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Bakton (Trimethoprim)
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Bakton

Bakton is a combination of two synthetic (man-made) antibiotics, sulfamethoxazole and trimethoprim. Both drugs reduce the ability of some bacteria to utilize folic acid for growing. Sulfamethoxazole is an anti-bacterial sulfonamide, a sulfa drug.

Other names for this medication:
Bacterol, Bactricid, Baktimol, Bioprim, Broncoflam, Cotripharm, Diseptyl, Dosulfin, Globaxol, Irgagen, Kanprim, Metoxiprim, Netocur, Novotrim, Noxaprim, Sigaprim, Sitrim, Sulbron, Sulfamethoxazolum, Sulfatrim, Suprasulf, Supreme, Triforam, Trimetoger, Trimoks, Trisulfose, Tritenk

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Also known as: Trimethoprim

Description

Sulfamethoxazole and trimethoprim combination is used to treat infections such as urinary tract infections, middle ear infections (otitis media), bronchitis, traveler's diarrhea, and shigellosis (bacillary dysentery). This medicine is also used to prevent or treat Pneumocystis jiroveci pneumonia or Pneumocystis carinii pneumonia (PCP), a very serious kind of pneumonia. This type of pneumonia occurs more commonly in patients whose immune systems are not working normally, such as cancer patients, transplant patients, and patients with acquired immune deficiency syndrome (AIDS).

Sulfamethoxazole and trimethoprim combination is an antibiotic. It works by eliminating the bacteria that cause many kinds of infections. This medicine will not work for colds, flu, or other virus infections.

This medicine is available only with your doctor's prescription.

Dosage

Prescribing Bakton (sulfamethoxazole and trimethoprim) tablets in the absence of a proven or strongly suspected bacterial infection or a prophylactic indication is unlikely to provide benefit to the patient and increases the risk of the development of drug-resistant bacteria.

Bakton should be given with caution to patients with impaired renal or hepatic function, to those with possible folate deficiency (e.g., the elderly, chronic alcoholics, patients receiving anticonvulsant therapy, patients with malabsorption syndrome, and patients in malnutrition states) and to those with severe allergies or bronchial asthma.

Hematological changes indicative of folic acid deficiency may occur in elderly patients or in patients with preexisting folic acid deficiency or kidney failure. These effects are reversible by folinic acid therapy.

Overdose

If overdose is suspected, contact a poison control center or emergency room immediately. US residents can call their local poison control center at 1-800-222-1222. Canada residents can call a provincial poison control center. Symptoms of overdose may include: severe nausea/vomiting/diarrhea, severe dizziness or drowsiness, mental/mood changes.

Storage

Store at room temperature away from light and moisture. Do not store in the bathroom. Keep all medications away from children and pets.

Do not flush medications down the toilet or pour them into a drain unless instructed to do so. Properly discard this product when it is expired or no longer needed. Consult your pharmacist or local waste disposal company.

Side effects

The most common side effects associated with Bakton are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.

Contraindications

Bakton is contraindicated in patients with a known hypersensitivity to trimethoprim or sulfonamides, in patients with a history of drug-induced immune thrombocytopenia with use of trimethoprim and/or sulfonamides, and in patients with documented megaloblastic anemia due to folate deficiency.

Bakton is contraindicated in pediatric patients less than 2 months of age. Bakton is also contraindicated in patients with marked hepatic damage or with severe renal insufficiency when renal function status cannot be monitored.

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A novel anti-inflammatory role for spleen-derived interleukin-10 in obesity-induced inflammation in white adipose tissue and liver. Despite prophylactic inhaled corticosteroid treatment, no clinical or radiographic improvement was observed and widespread bronchial destruction developed very rapidly. Similar, but less pronounced changes have been found in gastric juice of patients with gastric precancerosis. Volterra series modelling and compensation of non-linear distortions caused by susceptibility difference artefacts related to the presence of ferromagnetic implants in magnetic resonance imaging. Severe Mycoplasma pneumoniae-associated mucositis treated with immunoglobulins. Moreover, the robot significantly shortened the learning curve of this difficult task. On the other hand, hybridization analyses showed that the smvA gene is present in all the S. AFLP genome scans suggest divergent selection on colour patterning in allopatric colour morphs of a cichlid fish.

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