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Arapres (Losartan)
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Arapres

Arapres slows the decrease of kidney function in patients with high blood pressure and type 2 diabetes. Arapres is a medication mainly used to treat high blood pressure. It's also used to treat patients with high blood pressure (hypertension) in adults and in children and adolescents 6 - 18 years of age.

Other names for this medication:
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Also known as: Losartan

Description

Arapres (losartan potassium) is an angiotensin II receptor blocker acting on the AT1 receptor subtype. Losartan potassium, a non-peptide molecule, is chemically described as 2-butyl-4-chloro-1-[p-(o-1Htetrazol- 5-ylphenyl)benzyl]imidazole-5-methanol monopotassium salt.

Arapres is a white to off-white free-flowing crystalline powder with a molecular weight of 461.01. It is freely soluble in water, soluble in alcohols, and slightly soluble in common organic solvents, such as acetonitrile and methyl ethyl ketone. Oxidation of the 5-hydroxymethyl group on the imidazole ring results in the active metabolite of losartan.

Arapres is available as tablets for oral administration containing either 25 mg, 50 mg or 100 mg of losartan potassium and the following inactive ingredients: microcrystalline cellulose, lactose hydrous, pregelatinized starch, magnesium stearate, hydroxypropyl cellulose, hypromellose, and titanium dioxide.

Arapres 25 mg, 50 mg and 100 mg tablets contain potassium in the following amounts: 2.12 mg (0.054 mEq), 4.24 mg (0.108 mEq) and 8.48 mg (0.216 mEq), respectively. Arapres 25 mg, Arapres 50 mg, and Arapres 100 mg may also contain carnauba wax.

Dosage

Take Arapres tablets orally with or without food. Do not crush or chew it. Take Arapres once or twice a day at the same time. If you want to achieve most effective results do not stop taking Arapres suddenly.

Overdose

Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.

Storage

Store at room temperature between 15 and 30 degrees C (59 and 86 degrees F) away from moisture, light and heat. Keep container tightly closed. Throw away any unused medicine after the expiration date. Keep out of the reach of children in a container that small children cannot open.

Side effects

The most common side effects associated with Arapres are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.

Contraindications

You should not use Arapres if you are allergic to losartan.

Do not use Arapres if you are pregnant, and tell your doctor right away if you become pregnant. Losartan can cause injury or death to the unborn baby if you take the medicine during your second or third trimester.

To make sure Arapres is safe for you, tell your doctor if you have:

kidney disease; liver disease; congestive heart failure; an electrolyte imbalance (such as high levels of potassium in your blood); if you are on a low-salt diet; or if you are dehydrated.

You should not breast-feed while using Arapres.

Arapres is not approved for use by anyone younger than 6 years old.

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Parenteral and enteral nutrition in the inoperable gastric cancer. Here we elucidated the role of tumour-intrinsic CDK20, or cell cycle-related kinase (CCRK) on immunosuppression in hepatocellular carcinoma (HCC). De-conjugation behavior of conjugated estrogens in the raw sewage, activated sludge and river water. The genomes are 2,199 and 2,211 nt-long, respectively, encoding a putative coat protein (CP) and a replication-associated protein (Rep) and showing a genomic organization typical of viruses from the family Genomoviridae. No significant difference between patients with schizophrenia and healthy participants with high symptom expression was found. Factors associated with the decline in suicide by pesticide poisoning in Taiwan: a time trend analysis, 1987-2010. These findings on functional A/D Env recombinants combined with structural models of Env suggest a conserved interplay between the C1 domain with C5 domain of gp120 and extracellular domain of gp41. The inhibitory effect of Zingiber corallinum Hance essential oil on drug-resistant bacteria and evaluation of its acute toxicity. Ease of counterfactual thought generation moderates the relationship between need for cognition and punitive responses to crime.

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Isotypic surveillance of anti-cardiolipin antibodies and high risk pregnancies. Measurements of sacral base angle, lumbar curve angle, and lumbosacral disc angle were compared with the values derived from the lumbar radiographs. Gold nanochains were prepared by the assembly of citrate-stabilized gold nanospheres induced by cationic conjugated polymers. RELEVANCE:--The results indicate that measures of centre of pressure excursion and ground reaction forces can differentiate between various mechanical and sensory conditions and thus are clinically useful for detecting and quantifying both mechanical and sensorimotor postural deficiencies. Before successful vaccines can be developed our knowledge of the initiation and implementation of host immunity must be improved. Functionalization of biomolecules on nanoparticles: specialized for antibacterial applications. Lethality in an anti-angiogenic tumor gene therapy model upon constitutive but not inducible expression of the soluble vascular endothelial growth factor receptor 1. We demonstrate for the first time a nanostructured planar photonic metamaterial transmitting light differently in forward and backward directions. This study thus captures the window for the miR-target correlation and the putative role of this regulation is discussed. A standardized pre-treatment method of biofilm flocs for fluorescence microscopic characterization.

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Video-assisted thoracic surgery lobectomy for lung cancer in a patient with complete situs inversus. Antidepressant-like activity was assessed using the tail suspension (TST) and the modified forced swimming tests (MFST). These results imply a more comprehensive role for UvrA, in addition to the recognition of DNA damage, in maintaining the integrity of the genome. The sialic acid of glycoproteins secreted by recombinant Chinese hamster ovary (rCHO) cells can be impaired by sialidase under culture conditions which promote the extracellular accumulation of this enzyme. The effect of cytostatic drug cyclophosphamide (CY) on lingual epithelium was studied in 90 female mice using histological, morphometric, quantitative histochemical and immunohistochemical methods. Thus, docetaxel combined with imatinib emerges as an attractive strategy for the treatment of ATC. Chitosan encapsulated quantum dots platform for leukemia detection.

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