregiver must still get emergency medical help and may need to perform CPR (cardiopulmonary resuscitation) on you while waiting for help to arrive.

Anyone can buy naloxone from a pharmacy or local health department. Make sure any person caring for you knows where you keep naloxone and how to use it.


Store the patches at room temperature in a closed container, away from heat, moisture, and direct light.

Keep out of the reach of children.

Do not keep outdated medicine or medicine no longer needed.

Ask your healthcare professional how you should dispose of any medicine you do not use.

Detailed Paxmax dosage information

Side effects

The most common side effects associated with Paxmax are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.


You should not take Paxmax ER if you are allergic to it, or if you have:

severe asthma or breathing problems; a stomach or bowel obstruction (including paralytic ileus); if you have recently used alcohol, sedatives, tranquilizers, or narcotic medications; or if you have used an MAO inhibitor in the past 14 days (such as isocarboxazid, linezolid, methylene blue injection, phenelzine, or tranylcypromine).

Paxmax ER should not be given to a child younger than 12 years old. Paxmax ER should not be given to anyone younger than 18 years old.

Do not give Paxmax ER to anyone younger than 18 years old who recently had surgery to remove the tonsils or adenoids.

Seizures have occurred in some people taking Paxmax ER. Your seizure risk may be higher if you have ever had:

a head injury, epilepsy or other seizure disorder; drug or alcohol addiction; or a metabolic disorder.

Tell your doctor if you have ever had:

breathing problems, sleep apnea; liver or kidney disease; urination problems; problems with your gallbladder, pancreas, or thyroid; a stomach disorder; or mental illness, or suicide attempt.

If you use Paxmax ER during pregnancy, your baby could be born with life-threatening withdrawal symptoms, and may need medical treatment for several weeks.

Ask a doctor before using Paxmax ER if you are breastfeeding. Tell your doctor if you notice severe drowsiness or slow breathing in the nursing baby.

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Validation of the Postgraduate Hospital Educational Environment Measure (PHEEM) in a sample of 731 Greek residents. Experimental Limiting Oxygen Concentrations for Nine Organic Solvents at Temperatures and Pressures Relevant to Aerobic Oxidations in the Pharmaceutical Industry. Major adverse cardiovascular and cerebral events (MACCEs), time to death, and time to major amputation were also analyzed. Although high-level evidence is lacking, this study identified several risk factors associated with complicated diverticulitis. Pharmacodynamic activity of garenoxacin against ciprofloxacin-resistant Streptococcus pneumoniae. Taken together, our findings clarify a novel biological characteristic of malignant PE and ascites in cancer progression and provide a promising and available strategy for cancer patients with recurrent/refractory malignant PE and ascites. Within each domain, several indicators were set, and each indicator was given a statement. Identification and removal of laser-induced noise in photoacoustic imaging using singular value decomposition. AT2 cells were sorted, and purity was evaluated by immunofluorescence and FACS.

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Genetics of mating in members of the Chaetomiaceae as revealed by experimental and genomic characterization of reproduction in Myceliophthora heterothallica. DSRCT should be considered in the differential diagnosis of young women presenting with abdominal distension and multiple masses on imaging. To the best of our knowledge, only 32 cases have been reported in the literature. Dietary intake did not correlate significantly with ADHD symptoms, presence of one or more impulse control disorders, Barratt impulsiveness, or cognitive functioning. Data were collected from cancer patients by interview technique using structured validated questionnaire. Refractory Haematuria Resulting From Peritoneal Dissemination of Metastatic Gastric Cancer: Radiation Therapy For A Nodule Infiltrating The Urinary Bladder. Synthesis, characterization and antimicrobial evaluation of lipid based norfloxacin prodrug. We apply a constant stretching force to single engineered disulfide bonds and measure their rate of reduction by DTT.

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The findings of a partly prospective case control study of chronic fissure-in-ano conducted in two Danish outpatient clinics are reported. Observations and results of a double-target experiment on the concept of multi-stage cancer therapy using healthy subjects. Fourteen seriously burned patients who had pulmonary arterial monitoring. The addition of oral antibiotics to systemic antibiotics could potentially reduce the risk of SSIs in elective colorectal surgery. DRGs, orthopedic surgery, and age at an academic medical center. The study is to assess the employment status and to determine the variables for unemployment in Chinese MHD ventolin inhaler generic price patients. Recent studies highlight cortical demyelinated lesions as a feature of multiple sclerosis (MS) pathology, which has received little attention so far. In-line fiber optic structures for environmental sensing applications.

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Patients with congenital or acquired deformities always need fat graft at least twice to remodel facial contour. The statistical reform movement and the American Psychological Association (APA) defend the use of estimators of the effect size and its confidence intervals, as well as the interpretation of the clinical significance of the findings. The experimental control group consisted of four specimens of uninflamed periodontal ligament tissue. We report here Fos-LI in the hypothalamic, medullary and thoracic spinal cord neurons some of them are believed to be involved in cardiovascular regulation after the cerebral ischaemic insult. Cortical Thickness and Local Gyrification in Children with Developmental Dyslexia.

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Nucleotide sequence of rat liver tyrosine aminotransferase gene fragment. This study aims to improve the prediction on medical services demand in China. MR2 attenuated CBP stress- and conditioned fear stress-induced antinociception, had a protective effect against CBP stress-induced gastric lesions, and restored the hypnotic activity of pentobarbital decreased by CBP stress or social isolation stress to the level of the unstressed controls. In addition, WAXS results show that the short-range spatial correlations into the assemblies of hydrocarbon molecules confined inside the micropores are different from those existing in the liquid phase. To determine whether knee extensor power asymmetry limits functional mobility of older plavix dosage chart adults who possess muscle weakness. All cases of incident PMR among Olmsted County, Minnesota residents in 2000-2014 were identified to extend the previous 1970-1999 cohort.

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Data from phase 2 and 3 clinical trials underscore a rapid decrease of bone mineral density (BMD) and a steep increase in bone turnover markers (BTMs) after discontinuation of denosumab. The aim of this study was to examine the effects of various immunosuppressants on airway epithelium. AMP-Activated Protein Kinase and Sirtuin 1 Coregulation of Cortactin Contributes to Endothelial Function. Pre-processing and transfer entropy measures in motor neurons controlling limb movements. Further research may enable clinicians to discern earlier which patients will benefit from adrenal corticoid replacement. Therefore, it should not be considered as a parameter for the assessment of RSA patients. The study instrument also can be used for further research of case management practice.

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The gastroesophageal junction in the monkey and its relation to reflux. Effect of Ramadan fasting on intragastric pH recorded during 24 hours in healthy subjects. ERK1/2, JNK and STAT3 activation and correlation with tumor differentiation in oral SCC. Although multisensory integration has been demonstrated in saccadic eye movements, its influence on other orienting responses, including pupil size and microsaccades, is still poorly understood. Bias and association of sediment organic matter source apportionment indicators: A case study in a eutrophic Lake Chaohu, China. The modifications introduced result in a substantial improvement of the commonly used coleoptile elongation tests.The proposed test retains the simplicity of physical requirements and of manipulation characteristic of all elongation tests. Since the benefits of chemotherapy in treating older men with metastatic castration-resistant prostate cancer (mCRPC) are modest, validated tools that predict the risk of treatment toxicity may aid clinical decision-making. Studies in animal models and humans with rare monogenic disorders link only particular HDL-associated mechanisms with causality, including those mechanisms related to particle functionality rather than cholesterol content. Both IgG (30 mg/dl) and IgA (15 mg/dl) had a biphasic pattern with peak immunoglobulin levels detected 1 day before the estradiol peak and increasing again just after ovulation.

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Chemical extraction of incinerated sewage sludge ash (ISSA) can effectively recycle P, but it may change the speciation and mobility of the remaining metals. Traumatic skin lesions: prophylaxis and therapy of infection using mezlocillin. Semiconservative DNA replication has provided an elegant solution to the fundamental problem of how life is able to proliferate in a way that allows cells, organisms, and populations to survive and replicate many times over. The relations among marrow metastases, age at diagnosis, and clinical outcome illustrate the biologic heterogeneity of neuroblastoma. No author has a financial or proprietary interest in any material or method mentioned. Finally, if not treated, this inflammation can cause the loss of the implant.

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N-methyl-D-aspartate receptors (NMDARs), ligand-gated ionotropic glutamate receptors, play key roles in normal brain development and various neurological disorders. Tissue engineering and regenerative medicine-based strategies for the reconstruction of functional skeletal muscle tissue have included cellular and acellular approaches. To our knowledge, this is the first case of calcinosis circumscripta in a bird involving a limb extremity, similar to the presentation recognized more commonly in domestic animals. A general survey is followed by an evaluation of the different relevant procedures. ROSE by endosonographers during EUS-FNA for SMT is useful for definitive diagnosis, particularly for GIST. Effects on brain tumor cell proliferation by an adenovirus vector that bears the interleukin-4 gene. The sensitivity of UV-20 cells was also a linear function of concentration and time, but no aerobic/hypoxic differential was observed in these cells. COMT Val158Met polymorphism is associated with post-traumatic stress disorder and functional outcome following mild traumatic brain injury. QRS prolongation after cardiac resynchronization therapy is a predictor of persistent mechanical dyssynchrony. Effusions with intermediate or high T1 signal are most frequently confused with cholesterol granulomas.

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