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Azirox (Azithromycin)
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Azirox

Azirox is a macrolide antibiotic of azalides group. Azirox contains Azithromycin as an active ingredient. Azirox inhibits RNA-dependent protein synthesis of sensitive microorganisms. It active against gram-positive bacteria: Staphylococcus aureus, Streptococcus spp. (including Streptococcus pneumoniae, Streptococcus pyogenes group A); gram-negative bacteria: Haemophilus influenzae, Haemophilus parainfluenzae, Haemophilus ducreyi, Moraxella catarrhalis, Escherichia coli, Bordetella pertussis, Bordetella parapertussis, Borrelia burgdorferi, Neisseria gonorrhoeae, Campylobacter spp., Legionella pneumophila; anaerobic bacteria: Bacteroides fragilis.

Other names for this medication:
Azatril, Azihexal, Azinil, Azitropharma, Azycyna, Binozyt, Disithrom, Faxin, Gramokil, Magnabiotic, Misultina, Neofarmiz, Neozith, Ribotrex, Sitrox, Texis, Toraseptol, Tremac, Tritab, Unizitro, Vinzam, Zertalin, Zifin, Zinfect, Zithrin, Zitromax

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Also known as: Azithromycin

Description

Azirox is a semi-synthetic macrolide antibiotic of the azalide class. Like other macrolide antibiotics, Azirox inhibits bacterial protein synthesis by binding to the 50S ribosomal subunit of the bacterial 70S ribosome. Binding inhibits peptidyl transferase activity and interferes with amino acid translocation during the process of translation. Its effects may be bacteriostatic or bactericidal depending of the organism and the drug concentration. Its long half life, which enables once daily dosing and shorter administration durations, is a property distinct from other macrolides.

Azirox is the local analog (generic) of more famous drug Azirox that has the same active substance (ingredient) and in result the same therapeutic effect. The main difference is that Azirox is registered by a small local pharmaceutical company. The presence of the same active substance guarantees an identical pharmaceutical (therapeutic) effect on the body.

It is possible to buy Azirox only in the pharmacies of the country where it is produced. With us, you can buy its more famous analog Azirox, which is approved by the FDA and is sold worldwide. The same active substance guarantees the identity of the drugs and the identity of the pharmaceutical properties (they have only different names and packaging, in which they are sold).

Dosage

Generic Azirox is available in: 250 mg (Low Dosage), 500 mg (Standard Dosage).

Generic Azirox can be taken in tablets, liquid form, injections. You should take it by mouth with water.

To avoid problems with stomach, take tablets and liquid form with meals. Liquid Generic Azirox form should be shook properly. Capsule is taken on empty stomach.

It is better to take Generic Azirox every day at the same time.

Generic Azirox treats different types of bacterial infections and can be used both by adults and by children. Thus, each age has different instructions.

For children it is better to take into account child weight. In treatment of otitis media, take Generic Azirox for 1-5 days.

For Adults: if you treat Pneumonia or Throat/Tonsil Infection the right dose is two tablets of 250 mg on the first day and then 250 mg once a day for 4 more days.

In prevention of MAC (mycobacterium avium complex) usual Generic Azirox dosage is 1,200 mg for a week.

In treatment of skin or infections usual Generic Azirox dosage is two tablets of 250 mg at the first day after you took one tablet of 250 mg for 4 days at the same time.

Overdose

Seek emergency medical attention if you think you have used too much of this medicine. Symptoms of an Azirox overdose may include nausea, vomiting, diarrhea, and stomach discomfort.

Storage

Store at room temperature between 59-77 F (15-25 C) away from light and moisture, kids and pets. Do not store the liquid longer than 10 days.

Side effects

The most common side effects associated with Azirox are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.

Contraindications

Ketolide allergy. History of cholestatic jaundice/hepatic dysfunction associated with prior use.

Pneumonia: oral treatment is for mild, community-acquired cases suitable for outpatient therapy only. Discontinue if signs/symptoms of hepatitis occur. Known QT prolongation, proarrhythmic conditions, clinically significant bradycardia: avoid. Allergic symptoms may recur after initial successful symptomatic treatment. Myasthenia gravis. Hepatic or renal impairment. Elderly. Pregnancy (Cat.B). Nursing mothers.

Avoid concomitant aluminum- or magnesium-containing antacids. Monitor with digoxin, phenytoin, warfarin. Monitor for azithromycin toxicity (eg, liver dysfunction, ototoxicity) with nelfinavir. Concomitant Class 1A (eg, quinidine, procainamide), or Class III (eg, dofetilide, amiodarone, sotalol) antiarrhythmics, or others known to prolong the QT interval: avoid.

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Lip and tongue resting postures, along with swallowing patterns, were corrected to a highly significant degree. Genotyping of 12 of these 16 isolates with polymorphisms at the SAG2 locus indicated that 4 were type III, and 8 were type II. The aim of this research is to study which presentation mode is preferable for improving adherence. Acid-base imbalances may have serious clinical implications for all patients. ICI and CJP reconstruction result in a similar functional outcome and quality of life. TH mRNA levels were found to increase 2- to 5-fold after continuous treatment for 1-12 h with 50 mM KCl. Several indices of blood coagulation and fibrinolytic activity in tick-transmitted rickettsiosis. In any individual patient it may be difficult to separate the contribution of TPN itself from that of the other precipitating causes. In the absence of specific systems for monitoring prescription opioid-related deaths in Canada, readily available national vital statistics data can be used to study prescription opioid-related mortality with considerable accuracy.

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We propose that the interaction of pp120 with the juxtamembrane domain is indirect and requires one or more substrates that bind to Tyr960 in the insulin receptor. This lectin-like protein is devoid of monosaccharide binding properties and belongs to the phytohemagglutinin protein family. Tumor necrosis factor-alpha, transforming growth factor-beta, and tetradecanoylphorbol acetate: competence factors for ML-1 human myeloblastic leukemia cell differentiation. Tm, k(cat), and Km) involving protein stability and enzyme function have generally been the focus of inquiries into the efficacy of naturally occurring osmolytes like trimethylamine-N-oxide (TMAO), to offset the deleterious effects of urea on the intracellular proteins in the urea-rich cells of elasmobranchs. Metallicity is achieved down to 6 K despite the polycrystalline morphology. The present study was designed to develop an animal model of multiple risk factors, including obesity, hypertension, non-insulin-dependent diabetes mellitus, and hyperlipidemia. This study aimed to investigate the putative involvement of IGFBP2 in mood disorder pathogenesis by measuring its expression levels in patient peripheral tissues. Application of a breakthrough biosorbent for removing heavy metals from synthetic and real wastewaters in a lab-scale continuous fixed-bed column. The ratio between cardiac width and the other 5 indices was calculated.

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In vitro analyses revealed that both plant extracts exerted their anti-HSV-2 effects by interfering with viral cell attachment and entry, but could not block viral replication post entry. Systematic revue of the tools for multiprofessional primary care teams assessment. Less pronounced changes were seen in blood plasma serotonin and histamine. It is of utmost importance that patients and their family members be informed both of possible sequelae and of life-saving interventions to be administered at early diagnosis. Glomerulo-tubular balance in diabetes mellitus: molecular evidence and clinical consequences. Validating the importance of two acetylcholinesterases in insecticide sensitivities by RNAi in Pardosa pseudoannulata, an important predatory enemy against several insect pests. Standing Classrooms: Research and Lessons Learned from Around the World. This temovate ointment cost is evident when we compare the Middle Eastern end-of-life experience with the western end-of-life care. Multiple shoulder abscesses in a patient with rheumatoid arthritis. Serum vitamin A levels were determined in two groups of subjects living in an endemic goiter area in Iran.

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Immunoreactive inhibin in follicular fluid is related to meiotic stage of the oocyte during final maturation of the porcine follicle. Simulations were then applied to evaluate the reduction rate of each antagonist on the reversal of the THC-induced effect in a unified simulation scenario. Cell cultures derived from peripheral neurofibromas and from skin biopsies of healthy persons were used as indicator cells. There is now good epidemiological evidence that mild hyperhomocysteinaemia is an independent risk factor in the development of arterial disease and venous thrombosis although the causes of the elevated plasma homocysteine are unclear. Our aim was to compare EUS, CT, and magnetic resonance imaging (MRI) findings of RMT and to explore the potential impact on cancer staging. Cardiogenic shock in a patient being treated with atezolizumab for metastatic non-small cell lung cancer.

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Three of them had the typical symptoms of DIOA: reduced visual acuity, tritan defect, temporal pallor of both optic discs, and a relative central scotoma for white test spots. Serotonin syndrome (SS) is a potentially life-threatening condition associated with increased serotonergic activity in central nervous system and may occur during the use of serotonergic drugs. This finding supports our cell-based approach to screen for FtsZ inhibitors and opens new possibilities for peptide inhibitors of bacterial cell division. It has been observed that acetaminophen potentiates the analgesic effect of morphine and tramadol in postoperative pain management. We compared the Cancer and Aging Research Group (CARG) tool, the Vulnerable Elders Survey-13 (VES-13), and oncologist judgment in predicting toxicity in men with mCRPC undergoing chemotherapy. The systemic application of several peptides for experimental detection and treatment of bone and soft-tissue infection is also discussed in this review. Projection at the level of the somato-motor cortex of the monkey of afferences from muscle receptors.

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Learning, memory and synaptic plasticity in hippocampus in rats exposed to sevoflurane. Reliable and efficient solution of genome-scale models of Metabolism and macromolecular Expression. Failure of transradial approach during coronary interventions: anatomic considerations. Systemic anti-CD18 treatment induced a pronounced increase in the number of circulating mononuclear and polymorphonuclear cells with a maximum at 24 hr after injection of the antibody. Children on ZDV need to be monitored very closely (at least monthly) for hematologic side effects, which are most common in the more seriously ill children. Differences in food intake and genetic variability in taste receptors between Czech pregnant women with and without gestational diabetes mellitus. Functionalized Stress Component onto Bio-template as a Pathway of Cytocompatibility. The magnitude of the cytotoxic effector cell response depends on the time at which helper T cells become activated: early helper activity steeply increases the magnitude of the immune response. The Light Field Attachment: Turning a DSLR into a Light Field Camera Using a Low Budget Camera Ring. We identified 3 critical factors, whose presence was necessary for game engagement: purpose (explicit purpose known by the user), user alignment (congruency of game and user objectives), and functional utility (a well-designed game).

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