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Azelastine

Azelastine is used to relieve nasal symptoms such as runny nose, itchy nose, stuffy nose, sneezing, and post-nasal drip caused by allergies or other conditions. Azelastine nasal spray causes sleepiness. Don't drive, use machinery, or do other dangerous activities until you know how Azelastine affects you.

Other names for this medication:
Astepro, Azelast, Azelastine, Azenate, Duonase, Nazomac, Oculast, Optihist, Optivar

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Description

Azelastine (azelastine) is an antihistamine that reduces the effects of natural chemical histamine in the body. Histamine can produce symptoms of sneezing, itching, watery eyes, and runny nose.

Azelastine nasal spray is used to treat sneezing, runny or stuffy nose, itching, and other nasal symptoms of allergies, in adults and children who are at least 5 years old.

Azelastine is also used to treat ongoing nasal symptoms (runny or stuffy nose, sneezing, itching) that are not caused by allergies, in adults and children who are at least 12 years old.

Dosage

This section provides information on the proper use of a number of products that contain azelastine. It may not be specific to Azelastine Ready-Spray. Please read with care.

Use this medicine only as directed by your doctor. Do not use more of it and do not use it more often than your doctor ordered. To do so may increase the chance of side effects.

This medicine usually comes with patient information insert. Read and follow the instructions carefully. Ask your doctor if you have any questions.

Follow the instructions on the medicine label if you are using this medicine without a prescription.

This medicine is for use only in the nose. Do not get any of it in your eyes or on your mouth. If it does get on these areas, rinse it off with water and call your doctor right away.

Do not use this medicine for any other nose problem (eg, ulcers or surgery, or injury that has not healed) without checking with your doctor first.

To use the spray:

When you use the azelastine nasal spray for the first time, you must prime the spray. Press down fully 6 times or until a fine spray comes out. Prime the spray after each time you clean the pump, or if you have not used the medicine for 3 days or longer, by spraying the medicine 2 times or until a fine spray comes out. Blow your nose to clear your nostrils. Tilt your head down, looking at your toes, and insert the tip of the nose piece into your nostril. Hold bottle upright and aim the spray tip toward the back of your nose. Tilt your head downward while spraying to avoid a bitter taste in the mouth. Close your other nostril with a finger. Press the pump 1 time and sniff gently at the same time, keeping your head tilted forward and down. Repeat in your other nostril using the same steps. If your healthcare provider tells you to use 2 sprays in each nostril, repeat the steps above for the second spray in each nostril. Do not blow your nose or tip your head back after using the spray. Wipe the tip of the outside of the nose piece with a clean, dry tissue or cloth and put the cap back on.

Do not drink alcohol while you are using this medicine.

The dose of this medicine will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of this medicine. If your dose is different, do not change it unless your doctor tells you to do so.

The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.

For nasal dosage form (Azelastine® spray): For treatment of seasonal allergic rhinitis: Adults and children 12 years of age and older—1 or 2 sprays in each nostril 2 times a day, or 2 sprays in each nostril once a day. Each spray contains 137 or 205.5 micrograms (mcg) of azelastine. Children 6 to 11 years of age—1 spray in each nostril 2 times a day. Each spray contains 137 or 205.5 mcg of azelastine. Children 2 to 5 years of age—1 spray in each nostril 2 times a day. Each spray contains 137 mcg of azelastine. Children younger than 2 years of age—Use and dose must be determined by your doctor. For nasal dosage form (Astepro® spray): For treatment of perennial allergic rhinitis: Children 6 months to 11 years of age—1 spray in each nostril 2 times a day. Each spray contains 137 micrograms (mcg) of azelastine. Children younger than 6 months of age—Use and dose must be determined by your doctor. For treatment of seasonal allergic rhinitis: Adults and children 12 years of age and older—1 or 2 sprays in each nostril 2 times a day. Each spray contains 137 micrograms (mcg) of azelastine. Children 2 to 11 years of age—1 spray in each nostril 2 times a day. Each spray contains 137 mcg of azelastine. Children younger than 2 years of age—Use and dose must be determined by your doctor. For nasal dosage form (Astepro® allergy spray): For treatment of allergic rhinitis or other upper respiratory allergies: Adults and children 12 years of age and older—2 sprays in each nostril once a day or 1 or 2 sprays in each nostril 2 times a day (every 12 hours). Do not use more than 4 sprays in each nostril per day (24 hour period). Each spray contains 205.5 micrograms (mcg) of azelastine. Children 6 to 11 years of age—1 spray in each nostril 2 times a day (every 12 hours). Do not use more than 2 sprays in each nostril per day (24 hour period). Each spray contains 205.5 micrograms (mcg) of azelastine. Children younger than 6 years of age—Use is not recommended.

Overdose

If you overdose Azelastine and you don't feel good you should visit your doctor or health care provider immediately.

Storage

Store at a room temperature between 15 and 30 degrees C (59 and 86 degrees F) away from moisture and sunlight. Keep in a tightly closed container. Throw away the after the expiration date. Keep out of the reach of children.

Side effects

The most common side effects associated with Azelastine are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.

Contraindications

Appropriate studies performed to date have not demonstrated geriatric-specific problems that would limit the usefulness of Astepro® nasal spray in the elderly. However, elderly patients are more likely to have age-related kidney, liver, or heart problems, which may require caution and an adjustment in the dose for patients receiving this medicine.

No information is available on the relationship of age to the effects of Astepro® allergy nasal spray in geriatric patients.

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We propose that the binding sites for promoter DNA and 6S RNA on region 4.2 of sigma(70) are overlapping but distinct, raising interesting possibilities for how core promoter elements contribute to defining promoters that are sensitive to 6S RNA regulation. As might be expected, the type and severity of psychiatric morbidity and the category of health professional seen were also associated with receiving particular types of mental health help. Data mining tools identified three differentiable segments by means of cluster analysis. We also examined the role of nNOS in dopamine/DARPP-32 signaling in striatal slices from nNOS KO mice and the effects of the administration of a dopamine D1 receptor agonist on behavior in nNOS KO mice. We fully acknowledge the limitations of our work, which is intended as a starting point for future efforts and not to be definitive. Systemic minocin 50 mg para que sirve lupus erythematosus presenting with drug-unrelated acute pancreatitis as an initial manifestation. The recruitment of SL RNA to the spliceosome depends on splicing factors and recent progress in identifying such factors is described. By taking advantage of a low temperature salt flux synthetic method, these unique phases can be more easily synthesized and separated as phase pure materials. The repertoire of Na,K-ATPase alpha and beta subunit genes expressed in the zebrafish, Danio rerio. Herpes viruses in periodontal compromised sites: comparison between HIV-positive and -negative patients.

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