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Bionil (Glibenclamide)
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Bionil

Bionil belongs to a class of medicines called biguanides. It works by lowering glucose production in the liver, delaying the absorption of sugar from the intestines, and increasing the body's sensitivity to insulin.

Other names for this medication:
Afdiex, Aviglen, Betanase, Bionil, Daonil, Diabnil, Diolin, Duotrol, Eumet, Giclamide, Glibson, Glifil, Glitrac, Gluconil, Glucosafe, Glucotrac, Glybid, Glybonil, Glyboral, Glybovin, Glycurb, Glycurub, Iscept, Metclam, Sugnil, Symet, Triglucored, Triglycomet

Similar Products:
Maxalt, Aceon, Zebeta, Levothroid, Danocrine, Kamagra, Imitrex, Zeftra, Digoregen, Agoxin, Torsid, Romipraz, Velrid,

Also known as: Glibenclamide

Description

Bionil is used along with diet and exercise, and sometimes with other medications, to treat type 2 diabetes (condition in which the body does not use insulin normally and, therefore, cannot control the amount of sugar in the blood). Bionil is in a class of medications called sulfonylureas. Bionil lowers blood sugar by causing the pancreas to produce insulin (a natural substance that is needed to break down sugar in the body) and helping the body use insulin efficiently. This medication will only help lower blood sugar in people whose bodies produce insulin naturally. Bionil is not used to treat type 1 diabetes (condition in which the body does not produce insulin and, therefore, cannot control the amount of sugar in the blood) or diabetic ketoacidosis (a serious condition that may occur if high blood sugar is not treated).

Over time, people who have diabetes and high blood sugar can develop serious or life-threatening complications, including heart disease, stroke, kidney problems, nerve damage, and eye problems. Taking medication(s), making lifestyle changes (e.g., diet, exercise, quitting smoking), and regularly checking your blood sugar may help to manage your diabetes and improve your health. This therapy may also decrease your chances of having a heart attack, stroke, or other diabetes-related complications such as kidney failure, nerve damage (numb, cold legs or feet; decreased sexual ability in men and women), eye problems, including changes or loss of vision, or gum disease. Your doctor and other healthcare providers will talk to you about the best way to manage your diabetes.

Dosage

The dose of this medicine will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of this medicine. If your dose is different, do not change it unless your doctor tells you to do so.

The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.

  • For type 2 diabetes:
    • For oral dosage form (tablets):
      • Adults—At first, 2.5 to 5 milligrams (mg) once a day taken with breakfast or the first main meal. Your doctor may adjust your dose if needed. However, the dose is usually not more than 20 mg per day.
      • Children—Use and dose must be determined by your doctor.

Overdose

Seek emergency medical attention or call the Poison Help line at 1-800-222-1222. A Bionil overdose can cause life-threatening hypoglycemia.

Symptoms of severe hypoglycemia include extreme weakness, nausea, tremors, sweating, confusion, trouble speaking, fast heartbeats, or seizure.

Storage

Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing.

Keep out of the reach of children.

Do not keep outdated medicine or medicine no longer needed.

Ask your healthcare professional how you should dispose of any medicine you do not use.

Side effects

The most common side effects associated with Bionil are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.

Contraindications

In deciding to use a medicine, the risks of taking the medicine must be weighed against the good it will do. This is a decision you and your doctor will make. For Bionil, micronized, the following should be considered:

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The effects of measurement site and ambient temperature on body temperature values in healthy older adults: a cross-sectional comparative study. Pitavastatin, a statin recently approved in the United States, has a potential benefit of reduced risk of cytochrome P450 (CYP)-mediated drug-drug interaction due to minimal metabolism by the CYP system. Spectrin and DRP had more positive reactions in immature myotubes, compared with those of dystrophin. Studies show that 5-methoxypsoralen and 8-methoxypsoralen reduced birth rates in rats. In our experience, concurrent LD-FRT and chemotherapy was well tolerated.

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Rats were initially trained to report about a recent event (food versus no food) and separately searched for food where there was no expectation of being asked about the presence of food. Cyclophilin and the regulation of symbiosis in Aiptasia pallida. In all cases, the postoperative angiographic results corresponded to the intraoperative ICG video angiographic findings. Significant advances have been made in the molecular biology of C. Effects of Pulsed Versus Conventional Versus Combined Radiofrequency for the Treatment of Trigeminal Neuralgia: A Prospective Study.

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