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Fasigyn (Tinidazole)
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Fasigyn

Fasigyn 500mg film-coated tablets contain 500mg of the active substance tinidazole. This medicine is an anti-infective agent. It is used to treat a variety of bacterial infections. It is also used before certain surgical operations to prevent bacterial infections developing.

Other names for this medication:
Simplotan, Tindamax, Tinidazole

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Alprostadil, Celexa, Arava, Uroxatral, Naprosyn, Lioresal, Medrol, Adalat, Amaryl, Finast, Dilcor, Bezip, Alerflo, Diavista, Cefix, Retoz,

Also known as: Tinidazole

Description

Fasigyn 500mg film-coated tablets contain 500mg of the active substance tinidazole. This medicine is an anti-infective agent. It is used to treat a variety of bacterial infections including: infections of the skin, blood, chest, lung, genitals or womb lining, an infection associated with stomach ulcers in combination with other drugs, infections caused by organisms called protozoa, such as amoebiasis and giardiasis (stomach infections) and trichomoniasis (a genital infection), vaginal infections (vaginitis) and gum infections (gingivitis).

It is also used before certain surgical operations to prevent bacterial infections developing.

You should ask your doctor if you are unsure why you have been given this medicine.

Dosage

Fasigyn tablets should be taken with plenty of water with or after meal. Swallow Fasigyn tablets whole, do not chew or crush. Fasigyn is not recommended for use in children less than 12 years. For urogenital Trichomoniasis: The recommended dose is 4 tablets (2 g) given as a single dose. For amoebic involvement of the liver (a liver infection): the recommended dose is 3 to 4 tablets (1,5 to 2 g) once a day for 3 to 6 days. For the infection associated with stomach ulcers: the recommended dose is 1 tablet (500 mg) taken twice a day. For most bacterial infections: the recommended dose is 4 tablets (2 g) on the first day then 2 tablets (1 g) once a day or 1 tablet (500 mg) twice a day. The usual length of treatment is 5 to 6 days. For bacterial vaginitis (a vaginal infection) and acute ulcerative gingivitis (a gum infection): the recommended dose is 4 tablets (2 g) given as a single dose. For vaginitis you may be given 4 tablets (2 g) on two consecutive days. For protozoal infections (intestinal amoebiasis): the recommended dose is 4 tablets (2 g) once a day for 2 to 3 days. Prevention of postoperative infections in adults (over 12 years): the recommended oral dose of 2 g approximately 12 hours before surgery.

Overdose

Immediately telephone your doctor or go to Accident and Emergency (Casualty) at your nearest hospital if you think you or anyone else may have taken too much Fasigyn. Do this even if there are no signs of discomfort or poisoning. You may need urgent medical attention. Keep telephone numbers of these places handy.

If you take too many tablets, you may get an upset stomach, diarrhoea or skin rashes.

Storage

Keep Fasigyn in its original packaging until it is time to use it. If you take Fasigyn out of its packaging, it may not keep as well.

Keep your Fasigyn in a cool, dry place where it stays below 25 degrees C.

Do not store Fasigyn or any other medicine in the bathroom or near a sink. Do not leave it in the car or on a window sill. Heat and dampness can destroy some medicines.

Keep your Fasigyn where young children cannot reach it. A locked cupboard at least one and a half metres above the ground is a good place to store medicines.

Side effects

The most common side effects associated with Fasigyn are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.

Contraindications

Do not take Fasigyn if you are allergic to: Fasigyn, any ingredients listed at the end of the leaflet, or related medicines such as Simplotan, Flagyl, Metrogyl and Metozine (not all brands given). If you are not sure if you are allergic to any of the above, ask your doctor. Symptoms of an allergic reaction include: asthma, wheezing or shortness of breath, swelling of the face, lips or tongue which may lead to difficulty swallowing or breathing, hives, itching, skin rash or redness of skin, fainting, light-headedness.

Do not take Fasigyn if you have a history of any blood disorder.

Do not take Fasigyn if you have any disease of the brain, spinal cord or nerves.

Do not take Fasigyn if you are pregnant or intend to become pregnant. Your doctor will discuss the risks and benefits of taking Fasigyn during pregnancy (pregnancy up to four months).

If you are a woman of child-bearing age, make sure you do not become pregnant while taking Fasigyn.

Do not take Fasigyn if you are breastfeeding. Like many other medicines, Fasigyn passes into breast milk and may harm your baby.

Do not breastfeed your baby while taking, and until at least three days after stopping Fasigyn.

If you are not sure whether you should be taking Fasigyn, talk to your doctor.

Do not take Fasigyn if the expiry date (EXP) or use by date printed on the pack has passed. If you take this medicine after this date, it may not work.

Do not take Fasigyn if the packaging is torn or shows signs of tampering. If this is the case, return it to your pharmacist.

If you are not sure whether you should start taking Fasigyn, talk to your doctor.

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MgO Nanoparticle Modified Anode for Highly Efficient SnO2-Based Planar Perovskite Solar Cells. Levels of interleukin (IL)-1beta, IL-6, interferon (IFN)-gamma and tumour necrosis factor (TNF)-alpha increased as did C1-INH, C3, C4, CRP, and lactate dehydrogenase. Iron deficiency alters expression of genes implicated in Alzheimer disease pathogenesis. The purpose of this descriptive study was to examine quality of life (QOL) in adult patients with sickle cell anemia, hemoglobin SC, or hemoglobin S beta thalassemia. Here, we present an overview of evaluation techniques for high-throughput experimental data and computational methods, and we discuss a number of potential pitfalls in this process. Initially, a single stent was placed to relieve the obstruction, followed by placement of an Amplatzer septal occluder device which assumed suboptimal position after release. Since changes in the fertilization pattern of phosphotyrosyl proteins occurred during formation of the sperm aster and mitotic spindle, we analyzed the role of protein tyrosine kinase activity in these processes using the tyrosine kinase specific inhibitor, erbstatin. Agroinfiltration has proven very useful for the overexpression of proteins in the infiltrated zone when a short-term effect can be informative. If this observation is replicated in other populations, it may provide further impetus for a stronger recommendation for early detection with PSA and digital rectal examination. In this study we have demonstrated that polymerase chain reaction (PCR) and nested PCR methods enabled detection of Babesia caballi and Babesia equi in field isolates of Dermacentor nuttalli adult ticks from Mongolia.

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Chronic high-frequency stimulation therapy in hemiparkinsonian rhesus monkeys using an implanted human DBS system. The authors evaluate the first results of pre and postoperative refraction after implantation of ten toric intraocular lenses. Glutathione S-transferase activity and glutathione content in human bladder carcinoma associated with schistosomiasis: comparison with uninvolved surrounding tissues. Increase in nephrology advanced trainee numbers in Australia and associated reduction in clinical exposure over the past decade. A characteristic gapped spin liquid behavior is observed at ultralow temperature. Information was gathered from the annual reports of the Austrian Mountain Rescue Service, the Swiss Alpine Club Rescue Station in Zermatt, the Mountain Rescue Service of the Southern Tirol Alpine Club, the Mountain Rescue Service of the Bavarian Red Cross, and the Department of Mountain Medicine and Traumatology from the Hospital in Chamonix. Hyperinsulinemia was exaggerated by dextrose administration, but was successfully treated with octreotide. We report on a 44-year-old woman presenting with chest pain and dyspnoea without previous stress-related events.

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Synthesis, biological activity, and solution structures of a cyclic dodecapeptide from the EGF-2 domain of blood coagulation factor VII. Regio- and stereoselectivity of captodative olefins in 1,3-dipolar cycloadditions. Twenty-nine patients with advanced renal carcinoma and eleven patients with lymphoma were treated with poly ICLC. Eleven schools chosen at random in Madrid City and the surrounding area. Moment arms of muscle forces with respect to joints are useful parameters in muscle-function analysis.

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Functional magnetic resonance imaging brain mapping in psychiatry: methodological issues illustrated in a study of working memory in schizophrenia. Tenosynovial giant cell tumor (TSGCT) is a highly recurrent benign tumor of the extremities. Despite maximum conventional therapy with a combination of different kinds of lipid-lowering drugs, sometimes the goal of therapy cannot be reached. In humans, an increase or decrease in erythrocyte CA II activity is correlated with an increase or decrease in gastric acid secretion. The past couple of years saw exciting new developments in microchip-based gene synthesis technologies. Megaprepuce is a congenital penile malformation that includes phimosis and severe ballooning of the internal prepuce.

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Intranasal administration of crushed ALO-02 (extended-release oxycodone with sequestered naltrexone): A randomized, controlled abuse-potential study in nondependent recreational opioid users. However, the latter corrinoid protein could also serve as methyl acceptor for the veratrol:corrinoid protein methyl transferase. Advantage of biological over physical optimization in prostate cancer?. A set of friedelane triterpenoids has been isolated from the stem bark exudates of Maytenus macrocarpa. To investigate whether Annexin V provides a marker of apoptosis in the central nervous system we carried out histochemical analysis of its binding in the 21-day-old rat brain at various time-points following a moderate unilateral hypoxic-ischemic (HI) insult. In the surgical strategy of lower limb varicose veins, the fundamental objective is to prevent relapses. Due to the changing population structure, the proportion of aged men has increased, whereby there is an increasing need for the treatment of prostatic hyperplasia. Both KiSS1 overexpression and KP10 (kisspeptin-10) stimulation inhibited TNFalpha-induced NF-kappaB activity, suppressed TNFalpha-induced cell migration and cell attachment to fibronectin in breast cancer cells while KP10 has little effect on cancer cell proliferation. Nevertheless, complication rates are high and patients must be warned that multiple revisions will be necessary throughout their lifetime.

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To define the ubiquitination-dependent step in the trafficking pathway, we examined the intracellular localization of Ste6 in the ubiquitination-deficient doa4 mutant by immunofluorescence experiments, with a Ste6-green fluorescent protein fusion protein and by sucrose density gradient fractionation. While bacterial P450 enzymes typically show higher activity, they tend to be highly selective for one or a few substrates. Methods used to compare data from different networks are described. Ischemic dose-response in the spinal cord: both immediate and delayed paraplegia. Effect of prone positioning in patients with acute respiratory distress syndrome and high Simplified Acute Physiology Score II. Automatic word processing can be used with some patients to gain important insights and therapeutic successes that might not be achieved as easily by other means. Instead, we found that protein kinase C-related kinase, a Rho-dependent serine/threonine kinase, is activated in endothelial cells upon thrombin stimulation and that its expression is required for endothelial permeability and the remodeling of cell-extracellular matrix and cell-cell adhesions. Understanding and correcting for carbon nanotube interferences with a commercial LDH cytotoxicity assay.

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In contrast, constitutively active forms of Bim and Bad failed to induce apoptosis in bax(-/-)bak(-/-) cells. A set of audiological tests is introduced that has been validated and optimized by empirical investigations in adult cochlear implant users. A total of 366 records were screened, 38 full-text articles were reviewed, and 14 published studies were included. Human immunodeficiency virus/hepatitis C virus co-infection: do we have the right not to treat our patients?. Laparoscopic and robotic-assisted approaches are able to duplicate the open technique, and not surprisingly duphaston tablet benefits , are now being shown to be as efficacious as the gold standard open approach. Detection of integrated human papillomavirus 16 DNA in squamous cell carcinoma of the cervix.

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Chronic treatment of SH rats with pioglitazone decreased plasma insulin levels and blood pressure. Primary antiphospholipid antibody syndrome and autoimmune haemolytic anaemia--a rare combination. The aim of this study was to investigate the effects of surgical left atrial reduction in chronic atrial fibrillation by mitral valvulopathy. The remarkable increase in the photocatalytic performance of these materials toward the degradation of a model organic Congo red dye correlates to an increase of 2.7-fold over that of anatase TiO(2) after adding Au to it and 4.3-fold after introducing PTA along with Au to it. Predicting one-year mortality in peritoneal dialysis patients: an analysis of the China Peritoneal Dialysis Registry. Taken together, neuroimaging studies indicate that OCD symptoms are mediated by hyperactivity in orbitofrontal-subcortical circuits, which may be attributable to an imbalance of tone between aricept 10 generic direct and indirect striato-pallidal pathways. The authors have identified and managed a large number of complications in this series, although the rate of complications is consistent with that in other reported series. Rates of allergic sensitization and irritation to oxybenzone-containing sunscreen products: a quantitative meta-analysis of 64 exaggerated use studies. Additionally, the dependency on loading conditions and contractility was preserved, suggesting that normal regulatory interactions for efficiency are intact and that sympathetic tone does not play a role under resting conditions.

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