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Artisid (Indomethacin)

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Artisid belongs to a group of medicines called nonsteroidal anti-inflammatory drugs (NSAIDs). It works by blocking chemical messengers in the brain that tell us we have pain. It can help relieve pain in conditions like rheumatoid arthritis and osteoarthritis.

Other names for this medication:
Artid, Artisid, Donica, Ducain, Edcin, Idicin, Indmecin, Indoc, Indocap, Indocid, Indoflam, Indol, Indomethacin, Indonet, Indopar, Indoriv, Inmecin, Inocin, Methadocin, Microcid, Recticin, Tissop

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Also known as: Indomethacin


Indomethacin injection is used to treat patent ductus arteriosus (PDA) in premature infants (babies born too early) who weigh between 500 and 1750 grams. PDA is a heart problem where a blood vessel, the ductus arteriosus, fails to close normally after birth. This blood vessel is only used before birth, and is no longer needed after the baby is born. Indomethacin injection works by causing the PDA to constrict, and this closes the blood vessel. This medicine is used when other medical treatment for PDA fails after 48 hours.

This medicine is available only with your doctor's prescription.


This section provides information on the proper use of a number of products that contain indomethacin. It may not be specific to Artisid. Please read with care.

For safe and effective use of this medicine, do not use more of it, do not use it more often, and do not use it for a longer time than your doctor ordered. Using too much of this medicine may increase the chance of unwanted effects.

This medicine should come with a Medication Guide. Read and follow these instructions carefully. Ask your doctor if you have any questions.

When used for severe or continuing arthritis, this medicine must be used regularly as ordered by your doctor in order for it to help you. This medicine usually begins to work within one week, but in severe cases up to two weeks or even longer may pass before you begin to feel better. Also, several weeks may pass before you feel the full effects of this medicine.

Do not take rectal suppositories by mouth or use it in the vagina.

To use the suppository:

If the suppository is too soft to insert, chill it in the refrigerator for 30 minutes or run cold water over it before removing the foil wrapper. Remove the foil wrapper and moisten the suppository with cold water. Lie down on your side and use your finger to push the suppository well up into the rectum Remain lying down for about 15 minutes to keep the suppository from coming out before it melts. Make sure to wash your hands with soap and water before and after inserting this medicine.

The dose of this medicine will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of this medicine. If your dose is different, do not change it unless your doctor tells you to do so.

The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.

For rectal dosage form (suppositories): For moderate to severe ankylosing spondylitis, osteoarthritis, or rheumatoid arthritis: Adults and children older than 14 years of age—One 50-milligram (mg) suppository, inserted into the rectum up to 3 times a day. Children up to 14 years of age—Use and dose must be determined by your doctor. For acute painful shoulder caused by bursitis or tendinitis: Adults and children older than 14 years of age—One suppository inserted into the rectum 3 to 4 times a day. Children up to 14 years of age—Use and dose must be determined by your doctor. For gout: Adults and children older than 14 years of age—One suppository inserted into the rectum 3 times a day. Children up to 14 years of age—Use and dose must be determined by your doctor.


Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.

Overdose symptoms may include severe drowsiness, stomach pain, or vomiting.


Store at room temperature between 15 and 30 degrees C (59 and 86 degrees F) away from moisture and heat. Keep container tightly closed. Throw away any unused medicine after the expiration date. Keep out of the reach of children.

Side effects

The most common side effects associated with Artisid are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.


Avoid alcohol. Heavy drinking can increase your risk of stomach bleeding.

Avoid taking aspirin unless your doctor tells you to.

Ask a doctor or pharmacist before using other medicines for pain, fever, swelling, or cold/flu symptoms. They may contain ingredients similar to Artisid (such as aspirin, ibuprofen, ketoprofen, or naproxen).

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Identification of optimal hyperspectral bands for estimation of rice biophysical parameters. Rapid separations of nile blue stained microorganisms as cationic charged species by chip-CE with LIF. To assess the influence of dietary restrictions on psychological development in adolescents with coeliac disease. Overall, GIST xenografts responded rapidly to panobinostat as indicated by tumor regression, necrosis, hemorrhages, fibrosis, and/or myxoid degeneration, remarkable apoptosis, and substantial decline of cell proliferation. Intravitreal infliximab shows dual effect on the development of laser-induced CNV. Our results demonstrate that agrin function is acutely required for pre- and postsynaptic differentiation in vitro, and strongly suggest that agrin is directly involved in the induction of presynaptic differentiation. The article focuses on the pathogenesis of chronic urethrogenic prostatitis. Occurrence, characterization, and potential predictors of verotoxigenic Escherichia coli, Listeria monocytogenes, and Salmonella in surface water used for produce irrigation in the Lower Mainland of British Columbia, Canada. However, postoperative wound complications often require additional soft-tissue coverage to salvage the initial reconstruction.

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Induction of fatty-acid-synthase gene expression by glucose in primary culture of rat hepatocytes. Pregnant and nonpregnant women in cape town, South Africa: drug use, sexual behavior, and the need for comprehensive services. Samples from affected and healthy skin surfaces were obtained with adhesive tape, and dust samples from bedding and clothes were collected with a vacuum cleaner at the start of the study and 3-6 weeks later, and examined for the presence of house dust mites. To test the efficacy of synthesized siRNAs targeting P2Y(2)-R, immunocytochemistry, immunohistochemistry, and quantitative RT-PCR (qRT-PCR) assays were performed. The molar ratio of hydrazine to HAuCl(4) was found to be an important parameter in the control of size and shape for the production of gold nanoparticles. Viral load and mRNA expression of HPV type 6 among cases with recurrent respiratory papillomatosis.

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Anti-Eg5 antibodies were used to investigate localization of Kinesin-5-like proteins in brown algal zygotes. The M and C regions comprise the major contacts involved in subunit interaction, likely with multiple sites in the exonuclease (exo) region and part of the spacer between the exo and DNA polymerase (pol) regions in the catalytic subunit. Up to now, no consensus exists about the electronic nature of phosphorus (P) as donor for SiO2-embedded silicon nanocrystals (SiNCs). These receptors have emerged as important sensors for FFA levels in the circulation or the gut lumen, based on evidence from in vitro and rodent models, and an increasing number of human studies. Assignment of the human homolog of mouse Dlx3 to chromosome 17q21.3-q22 by analysis of somatic cell hybrids and fluorescence in situ hybridization.

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There has been an erosion of employer-based health insurance and a concomitant rise in children covered by public health insurance programs, yet more than 8 million children are still without health insurance coverage. Unfortunately, the significance of these observations remains uncertain given methodological differences between studies including a lack of controls. The library data led us to identify the proteoglycan neurocan as a novel MMP-2 substrate. It provides a realistic pathway from diagnosis to LB and accounts for the majority of costs and outcome possibilities. Our results showed that high expression of all the studied miRNAs in biopsies and miR-142-3p and miR-223 in PBMC samples could be used as suggestive diagnostic tools to discriminate ATCMR patients from NA. It has been shown that heterodimers of DPP and 60A classes of bone morphogenetic proteins (BMPs) are more potent than each homodimers in bone and mesoderm induction in vitro, suggesting that BMP4 and BMP8B may form heterodimers to induce PGCs.

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Fab fragments and an antibody to glycophorin C had no effect on band 3 rotational mobility. The toxin causes alteration of the host cell actin cytoskeleton and promotes bacterial invasion of blood-brain barrier endothelial cells. The choice of pulmonary drug delivery systems remains critical as air-jet and ultrasonic nebulizer may deliver sub-optimum drug concentration if not used properly. Data from the 1991 Medicare Current Beneficiary Survey (MCBS) on 8,859 persons age 65 and over living in the community. Thus, we aimed to explore the possible molecules and pathways by using bioinformatics methods Consequently, two datasets (GSE8865 and GSE31286) were retrieved and the differentially expressed genes (DEGs) were screened out. Robust and exact structural variation detection with paired-end and soft-clipped alignments: SoftSV compared with eight algorithms. The accuracy of MRI for diagnosing meniscal tears in older patients is high and similar to that in younger patients when only definitive findings are considered a tear. Here we demonstrate that IkappaBalpha interacts directly with another nucleocytoplasmic shuttling protein, hnRNPA1, both in vivo and in vitro.

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Experimental Characterization of the Anatomical Structures of the Lumbar Spine Under Dynamic Sagittal Bending. A decreased generation of activated protein C is a procoagulant consequence of the TM-dependent thrombin inhibition by PCI. Five cases of axillary lymph node metastatic breast cancer on contrast-enhanced sonography. Moreover, analysis using pharmacological inhibitors against MEK1/2, ERK1/2, JAK-II, and phospho-STAT3 demonstrated that AT1R-mediated stimulatory effect of A-II on PAX2 expression was regulated in part by the phosphorylation of ERK1/2, JAK II, and STAT3 pathways. The target compounds were prepared conveniently from (5alpha)-3-hydroxyandrostan-17-ones (6 and 7) via the intermediate (5alpha)-17-aza-D-homoandrostan-3-ols (14 and 15) or (5alpha)-17-azaandrostan-3-ols (18 and 19) precursors in high overall yields. Highly efficient base excision repair (BER) in human and rat male germ cells. Followup consisted of physical examination 14 days, 6 months and 1 year postoperatively, when testicular position and size were assessed. The findings support relevant moderation by age, gender, and family history in nearly all studies and suggest a strong need for consideration of non-linearity in the exposure-response analyses. The objective of this study was to assess the concordance between TTE and CMR for the estimation of valve EOA.

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Data obtained in the present study confirm the high prevalence rates of mental disorders in obese patients seeking treatment. Even the effects of moderate sleep loss on life and health quality can be similar to sleep deprivation. Patients with HP were identified by a review of a structured EUS database. To investigate the effects of angiotensin II type 1 receptor (AT1R) knockdown on the first-phase insulin secretion in isolated islets of db/db mice and explore the possible mechanisms. However, the extent of associated abnormalities should not deter paediatricians to refer patients for treatment.

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Laparoscopic 3-step restorative proctocolectomy: comparative study with open approach in 45 patients. The purpose of this study of the Alberta Provincial Project for Outcome Assessment in Coronary Heart Disease (APPROACH) was to examine the association between treatment and survival up to 5 years in patients with MVD enrolled from 1995 through 1998. In these patients with borderline PSA value extent of disease is most difficult to predict. The association between meat and egg consumption and breast cancer risk has been examined in previous studies, but the results were inconsistent. Expression of these genetic constructs failed to induce a nonspecific interferon response. In Arabidopsis, GUS activity was only found in the rosette leaf trichomes and rosette leaf vascular tissue, indicating that the transcription factors which bind to PGbEXPA2 in the leaf trichomes of transgenic Arabidopsis were similar to those found in cotton fiber. At 6-month follow up, the patient had returned to his cognitive baseline, speaking fluently and appropriately. Therefore, in this review we focus upon hematologic malignancies.

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Dot-blot hybridization with cloned genomic DNA labeled with photobiotin as a probe is used to detect Plasmodium falciparum sporozoites in dried mosquitoes. This study provides normative data for ambulatory manometry for comparison when studying patients with disease. The simulation result implies that such collective chemotaxis behavior is due to a synchronized signaling pathway across the bacteria attached to the same microswimmer. These data suggest that immunotoxin therapy might be used in combination with pentostatin plus cyclophosphamide chemotherapy to improve the targeted therapy of cancer. These patients were randomed in two longitudinal studies each with 3 treatment arms comparing postoperative irradiation with 4 x 3 Gy (101 patients), 1 x 5 Gy (93 patients), 1 x 7 Gy (95 patients) and the postoperative use of the NSAID indometacin for 7 days (113 patients) respectively for 14 days (90 patients) und acetyl salicyl acid (ASS) for 14 days (93 patients).

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We describe the first reported case of DBS infection due to a novel rapidly growing mycobacteria, most closely resembling Mycobacterium goodii, by rpoB gene sequencing. The TNF response was partly inhibited with antibodies against CD14, which is a well-known receptor for lipopolysaccharide (LPS). Prospective trials should confirm the clinical relevance of WT1 mutations in relation to other prognostic factors in patients with AML. Serum tumor markers in patients with cancer assist with establishing diagnosis, estimating prognosis, monitoring treatment, and detecting tumor recurrence. However, their performance in clinical trials has been disappointing. The localization of nerve fiber defects corresponds to the localization of the visual field defect exactly in eight of 15 eyes and roughly in another five. Our re-analysis supports our previous finding that gene expression data are significantly more consistent than drug sensitivity measurements. To contrast the neuropsychological profiles of Parkinsonian patients, before and after fetal ventral mesencephalic tissue transplantation. Retrospective and descriptive study of patients referred to a Pediatric Hematology unit of a tertiary hospital for possible coagulopathy during 2012.

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This result suggests that some components of the hAH proteome are involved in this disease. Organization of epidemiological measures in surroundings of patients with active pulmonary tuberculosis with undetermined bacterial discharge. However, it may protonix medication mg in elderly occur as a pathologic process, especially in sports with repetitive overhead activity. Highly regioirregular polypropylene from asymmetric group 4 anilide(pyridine)phenoxide complexes. This variability indicates the requirement of multiple markers for a comprehensive TAI evaluation and multiple targeted treatments for TAI polypathology within its therapeutic window time frame. The analyses were performed by caspase assay, flow cytometry, Western blotting, immunoprecipitation and fluorescent microscopy. Resurgence is of particular interest because it may be a source of relapse to problem behavior following treatments involving alternative reinforcement. Biopsychological relationships and prediction of the course of acute viral hepatitis.

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The performance of three conventional enzyme and radioimmunoassays routinely used to detect residues of anabolic steroids in cattle sera were compared with dissociation enhanced lanthanide fluorescence immunoassay (DELFIA) kits designed for the hospital market. The short dosimeter protocol with quadrupling doses for AMP challenges is a rapid, reproducible tool for estimating bronchial responsiveness in population surveys. Estimates of RRD incidence have varied threefold, but inclusion criteria and other design features have differed across studies making direct comparisons difficult. Dietary fat alters the distribution of cholesterol between vesicles and rocaltrol tab uses micelles in hamster bile. Preovulatory treatment of mice with anti-VEGF receptor 2 antibody inhibits angiogenesis in corpora lutea. Thrombophilia is the second most frequently observed risk factor and is related to the high prevalence of factor V-Leiden and MTHFR C 677 T mutation among the Lebanese population. We studied 228 pediatric patients (4-15 y old) and 235 adults (30-45 y old) who underwent abdominal and pelvic CT scans for reasons not related to the spine. In vivo formation of a human beta-globin locus control region core element requires binding sites for multiple factors including GATA-1, NF-E2, erythroid Kruppel-like factor, and Sp1.

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In the era of precision medicine, drugs are increasingly developed to target subgroups of sumycin antibiotic patients with certain biomarkers. For brevity, only the results for sources 1.0-cm, 3.0-cm, and 5.0-cm long are presented here. His approach was based on the theory that breast cancer was an essentially localized disease and progressed gradually through the lymphatic chains to the distant organs. In 4 of these 7 patients, a review of the medical record documented neurologic symptoms that were not recognized as typical of multiple sclerosis. Delayed pulmonary toxicity syndrome following high-dose chemotherapy and bone marrow transplantation for breast cancer. The variability of acceptance within the same profession group differs between the situations.

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We evaluated 28 patients with complicated UHPs who had undergone total hip arthroplasty a very long time previously (range 3-20 years, mean 8.4). Irritable bowel syndrome (IBS) is a spectrum of disorders characterized by abdominal discomfort and pain, associated with altered bowel habits. We succeeded in detecting 10 ng/L (10 ppt) of atrazine using both DNA and PNA probes. A variety of DNA binding proteins are involved in regulating and shaping the packing of chromatin. The consecutive coronal CT scans of 100 patients that included 43 males and 57 females were evaluated. Extraction of charged fusion proteins in reversed micelles: comparison between different surfactant systems. Since MS is a polygenic disease, there must be several susceptible genes other than HLA. Development of the headspace YSSS contributes a new client satisfaction scale with tested psychometric properties for adolescents and young adults engaged in mental health services, providing an essential tool for youth mental health services to routinely evaluate the experiences of young people accessing their services. In chronically malnourished bactrim drug name anorexia nervosa patients, nutritional support should be instituted gradually to avoid rapid electrolyte shifts and fluid overload. We describe and evaluate efforts to improve the follow-up care of patients with abnormal Papanicolaou test results at an academic family practice center at Shadyside Hospital in Pittsburgh.

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Modulation of the GH and IGF-1 system may therefore provide a useful therapy in the prevention of age-associated changes in the cardiovascular system and in future regenerative cell-based therapies. Cardiogenic causes can be further divided into reflex, orthostatic, and primary cardiac disorders, allowing for more focused diagnostic testing. To examine the use of social support behaviors by primary care providers during delivery of positive newborn screening results for Sickle Cell Anemia carrier status. This study investigated the role of the cannabinoid CB1 receptor agonist, WIN 55,212-2, on motor activity. Biochemically, Sini Tang also reversed CUS-induced increases in corticosterone in plasma and CRH mRNA in the hypothalamus. It was found that individuals high in NFC recognised more presented attributes and falsely recognised more associative critical lures. Apparent diffusion coefficient (ADC) value from DWI and ADC from DTI (ADC) map and fractional anisotropy (FA) values from DTI were analyzed and aygestin generic compared statistically. Isolated fracture of the humeral trochlea: a case report and review of the literature. Suicide victims were more likely to have had a mood disorder, family history of psychiatric problems, mention of suicide risk in chart notes and a previous suicide attempt. The cellular sources of these chemokines comprise both the blood-derived polymorphonuclear leukocytes (PMNs) and monocytes infiltrating the meninges, the ventricular system and the periventricular area.

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To elucidate the dynamics of FSH, LH, prolactin (PRL), TSH and insulin secretion in women with polycystic ovarian syndrome (PCOS) treated with metformin (MET). Green tea catechins decrease oxidative stress in surgical menopause-induced overactive bladder in a rat model. This study aimed to determine the effect of aromatherapy on the quality of sleep in postpartum women. Ammonia sensitivity of the glass eel (Anguilla anguilla L.): salinity dependence and the role of branchial sodium/potassium adenosine triphosphatase. The C sign is specific, but not sensitive, for flatfoot deformity, and is neither sensitive nor specific for subtalar coalition. Double labeling experiments revealed that at these levels (caudal L1 and rostral L2), the abdominal muscle motoneurons were located dorsomedial to the psoas and iliacus motoneurons. While all pairs escalated their playful encounters to become rougher, only the pairs in which one member was devocalized escalated to serious biting. The analysis of the invasive diagnostic procedures (video-mediastinoscopy, anterior mediastinotomy, and thoracoscopy) shows that in most cases, a part from the kind of anesthesia, could be done in a short-term hospitalization.

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The STS was used to amplify DNA from somatic cell hybrids to localise TPM2 to human chromosome 9. The study group consisted of 123 children, the control one--of 127. This qualitative scoring system may serve as the first step to a semi-quantitative score for tendon pathology. Multiple dose administration of omeprazole increased the Cmax, AUC0-infinity and elimination half life (t1/2e) of carbamazepine. A well-known gradient of a desired molecule was generated on the bottom surface of a hydrogel, which was then used as a stamp to immobilise the molecule on a functionalised substrate. The antimicrobial test indicated that the high-purity CAD had strong antimicrobial activity against E. Increasing evidence suggests that nanotube structures mediate cytoplasmic molecular trade among neighboring cells of the same and different species.

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Further rigorous research using appropriate outcome measures to evaluate the effectiveness of interventions for young people with visible differences is required. A total of 10 obese nondiabetic male patients were studied before and after a 14-day treatment with 2,550 mg/day metformin and were compared with 10 untreated obese control subjects. Mutual information (MI) registration including spatial information has been shown to perform better than the traditional MI measures for certain nonrigid registration tasks. falciparum clinical isolate adapted to in vitro culture for a short period and characterized their protein content by mass spectrometry (data are available via ProteomeXchange, with identifier PXD006925). We bound a polydimethylsiloxane layer patterned with a microfluidic channel onto a well-defined nanoporous silica substrate. The amount spent on prevention in the low or average caries active group of adolescents during 4 years was less than half the sum spent in the high caries active group.

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This review is to summarize the advances in the chromosomal and genomic alterations of ESCC reported recently. Flow cytometric evaluation of skin biopsies for mycosis fungoides. Inhibitory effect of ferulic acid and isoferulic acid on murine interleukin-8 production in response to influenza virus infections in vitro and in vivo. We compared the effect of vitamin D on two cellular models: the primary human keratinocytes, differentiating and sensitive to the genomic action of VDR, and the human keratinocyte cell line HaCaT, characterized by a rapid growth and resistance to vitamin D. To our knowledge, this is the first case report of an asymptomatic non-functioning EPA in the suprasellar region treated by cranio-orbital skull base surgery. Differences in return to preinjury activity levels could not be determined due to the lack of studies assessing that outcome. These results suggest that BMP-2 plays an important role in nodule formation and acts synergistically with TGF-beta 1 to promote the nodules inductive cascade in the tracheal submucosa.

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