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Asuzol (Metronidazole)
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Asuzol

Asuzol is an antibiotic and antiprotozoal medication. It is used either alone or with other antibiotics to treat pelvic inflammatory disease, endocarditis, and bacterial vaginosis. It is effective for dracunculiasis, giardiasis, trichomoniasis, and amebiasis.

Other names for this medication:
Amotein, Amotrex, Anabact, Anerobia, Corsagyl, Deprocid, Dirozyl, Fladex, Flagolin, Flanizol, Florazole, Fortagyl, Mebadiol, Mecozol, Menilet, Menizol, Metco, Metral, Metrazol, Metrin, Metroderme, Metronidazole, Metronidazols, Metroson, Minegyl, Mtronidazole, Nalox, Negazole, Nidazole, Padet, Polibiotic, Protozol, Repligen, Riazole, Rosazol, Rovamet, Rozagel, Stomorgyl, Trichazole, Trichodazol, Tricofin, Triconex, Tricozyl, Vagizol, Varizil, Venogyl

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Also known as: Metronidazole

Description

Metronidazole injection is used to treat serious bacterial infections in different areas of the body. It is also used to prevent infections in the bowels before and after surgery for some patients.

Metronidazole belongs to the class of medicines known as antibiotics. It works by killing bacteria or preventing their growth. However, this medicine will not work for colds, flu, or other virus infections.

This medicine is to be given only by or under the direct supervision of your doctor.

Dosage

The usual adult oral dosage is 7.5 mg/kg every six hours (approx. 500 mg for a 70-kg adult). A maximum of 4 g should not be exceeded during a 24-hour period.

The usual duration of therapy is 7 to 10 days; however, infections of the bone and joint, lower respiratory tract, and endocardium may require longer treatment.

Patients with severe hepatic disease metabolize metronidazole slowly, with resultant accumulation.

Overdose

Single oral doses of Asuzol, up to 15 g, have been reported in suicide attempts and accidental overdoses. Symptoms reported include nausea, vomiting, and ataxia. Oral Asuzol has been studied as a radiation sensitizer in the treatment of malignant tumors. Neurotoxic effects, including seizures and peripheral neuropathy, have been reported after 5 to 7 days of doses of 6 to 10.4 g every other day.

There is no specific antidote for Asuzol overdose; therefore, management of the patient should consist of symptomatic and supportive therapy.

Storage

Store Asuzol at room temperature, between 68 and 77 degrees F (20 and 25 degrees C). Store away from heat, moisture, and light. Do not store in the bathroom. Keep Asuzol out of the reach of children and away from pets.

Side effects

The most common side effects associated with Asuzol are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.

Contraindications

Metronidazole should be used with caution in patients with active disease of the Central Nervous System. The treatment should be withdrawn in case of ataxia, dizziness, or confusion. The risk of aggravation of the neurological state should be considered in patients suffering from severe central and peripheral neurological diseases, fixed or progressive paraesthesia and epilepsy. Caution is required in patients with active disease of the central nervous system except for brain abscess.

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