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Bactiver (Trimethoprim)

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Bactiver is an effective combination antibiotic; however, it may not be suitable for those with kidney or liver disease or folate deficiency. The risk of side effects may be higher in the elderly.

Other names for this medication:
Actrim, Adrenol, Anitrim, Assepium, Astrim, Avlotrin, Bacin, Bacta, Bactrizol, Baktar, Biotrim, Bitrim, Colizole, Cosat, Cotribene, Cotrimstada, Epitrim, Esbesul, Exazol, Infatrim, Neotrim, Primadex, Qiftrim, Resprim, Roxtrim, Suftrex, Sulbron, Sumetrolim, Tabrol, Trisulfose, Trisulin, Trizole, Urobactrim, Zoltrim

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Also known as: Trimethoprim


Generic Bactiver is taken to fight against ear infections, urinary tract infections, bronchitis, traveler's diarrhea, Pneumocystis carinii pneumonia. Generic Bactiver works by killing or slowing the growth of sensitive bacteria. Generic Bactiver can't be given to children younger than 2 months old. Bactiver is also known as Co-trimoxazole, Septra, Ciplin, Septrin. Generic names of Generic Bactiver are Sulfamethoxazole, Trimethoprim. Brand names of Generic Bactiver are Bactiver, Bactiver DS, Septra, Septra DS, Sulfatrim Pediatric.


This section provides information on the proper use of a number of products that contain sulfamethoxazole and trimethoprim. It may not be specific to Bactiver DS. Please read with care.

Take this medicine exactly as directed by your doctor. Do not take more of it, do not take it more often, and do not take it for a longer time than your doctor ordered. To do so may increase the chance of side effects.

Sulfamethoxazole and trimethoprim combination is best taken with a full glass (8 ounces) of water. Several additional glasses of water should be taken every day, unless otherwise directed by your doctor. Drinking extra water will help to prevent some unwanted effects (eg, crystals in the urine). .

For patients taking the oral liquid, use a specially marked measuring spoon or other device to measure each dose accurately. The average household teaspoon may not hold the right amount of liquid.

To help clear up your infection completely, keep using this medicine for the full time of treatment, even if you begin to feel better after a few days. If you stop taking this medicine too soon, your symptoms may return.

The dose of this medicine will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of this medicine. If your dose is different, do not change it unless your doctor tells you to do so.

The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.

For oral dosage forms (liquid or tablets): For treatment of bacterial infections: Adults—1 tablet (DS tablet) of 800 milligrams (mg) of sulfamethoxazole and 160 mg of trimethoprim, 2 tablets of 400 mg of sulfamethoxazole and 80 mg of trimethoprim, or 4 teaspoonfuls or 20 milliliters (mL) of oral liquid every 12 hours for 10 to 14 days. Your doctor may adjust this dose if needed. Children 2 months of age and older—Dose is based on body weight and must be determined by your doctor. The usual dose is 40 milligrams (mg) per kilogram of body weight of sulfamethoxazole and 8 milligrams (mg) per kilogram of body weight of trimethoprim, given in two divided doses every 12 hours for 10 days. Weighing 40 kilograms (kg)—4 teaspoonfuls (20 mL) of oral liquid or 2 tablets (or 1 DS tablet) 2 times a day for 10 days. Weighing 30 kg—3 teaspoonfuls (15 mL) of oral liquid or 1 ½ tablet 2 times a day for 10 days. Weighing 20 kg—2 teaspoonfuls (10 mL) of oral liquid or 1 tablet 2 times a day for 10 days. Weighing 10 kg—1 teaspoonful (5 mL) of oral liquid 2 times a day for 10 days. Children younger than 2 months of age—Use is not recommended. For treatment of bronchitis: Adults—1 tablet (DS tablet) of 800 milligrams (mg) of sulfamethoxazole and 160 mg of trimethoprim, 2 tablets of 400 mg of sulfamethoxazole and 80 mg of trimethoprim, or 4 teaspoonfuls or 20 milliliters (mL) of oral liquid every 12 hours for 14 days. Children 2 months of age and older—Use and dose must be determined by your doctor. Children younger than 2 months of age—Use is not recommended. For treatment of Pneumocystis jiroveci pneumonia or Pneumocystis carinii pneumonia (PCP): Adults and children 2 months of age and older—Dose is based on body weight and must be determined by your doctor. The usual dose is 75 to 100 milligrams (mg) per kilogram of body weight of sulfamethoxazole and 15 to 20 milligrams (mg) per kilogram of body weight of trimethoprim each day, given in equally divided doses every 6 hours for 14 to 21 days. Weighing 80 kilograms (kg)—10 teaspoonfuls (50 milliliters (mL)) or 5 tablets (or 2 ½ DS tablets) 4 times a day for 14 to 21 days. Weighing 64 kg—8 teaspoonfuls (40 mL) or 4 tablets (or 2 DS tablets) 4 times a day for 14 to 21 days. Weighing 48 kg—6 teaspoonfuls (30 mL) or 3 tablets (or 1 ½ DS tablets) 4 times a day for 14 to 21 days. Weighing 40 kg—5 teaspoonfuls (25 mL) or 2 ½ tablets 4 times a day for 14 to 21 days. Weighing 32 kg—4 teaspoonfuls (20 mL) or 2 tablets (or 1 DS tablet) 4 times a day for 14 to 21 days. Weighing 24 kg—3 teaspoonfuls (15 mL) or 1 ½ tablets 4 times a day for 14 to 21 days. Weighing 16 kg—2 teaspoonfuls (10 mL) or 1 tablet 4 times a day for 14 to 21 days. Weighing 8 kg—1 teaspoonful (5 mL) 4 times a day for 14 to 21 days. Children younger than 2 months of age—Use is not recommended. For prevention of Pneumocystis jiroveci pneumonia or Pneumocystis carinii pneumonia (PCP): Adults—800 milligrams (mg) of sulfamethoxazole and 160 mg of trimethoprim once a day. Children 2 months of age and older—Dose is based on body size and must be determined by your doctor. The usual dose is 750 mg of sulfamethoxazole and 150 mg of trimethoprim per square meter (m[2]) of body surface each day. This is given in equally divided doses two times a day for 3 days a week on consecutive days (eg, Monday, Tuesday, Wednesday). However, the dose is usually not more than 1600 mg of sulfamethoxazole and 320 mg of trimethoprim per day. Children younger than 2 months of age—Use is not recommended. For treatment of traveler's diarrhea: Adults—1 tablet (DS tablet) of 800 milligrams (mg) of sulfamethoxazole and 160 mg of trimethoprim, 2 tablets of 400 mg of sulfamethoxazole and 80 mg of trimethoprim, or 4 teaspoonfuls or 20 milliliters (mL) of oral liquid every 12 hours for 5 days. Children 2 months of age and older—Use and dose must be determined by your doctor. Children younger than 2 months of age—Use is not recommended.


Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.

Overdose symptoms may include loss of appetite, vomiting, fever, blood in your urine, yellowing of your skin or eyes, confusion, or loss of consciousness.


Consult the product instructions and your pharmacist for storage details. Keep all medications away from children and pets. Do not flush medications down the toilet or pour them into a drain unless instructed to do so. Properly discard this product when it is expired or no longer needed. Consult your pharmacist or local waste disposal company.

Side effects

The most common side effects associated with Bactiver are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.


You should not use Bactiver if you are allergic to sulfamethoxazole or trimethoprim, or if you have:

severe liver disease; kidney disease that is not being treated or monitored; anemia (low red blood cells) caused by folic acid deficiency; a history of low blood platelets after taking trimethoprim or any sulfa drug; or if you take dofetilide (Tikosyn).

Do not use Bactiver if you are pregnant. This medicine could harm the unborn baby or cause birth defects. Use effective birth control, and tell your doctor if you are pregnant or become pregnant.

Do not breastfeed while using this medicine.

This medicine should not be given to a child younger than 2 months old.

To make sure Bactiver is safe for you, tell your doctor if you have:

kidney or liver disease; a folate (folic acid) deficiency; asthma or severe allergies; a thyroid disorder; malnourishment; alcoholism; high levels of potassium in your blood; porphyria, or glucose-6-phosphate dehydrogenase (G6PD) deficiency; or if you use a blood thinner (such as warfarin) and you have routine "INR" or prothrombin time tests.

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Compliance towards dispensed medication labelling standards: a cross-sectional study in the state of Penang, Malaysia. Optimal positioning of temporary epicardial atrial pacing leads after cardiac surgery. Effects of endothelin-1 and nitric oxide on proliferation of cultured guinea pig bronchial smooth muscle cells. Expanded repertoire of AAV vector serotypes mediate unique patterns of transduction in mouse brain. The heterophylly, evolved from linear to toothed-ovate shape, showed the significant difference in cuticle thickness, stomata densities, and sizes. Localized detection of action potential-induced presynaptic calcium transients at a Xenopus neuromuscular junction. This study evaluated several planning strategies to determine which method best provides adequate tumor coverage, minimal normal tissue irradiation, and simplicity of use. Agreement between chosen therapy and isolated pathogen susceptibility was compared before and after education. The role of the gut sweet taste receptor in regulating GLP-1, PYY, and CCK release in humans.

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Comparative study of permeability of derivatives of gamma-aminobutyric and gamma-hydroxybutyric acids through hemato-encephalic barrier. In the adjuvant setting, the optimal duration of imatinib treatment remains unknown. Low temperature near-field luminescence studies of localized and delocalized excitons in quantum wires. Erythromycin for women with pPROM is associated with a range of health benefits for the neonate, and thus a probable reduction in childhood disability. Bacterial diversity in persistent periapical lesions on root-filled teeth. Beyond utilitarianism: a method for analyzing competing ethical principles in a decision analysis of liver transplantation. However, in hypoxia and hypercapnia, there are many controversies ethambutol brand about the regulation of nitric oxide on cerebral blood vessels.

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Another adenovirus vector expressing mutant p27(kip1) (Adp27-mt), which inhibited degradation by the ubiquitin-proteasome system, showed increased protein stability and caused a stronger induction of apoptosis. The aim of this study was to evaluate whether the influence of different beverages may be used to help in the ingestion of an aspirin tablet on the pharmacokinetic parameters of this drug. Entry of B cell antigen receptor and antigen into class lipitor 40 mg uses II peptide-loading compartment is independent of receptor cross-linking. Altogether, the data presented in this paper suggest that before unfolding the protein explores a distribution of states which is centered around compact states at denaturant concentrations below 2 M in H(2)O, and then shifts to less structured states by increasing denaturant concentrations. The diagnostic criterion for T4 disease using CT alone was tumor strongly displacing or deforming adjacent organs. For several years, oral candidiasis has been treated effectively with azole drugs, the one most frequently used is fluconazole.

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Kinetic studies indicate that the mechanism for the variation in HDL levels associated with various pathophysiologic states includes changes in the fractional catabolic rate (FCR) and/or the synthesis rate of HDL and its major proteins apolipoprotein (apo) A-I and apo A-II. Identification, assessment and prioritization of ecotoxicological risks on the scale of a territory: Application to WWTP discharges in a geographical area located in northeast Lyon, France. This study explored the effects of nursing intervention on the BSE intention, BSE frequency and BSE accuracy among beauticians as community target groups. A protocol for adherence to EAU guidelines for antibiotic prophylaxis for all urologic procedures was introduced in January 2011. Bisphosphonate acts on osteoclasts independent of ruffled borders in osteosclerotic (oc/oc) mice. About 114 women with preeclampsia, 31 with early onset (EOP) and 83 with late onset preeclampsia (LOP), and 100 normal pregnant controls were included. In order to better understand the behaviour of these methods in the PPD, we compare the performance of traditional approaches (LOCF, CC) and theoretically sound techniques (MI, ML), under various MAR mechanisms. These data suggest an important role for psychosocial factors in the etiology of low prenatal weight gain among white women but show no such role for black women. Early and delayed consolidation chemotherapy significantly improves the outcome of children with intermediate risk acute lymphoblastic leukemia. The literature shows that hardware removal rates after the fixation of maxillofacial fractures with miniplates are not insignificant.

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We find that the variations of commonly used complexity measures with provigil modafinil 200mg pills time are either similar or reciprocal. The humoral response to DNA vaccination of mice with two important Fasciola antigens has been investigated. In the first of two long-term studies, study A, Sprague-Dawley rats were exposed by inhalation to 0, 5, 10 or 20 ppm NVP (6 hr/day, 5 days/wk) for 24 months. gingivalis and a cell line of extravillous trophoblasts (HTR-8) derived from the human placenta. Rats injected with ORX-A into the BNST displayed greater anxiety-like measures in the social interaction and elevated plus maze tests compared to vehicle treated controls. Because BC (rather than co-morbidities) is the main cause of death in patients with muscle-invasive disease, aggressive BC-directed therapies in these patients, when feasible, are justified. Spheroids were treated with a panel of small molecule drugs including MK2206, RAD001, BEZ235, MLN0128 and MEK162, alone and in combination with irradiation.

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Other strategies allowed higher percentages of leaks to migrate between monitoring wells. Hence, ethnic RhD antigen background must be considered when developing transfusion and obstetric strategies. Hypoxia-driven increase of extracellular adenosine in local tissue microenvironments of inflamed and cancerous tissues plays a critical role in the regulation of tissue destruction by activated immune cells. In the influenza season 2009/10, the new pandemic influenza A/H1N1 clearly predominated in Central and Eastern Slovakia. Renal biopsy revealed diffuse proliferative glomerulonephritis (DPGN) with depositions of immunoglobulin and complements. The existence of differences in processes governing lead release from these Pb(ll) solids is supported by SEM data showing different patterns of morphological changes of the cerussite and hydrocerussite crystal surfaces. Recent improvements in survival have been achieved without further increases in the risk of infants developing chronic lung disease. The mandible was advanced 6.0 mm on the right side, and the maxilla was impacted 4.0 mm at ANS, 2.0 mm at the right first molar, and 5.0 mm at the left first molar. Nevertheless, both techniques should be considered as complementary until more extensive and randomized studies can confirm these results. We describe the DFSS process and provide an example of its application to an employee influenza vaccination program at a New England hospital.

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