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Indolam (Alprazolam)

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Indolam is used to treat anxiety and panic disorders. It belongs to a class of medications called benzodiazepines which act on the brain and nerves (central nervous system) to produce a calming effect. It works by enhancing the effects of a certain natural chemical in the body (GABA). Indolam is mostly used to treat anxiety disorders, panic disorders, and nausea due to chemotherapy. Indolam may also be indicated for the treatment of generalized anxiety disorder, as well as for the treatment of anxiety conditions with co-morbid depression. The FDA label advises that the physician should periodically reassess the usefulness of the drug.

Other names for this medication:
Aldep, Aleez, Alfix, Alflux, Alprasan, Alprastan, Alprawin, Alprazan, Alprosym, Alrif, Alsert, Alzokam, Alzolite, Ambutech, Anxico, Anxilam, Anxizam, Ateez, Azoslip, Copax, Cqlam, Dazolam, Depoxit, Dexolam, Enxolam, Ezoprax, Fultop, Imprax, Kaprolam, Mebaspa, Nexlpra, Niravam, Paxor, Rescalm, Resolin, Rozin, Samitol, Sinaday, Sinozol, Somnia, Tagat, Tenan, Tenfree, Tenrid, Tenschem, Tenscure, Wycalm, Zedel, Zolipax, Zolorel

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Also known as: Alprazolam


Alprazolam is used to relieve symptoms of anxiety, including anxiety caused by depression. It is also used to treat panic disorder in some patients.

Alprazolam is a benzodiazepine. Benzodiazepines belong to the group of medicines called central nervous system (CNS) depressants, which are medicines that slow down the nervous system.

This medicine is available only with your doctor's prescription.


Take Indolam XR exactly as it was prescribed for you. Do not take the medication in larger amounts, or take it for longer than recommended by your doctor. Follow the directions on your prescription label.

Your doctor may occasionally change your dose to make sure you get the best results from this medication.

Indolam XR may be habit-forming and should be used only by the person it was prescribed for. Indolam XR should never be shared with another person, especially someone who has a history of drug abuse or addiction. Keep the medication in a secure place where others cannot get to it. Do not crush, chew, or break a Indolam extended-release tablet. Swallow the tablet whole. It is specially made to release alprazolam slowly in the body. Breaking the tablet would cause too much alprazolam to be released at one time.

Contact your doctor if this medicine seems to stop working as well in treating your panic or anxiety symptoms.

Your symptoms may return when you stop using Indolam XR after using it over a long period of time. You may also have seizures or withdrawal symptoms when you stop using Indolam XR.

Withdrawal symptoms may include blurred vision, trouble concentrating, loss of appetite, diarrhea, muscle twitching, numbness or tingling, or increased sensations.

Do not stop using Indolam XR suddenly without first talking to your doctor. You may need to use less and less before you stop the medication completely.

To be sure this medication is helping your condition, your doctor will need to check your progress on a regular basis. Do not miss any scheduled visits to your doctor.

Store Indolam XR at room temperature away from moisture, heat, and light. Remove any cotton from the bottle of disintegrating tablets, and keep the bottle tightly closed.

Keep track of how many pills have been used from each new bottle of this medicine. Benzodiazepines are drugs of abuse and you should be aware if any person in the household is using this medicine improperly or without a prescription.

Detailed Indolam XR dosage information


Seek emergency medical attention if you think you have used too much of this medicine. An overdose of Indolam XR can be fatal.

Overdose symptoms may include extreme drowsiness, confusion, muscle weakness, loss of balance or coordination, feeling light-headed, fainting, and coma.


Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing.

Keep out of the reach of children.

Do not keep outdated medicine or medicine no longer needed.

Ask your healthcare professional how you should dispose of any medicine you do not use.

It is very important to protect the orally disintegrating tablets from moisture. Remove and throw away any cotton packaging from the medicine bottle when you first use the medicine.

Detailed Indolam XR dosage information

Side effects

The most common side effects associated with Indolam are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.


Tell your doctor if you have ever had any unusual or allergic reaction to this medicine or any other medicines. Also tell your health care professional if you have any other types of allergies, such as to foods, dyes, preservatives, or animals. For non-prescription products, read the label or package ingredients carefully.

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Differential diagnosis of myxoid fibromatous tissues of the jaw-bones in children and adolescents. These changes were concomitant with decreased levels of BDNF mRNA in the gastro-intestinal tract and increased expression of TrkB mRNA in the brain. To assess longitudinal trajectories of overall disability after moderate-to-severe traumatic brain injury (TBI) and to examine whether those trajectories could be predicted by socio-demographic and injury characteristics. Drosophila Vps13 mutants are suitable to investigate the function of Vps13 in the brain, to identify genetic enhancers and suppressors and to screen for potential therapeutic targets for Chorea-Acanthocytosis. Deoxycytidine (dCyd) kinase is required for the phosphorylation of several deoxyribonucleosides and certain nucleoside analogs widely employed as antiviral and chemotherapeutic agents.

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Single Anastomosis Sleeve Ileal Bypass: New Step in the Evolution of Bariatric Surgeries. We developed a short computerized face-name associative recognition test (FNART) and tested whether it would detect memory impairment in memory clinic patients with mild cognitive impairment (MCI) and subjective cognitive decline (SCD). Core and penumbral nitric oxide synthase activity during cerebral ischemia and reperfusion. To determine a possible (eco)toxicological risk, aquatic samples are tested using various bioassays, including sub-organismic assays such as the luminescent bacteria inhibition test, the acetylcholinesterase inhibition test, and the umu-test. The distribution and orientation of biological apatite crystals in calcified turkey leg tendons were studied by selected-area dark field electron microscopy. Attributed to the high temperature coefficient of resistance of VO2, the enhanced breath sensing performance was demonstrated and the response time and recovery time can be as fast as 0.5 s. Based on the evidence available, the relevance of follow-up per se must even be challenged.

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Transcriptomic profile of tobacco in response to Tomato zonate spot orthotospovirus infection. Recently it has been demonstrated that p38MAPK (mitogen-activated protein kinase) inhibition using SB203580 is effective in reducing disease in both dextran sulphate sodium (DSS)-induced and 2,4,6-trinitrobenzenesulphonic acid (TNBS)-induced murine colitides, underscoring the importance of this pathway in gastrointestinal inflammation. Characterization of the universal Russian reagent sets for real-time PCR and its application for molecular oncodiagnostic. Chitosan stabilized Ag-Au nanoalloy for colorimetric sensing and 5-Fluorouracil delivery. Inflammatory bowel diseases (IBD) can affect women of childbearing potential. The increased use of laparoscopy has resulted in certain complications specifically associated with the laparoscopic approach, such as port-site incisional hernia (PIH). Prevalence of alcohol misuse among adolescents and young adults evaluated in a primary care setting. Airway myeloid dendritic cells (mDCs) and plasmacytoid dendritic cells (pDCs) are professional antigen-presenting cells.

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The BTL Vanquish METM system has been thoroughly redesigned for more efficient, predictable and homogenous energy delivery to the targeted tissue. The recent Ebola virus epidemics which threatened three West African countries (Dec.2014-Apr.2016) has urged global collaborative health organizations and countries to set up measures to stop the infection and to treat patients, near half of them being at risk of death. The report also documents the rare occurrence of elevated serum CEA in a primary benign intracranial tumor. Immunosuppressive therapy of myocarditis appears to be justified only after exclusion of persistent heart muscle infection. pylori infection, and 246 with altered expression as a combined result of FAF1 expression and H. The effect of probing on the rate of formation and growth of lesions was quantified in vitro. Prevention of endotoxin shock through targeting leukocyte adhesion molecules. A basic overview of the types of qualitative research, methodological procedures, and ethical considerations is provided.

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The use of synthetic peptides in the serological diagnosis of infectious diseases has proved to be a valuable strategy because in some cases, the reactions are more specific and sensitive. Furthermore, these results support the hypothesis that benzodiazepine receptor partial agonists are less likely to induce physical dependence than full agonists. We show here, through behavioral experiments, that the nymphalid butterfly Heliconius erato, although it expresses short and medium wavelength opsins and only one long wavelength opsin, discriminates colors in the long-wavelength range (590 nm, 620 nm and 640 nm), whereas another nymphalid, Vanessa atalanta, despite having color vision, is unable to do so. Platinum-functionalized octahedral silica nanocages: synthesis and characterization. Key domains of the questionnaire include the layout of service functions, environment maintenance, process management, quality of care, humane care and the patient-doctor relationship. Saving Mothers, Giving Life (SMGL) is a multi-partner initiative designed to reduce maternal mortality rapidly in high mortality settings through community and facility evidence-based interventions and district-wide health systems strengthening that could reduce delays to appropriate obstetric care.

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Aryl hydrocarbon receptor-deficient mice are protected from high fat diet-induced changes in metabolic rhythms. It is known that the calcium comprising the spicules comes from the seawater and we wish to further consider the mode of calcium transport from the extracellular seawater to the PMCs and then onto the forming spicules. Despite the growth of the Active nursing workforce, the skewed distribution of nurses in the below 35 age group and the growth in the Eligible category, especially for nurses living abroad, raise concerns on the longevity of nurses in the profession and the reasons for their attrition from the workforce. In the multicellular embryo, evidence is accumulating for roles of cell wall and intercellular communication via diffusible signals in pattern formation and control of cell fate. However, determining its true diagnostic value will require larger studies with control subjects and control methods such as coronary angiography. SESLO image quality benefited from single-mode illumination and multimode collection through a prototype double-clad fiber coupler, which optimized scattered light throughput and reduce speckle contrast while maintaining lateral resolution. During this period, the only germ cells present in the gonad are primordial germ cells. The mosquito larvae predation rates of tadpoles of three common Thai anuran species (Bufo melanostictus, Kaloula pulchra and Hylarana raniceps) were experimentally tested. Magnetic resonance imaging of a coronary fistula manifesting as a pericardial effusion. These metabolites are a well-known class of centrally active compounds and their formation may therefore be a pharmacologically significant pathway, at least in certain species, for derivates that undergo extensive cleavage of the arylpiperazine side-chain.

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On-line solid-phase extraction-ultra high performance liquid chromatography-tandem mass spectrometry for the determination of avermectins and milbemycin in soils. Importantly, dietary addition of specific polyunsaturated FAs partially suppressed these pleiotropic phenotypes. Astrocyte progression from G1 to S phase of the cell cycle depends upon multiple protein interaction. Implications for therapy with clinical populations are discussed. T2 relaxation times increased significantly (p less than .01) in all volunteers, but T2 relaxation times for the muscles that performed concentric actions were significantly higher than those for muscles that performed eccentric actions (p less than .01). pylori genotypes like cagA, vacA s1 or babA1 are considered to be of higher virulent potential. Ceftazidime-induced hemolysis in a patient with drug-dependent zyloprim 100 mg antibodies reactive by immune complex and drug adsorption mechanisms.

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The results showed that SBI with two extracted components is suitable for cross-cultural analysis between Finnish and Chinese university students. Th1- and Th2-type cells mediate distinct effector functions via cytokine secretion in response to immunologic challenge. CAN AN ENERGY-COMPENSATED SOLID-STATE X-RAY DETECTOR BE USED FOR RADIATION PROTECTION APPLICATIONS AT HIGHER PHOTON ENERGIES?. Unsaturated fatty acids were further tested against SK-BR-3 hormone-independent human breast cancer cells that overexpress aromatase and were found to be inactive. Primary benign fibrous histiocytoma involving the central nervous system is an exceedingly rare tumor with most cases originating from the dura or parenchymal tissue. A group of bone changes may be associated with disorders of the endocrine system. These studies establish the conditions and verify the reliability and accuracy of the vaccinia virus expression system for studies on the enzymology of IIA1 and IIA2.

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The results show that, while the mechanical strain displaces the energy levels and changes the band gap in the nanotube caps, the applied bias breaks the degeneracy in the nanotube cap states and defines the electrical conductance along the system. Adaptation and Validation of a Pediatric Sequential Organ Failure Assessment Score and Evaluation of the Sepsis-3 Definitions indocin medication indomethx in Critically Ill Children. We used multinomial logistic regression to estimate relative risk ratios (RRRs). Animal development depends on not only the linear genome sequence that embeds millions of cis-regulatory elements, but also the three-dimensional (3D) chromatin architecture that orchestrates the interplay between cis-regulatory elements and their target genes. However, phyllospheric bacterial communities are highly variable depending on several factors, e.g. Selective D2 dopamine receptor agonists prevent catalepsy induced by SCH 23390, a selective D1 antagonist. We have further develop this approach for making hydrophobic substrates.

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Elemental analysis showed that both tetracycline names of antibiotics pigment deposits and stratum corneum of hyperpigmented skin samples contained iron and calcium. Our findings support other epidemiological data of a high incidence of SAP with severe neurological deficits on admission and dysphagia in an SCU setting. states over 2000-2009 using a dataset of HIV/AIDS case rates and AIDS deaths per 100 000 people matched with a unique dataset of state-level spending on social services and public health per person in poverty. Modifications of the liberation of the mediator at the neuromuscular junction under the effect of the uranyl ion. Aberrant DNA methylation was responsible for down-regulation of microRNA-124a by regulating the mitogen-activated protein kinase pathway, suggesting that microRNA-124a is a potential diagnostic biomarker in congenital spina bifida. Twenty-two mesial roots of extracted human mandibular molars were divided into two groups based on root curvature and length.

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Phytochemical analysis and in vitro anthelmintic activity of Lophira lanceolata (Ochnaceae) on the bovine parasite Onchocerca ochengi and on drug resistant strains of the free-living nematode Caenorhabditis elegans. Whereas Mn in blood was not associated with any neurometabolite content in these VOIs, a higher metal accumulation in the GP assessed with R1 correlated with generally lower neurometabolite concentrations. We retrospectively reported our 26-year experience with operative repair of total anomalous pulmonary venous connection (TAPVC) with biventricular physiology. Pharmacokinetics and metabolism of epidoxorubicin and doxorubicin in humans. Hemodynamic changes in primary somatosensory cortex covaried positively with neuronal activity in a predominantly linear manner, with a small quadratic contribution. The role of Quantiferon-TB Gold in-Tube in the diagnosis and treatment monitoring of active tuberculosis. HSV1 encodes three tail-anchored proteins pUL34, pUL56 and pUS9 characterized by a single hydrophobic region positioned at their C-terminal end that needs to be released from the ribosome prior to posttranslational membrane insertion.

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In this case-control study, PD patients undergoing STN DBS experienced post-operative weight gain that was significantly different from the weight loss observed in non-DBS PD controls. For the first time, the propagation properties of spatiotemporal CAiGV light bullets in the quadratic index medium are demonstrated. Two classification systems based on detailed dorsal hand cutaneous innervation patterns can be used to specify the placement of a safe dorsal skin incision away from major nerve branches. Efficacy and safety of intravenous nicardipine in the control of postoperative hypertension. Dose response relation to oral theophylline in severe chronic obstructive airways disease. A gender-based approach to multiple sclerosis could provide further benefits for its treatment and management.

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Induction of tumors with diet low in vitamin B6 containing N-2-fluorenylacetamide after single dose of cyclophosphamide. The nest flea index of Meriones unguiculatus is a critical indicator for the prevention and control of plague, which can be used not only to detect the spatial and temporal distributions of Meriones unguiculatus, but also to reveal its cluster rule. Mitral stenosis (MS) is found to produce left ventricular (LV) dysfunction in some studies. Urine culture contamination can be reduced with proper techniques for urine collection, preservation, storage, and transport, the major factors affecting the preanalytic phase of urine culture. Everolimus is more hydrophilic by virtue of differing from sirolimus by one hydroxyl group. From January 1999 to December 2001, 295 patients were treated with a permanent prostate implantation (real-time technique, with free (125)I seeds) by the Paris Institut Curie/Hospital Cochin/Hospital Necker Paris group.

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