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Cardicon (Nifedipine)
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Cardicon

Cardicon belongs to the group of Calcium Channel Broker (CCB). This medication is used to control chest pain (angina) and hyper tension (high blood pressure). Cardicon was produced by Bayer, a reputed German pharmaceutical company. The initial studies on the drug were undertaken in the year of 1970. This drug is approved by FDA.

Other names for this medication:
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Also known as: Nifedipine

Description

Nifedipine is used alone or together with other medicines to treat severe chest pain (angina) or high blood pressure (hypertension). High blood pressure adds to the workload of the heart and arteries. If it continues for a long time, the heart and arteries may not function properly. This can damage the blood vessels of the brain, heart, and kidneys, resulting in a stroke, heart failure, or kidney failure. High blood pressure may also increase the risk of heart attacks. These problems may be less likely to occur if blood pressure is controlled.

Nifedipine is a calcium channel blocker. It works by affecting the movement of calcium into the cells of the heart and blood vessels. As a result, nifedipine relaxes blood vessels and increases the supply of blood and oxygen to the heart while reducing its workload.

This medicine is available only with your doctor's prescription.

Dosage

This section provides information on the proper use of a number of products that contain nifedipine. It may not be specific to Cardicon PA 20. Please read with care.

In addition to the use of this medicine, treatment for your high blood pressure may include weight control and changes in the types of foods you eat, especially foods high in sodium (salt). Your doctor will tell you which of these are most important for you. You should check with your doctor before changing your diet.

Many patients who have high blood pressure will not notice any signs of the problem. In fact, many may feel normal. It is very important that you take your medicine exactly as directed and that you keep your appointments with your doctor even if you feel well.

Remember that this medicine will not cure your high blood pressure, but it does help control it. You must continue to take it as directed if you expect to lower your blood pressure and keep it down. You may have to take high blood pressure medicine for the rest of your life. If high blood pressure is not treated, it can cause serious problems such as heart failure, blood vessel disease, stroke, or kidney disease.

Swallow the extended release tablet whole. Do not break, crush, or chew it. It is best to take this tablet on an empty stomach.

If you are taking the extended-release tablets, part of the tablet may pass into your stool after your body has absorbed the medicine. This is normal and nothing to worry about.

The dose of this medicine will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of this medicine. If your dose is different, do not change it unless your doctor tells you to do so.

The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.

For treatment of chest pain or high blood pressure: For oral dosage form (capsules): Adults—At first, 10 milligrams (mg) three times a day. Your doctor may increase your dose as needed. Children—Use and dose must be determined by your doctor. For oral dosage form (extended-release tablets): Adults—At first, 30 or 60 milligrams (mg) once a day. Your doctor may increase your dose as needed. However, the dose is usually not more than 90 mg once a day. Children—Use and dose must be determined by your doctor.

Overdose

If you overdose Cardicon and you don't feel good you should visit your doctor or health care provider immediately.

Storage

Store at room temperature between 15 and 25 degrees C (59 and 77 degrees F) away from moisture and heat. Keep container tightly closed. Throw away any unused medicine after the expiration date. Keep out of the reach of children.

Side effects

The most common side effects associated with Cardicon are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.

Contraindications

In deciding to use a medicine, the risks of taking the medicine must be weighed against the good it will do. This is a decision you and your doctor will make. For this medicine, the following should be considered:

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Online preconcentration and two-dimensional separation of cationic compounds via hyphenation of capillary zone electrophoresis with cyclodextrin-modified micellar electrokinetic capillary chromatography. Increased accumulation of mRNA for interleukin (IL)-4, IL-10, and IL-18 was not observed in infected dogs, and mRNA for these cytokines did not correlate with antibody or proliferative responses. An unnecessary laparotomy was avoided in 6.5 per cent of patients and the site of traditional incision was modified in 8.7 per cent. The levels and patterns of mRNA expression of these genes were validated by quantitative RT-PCR analyses. Differences are greatest when studies compare black and white college samples on measures of subclinical eating pathology, like dietary restraint, ideal body shape, and body dissatisfaction. Here, we review the pathogenesis, prevention, and treatment of implant infections due to S. Interfacially-mediated oxygen inhibition for precise and continuous poly(ethylene glycol) diacrylate (PEGDA) particle fabrication. As part of a retrospective study, 76 patients with acute tears of the anterior cruciate ligament who underwent reinsertion and augmentation with the semitendinosus tendon were examined.

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We present results of laboratory sensitivity tests and proof-of-concept evaluations conducted at the US Coast Guard OHMSETT national oil spill response test facility. No other STAT proteins (STAT1, STAT5) were activated by leptin, whereas TNFalpha injection resulted in a dose-dependent phosphorylation of hypothalamic STAT5. Reactivity of dinuclear copper(II) complexes towards melanoma cells: Correlation with its stability, tyrosinase mimicking and nuclease activity. Expression analysis revealed that the catfish complement factor I is constitutively expressed in all tissues and leukocyte cell lines tested, indicating its importance as a regulatory enzyme throughout channel catfish. A recent survey of popular genomic literature estimates that one-fifth of all papers with supplementary gene lists suffer from this issue. Some politico-economic aspects of organ shortage in transplantation medicine. Vascular inflammation is a pivotal factor of a variety of diseases, such as atherosclerosis and tumor progression.

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A molecular phylogeny and classification of Leptochloa (Poaceae: Chloridoideae: Chlorideae) sensu lato and related genera. T3Rs are synthesized as multiple isoforms that display tissue-specific expression patterns and distinct transcriptional properties. The registration is achieved by transforming the local phase bone features, calculated using 3D Log-Gabor filters, to a projection space obtained using 3D Radon transform. Co-administration of delta9-tetrahydrocannabinol almost fully reversed the effect of the antagonist in the week-long regimen. Research is needed on effective methods for integrating HIV prevention for MSM into substance treatment settings, including physician-administered buprenorphine treatment for opiate addiction. Pilin monomers oligomerize due to the interaction of part of their hydrophobic N-terminal alpha-helix. Then we tested eight of the 20 clones producing anti-laminin-1 MAbs to specify their reactivity towards the alpha 1-, beta 1-, and gamma 1-chains and the elastase-cleaved fragments of the laminin-1 molecule. The 316 L stainless steel interface was subjected to two different etching sequences prior to the plasma deposition. Both neoplasms showed aggressive local involvement of the proximal large bowel, which appears to be a predilection site in rhesus monkeys. However, in some smaller areas of these counties, especially in rural areas, the mortality rates of stomach cancer in men were still rather high.

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Invasion of epithelial cells into the adjacent stroma was not evident. It has become common practice to rely on fitted estimates of apparent in vivo metabolic constants (e.g., Vmax and KM) in the parameterization of PBPK models. Effect of lignin preparations and cultivation conditions on the ligninolytic complex of the fungus Pleurotus floridae, the wood white-rot pathogen. However, in many cases, prolonged administration of kinase inhibitors often leads to acquired resistance, and the therapeutic effect is subsequently diminished. In Xenopus, Ednrb2 is expressed by melanoblasts from pre-migration stages and ET3 is expressed around their destinations, suggesting that ET3/Ednrb2 signaling may determine melanophore localization. The aim of the present study was to investigate the anticancer effect of the administration of garlic and lemon aqueous extracts against breast cancer implanted in mice. It usually occurs in the caudal fossa, in the region of the quadrigeminal cistern. Diagnostic accuracy of neurological problems in the emergency department. This paper explores the links between (perceived) environmental risk and community (re) action in an urban industrial neighbourhood in Hamilton, Ontario, Canada.

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Nine men, mean age 55.1 years, mean body mass index 31.2, with a previously confirmed diagnosis of moderate to severe OSAS, were tested on two occasions: immediately before initiation of continuous positive airway pressure (CPAP) treatment and again after at least 4 weeks of continuous nocturnal use of CPAP. Independent Vector Analysis (IVA) for Group fMRI Processing of Subcortical Area. This research focuses on the transient adverse side effects of neurofeedback training via a double-blind, sham/controlled methodology. Changes in Trends and Impact of Testing for Influenza in Infants with Fever under 90 Days of Age. Within the solid solution Cu2ZnGeS4-x Se x , the anion bond alteration parameter changes, showing larger bond lengths for metal-selenium than for metal-sulfur bonds.

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Respiration in the sandy soil was not affected by the addition of TCS, but in clay soil it decreased to TCS at 50 mg/kg of soil. Laparoscopic adrenalectomy has recently been shown to be a safe and effective strategy of treating a variety of benign adrenal tumors. The effect of alvimopan on recovery after laparoscopic segmental colectomy. Clinically relevant predictors of the severity of PES and length of postprocedural hospitalization may exist. Assessing local health department performance in diabetes prevention and control--North Carolina, 2005. The lesion contained fibrotic soft tissue, evidence of a foreign-body giant cell reaction and polyethylene particles, but no metal wear debris, infection, or malignancy. Shear stress modulates the expression of the atheroprotective protein Cx37 in endothelial cells.

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We included adult patients who attended the SMA and completed an immediate pre-post survey. The problem of the accuracy of molecular dynamics simulations is discussed. Biallelic mutations in GPD1 gene in a Chinese boy mainly presented with obesity, insulin resistance, fatty liver, and short stature. Regional differences of physiological functions and cancer susceptibility in the human large intestine. Genome sequence analysis of H5N1 influenza a virus isolated from a Vietnamese in 2007. Based on in vitro findings only, bioactive glasses may be capable of enhancing enamel remineralization in various formulations, compared with other topical remineralizing materials including fluoride, and CPP-ACP. Some factors affecting the airborne survival of bacteria outdoors. A local anaesthetist referent provided information on management of POP. We found several sex differences in clinical characteristics and circumstances of arrest. However, despite the agreement at ambient conditions, the dependence of the helix content on temperature is too weak, a problem shared with other force fields.

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Inhibitors of polyamine biosynthesis have potential clinical uses as antitumor and antiparasitic agents. To evaluate the lesions caused by cadmium poisoning in the digestive tract and the possible effect of the drinking water pH in the initiation of these lesions. The results of recent hematological studies have suggested that, under non-physiological flow conditions, circulating procoagulant proteins activate the coagulation cascade. Randomised trial of personalised computer based information for patients with schizophrenia. In this article, we briefly present the main consequences of malnutrition that affect human growth and development and consider how the DOHaD paradigm, with its evolutionary implications, might contribute to better addressing the challenge of improving nutrition.

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Electron spin resonance measurements showed that binding of PDC-109 to phosphatidylcholine vesicles caused a rigidification of the membrane. Lymphatic filariasis is caused by nematodes Wuchereria bancrofti, Brugia malayi and Brugia timori. Further work is still needed to expand and update the database, as well as compiling data on the relative market share of various products. Statistically no significant differences were found in third molar development between males and females. This study compared the cognitive effects of 1 year of treatment with lamotrigine (LTG) and oxcarbazepine (OXC) in epilepsy patients. The critical role of protein synthesis in regulating lifespan has been evidenced. This paper deals with the theoretical study of the magnetorhelogical properties of dilute suspensions of polymer coils with ferromagnetic nanoparticles adsorbed on the macromolecules. The purpose of this research is to show the demographic structure of the hemodialysis center in Konjic, and also demonstrate the impact of vascular access to the adequacy and the outcome of dialysis treatment.

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Value of MELD and MELD-based indices in surgical risk evaluation of cirrhotic patients: retrospective analysis of 190 cases. Over-fluorination of the fibers at higher reaction pressures of fluorine gas led to the introduction of C-F(2) bonds, which made the surface of the fibers hydrophobic and resulted in a decrease in their swelling potential. We have investigated the structural characteristics of the experimentally observed phase transition of a silver nanowire into a tube under tensile strain. To assess the efficacy of triptorelin 11.25 mg in children with CPP. The mechanism of sonodynamic action in tumor cells is poorly investigated. A possible role of Drosophila CTCF in mitotic bookmarking and maintaining chromatin domains during the cell cycle. After training, the improvement in trajectory shape was only significant in trajectory guidance and, to a lesser extent, visual guidance. The effects of progesterone on nicotine dependence need to be studied further.

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In the meantime, the eradication of echinococcosis succeeded with extermination of dogs and foxes from the island. Further studies are needed to confirm this and to examine the role(s) of other PCP-degrading enzymes in nitrophenol metabolism by this microorganism. Neonatal porcine pancreatic cells were cultured as a monolayer and were transfected with pEBVHGF every other day for a total of three transfections. Nucleotide sequence analysis of COPV showed that it was closely related to human papillomavirus type 1 (HPV 1) and animal PVs associated with cutaneous lesions in rabbit, European elk, deer and cow as we reported previously. In-vivo studies on ovarian insulin-like growth factor I concentrations in human preovulatory follicles and human ovarian circulation. It was found that this characteristic feature is one of the main driving force to realize an ideal V-shaped switching. Concentrations and exposure risks of some metals in facial cosmetics in Nigeria. Does the concentration of alpha 1-proteinase inhibitor reflect the transformation of liver cirrhosis to liver carcinoma?. Statistical evaluation of progression tendencies for treatment results in laryngeal and hypopharyngeal carcinoma. Acute-phase serum amyloid A (A-SAA) is an acute-phase reactant, but is also produced at sites of inflammation and may contribute to vascular inflammation in atherosclerosis.

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To explore the genetic aetiology of fetal posterior fossa abnormalities (PFAs). Furthermore, attention deficits, as measured by a visual tracing task, accounted for impaired arithmetic performance in the new-onset CAE group. Biodegradation: Updating the concepts of control for microbial cleanup in contaminated aquifers. Complete prmt1 gene has only been predicted from two falcon species with few neighboring genes. The process for developing a good research question is described.

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Both incidence and mortality rates for prostate cancer are significantly higher in African American men than in white men. A study of visible defects caused by local cell gap variations in LCD panels. Right gastroepiploic artery was used in 16 cases, and branched radial artery or saphenous vein graft from gastroduodenal artery was used in one case. Angioscopy was performed before, immediately after, and 6 months after stenting to examine the existence of yellow plaque, thrombus, complex plaque, and intramural hemorrhage and the degree of neointimal coverage at 6-month follow-up. (1) For parts of replacement fluid which must be separated (for example, bicarbonate formula), the result is same to the standard, and is predicted and mastered only following the rule of same direction and ratio. To calculate the P(r) curves, a new method based on a specially designed parametric functional form is developed, and implemented in pregxs. Organic and conventional Coffea arabica L.: a comparative study of the chemical composition moduretic brand name and physiological, biochemical and toxicological effects in Wistar rats. Exoenzyme T of Pseudomonas aeruginosa elicits cytotoxicity without interfering with Ras signal transduction.

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Exacerbation of bloody diarrhea as a side effect of mesalamine treatment of active ulcerative colitis. LTR retrotransposons of the Tf1/sushi group from a diversity of vertebrates, including fish, amphibians, and mammals (humans, mice, and others), are described as full-length or partial elements. Microscopy and histology techniques can be applied to morphological study of fungi and bacteria contaminating ancient human osteological remains. Increased cell proliferation and associated expression of PDGFRbeta causing hypercellularity in patellar tendinosis. In most cases it is considered to be a gastrointestinal manifestation of mantle cell nodal lymphoma. In this study, we characterized and compared the structural and morphological properties of three kinds of vertically aligned carbon nanotube (VACNT) arrays from different CVD fabrication methods and performed monotonic compressive tests for each VACNT array. Structure-function studies of human deoxyhypusine synthase: identification of amino acid residues critical for the binding of spermidine and NAD.

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These data support a role for epithelial Nrp1 in the maintenance of normal alveolar structure and suggest amiloride hcl 5 mg side effects that dysregulation of Nrp1 expression may promote epithelial cell death in response to CS exposure, thereby enhancing emphysema development. Cell cycle and apoptosis markers were examined to determine the mechanism of the anti-tumor activity of PTX. The photosensitization mechanisms (Type I and Type 11) of PPa in simple buffer solutions and in buffer solutions containing double-layered DPPC liposomes have been studied using techniques of ESR, spin-trapping, spin-counteraction and laser flash photolysis. However, the stage of the disorder at which these functional alterations occur is unclear. Use of raw ammoniated and glove skin testing preparation sources combined adds to the diagnostic sensitivity. Steady state responses to multiple amplitude-modulated tones: an optimized method to test frequency-specific thresholds in hearing-impaired children and normal-hearing subjects. Electromagnetic Fields Associated with Commercial Solar Photovoltaic Electric Power Generating Facilities. Certain cases that are difficult to approach transvenously are treated with transarterial embolization (TAE) by using liquid materials like such glue.

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For the physician this differentiation represents a clinical and radiological challenge. The deciduous enamel contained significantly more type A carbonate than permanent enamel. We compared the effects of dextrans with a molecular weight of 35 kDa oxidized by chemical (OD(ch)) and radiochemical (OD(r)) methods on oxidative and metabolic functions of peritoneal macrophages from BALB/c mice in vitro and in vivo. In the first case, where one drug is not toxic, the modulation may be evaluated by comparing the inhibition produced by the toxic drug alone and in combination with its modulator. Here, we discuss the progress and impediments the field has faced in using hPSC-derived cardiomyocytes for these in vitro applications, and highlight that rigorous protocol optimisation and standardisation, scalability and automation are remaining obstacles for the generation of pure, mature and clinically relevant hPSC cardiomyocytes. Higher frequency, gamma-band LFP oscillations are usually associated with decision-making, increased attention, and improved reaction times. We analyzed the effect of interventions aimed to reduce treatment delays in our single-center observational series. A child affected by exertional chest pain secondary to gastroesophageal reflux (GER) disease is reported. Ferritin and FasL (CD95L) mediate density dependent apoptosis in primary rat hepatocytes.

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RELEVANCE: Orthotic corrections are commonly prescribed to control excessive foot pronation in patients who experience knee pain. Within the limits of this study, immediate loading of immediately subcrestally placed dental implants in anterior and premolar sites is a reliable treatment option for dental rehabilitation. Recombinant monomeric CD40 ligand for delivering polymer particles to dendritic cells. In situ hybridization histochemistry of vgf mRNA in the rat suprachiasmatic nucleus: co-localization with vasopressin/neurophysin and VIP/PHI. The present overview explores the current state of child and adolescent mental healthcare provision around the globe. Thirty-two patients had a history of previous surgery, 20 patients had a percutaneous nephrostomy, and 12 patients had mild renal impairment. A relapse of mucosal thickening observed in some patients did not influence the graft healing. Recently, a number of procedures have been suggested for this class of models, which are based on first-order Taylor series expansion.

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Several members of the TNFSF are closely associated with inflammatory bowel disease (IBD). Outcome measures included lateral displacement of body center flagyl gel medication of mass (COM) due to the slip and compensatory step width and length after the perturbation. Genome sequence and comparative virulence of raccoonpox virus: the first North American poxvirus sequence. Apical surgery is indicated for successful management of such cases. Classification of data having high dimensionality is usually performed in conjunction with an appropriate feature selection method. The contribution of environmental and genetic factors to plasma lipids is roughly equal. Although he achieved aminimal residual disease negative remission after two cycles of chemotherapy he also developed severe, progressive peripheral and central neurotoxicities. The objective of this study was to examine changes in expression of digestive enzymes, nutrient transporters, and an antimicrobial peptide following an Eimeria praecox challenge of chickens at days 3 and 6 post-infection.

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Serial magnetic resonance (MR) images were obtained for 18 months in the follow-up of a patient with delayed encephalopathy after acute carbon monoxide (CO) poisoning. It has been shown by using the quail/chick chimera system that Hox gene expression in the hindbrain is influenced by positional signals arising from the environment. Medical devices may revolutionize the management of acute ischemic stroke and prevention of recurrent events. Neuroimaging studies implicate putamen as the brain structure involved in the pathophysiology. Ongoing, prospective, open-label, single-center, uncontrolled study.

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We present the first direct experimental evidence for the charge excess in high-energy particle showers and corresponding radio emission predicted nearly 40 years ago by Askaryan. Therefore, the development of a new effective drug or synergist to reduce the prevalence of MDR-TB is urgent to date. Early diagnosis and treatment may prevent progression of neurological changes. Analyses of the interviews have highlighted the impact of disease on eight dimensions: psychological, physical, family, social, couple, sexuality, domestic, professional and economic dimensions. Surveys of allozyme allele frequency and mitochondrial DNA (mtDNA) sequence variation were employed to test historical biogeographical hypotheses on the origin and unique distribution of the synchronized biennial, high-altitude butterflies of the Oeneis chryxus complex in western North America. However, the responsible secondary metabolites in the aerial part of this important plant are largely unknown. The vast majority of participants were able to precisely time their bounces to the vibrations, with no difference in performance between the two groups. GBS natural course during pregnancy is mild and showed quick recovery.

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Mutation of prothrombin at the sodium-binding site caused ATR-phenotypes. Structural RNA modules, sets of ordered non-Watson-Crick base pairs embedded between Watson-Crick pairs, have central roles as architectural organizers and sites of ligand binding in RNA molecules, and are recurrently observed in RNA families throughout the phylogeny. Traditionally, certain acromial morphologies have been thought to contribute to rotator cuff injury by physically decreasing the subacromial space. Networks of protein-protein interactions play key roles in numerous important biological processes in living subjects. In efficacy studies, L-AN was superior to AN in can you overdose a dog on zyrtec reducing colony counts. Based on our findings, efforts to strengthen the family environment may warrant attention. For this study, a phantom consisting of several tubes filled with chemically well-defined liquids was built and measured in PC-CT. In preclinical rat models, a subset of agonist analogs, termed EET-A, EET-B, and EET-C22, are orally active with good pharmacokinetic properties.

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This intervention improved nursing home resident outcomes related to changes in drug use and drug-related expenditure. An off-line setup verification and correction protocol was used and the setup accuracy of the positioning in the bellyboard was determined. The crabs were subsequently parasitized by the rhizocephalan Heterosaccus dollfusi , itself an Erythrean alien. With the increasing awareness of neuron-glial interactions within intact DRG and the use of isolated DRG cells in the study of mechanisms underlying nociception, it will be essential to consider the role played by EP(4) and IP receptor-expressing glial cells when evaluating prostanoid-induced sensitization of DRG neurons. Larger randomized studies are needed to fully evaluate AA against more conventional treatments, and these are planned. The simultaneous occurrence of cardiogenic stroke and acute aortic dissection is rare, and its treatment remains unclear.

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