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Calchan (Nifedipine)

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Calchan is a dihydropyridine calcium channel blocker. Calchan is used to: treat high blood pressure (hypertension), prevent chronic stable angina (chest pain). Calchan was the first calcium channel blocker to be shown to significantly reduce the development of new overt heart failure in patients with coronary artery disease. Excellent blood-pressure control in recent clinical trials has been shown to result in significant protection against stroke. Calchan works by opening up blood vessels in the body to lower blood pressure and improve the supply of blood and oxygen to the heart. Calcium channel blockers do not change the amount of calcium in your blood or bones.

Other names for this medication:
Adefin, Anpect, Aprical, Atenerate, Calcianta, Cordipin, Corinfar, Corotrend, Emaberin, Lemar, Milfadin, Myogard, Nidipine, Nifecap, Nifedate, Nifedel, Nifedical, Nifedip, Nifedipine, Nifezzard, Nipress, Nyefax, Ospocard, Pressolat, Sidalat

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Sovaldi, Mircette, Aldara, Antabuse, Arava, Tizapam, Srivasmine, Domaci, Glyfucan, Azinom, Robiflam, Ciprofloxacinum, Bewormex,

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Also known as: Nifedipine


Nifedipine is used alone or together with other medicines to treat severe chest pain (angina) or high blood pressure (hypertension). High blood pressure adds to the workload of the heart and arteries. If it continues for a long time, the heart and arteries may not function properly. This can damage the blood vessels of the brain, heart, and kidneys, resulting in a stroke, heart failure, or kidney failure. High blood pressure may also increase the risk of heart attacks. These problems may be less likely to occur if blood pressure is controlled.

Nifedipine is a calcium channel blocker. It works by affecting the movement of calcium into the cells of the heart and blood vessels. As a result, nifedipine relaxes blood vessels and increases the supply of blood and oxygen to the heart while reducing its workload.

This medicine is available only with your doctor's prescription.


This section provides information on the proper use of a number of products that contain nifedipine. It may not be specific to Calchan. Please read with care.

In addition to the use of this medicine, treatment for your high blood pressure may include weight control and changes in the types of foods you eat, especially foods high in sodium (salt). Your doctor will tell you which of these are most important for you. You should check with your doctor before changing your diet.

Many patients who have high blood pressure will not notice any signs of the problem. In fact, many may feel normal. It is very important that you take your medicine exactly as directed and that you keep your appointments with your doctor even if you feel well.

Remember that this medicine will not cure your high blood pressure, but it does help control it. You must continue to take it as directed if you expect to lower your blood pressure and keep it down. You may have to take high blood pressure medicine for the rest of your life. If high blood pressure is not treated, it can cause serious problems such as heart failure, blood vessel disease, stroke, or kidney disease.

Swallow the extended release tablet whole. Do not break, crush, or chew it. It is best to take this tablet on an empty stomach.

If you are taking the extended-release tablets, part of the tablet may pass into your stool after your body has absorbed the medicine. This is normal and nothing to worry about.

The dose of this medicine will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of this medicine. If your dose is different, do not change it unless your doctor tells you to do so.

The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.

For treatment of chest pain or high blood pressure: For oral dosage form (capsules): Adults—At first, 10 milligrams (mg) three times a day. Your doctor may increase your dose as needed. Children—Use and dose must be determined by your doctor. For oral dosage form (extended-release tablets): Adults—At first, 30 or 60 milligrams (mg) once a day. Your doctor may increase your dose as needed. However, the dose is usually not more than 90 mg once a day. Children—Use and dose must be determined by your doctor.


If you overdose Calchan and you don't feel good you should visit your doctor or health care provider immediately.


Store at room temperature between 15 and 25 degrees C (59 and 77 degrees F) away from moisture and heat. Keep container tightly closed. Throw away any unused medicine after the expiration date. Keep out of the reach of children.

Side effects

The most common side effects associated with Calchan are:

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Appropriate studies performed to date have not demonstrated geriatric-specific problems that would limit the usefulness of nifedipine in the elderly. However, elderly patients are more likely to have age-related kidney, liver, or heart problems which may require caution and an adjustment in the dose for patients receiving nifedipine.

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To observe the clinical effect of integrative medicinal therapy in treating children Henoch-Schonlein purpura (HSP) and its preventive effect on complicated renal impairment. Current research efforts on the development of selective inhibitors toward certain MMPs gave a vast number of small molecules as potent MMPIs, of which, some of the effective candidates are in their various stages of (pre)clinical trials for the treatment of various diseases such as arthritis and different cancers. Disseminated histoplasmosis accompanied by cutaneous fragility in a cat. For all trials, resilience-focused interventions were effective relative to a control in reducing 4 of 7 outcomes: depressive symptoms, internalizing problems, externalizing problems, and general psychological distress. Lateral wall is a complexed structure out of ligament and capsule with weak tensile strength and tensile rigidity. A 22-year-old man was admitted to our observation with left ventricular thrombus arising after blunt chest trauma occurring during a ski accident one year before.

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Whole-exome sequencing data of 28 members from all 13 families were used for the bioinformatics sequence analysis on the linked regions of these families. With respect to the potential bactericidal activity of CuO NPs on various cariogenic bacteria examined in this study, these NPs could be introduce as a candidate control agent for preventing dental caries or dental infections. The division of foci into bacillary and abacillary is arbitrary. Preliminary study on syndrome differentiation types and acupuncture for whiplash injuries. To examine the conflicting perceptions that health care professionals hold regarding family presence during pediatric resuscitation. Poly-substance users were more likely than alcohol only users to be younger and experience all substance-use related problems studied. Our findings reveal an intimate reciprocal relationship between ErbB4 and NMDA receptors with possible implications for the modulation of cortical microcircuits associated with cognitive deficits in psychiatric disorders. Although this is an improvement for in vitro experiments, further improvements can be made using more realistic UVR sources, e.g. A total of 120 and 287 genes were significantly regulated, respectively. Technical implementation of an EDP based process documentation system for routine use in inpatient medical rehabilitation (RehaProDok).

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Pretreatment by actinomycin D or cycloheximide completely inhibited the up-regulation of I-BABP expression by bile acid. The possible role of iron overload in the deterioration of the PFTs after HSCT was also searched. A novel Ag/AgBr/BiOBr hybrid was prepared by a rational in situ ion exchange reaction between BiOBr hierarchical microspheres and AgNO(3) in ethylene glycol followed by light reduction, which displayed superior visible light driven photocatalytic activities in sterilization of pathogenic organism and degradation of organic dye compared to N-doped P25. The history of polarization microscopy was undertaken by performing a backward search in the scientific literature using Google and internet sites of several Societies for Microscopy and Cell Biology. The two complementation groups cannot be distinguished from each other by clinical, cellular and biochemical criteria except for severe pulmonary involvement which may be characteristic of the second group.

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Letter re: High hypothetical interest in physician-assisted death in multiple sclerosis. Macrophage depletion by a suspension of clodronate liposomes attenuated the plasma corticosterone changes induced by TNF-alpha, but did not affect the sensitization. These differences may reflect distinct environmental conditions and the diverse stressors experienced, as well as physiological and/or behavioural characteristics. Sixteen cases of thyroid papillary carcinoma of columnar cell type were identified from the Endocrine Tumor Registry at the Armed Forces Institute of Pathology and the Washington Hospital Center. Platelet-derived growth factor receptors differentially inform intertumoral and intratumoral heterogeneity. Age is a risk factor for surgery, but coexisting disease is more important than age alone. In this study, we analyzed the correlation of pretreatment Tmax volumes in MR and CT perfusion with clinical outcome after thrombectomy. Results of a diagnostic study of rheumatoid arthritis employing this method are presented. For three-dimensional culture, gingiva-derived stem cells were isolated and seeded into polydimethylsiloxane-based concave micromolds.

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Induction with phenobarbital revealed a different regulation of GST between these species. Molecular cloning and functional analysis of a novel P2 nucleotide receptor. 2) The administration of 5FU with an inhibitor of dihydropyrimidine dehydrogenase (DPD) to minimise the erratic absorption and variable clearance of 5FU: the preparations UFT, S1, and ethinyluracil/5FU contain an oral fluoropyrimidine co-administered orally with inhibitors of this enzyme. Stable bright and vortex solitons in photonic crystal fibers with inhomogeneous defocusing nonlinearity. trifolii has just begun to invade and both species are what class of medication is ventolin still common.

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Although each data source supported the prediction, the authors found the most dramatic changes in clothing choice in the illustrations. The purposes of the study were (1) to compare rotator cuff repair strengths after cyclic loading of 2 bioabsorbable nonsuture-based tack-type anchors, transosseous sutures, and a metal suture-based anchor, and (2) to correlate bone mineral density with mode of failure and cycles to failure. There were large dimensional variations within sizes and discrepancies between the nominal size and actual size. These data demonstrate that the oral cavity of the elderly is inhabited by a diverse array of fungi not limited to typical Candida species and they suggest that the diversity in distribution is associated with health status. Transthyretin could be identified in medium from in vitro pig choroid plexus incubations by size and number of subunits and a very high rate of synthesis and secretion. NTproBNP and BNP levels are reduced in obese subjects, but population-based data comparing the pattern of this relationship in the full spectrum of insulin-resistance mediated conditions, overweight/obesity, metabolic syndrome and diabetes, are limited. The aim of this qualitative study was to explore and gain insights into the effects of myocardial infarction on health-related quality of life. HTA in South Korea has been developed since 1990s, first introduced by academia and institutionalized within the National Health Insurance (NHI).

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We detected the effects of miR155 silencing on ROS production, NO generation, apoptosis and functions of HBMECs at basal and in response to oxidized low density lipoprotein (ox-LDL). We explain them by invoking distinct scenarios for electric-field domain formation, validated by numerical simulations. This therapeutic effect was clearly confirmed how long does 5 mg valium take to work in the Doppler OCT images. Are UK radiologists satisfied with the training and support received in suspected child abuse?. Mini-ureteroneocystostomy is an effective modified extravesical technique for vesicoureteral reflux. Here we combine field data, statistical and mathematical modelling to explore the dynamics of the apparently stable Rhinoderma darwinii-Batrachochytrium dendrobatidis (Bd) system. The questionnaire was marked by two of the authors and observations recorded by another author. Penetration of oxidative and reductive reactions in the field of clinical chemistry.

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For the concept of vertical ridge augmentation to enable dental implant placement, there are clinical and histological data supporting its potential use. In November half of the animals of both species were put to a three-week fast. Resting and exercise hemodynamics in pulmonary arterial hypertension. Taken together, MPS may be therapeutically superior to MP in IBD treatment. Significant statistical differences were found between the following risk factors: number of sexual partners, age at first intercourse, age at first pregnancy. The safety profile of SIT should be evaluated using international guidelines and terminology, and needs to include high-quality surveillance data. We used the calcium reporter cameleon to track in vivo calcium fluxes in the axotomized neuron. We found that ECM treatment reduced lesion volume and improved neurobehavioral function. Characteristics and financial performance of a pediatric faculty inpatient attending service: a resource-based relative value scale analysis. Influence of acupuncture and moxibustion on QOL of the elderly living in nursing home and care house.

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