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Bitorva (Ezetimibe)
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Bitorva

Bitorva is an add-on medication to diet to improve cholesterol levels. This medication is an alternative option to statins. Bitorva is a cholesterol-lowering medication. It reduces the amount of cholesterol that is absorbed by the body, which helps lower total cholesterol and "bad" cholesterol (called LDL) in your blood.

Other names for this medication:
Atofast, Atolife, Atorvik, Avascare, Bitorva, Etimibe, Ezedoc, Ezentia, Ezerem, Ezetib, Ezetimiba, Ezetimibe, Ezetrol, Ezevas, Ezibloc, Eziwa, Ezzicad, Filet, Imbibe, Lipezet, Liponorm, Mactor, Orvas, Razel, Redustat, Statix, Storvas, Tonact, Visvas, Zeteze, Zetica, Zetimax, Zetivas, Zient, Zivast

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Also known as: Ezetimibe

Description

Bitorva (ezetimibe) reduces the level of total cholesterol and LDL (bad) cholesterol in the blood.

Bitorva is used to treat high cholesterol in people who cannot control their cholesterol levels by diet and exercise alone.

Bitorva works to reduce the amount of cholesterol your body absorbs. You should stay on a cholesterol-lowering diet while taking this medicine.

Bitorva is sometimes given together with other cholesterol-lowering medications.

Dosage

Usual Adult Dose of Bitorva for Hyperlipidemia:

10 mg orally once a day Uses: -For use as monotherapy or in combination with an HMG-CoA reductase inhibitor (statin) as an adjunct to diet to reduce elevated total cholesterol (total-C), low-density lipoprotein cholesterol (LDL-C), apolipoprotein B (Apo B), and non-high-density lipoprotein cholesterol (non-HDL-C) in patients with primary (heterozygous familial and non-familial) hyperlipidemia -For use as combination therapy with fenofibrate as an adjunct to diet to reduce elevated total-C, LDL-C, Apo B, and non-HDL-C in patients with mixed hyperlipidemia -As an adjunct to diet to reduce elevated sitosterol and campesterol levels in patients with homozygous familial sitosterolemia -For use as combination therapy with atorvastatin or simvastatin to reduce elevated total-C and LDL-C levels in patients with homozygous familial hypercholesterolemia, as an adjunct to other lipid-lowering treatments (e.g., LDL apheresis) or if such treatments are unavailable

Usual Adult Dose of Bitorva for Homozygous Familial Hypercholesterolemia:

10 mg orally once a day Uses: -For use as monotherapy or in combination with an HMG-CoA reductase inhibitor (statin) as an adjunct to diet to reduce elevated total cholesterol (total-C), low-density lipoprotein cholesterol (LDL-C), apolipoprotein B (Apo B), and non-high-density lipoprotein cholesterol (non-HDL-C) in patients with primary (heterozygous familial and non-familial) hyperlipidemia -For use as combination therapy with fenofibrate as an adjunct to diet to reduce elevated total-C, LDL-C, Apo B, and non-HDL-C in patients with mixed hyperlipidemia -As an adjunct to diet to reduce elevated sitosterol and campesterol levels in patients with homozygous familial sitosterolemia -For use as combination therapy with atorvastatin or simvastatin to reduce elevated total-C and LDL-C levels in patients with homozygous familial hypercholesterolemia, as an adjunct to other lipid-lowering treatments (e.g., LDL apheresis) or if such treatments are unavailable

Usual Adult Dose of Bitorva for Sitosterolemia:

10 mg orally once a day Uses: -For use as monotherapy or in combination with an HMG-CoA reductase inhibitor (statin) as an adjunct to diet to reduce elevated total cholesterol (total-C), low-density lipoprotein cholesterol (LDL-C), apolipoprotein B (Apo B), and non-high-density lipoprotein cholesterol (non-HDL-C) in patients with primary (heterozygous familial and non-familial) hyperlipidemia -For use as combination therapy with fenofibrate as an adjunct to diet to reduce elevated total-C, LDL-C, Apo B, and non-HDL-C in patients with mixed hyperlipidemia -As an adjunct to diet to reduce elevated sitosterol and campesterol levels in patients with homozygous familial sitosterolemia -For use as combination therapy with atorvastatin or simvastatin to reduce elevated total-C and LDL-C levels in patients with homozygous familial hypercholesterolemia, as an adjunct to other lipid-lowering treatments (e.g., LDL apheresis) or if such treatments are unavailable

Usual Pediatric Dose for Hyperlipidemia:

10 years or older: 10 mg orally once a day Uses: -For use as monotherapy or in combination with a statin as an adjunct to diet to reduce elevated total-C, LDL-C, Apo B, and non-HDL-C in patients with primary (heterozygous familial and non-familial) hyperlipidemia -For use as combination therapy with a fenofibrate as an adjunct to diet to reduce elevated total-C, LDL-C, Apo B, and non-HDL-C in patients with mixed hyperlipidemia -As an adjunct to diet to reduce elevated sitosterol and campesterol levels in patients with homozygous familial sitosterolemia -For use as combination therapy with atorvastatin or simvastatin for the reduction of elevated total-C and LDL-C in patients with homozygous familial hypercholesterolemia, as an adjunct to other lipid-lowering treatments (e.g., LDL apheresis) or if such treatments are unavailable

Usual Pediatric Dose for Homozygous Familial Hypercholesterolemia:

10 years or older: 10 mg orally once a day Uses: -For use as monotherapy or in combination with a statin as an adjunct to diet to reduce elevated total-C, LDL-C, Apo B, and non-HDL-C in patients with primary (heterozygous familial and non-familial) hyperlipidemia -For use as combination therapy with a fenofibrate as an adjunct to diet to reduce elevated total-C, LDL-C, Apo B, and non-HDL-C in patients with mixed hyperlipidemia -As an adjunct to diet to reduce elevated sitosterol and campesterol levels in patients with homozygous familial sitosterolemia -For use as combination therapy with atorvastatin or simvastatin for the reduction of elevated total-C and LDL-C in patients with homozygous familial hypercholesterolemia, as an adjunct to other lipid-lowering treatments (e.g., LDL apheresis) or if such treatments are unavailable

Usual Pediatric Dose for Sitosterolemia:

10 years or older: 10 mg orally once a day Uses: -For use as monotherapy or in combination with a statin as an adjunct to diet to reduce elevated total-C, LDL-C, Apo B, and non-HDL-C in patients with primary (heterozygous familial and non-familial) hyperlipidemia -For use as combination therapy with a fenofibrate as an adjunct to diet to reduce elevated total-C, LDL-C, Apo B, and non-HDL-C in patients with mixed hyperlipidemia -As an adjunct to diet to reduce elevated sitosterol and campesterol levels in patients with homozygous familial sitosterolemia -For use as combination therapy with atorvastatin or simvastatin for the reduction of elevated total-C and LDL-C in patients with homozygous familial hypercholesterolemia, as an adjunct to other lipid-lowering treatments (e.g., LDL apheresis) or if such treatments are unavailable

Detailed Bitorva dosage information

Overdose

Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.

Storage

Store at room temperature between 15 and 30 degrees C (59 and 86 degrees F) away from moisture and heat. Keep container tightly closed. Throw away any unused medicine after the expiration date. Keep out of the reach of children.

Side effects

The most common side effects associated with Bitorva are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.

Contraindications

You should not use Bitorva if you are allergic to ezetimibe, or if you have:

moderate to severe liver disease.

Bitorva is not approved for use by anyone younger than 10 years old.

You should not use Bitorva with a "statin" cholesterol medicine (Zocor, Lipitor, Crestor, and others) if:

you have active liver disease; you are pregnant; or you are breastfeeding a baby.

Statin cholesterol medications can cause the breakdown of muscle tissue, which can lead to kidney failure. This happens more often in women, in older adults, or people who have kidney disease or poorly controlled hypothyroidism (underactive thyroid).

To make sure Bitorva is safe for you, tell your doctor if you have:

liver disease; kidney disease; or unexplained muscle pain or weakness.

Tell your doctor if you are pregnant or breastfeeding.

Use effective birth control to prevent pregnancy while you are using Bitorva with a statin medicine. Tell your doctor if you plan to become pregnant.

Do not breastfeed if you take Bitorva with a statin medicine.

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In our pilot study, we measured serum chemerin levels by enzyme-linked immunosorbent assay in six severe heterozygous FH patients before and after their first LDL apheresis treatments using the technique of direct adsorption of lipoproteins (DALI). To investigate the effect of having a contract for self-referral to inpatient treatment (SRIT) in patients with severe mental disorders. Effects of plant intraspecific diversity across three trophic levels: Underlying mechanisms and plant traits. All six patients presented respiratory distress and feeding problem early in life. Universal stress protein Rv2624c alters abundance of arginine and enhances intracellular survival by ATP binding in mycobacteria. Thus, in this model lisuride and 8-OH-DPAT behave as 5-HT antagonists.

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This article provides a framework for a systematic video-based running biomechanics analysis plan based on the current evidence on running injuries, using 2-dimensional (2D) video and readily available tools. There was no evidence of improved control of posture as a mechanism underlying this result. Therapeutic approaches of adenocarcinoma of lipitor 20 mg tablet generic the exocrine pancreas. farinae-specific IgE was not changed during the pollen season in these patients. We show that the decline in lung TRM is determined by an imbalance between apoptosis and lung recruitment and conversion to TRM of circulating memory cells. Potentially modifiable behavioural factors explained the greatest part of this association with a leading contribution of adiposity, body mass index, and physical activity. These genes are predicted to function in pathways consistent with myocardial injury.

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