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Besquil (Alprazolam)

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Besquil is commonly used to treat anxiety and panic disorders. It falls into a category of medications called benzodiazepines. They are known to affect the central nervous system components and produce a calming effect, thus decreasing brain activity.

Other names for this medication:
Aldep, Almac, Alpranex, Alprop, Alprotame, Alprozam, Alzam, Alzex, Alzoft, Alzoset, Ansilumirm, Azicalm, Benzolam, Betapax, Calmef, Calmtec, Depoxit, Depsolam, Dipra, Esteem, Finezol, Fludep, Luzarn, Nokzok, Norex, Nucalm, Pacyl, Plaxid, Prozolam, Restyl, Riolam, Sanprazole, Selamb, Serex, Sertakem, Sertamax, Somaspas, Tagat, Tenlax, Trustin, Tryzo, Xanti, Zamitol, Zolam, Zolent, Zolran, Zoltweet

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Also known as: Alprazolam


Alprazolam is used to relieve symptoms of anxiety, including anxiety caused by depression. It is also used to treat panic disorder in some patients.

Alprazolam is a benzodiazepine. Benzodiazepines belong to the group of medicines called central nervous system (CNS) depressants, which are medicines that slow down the nervous system.

This medicine is available only with your doctor's prescription.


This section provides information on the proper use of a number of products that contain alprazolam. It may not be specific to Besquil XR. Please read with care.

Take this medicine only as directed by your doctor. Do not take more of it, do not take it more often, and do not take it for a longer time than your doctor ordered. If too much of this medicine is used for a long time, it may become habit-forming (causing mental or physical dependence) or cause an overdose.

This medicine should come with a Medication Guide. Read and follow the instructions carefully. Ask your doctor if you have any questions.

Swallow the extended-release tablet or tablet whole with a full glass of water. Do not break, crush, or chew it.

If you are using the orally disintegrating tablet, make sure your hands are dry before you handle the tablet. Do not remove the tablets from the bottle until you are ready to take it. Place the tablet immediately on the top of your tongue. It should melt quickly and be swallowed with saliva.

If you are using the oral liquid, measure the dose with a marked measuring spoon, oral syringe, or medicine cup.

Do not eat grapefruit or drink grapefruit juice while you are using this medicine.

The dose of this medicine will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of this medicine. If your dose is different, do not change it unless your doctor tells you to do so.

The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.

For anxiety: For oral dosage forms (solution, tablets, or orally disintegrating tablets): Adults—At first, 0.25 to 0.5 milligram (mg) 3 times a day. Your doctor may increase your dose as needed. However, the dose is usually not more than 4 mg per day. Older adults—At first, 0.25 mg 2 or 3 times a day. Your doctor may increase your dose as needed. Children—Use and dose must be determined by your doctor. For panic disorder: For oral dosage form (extended-release tablets): Adults—At first, 0.5 to 1 milligram (mg) taken in the morning once a day. Your doctor may increase your dose as needed. However, the dose is usually not more than 10 mg per day. Older adults—At first, 0.5 mg taken in the morning once a day. Your doctor may increase your dose as needed. Children—Use and dose must be determined by your doctor. For oral dosage forms (solution, tablets, or orally disintegrating tablets): Adults—At first, 0.5 milligram (mg) 3 times a day. Your doctor may increase your dose as needed. However, the dose is usually not more than 10 mg per day. Older adults—At first, 0.25 mg 2 or 3 times a day. Your doctor may increase your dose as needed. Children—Use and dose must be determined by your doctor.


Seek emergency medical attention or call the Poison Help line at 1-800-222-1222. An overdose of alprazolam can be fatal.

Overdose symptoms may include extreme drowsiness, confusion, muscle weakness, loss of balance or coordination, feeling light-headed, and fainting.


Store at room temperature away from light and moisture. Do not store in the bathroom. Keep all medications away from children and pets.Do not flush medications down the toilet or pour them into a drain unless instructed to do so. Properly discard this product when it is expired or no longer needed. Consult your pharmacist or local waste disposal company for more details.

Side effects

The most common side effects associated with Besquil are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.


Appropriate studies performed to date have not demonstrated geriatric-specific problems that would limit the usefulness of alprazolam in the elderly. However, elderly patients are more likely to have unwanted effects (eg, severe drowsiness, dizziness, confusion, clumsiness, or unsteadiness) and kidney, liver, or lung problems, which may require caution and an adjustment in the dose for patients receiving this medicine.

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Adrenal steroidogenesis in rats bred for susceptibility and resistance to the hypertensive effect of salt. The patient status was complicated by a systemic thrombosis including coronary graft occlusion and central vein thrombosis. The latter has been previously found to occur with significantly higher frequency in probands of families with familial hypoalpha. The formation of lithium dendrites induces the notorious safety issue and poor cycling life of energy storage devices, such as lithium-sulfur and lithium-air batteries. Cardiac tamponade due to apixaban therapy in patient with unknown pericardial hemangioma. The article is mainly directed to the investigation and analysis of frozen-hydrated sections in the low dose cryo-transmission electron microscopy (TEM) and cryo-energy filtered TEM (EFTEM). We show that transgenic tobacco and cotton plants constitutively expressing tomato Ve1 exhibit enhanced resistance against Verticillium wilt in an Ave1-dependent manner.

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Genetic dosage and position effect of small supernumerary marker chromosome (sSMC) in human sperm nuclei in infertile male patient. Public value at risk from Phytophthora ramorum and Phytophthora kernoviae spread in England and Wales. The study determined the health workers willingness to participate in EVD vaccine clinical trials and receive EVD vaccine. Quantitative real-time polymerase chain reaction (qRT-PCR) and immunohistochemical staining were employed to measure Wnt5b mRNA and protein expressions in two groups of HBV-related HCC patients (100 cases in each) selected from a cohort of 289 cases with HBV-related HCC using simple random sampling method. CRC Cell proliferation, colony formation, cell apoptosis and cell invasion assays were performed to explore the effect of NaBt, miR-203 and NEDD9 on HT-29 and Caco-2 cell lines. Rats were trained to respond for sucrose pellets under a PR schedule. Employing quantum chemical calculations, we explore how they can be used in molecular design to address the sulfur atom in a methionine residue in a previously neglected, directed manner. We present an analytical procedure to compute the first derivatives of the propagation constants with respect to several structural parameters in photonic crystal fibers (PCFs). In cytochalasin B-treated, degranulating cells 30,000 to 50,000 receptors were up-regulated within a minute.

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Extraction of Total Available Carbohydrates from Grass and Legume Tissue. Application of Long-Range Surface Plasmon Resonance for ABO Blood Typing. It was of some value in the exploration of patent digestive haemorrhage or chronic diarrhoea, but not of abdominal pain. The Trier Social Stress Test for Groups (TSST-G) was executed with 302 male recruits during their first week of Swiss Army basic training. Providing self-collected sampling for HPV testing was more effective than sending reminder letters to increase screening coverage in under-screened women. Expert commentary: To date there are no exclusive guidelines for the peripartum management of bipolar disorder.

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Topical capsaicin in the treatment of painful diabetic neuropathy. We seek to identify what factors were decisive in the selection processes that resulted in the closure of visible disputes (visible in or across the assessment reports) for both cases. We evaluated the associations between birth month and 5 cardiovascular disease-related outcomes in an independent registry of 8,346 patients from Ontario, Canada in 1977-2014. Relation of fibroblast growth factor-23 and cardiovascular calcification in end-stage kidney disease patients on regular hemodialysis. In previous studies we showed that exposure to soiled male bedding augmented immediate early gene immunoreactivity in neurons of the basal zone of the vomeronasal organ, an effect that depended on gender and sex steroid expression. The Department of Health (DH) is piloting personal health budgets across 20 sites in England, including pilot studies of people eligible for NHS continuing health care.

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Impact of p16 Alterations and Pretreatment Anemia on Toxicity in Head and Neck Cancer Patients Undergoing Definitive Radiochemotherapy. Lymphocytes from the normal donor responded to GH administration with a significant increase of the mean number of silver positive NOs per cell as well as lymphocytes from the growth hormone deficient patient (P less than 0.001). Pubovesical ligaments, rather than the commonly reported puboprostatic ligaments, were observed attaching the bladder-prostate unit to the pubis. We found that Ebp1-p42 significantly enhanced autophosphorylation of PKR, while Ebp1-p48 isoform strongly inhibited it. Extracting the effects of gene flow, divergent selection and reproductive isolation from such modifying factors presents a major challenge to speciation genomics. We calculated four measures of non-buprenorphine opioid use: (1) number of prescriptions, (2) quantity dispensed, (3) days of supply and (4) total morphine milligram equivalents (MME) before, during and after the first treatment episode. 3,5-diiodothyronine (3,5-T2) reduces blood glucose independently of insulin sensitization in obese mice.

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Although a variety of nanoparticles (NPs) have been used for drug delivery applications, their surfaces are immediately covered by plasma protein corona upon systemic administration. It also considers the key evidence-based strategies towards preventing diabetic foot ulcer. Instead, we consider the unconditional bias of estimators of the treatment effect for marker-positive patients. 7,12-dimethylbenz(a)anthracene and hepatic neoplasia in regenerating rat liver. Patients with diabetes have a worse postoperative course and longer length of hospital stay after surgery. Diagnosis of the former is both simpler and more rewarding, whereas atheromatous lesions of the renal artery may be secondary to essential hypertension. Among men, trait impulsivity and fluctuations in negative emotion predicted binge eating. We hypothesized that ghrelin/obestatin imbalance played a role in the pathogenesis. Precise biomechanical knowledge of individual components of the MCL is critical for proper MCL release during TKA. Content validity of the Valued Life Activities scale was excellent, concurrent validity strong, and the internal consistency excellent.

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A comparison of inhibition of steady state, new transport, and exchange fluxes of amino acids in brain slices. The study concluded safety of total clipless laparoscopic cholecystectomy using a harmonic scalpel in Child A and B type cirrhotic patients, who presented with complicated gallstones. Previous studies have documented the phasic pulmonary vascular response to infused Escherichia coli endotoxin in unanesthetized sheep. Influence of synthesis parameters on hyaluronic acid hydrogels intended as nerve conduits. For each county, they counted the number of issuers offering stand-alone dental plans (SADPs) and medical plans with embedded pediatric dental benefits. Differential Effects of Linagliptin on the Function of Human Islets Isolated from Non-diabetic and Diabetic Donors. trachomatis strains resistant to acylated sulfonamides were isolated by serial passage of a wild-type strain in the presence of low compound concentrations. Others, like the antisense oligomers, are such a new technology that there are many hurdles to be overcome as the agents move from the laboratory to the clinic. Analysis of human sodium iodide symporter gene expression in extrathyroidal tissues and cloning of its complementary deoxyribonucleic acids from salivary gland, mammary gland, and gastric mucosa.

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Glutamine-dependent amidotransferases have been known for more than 30 years. Using accountability mechanisms more intentionally: A framework and its implications for training professional psychologists. These results suggest that interferon alfa enhancement of adoptive immunotherapy was mediated by its effect on tumor cells. Water electrolysis is a key technology for the replacement of fossil fuels by environmentally friendly alternatives, but state-of-the-art water oxidation catalysts rely on rare elements such as Pt groups and other noble metals. The prevalence of micronuclei was significantly decreased in the e-cigarette smoker group. The guidelines of the French and foreign scientific societies were also consulted. The affordability of the device will save hospital administrators and the country great cost while still being effective. Physical Load Affects Perceptual-Cognitive Performance of Skilled Athletes: a Systematic Review. It is characterized by the presence of three additional longitudinal carinae inserted between the elevated suture and the three normal costae commonly found on each elytron of the previously known species of Akiyamaia. indocin gout dose Statistical studies on relation between numbers of patients with streptococcal infectious disease and meteorological data (5th report).

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Lipid oxidation is a process ubiquitous in life, but the direct and comprehensive analysis of oxidized lipids has been limited by available analytical methods. Synthesis and evaluation of N-aryl pyrrolidinones as novel anti-HIV-1 agents. Two epitopes in CFP-10 were characterized, and the MHC class II alleles restricting them were determined. Somatization in Post-Concussion Syndrome: A Retrospective Study. An excellent hydrophilic surface was obtained after the alkali heating treatment while the hydrophilicity decreased to some degree after the self-assembly of APTMS, the surface hydrophilicity was gradually improved again after the immobilization of PEG, fibronectin or fibronectin/heparin rosuvastatin 10 mg and fenofibrate 160 mg brand name complex. CCK-8, its C-terminal fragment and those Thy-1-antigen peptides which contained immunoactive amino acids at C- or N-terminus or both, stimulated IgM-plaque forming cells (PFC) in animals.

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To determine effects of progesterone (P4) treatment on luteinizing hormone (LH) secretion in turkey hens, two trials were conducted. Conditional tenomodulin overexpression favors tenogenic lineage differentiation of transgenic mouse derived cells. As gro induction was specifically associated with the antimitogenic action of IL-1, we studied the effect of the cytokine on gro gene expression in other types of cells. Reverse transcription-polymerase chain reactions (RT-PCR) were conducted using RNA extracted from lymph nodes and skin from TSk2 mice and from normal mice, with an oligonucleotide primer library specific for the variable region of the TCR (beta) chain. Obstructive sleep apnea (OSA) and chronic obstructive pulmonary disease (COPD) both cause an inflammatory response and hypoxia. We report the results of infection experiments with Australian classical strain 06/95 and variant strain 02/95 in SPF chickens. Combined extra-intradural temporal rhizotomy for the treatment of trigeminal neuralgia.

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