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Cymbalta

Cymbalta is a moderately priced drug used to treat depression, anxiety, fibromyalgia, and nerve pain associated with diabetes (diabetic peripheral neuropathy). It is more popular than comparable drugs. As of 2013, it is available in generic and brand versions.

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Also known as: Duloxetine

Description

Cymbalta (duloxetine) is a selective serotonin and norepinephrine reuptake inhibitor antidepressant (SSNRI). Duloxetine affects chemicals in the brain that may be unbalanced in people with depression.

Cymbalta is used to treat major depressive disorder in adults. It is also used to treat general anxiety disorder in adults and children who are at least 7 years old.

Cymbalta is also used in adults to treat nerve pain caused by diabetes (diabetic neuropathy), or chronic muscle or joint pain (such as low back pain and osteoarthritis pain).

Cymbalta is also used to treat fibromyalgia (a chronic pain disorder) in adults and children at least 13 years old.

Dosage

Take Generic Cymbalta with a full glass of water with or without food. It is recommended to take Generic Cymbalta at the same time each day. Do not crush, chew, break, or open a delayed-release capsule. Swallow the tablet whole. If you want to achieve most effective results do not stop using Generic Cymbalta suddenly.

Overdose

If you overdose Generic Cymbalta and you don't feel good you should visit your doctor or health care provider immediately.

Storage

Store at a room temperature between 4 and 30 degrees C (39 and 86 degrees F) away from moisture, light and heat. Throw away the after the expiration date. Keep out of the reach of children.

Side effects

The most common side effects associated with Cymbalta are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.

Contraindications

Do not take Generic Cymbalta if you are allergic to Generic Cymbalta components. Do not take Generic Cymbalta if you're pregnant or you plan to have a baby, or you are a nursing mother. This medication can cause birth defects. Tell your doctor right away if you become pregnant during treatment. Be very careful with Generic Cymbalta if you're pregnant or you plan to have a baby. Do not take Generic Cymbalta if you are breast-feeding. Do not take Generic Cymbalta together with thioridazine (Mellaril), or an MAO inhibitor such as furazolidone (Furoxone), isocarboxazid (Marplan), phenelzine (Nardil), rasagiline (Azilect), selegiline (Eldepryl, Emsam, Zelapar), or tranylcypromine (Parnate). A dangerous drug interaction could occur, leading to serious side effects. You must wait at least 14 days after stopping an MAO inhibitor before you can take Generic Cymbalta. After you stop taking Generic Cymbalta, you must wait at least 5 days before you start taking an MAOI. Generic Cymbalta can be not safety for children and people younger than 18 years old. Do not take Generic Cymbalta if you have any of these conditions:liver or kidney disease, seizures or epilepsy, a bleeding or blood clotting disorder, glaucoma, bipolar disorder (manic depression), a history of drug abuse or suicidal thoughts.Be careful if you drive or do anything that requires you to be alert. Generic Cymbalta may impair your thinking or reactions. Avoid alcohol. It can be dangerous to stop Generic Cymbalta using suddenly.

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Descriptive analysis, diagnostic test, was conducted on 396 pregnant women attending the antenatal clinic between September 2007 and June 2008. Mitogen-activated protein kinase kinase inhibitor PD98059 blocks the trans-activation but not the stabilization or DNA binding ability of hypoxia-inducible factor-1alpha. Role of Th17 cells in the immunopathogenesis of dry eye disease. The reduction in reperfusion injury using drugs has shown mixed results. The purpose of this paper is to explore the readiness of contracted and non-contracted first-level healthcare facilities in Pakistan to deliver quality maternal and neonatal health (MNH) care. Genome engineering: a new approach to gene therapy for neuromuscular disorders. All the tested stems were similar in shape and size, but with some substantial differences. The diagnosis is further confirmed and separated from epidermolysis bullosa acquisita (EBA) by subsequent serologic studies to detect antibodies directed against BP180 and BP230 antigens and characteristic antibody deposition on salt-split skin.

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The laws and rules governing hygiene, safety and medicine in the workplace in Niger were evaluated in this study. Mucoepidermoid carcinoma of the submandibular gland after high-dose radioiodine therapy: case report and review of the literature. A fully automated and efficient method for segmenting ten major structures within the heart in Cardiac CT Angiography data for the purposes of display or cardiac functional analysis. The most effective dose of GHRP-6 was 200 microg/kg and atropine blocked the prokinetic effects of GHRP-6 on GE and IT. Effect of Resveratrol Supplementation on the SNARE Proteins Expression in Adipose Tissue of Stroptozotocin-Nicotinamide Induced Type 2 Diabetic Rats. Long-term exposure to diuretic therapy may be associated with an increased colon cancer-related mortality. The model was based on the Poisson distribution and the Binomial distribution describing parameters for singleplex real-time PCR-based detection of low-level DNA. coli and under conditions which do not closely resemble those found in the human gut. In this paper, we describe some of the more widely used approaches for assessing the anxiolytic activity of known and potential therapeutic agents.

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It may therefore serve as a biomarker of the clinical outcome of lung transplant patients and potentially other patients with airway injury. It was also found that the mobilization of As and the heavy metals was closely correlated, and both were closely correlated to Fe mobilization. By prefilling silicone tubes bridging a 6-mm gap, a length considered limiting for regeneration in the mouse sciatic nerve, with diluted collagen or laminin gels, both matrices allowed for higher levels of recovery and for successful regeneration in a higher proportion of mice than saline solution. In our series, Id1 levels showed an independent prognostic value in patients with adenocarcinoma, regardless of the stage. Moreover these three methods proved to be reliable and gave statistically similar results when combined with cell surface detection of antigens such as CD4, CD8 and CD19 by specific mAbs. On the day of admission, the patient became unresponsive and resuscitative measures were unsuccessful. In the latter culture, phorbol ester induces additional forms of DNA binding activity, whereas L-glutamate fails to do so. Liver function was studied by hepatic scintigraphy with 99mTc-galactosyl serum albumin (GSA) before and after transarterial embolization (TAE) therapy in 16 patients with hepatocellular carcinoma. Automated telephone follow-up after breast cancer: an acceptability and feasibility pilot study. In addition, RA acts as a natural morphogen in neural development.

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The centerline method, using left ventriculograms (LVG), evaluates regional wall motion quantitatively through a comparison of normal data and patient data, and abnormality of wall motion is expressed in units of standard deviation (SD) s from the mean motion in a reference population. Detection of flow in VM was possible in magnitude images or phase-difference images when VENC was set to less than 30 cm/sec. In vitro metabolism of pyriproxyfen by microsomes from susceptible and resistant housefly larvae. Iatrogenic lateral rectus transection secondary to dental implantation surgery. Compared to a long-stay hospital setting, antipsychotic drug use for people with dementia in nursing homes has risen and become less systematic. It is concluded that tonic discharge of cutaneous and muscle nociceptive afferents arising from the foot have specific and opposite effects on Ib inhibitory pathways to ankle extensor motoneurones. Pituitary hormones play an important role in bone growth, modeling, and remodeling. Based on proteomic and spectroscopic investigations we postulate that the differences in the chloroplast structure between the analyzed species are a consequence of quantitative proportions between the individual CP complexes and its arrangement inside membranes.

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Randomised clinical trial comparing Hydrofiber and alginate dressings post-hip replacement. Quality by design principles have been used in developing the strategy. During 7,852 women-years of follow-up, 17 invasive cancers were identified, compared with 11.8 expected, based on age-specific rates from the Cali, Colombia cancer registry. However, the literature contains a number of successful case reports that show surprising changes in the morphology of the condyles. The place of God in synthetic biology: how will the Catholic Church respond?. Among their numerous physiological effects, heat shock proteins (Hsps) are potent immunomodulators, a characteristic reflecting their potential as therapeutic agents and which led to their application in combating infection. To develop and evaluate a figure of merit (FOM) for the measurement of vocal attack time (VAT) for sustained /a/.

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As omics technology is applied to VAP, a paradigm is emerging incorporating simultaneous assessments of microbial populations and their activity, as well as the host response, to personalize prevention and treatment. Roles of ubiquitination in pattern-recognition receptors and type I interferon receptor signaling. This patient underwent toe amputation and has done well for 2.5 years with no evidence of recurrence. While homologous prime-boost immunizations with HCV-specific plasmo-retroVLPs or ex vivo produced VLPs induce a low level of specific antibody responses, optimal combination of plasmo-retroVLPs and VLPs was identified for inducing HCV-specific T-cell and B-cell responses as well as neutralizing antibodies. Response of magnetic properties to metal deposition on urban green in Nanjing, China. To estimate the efficacy and toxicity of typhoid fever vaccines. The effects of a garlic oil chemical compound, propyl-propane thiosulfonate, on ruminal fermentation and fatty acid outflow in a dual-flow continuous culture system.

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