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Bestradiol (Estradiol)

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Bestradiol is a female hormone (estrogen). It is used by women to help reduce vaginal symptoms of menopause (such as vaginal dryness/burning/itching). These symptoms are caused by the body making less estrogen. Bestradiol is available under different brand names.

Other names for this medication:
Bestradiol, Conjugase, Divigel, Edval, Espauz, Estogen, Estraderm, Estradiol, Estrofem, Evafem, Evalon, Evaride, Menocare, Mixogen, Oestrogel, Premarin, Progynon, Progynova, Sandrena

Similar Products:
Cardura, Allegra, Evista, Periactin, Cycrin, Xeloda, Celebrex, Avodart, Hytrin, Coljoy, Cosvate, Epsoval, Tenoric, Kinzalplus, Optycin, Fazine, Paxib, Omnitel, Combutol,

Also known as: Estradiol


Estradiol is a form of estrogen, a female sex hormone that regulates many processes in the body.

Some estradiol products placed directly into the vagina are used for "local" treatment of vaginal menopause symptoms (such as dryness, burning, and irritation). Other vaginal estradiol products are used for treating vaginal menopause symptoms and symptoms that affect other parts of the body (such as hot flashes). This type of vaginal estradiol has "systemic" effects, meaning that it can affect parts of the body other than where the medicine is directly applied.

This medication guide provides information about Bestradiol Vaginal for local treatment of vaginal symptoms of menopause (such as dryness, itching, irritation, and pain during sexual intercourse).


Take Bestradiol exactly as it was prescribed for you. Follow all directions on your prescription label. Do not take this medicine in larger amounts or for longer than recommended.

Estradiol may increase your risk of developing a condition that may lead to uterine cancer. Call your doctor at once if you have any unusual vaginal bleeding while using this medicine.

Your doctor should check your progress on a regular basis (every 3 to 6 months) to determine whether you should continue this treatment. Self-examine your breasts for lumps on a monthly basis and have a mammogram every year while using Bestradiol.

If you need major surgery or will be on long-term bed rest, you may need to stop using this medicine for a short time. Any doctor or surgeon who treats you should know that you are using Bestradiol.

Store at room temperature away from moisture, heat, and light. Keep the bottle tightly closed when not in use.

Detailed Bestradiol dosage information


Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.


Store at room temperature between 20 and 25 degrees C (68 and 77 degrees F) away from moisture, light and heat. Keep container tightly closed. Throw away any unused medicine after the expiration date. Keep out of the reach of children.

Side effects

The most common side effects associated with Bestradiol are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.


Avoid smoking. It can greatly increase your risk of blood clots, stroke, or heart attack while using Bestradiol.

Grapefruit and grapefruit juice may interact with Bestradiol and lead to unwanted side effects. Avoid the use of grapefruit products.

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GABA-dependent firing of glutamate-evoked action potentials at AMPA/kainate receptors in developing hypothalamic neurons. Diagnosis of metastatic carcinoid in mesenteric lymph node by fine needle aspiration cytology. Ultrastructural immunolocalization by electron microscopy revealed that the IgE reactivity was confined to the cuticular surface of the infective (L3) larvae. These results strongly suggested that a combination therapy with a low dose of CY with an inoculation of allogeneic lymphocytes augmented an induction of specific cytotoxic T lymphocytes in the tumor-bearing recipient mice. We analyzed the database of 2752 DM patients obtained from the Korean National Diabetes Program (KNDP). Thus, in isolated rat neonatal cardiomyocytes expressing GHR, GH induces hypertrophy and causes alterations in cellular metabolic profile in the absence of demonstrable changes in IGF-1 mRNA, suggesting that these effects may be independent of IGF-1. Behavioral studies seem useful for evaluating the function of the spinal cord, especially for assessing the injured system in the spinal cord. Alcoholic fermentation by wild-type Hansenula polymorpha and Saccharomyces cerevisiae versus recombinant strains with an elevated level of intracellular glutathione. The two sets of antibodies gave slightly different results that might be ascribed to the different epitopes recognized by the antisera. A gastric volvulus can be safely treated using laparoscopic techniques.

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