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Bifosa (Alendronate)

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Bifosa is a bisphosphonate (bis FOS fo nayt) medicine that alters bone formation and breakdown in the body. This can slow bone loss and may help prevent bone fractures. Bifosa is a potent inhibitor of bone resorption and is most commonly used in the treatment and prevention of osteoporosis.

Other names for this medication:
Alant, Alendix, Alendronate, Alenost, Bifosa, Denfos, Osteofos, Ostogee, Poronil, Ralenost, Restofos, Zophost

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Microzide, Persantine, Lopid, Abhigra, Pepcid, Dilantin, Exelon, Citilat, Clindamycinum, Emvate, Ventiphylline, Alphapress, Clopigrel, Bronkotab, Bicalutamide, Bisoprololum,

Also known as: Alendronate


Bifosa (alendronate) is a bisphosphonate (bis FOS fo nayt) medicine that alters bone formation and breakdown in the body. This can slow bone loss and may help prevent bone fractures.

Bifosa is used in women to treat or prevent osteoporosis caused by menopause and in men and women to treat osteoporosis caused by taking steroids.

Bifosa is also used to increase bone mass in men who have osteoporosis, and to treat Paget's disease of bone in men and women.


Take Bifosa exactly as prescribed by your doctor. Bifosa is taken either once daily or once per week. Follow all directions on your prescription label. Do not take this medicine in larger or smaller amounts or for longer than recommended.

Take Bifosa first thing in the morning, at least 30 minutes before you eat or drink anything or take any other medicine. If you take this medicine only once per week, take it on the same day each week and always first thing in the morning.

Take with a full glass (6 to 8 ounces) of plain water. Do not use coffee, tea, soda, juice, or mineral water. Do not eat or drink anything other than plain water.

Do not crush, chew, or suck on an Bifosa tablet. Swallow the tablet whole.

For at least 30 minutes after taking Bifosa:

Do not lie down or recline. Do not take any other medicine including vitamins, calcium, or antacids.

Pay special attention to your dental hygiene while taking Bifosa. Brush and floss your teeth regularly. If you need to have any dental work (especially surgery), tell the dentist ahead of time that you are using alendronate.

Bifosa is only part of a complete program of treatment that may also include diet changes, exercise, bone mineral density testing, and taking calcium and vitamin supplements. Follow your doctor's instructions very closely.

Store at room temperature away from moisture and heat.

Your doctor will determine how long to treat you with this medicine. Bifosa is often given for only 3 to 5 years.

Detailed Bifosa dosage information


Drink a full glass of milk and seek emergency medical attention or call the Poison Help line at 1-800-222-1222. Do not make yourself vomit and do not lie down.


Store at room temperature between 15 and 30 degrees C (59 and 86 degrees F) away from moisture and heat. Throw away any unused medicine after the expiration date. Keep out of the reach of children.

Side effects

The most common side effects associated with Bifosa are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.


Avoid taking any other medicines for at least 30 minutes after taking Bifosa. This includes vitamins, calcium, and antacids. Some medicines can make it harder for your body to absorb alendronate.

Avoid smoking, or try to quit. Smoking can reduce your bone mineral density, making fractures more likely.

Avoid drinking large amounts of alcohol. Heavy drinking can also cause bone loss.

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Antilymphocyte Globulin (ALG) in Clinical Organ Transplantation. Up-regulation of cyclin D is a crucial event for entry into the G1 phase of the cell cycle, and links mitogenic signalling to cell proliferation. Here, the authors show that two DMAbs targeting Pseudomonas aeruginosa proteins confer protection against lethal pneumonia in mice. Vascular endothelial growth factor, platelet endothelial cell adhesion molecule-1 and vascular cell adhesion molecule-1 in the follicular fluid of patients undergoing IVF. Neurocognitive decline although could be one of the key symptoms domains in neurosyphilis. They can even reduce the excess mortality of chronic rheumatoid inflammatory diseases. The unique hybridization of static anatomic restriction and dynamic absorptive bypass lends a duality to the beneficial effects of Roux-en-Y gastric bypass. Fps1 functions as a homotetramer, and control of its channel activity in response to hyperosmotic shock involves a redundant pair of fungus-specific regulators, Rgc1 and Rgc2 (regulators of the glycerol channel), and the mitogen-activatd protein kinase (MAPK) Hog1 (high-osmolarity glycerol response). Hitherto, subjective nasal symptom scores have been the most often used outcome parameter, but in standardized modern trials objective parameters are preferred. A prospectively designed algorithm was applied retrospectively to a cohort of 758 patients with clinically localized or locally advanced prostate cancer.

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Viral growth, intracellular lipid accumulation and gene expression profiles were determined in human mesenchymal stem cells (hMSCs) infected with Ad-36 or Ad-2. Elevated homocysteine levels with weight loss after Lap-Band surgery: higher folate and vitamin B12 levels required to maintain homocysteine level. We were the first center in India to use teleradiology on a regular basis. The potential application of GIIb/IIIa targeted therapy might theortically be expanded by the new class of oral GP IIb/IIIa antagonists. We have demonstrated that it is possible to use a medial approach for open reduction of the congenitally dislocated hip in combination with tenodesis of the ligamentum teres to the anteromedial joint capsule. The radiation dose for the different radiopharmaceuticals used to study transplant organ function ranges between 0.1 and 5.3 mSv which is comparable to X-ray procedures with the exception of 201Tl and 111In-antimyosin. Intravascular lymphoma with conus medullaris syndrome followed by encephalopathy. We have shown EspF to interact with the endocytic regulators sorting nexin 9 (SNX9) and N-WASP via non-exclusive binding sites.

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In recent years, mRNA-based vaccines have emerged to be a great alternative to DNA-based vaccines due to the safety of not inserting into host genome. We established close proximity of the proposed candidate genes which are located within a 1.2 Mb interval. Impact of distal aortic and visceral perfusion on liver function during thoracoabdominal and descending thoracic aortic repair. Exosomes are small vesicles that mediate cell-cell communication. Professional athletes experience physiological modifications during competitions and over a season: the risk of sports anaemia is high. Faster onset is desirable to reduce the anguish caused by delusions and hallucinations and to protect patients and others from the consequences of poor judgment associated with psychotic exacerbation. In cases where intracranial sources were quite focal, surface EEG sources were localized with accuracy, even in medial occipital lobe structures. As the 104th Congress with a Republican majority tackles health care policy, initiatives with a plausible chance of legislative approval include the mandating of universal access to insurance, community rating, maternal and child care coverage, and tort reform. Audit: Monitoring of side effects using GASS (Glasgow Antipsychotic Side-Effect Scale).

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Biaryl-based macrocyclic and polymeric chiral (salophen)Ni(II) complexes: synthesis and spectroscopic study. The Kaplan-Meier survival rate and prognostic factors of events were analyzed using log-rank tests and uni- and multivariate Cox model-based analyses. Structured responses were obtained for living arrangement, marital status, social relationships, and supports. 7-ketocholesterol (7-KC) differs from cholesterol by a functional ketone group at C7. Prognostic value of Ki 67/MIB1 automated and quantitative immunolabelling in primary operable ultram dosing adults breast carcinomas. sativa seemed to be diphyletic, since strong similarity was observed between O. The restricted requirement of Numb during neural development in the mouse suggests that in some neuronal lineages, Notch signaling may be regulated independently of Numb. The photodecomposition in natural sunlight of two neonicotinoid insecticides, thiamethoxam and thiacloprid, was investigated in wastewater, aqueous extracts of sewage sludge and in aqueous surfactant solutions, which are abundant in wastewater.

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Paracoccidioidomycosis: an uncommon localization in the scrotum. We present a patient with two asymptomatic bronchogenic cysts found at a distance from the tracheobronchial tree. Unfortunately, traditional 3D methods for smoothing and cluster-based statistical inference cannot be used for voxel-based analysis of these measures, since the local neighbourhood for smoothing and cluster formation can be ambiguous when adjacent voxels may have different numbers of fixels, or ill-defined when they belong to different tracts. Expression of angiotensin II type 1 (AT1) and angiotensin II type 2 (AT2) receptors in human granulosa-lutein (GL) cells: correlation with what drugs interact with robaxin infertility diagnoses. Tear film thickness over the inferior paracentral cornea was measured using laser illumination and a complementary metal-oxide-semiconductor (CMOS) camera.

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Although regular alcohol consumption seems to reduce the incidence of atherothrombotic cardiovascular events, excessive alcohol intake increases the risk of many medical and psychosocial problems. Uranium isotope compositions of the basaltic angrite meteorites and the chronological implications for the early Solar System. Lithium is licensed for the treatment of bipolar disorders and also discussed in relation to neuroprotective properties. PLASTER METHODS OF TREATING MUSCLE CONTRACTURES FOLLOWING WOUNDS. Allelotyping of 10p combined with fluorescence in situ hybridization in these hybrid cells suggested that a prostate tumor suppressor gene was located within a fragment of approximately 1.2 Mb flanked by D10S1172 and D10S226 on 10p15.1. These rates in each group were compared with the chi(2) test and the Kaplan-Meier method. In addition, the increase in uPA induced by IL-4 could counterbalance the direct interaction of uPAR with vitronectin. Imaging ion flux and ion homeostasis in blood stage malaria parasites. Although D-penicillamine, L-cysteine and GSH did not increase the Hg removal in the long-term experiment other antidotal effects were seen. When the mice were primed with the H1N1 or H3N2 vaccines, this did not affect the booster response to the H5N1 vaccine.

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No routine antibiotic treatment for patients with diverticulitis. The renal vasodilatation in septic acute kidney injury may be due to nitric oxide derived from the endothelial and neural isoforms of nitric oxide synthase, but their blockade did not restore renal function. Angiogenic sprout formation from equally sized adipose tissue fragments, but not from aorta rings, was greatly increased by obesity and by TZD treatment in vivo. The mutant lacking PC-PLC was 20-fold less virulent in mice and was defective in cell-to-cell spread but had no measurable defect in escape from a primary vacuole. Effect of amantadine on weight gain during olanzapine treatment. Here we studied the tyrosine phosphorylation of STAT (signal transducer and activator of transcription) proteins in the hypothalamus of normal rats after iv injection of recombinant murine leptin or TNFalpha or coinjection of both cytokines. Assessing heterogeneity in the relationship between wheat yield and Fusarium head blight intensity using random-coefficient mixed models. Parental war involvement was associated with negative psychosocial sequels for male children.

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pylori LPS on spontaneous PMNL apoptosis, and mechanisms by which this H. In general, SLDR inhibition was greatest in the cell lines with the highest SLDR capacity while there was no such correlation with PLDR. The cytotoxic activities of 1-4 against the HepG2 cell line were evaluated. The primary outcomes of interest were survival rates, membrane exposure rates, bone gain/defect reduction, and vertical bone loss at follow-up. An asymmetric sensory polyneuropathy related to thiamine deficiency from a gluten-free diet. Numerical simulations with two-dimensional (2D) finite-difference time-domain (FDTD) method demonstrate that, even for flat LHM lens of material losses to the order as that reported in some LHM microwave experiments and simulations, the refocusing of backscattered microwave will yield a sub-wavelength lateral resolution and remarkable enhancement of the backscattered microwave, which will benefit the detection and imaging of small target. Our continuing experience with allografts has led us to the firm conclusion that there is a clear place for allografts in the ligamentous reconstruction of the unstable knee. Supplementation of PPC had marked lipid-lowering effects and PBMC gene expression profiles seemed to reflect nutrition-related metabolic changes.

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