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Arpidox (Amitriptyline)

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Arpidox is an antidepressant medication that is sometimes prescribed off-label to manage chronic back pain. It is one of the drugs in a class of drugs known as tricyclic antidepressants. Arpidox is not a narcotic (opioid) drug, and there is not usually an addiction risk with the medication.

Other names for this medication:
Amicon, Amidez, Amiline, Amitar, Amitone, Amitop, Amitrim, Amitrix, Amitryn, Amitryptyline, Amoten, Amrea, Amsha, Amtipax, Arpidox, Axtrip, Bluneel, Chlotrip, Cotrip, Eliwel, Emotrip, Endep, Eptanol, Estiline, Gentrip, Latiln, Libotryp, Libral, Limbitrol, Lodep, Maxitrip, Mitrip, Mitryp, Psycomer, Relidep, Ronet, Tablin, Tadamit, Teedep, Tridep, Trixide, Tryline, Vanatrip

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Also known as: Amitriptyline


Arpidox target is the treatment of depression. Arpidox is acting by increasing the amounts of certain natural substances in the brain that are needed to maintain mental balance. It is tricyclic antidepressant. Generic name of Arpidox is Amitriptyline. Arpidox is also known as Amitriptyline, Amitryptyline, Amidon, Amitryn, Tryptanol, Endep, Elatrol, Tryptizol, Trepiline, Laroxyl, Saroten, Triptyl, Amitrip. Brand names of Arpidox are Arpidox, Endep, Vanatrip.


Usual Adult Dose for Depression:

OUTPATIENTS: -Initial dose: 75 mg orally per day in divided doses; this may be increased to 150 mg/day (if needed) -Maintenance dose: 40 to 100 mg orally per day -Maximum dose: 150 mg/day Alternate outpatient treatment regimen: 50 to 100 mg orally as a single dose at bedtime; this may be increased by 25 or 50 mg as needed at bedtime to a total of 150 mg/day INPATIENTS: -Initial dose: 100 mg orally per day -Maintenance dose: 40 to 100 mg orally as a single dose at bedtime -Maximum dose: 300 mg/day Comments: -Dose increases should preferably be made in the late afternoon or at bedtime due to the sedative effect. -The full therapeutic effect may take as long as 30 days to develop. -Maintenance doses should be reduced to the lowest amount that will maintain relief of symptoms when satisfactory improvement has been obtained. -Maintenance therapy should be continued for 3 months or longer to lessen the possibility of relapse. Use: Relief of symptoms of depression

Usual Geriatric Dose for Depression:

10 mg orally 3 times a day AND 20 mg orally once a day at bedtime Comments: -The full therapeutic effect may take as long as 30 days to develop. -Elderly patients should be monitored carefully and serum levels obtained as clinically appropriate. -Dose adjustments should be made according to clinical response. Use: Relief of symptoms of depression

Usual Pediatric Dose for Depression:

12 years or older: 10 mg orally 3 times a day AND 20 mg orally once a day at bedtime Comments: -The full therapeutic effect may take as long as 30 days to develop. -Dose adjustments should be made according to clinical response. Use: Relief of symptoms of depression

Detailed Arpidox dosage information


If you overdose Arpidox and you don't feel good you should visit your doctor or health care provider immediately. Symptoms of Arpidox overdosage: seizures, loss of consciousness for a period of time, seeing things or hearing voices that do not exist, agitation, feeling drowsy, rigid muscles, vomiting, high temperature, cold body temperature, problems concentrating, abnormal heartbeats, confusion.


Store at room temperature between 20 and 25 degrees C (68 and 77 degrees F) away from moisture and heat. Throw away any unused medicine after the expiration date. Keep out of the reach of children.

Side effects

The most common side effects associated with Arpidox are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.


Do not drink alcohol. Dangerous side effects or death can occur when alcohol is combined with amitriptyline.

Avoid driving or hazardous activity until you know how Arpidox will affect you. Your reactions could be impaired.

Avoid exposure to sunlight or tanning beds. Amitriptyline can make you sunburn more easily. Wear protective clothing and use sunscreen (SPF 30 or higher) when you are outdoors.

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Dynamics of kinks in one- and two-dimensional hyperbolic models with quasidiscrete nonlinearities. It is unclear if the use of insoles would prevent stress fractures in athletes. Modifications of the HD process to improve the hemodynamic tolerability of the treatment have been shown to reduce the perturbation of myocardial blood flow and functional evidence of dialysis-induced ischemia. Further studies reveal that the expression of mitogen-activated protein kinase phosphatase-1 (MKP-1) was induced by TNF-alpha, indicating that MKP-1 may be involved in protecting the cells from apoptosis by preventing a prolonged activation of JNK under normal conditions. Glycosphingolipids can be detected at concentrations as low as 5 pmol on the thin-layer chromatographic plate. They also had access to pond water that contained potentially toxic concentrations of the cyanobacteria (blue-green algae) Microcystis and Planktothrix spp. Since inflammatory regions were not observed in the skin of either type of transgenic mouse, our developmental system enables us to investigate constitutive capturing and trafficking of insoluble antigens in the steady state. The effects of the parental genetic background, different foreign sequences, and different insert sizes on growth characteristics were compared. A systematic review of the literature was undertaken to evaluate the incidence of lingual nerve damage after third molar surgery and the effect of a lingual retractor on nerve damage. We determined the presence, ontogeny and functionality of 11beta-HSD in the placenta and fetal, neonatal and adult kidney and colon in rats and rabbits and the cortisol:cortisone ratio in human amniotic fluid, which represents fetal urine.

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