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Dramamine (Dimenhydrinate)

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Dramamine is used to treat many different inflammatory and allergic conditions. It works by lowering your immune system’s response to these conditions and prevents the release of substances in the body that cause inflammation. Dramamine helps relieve symptoms such as swelling, pain, itching, and other allergic-type reactions.

Other names for this medication:
Dimenhydrinate, Dramnate, Gravol, Transmine, Triptone

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Klonopin, Zocor, Levothroid, Lopressor, Rocaltrol, Amoxil, Prandin, Bystolic, Valtrex, Dinid, Valtec, Ectin, Ganaton, Waklert, Simvastatina, Renitec, Novolen,

Also known as: Dimenhydrinate


Meclizine is used to prevent and control nausea, vomiting, and dizziness caused by motion sickness. It is also used for vertigo (dizziness or lightheadedness) caused by ear problems.

Meclizine is an antihistamine. It works to block the signals to the brain that cause nausea, vomiting, and dizziness.

This medicine is available only with your doctor's prescription.


This section provides information on the proper use of a number of products that contain meclizine. It may not be specific to Dramamine II. Please read with care.

Take this medicine only as directed by your doctor. Do not take more of it, do not take it more often, and do not take it for a longer time than your doctor ordered.

Chew or crush the chewable tablet completely before swallowing. Do not swallow it whole.

Swallow the non-chewable tablet whole. Do not crush, chew, or break it.

The dose of this medicine will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of this medicine. If your dose is different, do not change it unless your doctor tells you to do so.

The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.

For oral dosage form (tablets): For nausea, vomiting, and dizziness caused by motion sickness: Adults—At first, 25 to 50 milligrams (mg) taken 1 hour before travel. You may take another dose once every 24 hours while traveling. Children 12 years of age and older—Use and dose must be determined by your doctor. Children younger than 12 years of age—Use is not recommended. For vertigo: Adults—25 to 100 milligrams (mg) per day, taken in divided doses. Children—Use and dose must be determined by your doctor.


Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.

Overdose symptoms may include extreme drowsiness, irritability, dilated pupils, hallucinations, or seizure. In children, an overdose may cause irritability or restlessness followed by severe drowsiness.


Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing.

Keep out of the reach of children.

Do not keep outdated medicine or medicine no longer needed.

Ask your healthcare professional how you should dispose of any medicine you do not use.

Detailed Dramamine II dosage information

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The most common side effects associated with Dramamine are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.


Tell your doctor if you have ever had any unusual or allergic reaction to this medicine or any other medicines. Also tell your health care professional if you have any other types of allergies, such as to foods, dyes, preservatives, or animals. For non-prescription products, read the label or package ingredients carefully.

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We demonstrated Fourier synthesis of a new type of multiple coherent anti-Stokes Raman scatterings in KTaO(3) crystal. During spring 2011, a great epidemic of entero-hemorrhagic Escherichia coli (EHEC) associated HUS occurred in Germany, providing clinicians the opportunity to examine the relevance of antibiotic prophylaxis, plasma exchange and eculizumab in EHEC-associated HUS. The more recent competing risks method has been shown to be more appropriate in analyzing such situations. Our observations do not strongly support a role for IL-23 in the generation of TH-17 cells in the RA joint, however, they suggest strategies that enhance IL-27 or IFN-gamma might modulate the presence of TH-17 cells in RA. A 43-year-old patient was admitted to our clinic to coronary care unit.

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Long-term prospective cohort studies with required data available should also be analyzed regarding the effect of pasta intake on disease endpoints. AQP4-Ab positive NMOSD patients with a first myelitis attack were retrospectively identified and spinal MRI scans reviewed. G(alpha)q-deficient mice lack metabotropic glutamate receptor-dependent long-term depression but show normal long-term potentiation in the hippocampal CA1 region. Implications of sodium hydrogen exchangers in various brain diseases. To estimate potential public health benefits from ozone (O3) pollution reduction attributable to the use of methyl tertiary-butyl ether (MTBE) in gasoline, O3 dose-response estimates from the biomedical literature were combined with model estimates of O3 reduction. CD26 binds to caveolin-1 in antigen-presenting cells (APC), and that ligation of CD26 by caveolin-1 induces T cell proliferation in a TCR/CD3-dependent manner. Assessment of collagen type II induced arthritis in mice by whole blood chemiluminescence. Detection of differentially expressed genes in human bladder cancer cells using arbitrarily primed PCR of RNA. The objective of the present review is to provide an overview of the various stages of preclinical development, for example, design, molecular modeling studies, synthesis and in vitro/in vivo pharmacological evaluation of alogliptin.

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microRNA-455 targets cullin 3 to activate Nrf2 signaling and protect human osteoblasts from hydrogen peroxide. We showed that salmeterol reduced the growth rate of proliferating cells in a dose- and time-dependent manner (6-48 h). Degradation of polyaromatic hydrocarbons by organic solvent-tolerant bacteria from deep sea. Following application of internal standard, spray solvent and a voltage were applied to the paper before mass spectrometry detection. The applicability of these IAP would be widened drastically by increasing their energy.

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The present study suggests that 10 h/day may be a trigger level of working hours for increased risk of metabolic syndrome among Japanese male workers. Fetal loss rate and associated risk factors after amniocentesis, chorionic villus sampling and fetal blood sampling. Reassessment of 239Pu on planchets from human urine samples at ultra-trace levels using Aridus-ICPSFMS and AMS. Social phobics reported less typical weekly beverage consumption than community subjects. Posterior fossa cyst-ventricle stenting offers the benefits of ease of surgical technique and a low morbidity rate. The influence of positive and negative fluctuations in plasma parameters on the enhancement of ionization oscillations and average current is analyzed. Habitat heterogeneity plays a key role in the dynamics and structures of communities. Neither 1 nor 2 cups of coffee increased ventricular repolarization. Complete fundoplication is not associated with increased dysphagia in patients with abnormal esophageal motility.

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Similarities and dissimilarities of newborn and adolescent rats in the binding capacity of thymic glucocorticoid receptors. Best-corrected visual acuity gained at the end of the RADIANCE trial was sustained over additional 36 months of follow-up. Masquelet technique for the treatment of large dia- and metaphyseal bone defects. Subsequent passaging of the obtained FD-AdV using Bac-B4 as a helper resulted in approximately 100-fold increases of the vector titer at each passage. The low signal intensity seen on T1- and T2-weighted images may have been due to the abundant dense fibrous tissues.

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Flavonoids from Daphne aurantiaca and their inhibitory activities against nitric oxide production. The authors describe the role of sputum cell count and fluid-phase analysis in various conditions, like asthma, COPD, non-asthmatic eosinophilic bronchitis (NAEB) and interstitial lung diseases, as well as in estimating occupational exposure for diagnosing occupational respiratory disorders. The child presented in the neonatal period in respiratory distress with classical features of the syndrome. Participants were then asked a series of questions about their acceptance of the child, stigma that the community might attach to the child, and potential outcomes for the child. Pure UHMWPE, in fact, was modified by the hyaluronic acid that plasticizes the polymer. Calorie counting versus low-fat carbohydrate-rich ad libitum diet. Therefore, some features designed for prehospital use of the VM are actually acting against its use for diagnostic purposes. In brief, enamel organs from 6-month-old porcine third molars were dissociated into single cells and subcultured on 3T3-J2 feeder cell layers. Mesenchymal stromal/stem cells, however, appear to be the leading candidates because of their ability to be sourced from many or all joint tissues. Whereas adjuvant radiotherapy did not seem to affect survival in those patients, co-morbidity significantly did.

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patients with duodenal mucosa damage Marsh I, II and III stages, HLA DQ2/DQ8 haplotype and clinical features suggestive of CD, but negative for CD serology, were defined as seronegative CD patients. In pursuit of these objectives different combinations of LGT genes were substituted into the DEN4 genome but only chimeras containing LGT structural proteins premembrane (preM) and envelope glycoprotein (E) were viable. The objective of this retrospective study was to summarise the clinical manifestations of, and to analyse the incidence and risk factors of, Jarisch-Herxheimer reaction (JHR) during the treatment of children with symptomatic congenital syphilis. It raises awareness among professionals and supports families in the Sudanese and Somalian communities to speak out against the practice. For the fixation of osteotomized MC3 bones, the constructs with plates having rough contact surface were superior to the corresponding constructs with plates having standard smooth contact surfaces in resisting cyclic fatigue under palmarodorsal 4-point bending. Childhood malignant melanomas frequently present as nodular melanomas with Spitzoid features.

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Genotyping of Human Platelet Antigens by BeadChip Microarray Technology. We tested these hypotheses experimentally in the socially monogamous cichlid fish Pelvicachromis taeniatus, in which mate choice is mutual. Achyranthes bidentata polysaccharide enhances immune response in weaned piglets. Objective and subjective image quality was assessed in various anatomic regions and radiation dose was compared. There is a marked risk of acute thrombosis of an ipsilateral arterial bypass graft after TKA that cannot be eliminated by performing the TKA without a tourniquet. The clinical manifestations of patients with tracheobronchial neurofibromas are mostly related to airway obstruction, presenting with cough, wheezing, and dyspnea.

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Development and evaluation of gallium nitride-based thin films for x-ray dosimetry. In this study, we have analyzed the contribution of PACT to these pathways using cells derived from wildtype (WT) and PACT KO mice. Low mean values of FEV1 were observed in workers having high dust exposure, a smoking history and productive cough in comparison to the low dust exposure group, non-smokers and workers without cough symptoms. Entorhinal cortex projection cells to the hippocampal formation in vitro. The atherosclerotic femoral artery may undergo three modes of remodeling in response to plaque formation: compensatory enlargement, failure of compensatory enlargement and paradoxic shrinkage. In this cohort of 110,794 patients, we found that across all vintage groups, NCS was lower in patients who died than in survivors. The importance of standard operating procedures (SOPs) for clinical research centers. To identify the factors influencing participation in a single topic audit initiated by a medical audit advisory group.

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After tumor xenograft in nude mice, tumor growth was subsequently observed. Despite the increased attention for assessing the effectiveness of implementation strategies, most implementation studies provide little or no information on its associated costs. We studied 126 consecutive cases of panic disorder with or without agoraphobia by DSM-III-R criteria, evaluated by relevant structured and semi-structured interviews. Additional structure-activity relationship (SAR) efforts aimed both at increasing potency and improving pharmacokinetic properties led to the discovery of the clinical candidate 63 (ABBV-075/mivebresib), which demonstrates excellent potency in biochemical and cellular assays, advantageous exposures and half-life both in animal models and in humans, and in vivo efficacy in mouse models of cancer progression and inflammation. A study of HLA class I and class II 4-digit allele level in Stevens-Johnson syndrome and toxic epidermal necrolysis. For the breaking bore process, the analysis of the sound record indicated a dominant frequency around 76-77 Hz. There was no correlation between the presence of detrusor-external sphincter dyssynergia and obstructive score on the IPSS or between the presence of detrusor hyperreflexia and irritative score.

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Because cAMP signaling plays a central role in the control of the renin gene expression, we suggested that COUP-TFII may modulate this cAMP effect. These TFs interacted with the promoters of the GLS biosynthetic genes and negatively influenced their expression. During spontaneous healing, the stage of formation of granulation tissue is followed by its replacement with bone and fibrous tissue. CD21 expression was monitored by means of fluorescence intensity, its functional ability to bind to C3d and by quantitative measurement of CD21-antigen in supernatants and cell lysates using an immunoassay. The purpose of this article is to present a focused literature review on the barriers surrounding deactivation of ICDs and to summarize the recommendations of the Heart Rhythm Society Consensus Statement on the management of ICDs in patients nearing end of life or requesting withdrawal of therapy. The central clock dogma contra multiple oscillatory feedback loops. Nivolumab-associated Nephrotic Syndrome in a Patient With Renal Cell Carcinoma: A Case Report. The latter are processed into mature, uncharged tRNAs and are abundantly expressed during both lytic and latent infection. This editorial discusses current knowledge of BiAbs and their applications in targeting activated T cells to cancerous tissues or targeting bone marrow-derived stem cells to myocardial infarction. To carry out meaningful comparisons on results of different research studies on mild cognitive impairment (MCI), it is critical to select an appropriate objective memory test to examine memory deficit.

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Human immunodeficiency virus DNA in urethral secretions in men: association with gonococcal urethritis and CD4 cell depletion. The chronic and ubiquitous gene inactivation obtained with conventional methods has disadvantages, in that it may allow the activation of compensating pathways, making the interpretation of results difficult. RNA interference (RNAi) is a highly specific gene-silencing phenomenon triggered by dsRNA. We estimate functional connectivity using the higher-order statistical dependence, i.e., mutual information among the ICA spatial components, instead of the typically used temporal correlation. Genetic structure of soil population of the fungus Fusarium oxysporum Schlechtend.: Fr.: molecular reidentification of the species and genetic differentiation of isolates using polymerase chain reaction with universal primers (UP-PCR). We describe the interaction between CCDC6 and PP4c and we report the modulation of PP4c enzymatic activity in CCDC6 depleted cells. PAI-1 activity in blood measured spectrophotometrically was significantly elevated as well. However, the total hip arthroplasty provided good clinical results and was associated with long-term survival of the prosthesis. The primary outcome was the composite of readmission or death mometasone furoate inhaler dosage within 30 days after discharge.

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This may be especially important in regions of the world, such as Italy, where use of lamb meat as a weaning food is common during infancy. To evaluate regional anisotropy of lung-airspace orientation by assessing the dependence of helium-3 ((3) He) apparent diffusion coefficient (ADC) values on the direction of diffusion sensitization at two field strengths. Achieving and monitoring adequate depth of anaesthesia is a challenge to the anaesthetist. Moreover, upregulation of miR-181a inhibited CyclinB1 and CyclinD1 expression in NSCLC cells. Microtubules and Grb2 bind to the carboxyl-terminal proline/arginine-rich domain (PRD), whereas phosphoinositides bind to the pleckstrin homology (PH) domain. Preventing mother-to-child transmission of HIV in developing countries: recent developments and ethical implications. Thirteen patients (7 male, 6 female) with non-alcoholic steatohepatitis and 12 (6 male, 6 female) healthy volunteers. Methylenetetrahydrofolate reductase polymorphisms and susceptibility to gastric cancer in Chinese populations: a meta-analysis. DPP4 and NOX1 expression was increased by knockdown of HNF1b and HNF1b directly bound with the promoters of DPP4 and NOX1. Carbonic anhydrase isozyme II immunoreactivity in the mechanoreceptive Ruffini endings of the periodontal ligament in rat incisor.

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Despite the occurrence of some genetic variations in the hypervariable regions of the 18S rDNA in S. Tacrolimus hydrate ointment reduced their eye-scratching behavior. Single-center comparative oncologic outcomes of surgical and percutaneous cryoablation for treatment of renal tumors. Effects of stem bark and leaf extracts of Bridelia ferruginea on rat bladder smooth muscle. extracts in breast and gynaecological cancers: a systematic review of clinical and preclinical research. Meta-analysis was used to estimate a weighted average of the relative proportions of the treatment use, where the weights were the reciprocals of the estimated variances for each study. Late referrals to palliative care units in Japan: nationwide follow-up survey and effects of palliative care team involvement after the Cancer Control Act.

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We investigated the contribution of CSOs in public health research. The root FCR activity, IAA and phenolics accumulation, and also the phenolics secretion were greatly increased by the Fe deficiency treatment. The absorption maxima of both rod and cone visual pigments of the bottlenose dolphin (Tursiops truncatus) are blue-shifted relative to those of terrestrial mammals. QC of storage phosphor digital radiography systems is complex because of the self-corrective nature of the image-processing software used in these machines. Data for each scan were collected in two frames (60 and 120 sec long). Genetic variation in Phoca vitulina (the harbour seal) revealed by DNA fingerprinting and RAPDs. The reaction catalyzed by 6,7-dimethyl-8-ribityllumazine synthase can proceed without enzymatic catalysis under physiological conditions.

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It may be that previous antiandrogen treatment for prostate carcinoma contributed to the fact that our patient developed alpha-fetoprotein-negative and androgen receptor-negative subcutaneous abdominal wall metastasis within a pre-existing lipoma since childhood. Increases in intraabdominal pressure did not result in decreased cardiac output or in a reduction of oxygen transport and consumption in either position. Progression of MM from MGUS is characterized by the selection of MM clones able to inhibit osteoblasts, favoring tumor growth. We performed a retrospective study to compare the effectiveness of TP therapy and CP therapy in optimally debulked patients. In contrast to early postnatal stages, full-length trkC receptors are no longer expressed in adult nerves, which, however, maintain expression of truncated trkC transcripts. Growth in preterm infants fed either a partially hydrolyzed whey or an intact casein/whey preterm infant formula. General practitioner records were linked to identify diagnoses of acne, other triamcinolone cream yeast infection hyperandrogenic conditions, menstrual problems, or consultations for contraceptive management in the preceding year. Observer Variability for Classification of Pulmonary Nodules on Low-Dose CT Images and Its Effect on Nodule Management. Efficiency of photodynamic therapy in the treatment of diffuse facial viral warts in an immunosuppressed patient: towards a gold standard?.

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Pharmacokinetics and clinical efficacy of histochrome in patients with acute myocardial infarction. We report on a displacement metrology setup that provides sub-pm resolution in air. As hypothesized, we found that (1) most affective symptoms and all other subclinical symptoms correlated positively with all PLE, whereas we found only partial associations between negative symptoms and PLE. Esterase D is essential for protection of Neisseria gonorrhoeae against nitrosative stress and for bacterial growth during interaction with cervical epithelial cells. The level of insight is related to cognitive characteristics underlying OCD symptoms, in particular, checking-related uncertainty in checking OCD patients. Olive pomace with medium low cost and high titers of enzymes can be valorized by culture of Actinobacteria to ultram renal dosing produce lignocellulolytic enzymes for industrial applications. However, we observed negative results, that is, no positive signal detected from binding of the NAhR/NArnt heterodimer and XRE site. Chemotherapy should be used to treat metastases due to its indolent clinical course. Parity, use of oxytocin during labour, position at time of giving birth and infant birth weight were associated with second-degree lacerations and episiotomies.

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