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Anxrea (Clonazepam)

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Anxrea is one of the products that belong to the bensodiazepine group and have a strong sedative effect. Anxrea helps to stop convulsions and epileptic seizures. It is widely used among people with severe panic attacks and anxiety caused by depression treatment.

Other names for this medication:
Adnil, Almac, Alrest, Anxiset, Anxrea, Azpax, Cleps, Clodep, Clonark, Clonix, Clonoasig, Clonotril, Clopam, Closis, Clotas, Cloze, Clozep, Ection, Eminaz, Epcon, Epicloz, Epizam, Escimax, Escitacalm, Esitor, Jasoclam, Nazee, Nexclo, Norep, Nupam, Ozepam, Somnolex, Ubitpam, Zeficar, Zepamax, Zolpidox

Similar Products:
Buspar, Aldactone, Antivert, Sustiva, Zithromax, Pizolam, Maxolon, Enacard, Nevotek, Protopic,

Also known as: Clonazepam


Clonazepam is used alone or together with other medicines to treat certain seizure disorders (eg, Lennox-Gastaut syndrome, akinetic, myoclonic, and absence seizures). It is also used to treat panic disorder. Clonazepam is a benzodiazepine that works in the brain to prevent seizures. Benzodiazepines are central nervous system (CNS) depressants, which are medicines that slow down the nervous system.

This medicine is available only with your doctor's prescription.


Take this medication by mouth as directed by your doctor, usually 2 or 3 times daily.

Dosage is based on your medical condition, age, and response to treatment. For children, the dose is also based on weight. Older adults usually start with a lower dose to decrease the risk of side effects. Do not increase your dose, take it more often, or take it for a longer time than directed.

Take this medication regularly to get the most benefit from it. To help you remember, take it at the same times each day.

Do not stop taking this medication without consulting your doctor. Some conditions may become worse when this drug is suddenly stopped. Your dose may need to be gradually decreased.


Benzodiazepines like Anxrea became popular prescription medications, as alternatives to another class of anti-anxiety medications called barbiturates. Barbiturates were once very popular in the treatment of anxiety; however, they were highly addictive, carried a high risk for overdose, and were frequently abused. Benzodiazepines also carry a significant risk for the development of physical dependence and abuse (see below); however, they do not appear to carry the same risk of overdose that is associated with barbiturates (although overdose on benzodiazepines can occur).

Many of the cases of overdose that include benzodiazepines also include the co-occurring use of other drugs, such as alcohol, narcotic pain medications, or antidepressants. Using these drugs and benzodiazepines like Anxrea together enhances the effects of all drugs as well as increases the risk for overdose and potential fatalities due to drug interactions and drug overdose.


Store at room temperature away from light and moisture. Do not store in the bathroom. Keep all medications away from children and pets.

Do not flush medications down the toilet or pour them into a drain unless instructed to do so. Properly discard this product when it is expired or no longer needed. Consult your pharmacist or local waste disposal company.

Side effects

The most common side effects associated with Anxrea are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.


The elderly metabolize benzodiazepines more slowly than younger individuals and are also more sensitive to the effects of benzodiazepines, even at similar blood plasma levels. Doses for the elderly are recommended to be about half of that given to younger adults and are to be administered for no longer than two weeks. Long-acting benzodiazepines such as Anxrea are not generally recommended for the elderly due the risk of drug accumulation.

The elderly are especially susceptible to increased risk of harm from motor impairments and drug accumulation side effects. Benzodiazepines also require special precaution if used by individuals that may be pregnant, alcohol- or drug-dependent, or may have comorbid psychiatric disorders. Anxrea is generally not recommended for use in elderly people for insomnia due to its high potency relative to other benzodiazepines.

Anxrea is not recommended for use in those under 18. Use in very young children may be especially hazardous. Of anticonvulsant drugs, behavioural disturbances occur most frequently with Anxrea and phenobarbital.

Doses higher than 0.5–1 mg per day are associated with significant sedation. Anxrea may aggravate hepatic porphyria. Anxrea is not recommended for patients with chronic schizophrenia. A 1982 double-blinded, placebo-controlled study found Anxrea increases violent behavior in individuals with chronic schizophrenia.

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Fibronectin binding protein A of Staphylococcus aureus can mediate human T lymphocyte adhesion and coactivation. Patients with inguinal hernias should undergo screening for colon cancer at the same rate as the general population. In addition, soil fungal, bacterial, and nematode community composition and rotifer, collembolan, and mesostigmatid mite abundance differed among the tree species, while the total abundance of nematodes, tardigrades, oribatid mites, and prostigmatid mites did not. A pilot study of intermittent androgen deprivation in advanced prostate cancer. Purification and characterization of glutathione conjugate reductase: a component of the tetrachlorohydroquinone reductive dehalogenase system from Phanerochaete chrysosporium. tuberculosis induced HIV-1 expression in U1 cells, together with increased TNF-alpha production. The female meiotic spindle is commonly formed in a centrosome-independent manner. An experienced pulmonologist reviewed a random sample of 116 radiology transcripts, providing a reference standard for the natural language processing algorithm. Regulation of endothelial cell barrier function by calcium/calmodulin-dependent protein kinase II. No twins had current bulimia nervosa, and there was no difference in weight or eating status between the affected and unaffected twins.

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Ratings combining frequency and intensity dimensions of trauma-related nightmares decreased from 3.6 to 2.2, NNDA from 5.2 to 2.1, and sleep difficulty from 7.2 to 4.1 per week. These imaging features vary among clinical conditions, increase with longer postmortem time interval and must be distinguished from pathologic changes. An enzyme-linked immunosorbant assay kit was used for measuring PKC epsilon activity. Therapy techniques were introduced and practiced in a large group and small group format. Levodopa-induced complications in everyday life (UPDRS IV) and during an acute levodopa challenge had improved markedly after 1 year (both on and off stim) and still further at 5 years. The cell lines NIH:OVCAR-3, SK-OV-3, BG-1 and the primary ovarian tumor showed no proliferative response. Randomised clinical trials in perinatal health care: a cost-effective investment. To determine the applicability of the acceptance of lot quality assurance sampling (LQAS) in the primary care service portfolio, comparing its results with those given by classic evaluation. In conclusion, adrenalectomy modified maturation and the differentiation processes of the small intestinal mucosa, especially in the proximal part of the small intestine.

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Because of a lack of neonatal-specific information for levofloxacin, the usual pediatric dosage (10 mg/kg per dose every 12 hours) was used in these patients. Previous studies have examined the association between serum RBP4 concentrations and clinical indices in patients with type 2 diabetes, although the results obtained have been inconsistent. A small stone seen in the CBD was removed using a 6-Fr vascular Fogarty catheter. The efficacy of treatment of patients with severe constipation or recurrent pseudo-obstruction with pyridostigmine. All patients received CMV prophylaxis with valganciclovir for 3 months. In a careful double-blind procedure, neither the subjects nor the experimenters were made aware of the presence of the odors in the experimental conditions. A walk-through survey of an underground metalliferous mine and concentrator is used to demonstrate how the qualitative matrix can be applied to determine priorities for the control of occupational health hazards.

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Therefore, therapy for myeloma should be chosen not only on the basis of efficacy, but also taking into account their impact on the hematopoietic stem cell compartment. A risk strategy has been devised for people with diabetes regarding management during Ramadan fasting. These mutants are adaptive, with competitive fitness advantages on columns of 1.28-1.78. This study employs ordinary least squares (OLS) regression to estimate the significance of morality and economic policy variables on ART policies at the state level, noting associations between state-level political, economic, and gender variables on restrictive and permissive state-level ART policies. To evaluate the dosimetric differences between Superposition/Convolution (SC) and Monte Carlo (MC) calculated dose distributions for simultaneous integrated boost (SIB) prostate cancer intensity modulated radiotherapy (IMRT) compared to experimental (film) measurements and the implications for clinical treatments. Transformation-associated changes in gene expression of alternative splicing regulatory factors in mouse fibroblast cells. Substance P accelerates hypercellularity and angiogenesis in tendon tissue and enhances paratendinitis in response to Achilles tendon overuse in a tendinopathy model. Opioids produce reactive oxygen species (ROS) which are highly reactive molecules that damage cells and tissues, and are suggested to contribute to the opioid use disorders.

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Dietary supplementation with whey protein and ginseng extract counteracts oxidative stress and DNA damage in rats fed an aflatoxin-contaminated diet. A simulated annealing algorithm is used to exploit the design freedom. Tumor angiogenesis is associated with MUC1 overexpression and loss of prostate-specific antigen expression in prostate cancer. It was also possible to elicit a RAIR during the vesico-anal excitatory reflex. Database search revealed the sequence of the full-length form to be identical to that recently registered by D. The results are consistent with an interaction between band 3 and the Rh polypeptide-Rh glycoprotein (RhAG) complex, which may enhance translocation of the complex or affect its conformation in the plasma membrane. The experience of the International Society of Addiction Medicine in setting up the first international certification of clinical knowledge is reported.

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A survey containing items about social, demographic, and financial data was collected from ambulatory patients. PEGylated liposomes were found to be more mucosa-penetrating compared to other liposomes. Increased level of vascular endothelial growth factor in aqueous humor of patients with neovascular glaucoma. The development of software that can automatically yield meaningful values for hyperemia from hyperemia images will be a useful objective tool in clinical trials for evaluation of drug effects in animal models and in humans. The process of translation and cross-cultural adaptation followed the recommendations of international guidelines. The median external masculinization score (EMS) of this group was 9 (range 1-11). The data of 253 patients with ureter stones, who were treated with the Zeiss-loop were evaluated. A series of linearly linked perylenediimide (PDI) dimers and trimers were synthesized in which the PDI pi systems are nearly orthogonal. Randomised controlled trials of calcium supplementation or food fortification which include women of child bearing age not yet pregnant, or in early pregnancy.

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Allergic contact dermatitis from sodium pyrithione in metalworking fluid. Gallstone disease in the Far East exhibits a number of special features regarding epidemiology and etiology as well as indications for and response to surgical treatment. Proper haemostasis is an important prerequisite for a successful outcome in all operative fields. Increasing evidence suggests that the function of the vessel-protective factor Angiopoietin-1 (Ang-1), a ligand of the endothelial-specific Tie2 receptor, is inhibited by its antagonist Angiopoietin-2 (Ang-2) during sepsis. Conceptualizing biodiversity and ecosystems as goods and services that can be represented by monetary values in policy processes is an economic discourse being increasingly championed by ecologists and conservation biologists. Primary attention is given to the determination of trace impurities in biodiesel, such as methanol, glycerol, mono-, di-, and triacylglycerols, and sterol glucosides. We find, that the measured attenuation coefficients and refractive index decrements closely match calculated, theoretical values. Panax ginseng is one of the famous rare medicinal herbs, and ginsenosides are the main active ingredient of ginseng is ginsenoside.They can be divided into three chemotypes: oleanane type, protopanaxadiol (PPD) type and the protopanaxatriol (PPT)type. Long-term clinico-radiological assessment of endoscopic stapling of pharyngeal pouch: a series of cases. To investigate if parenting stress is associated with personal, and obstetric characteristics, the level of coparenting, and the availability of and satisfaction with social support in mothers of singletons and twins until one year postpartum.

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The upper gastrointestinal tract displays two different functional states: the interdigestive or fasting state, and the fed state. We characterized the dynamics of accumulation using high-throughput growth assays and competition experiments between virulent and avirulent (bvg(-) ) isolates. The principal candidate control agents studied include iridescent and nuclear polyhedrosis viruses, the bacteria Bacillus thuringiensis and Bacillus sphaericus, the fungi Lagenidium giganteum, Culicinomyces clavosporus, and species of the genus Coelomomyces, the protozoan Nosema algerae, and the mermithid nematode Romanomermis culicivorax. A clean intermittent catheterization program had failed in 12 patients and all 13 had diurnal incontinence. The sequestration of the steroid into the lysosomal/endosomal compartment indicates a potential substrate specificity for ABCA2. The root mean squared error of cross-validation values for the developed PLS models were 2.3, 1.0 and 4.4 mg Cl(-1), respectively, and the validation results where highly satisfactory (root mean squared error of prediction values of 1.8, 0.8 and 4.5 mg Cl(-1), respectively). Bronchiolitis obliterans syndrome: alloimmune-dependent and -independent injury with aberrant tissue remodeling. Molecular genetic analysis cost of compazine of a highly evolutionarily conserved Drosophila JNK homologue, DJNK, has demonstrated that this molecule plays an essential developmental role in cell shape regulation. Many short-lived nuclear proteins are targeted for degradation by the ubiquitin-proteasome pathway. Protein docking of ASPP2(ANK-SH3) and NFkappaB(p65), as well as molecular dynamics simulations of the proteins, provided structural models of the complex that are energetically similar to the NFkappaB-IkappaB determined structure.

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Behavioral results suggested that the drugs were interacting in the production of behaviors. Twenty right-handed participants made judgments about whether one of two bilaterally presented stimuli was an object/non-object or a tool/non-tool. Treatment of HIV-related tuberculosis in the era of effective antiretroviral therapy. The results of co-transfection experiments, transport assays, and the use of inhibitors suggest that PGPA recognizes metals conjugated to glutathione or trypanothione, a glutathione-spermidine conjugate present in Leishmania. Minimising iTRAQ ratio compression through understanding LC-MS elution dependence and high-resolution HILIC fractionation. This effect was apparently independent of changes in insulin resistance, in contrast to previous cross-sectional and cohort studies investigating the association between iron overload, insulin resistance and cardiovascular disease. The evaluation of these patients to determine their risk of sudden death and need for pacing is not well defined. The genomic regions targeted by RNAP V were small, with an estimated average length of neurontin max daily dose 238 bp. Second (control) group consistsed of patients-on term infants who had diagnosed one of developmental hip dysplasia, total of 75 (43 girls and 32 boys) during first exam in the Ultrasound unit of the Pediatric clinics in Sarajevo.

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Validation of an online questionnaire measure of the relative reinforcing value of food. The performance of powderblasted devices with integrated conductivity detection is illustrated by the separation of lithium, sodium, and potassium ions and that of fumaric, malic, and citric acid. The accurate measurement of it is important to both physiological research and medical application. The protein product of the HFE gene is a transmembrane glycoprotein, termed HFE, that modulates iron uptake. Acute and chronic changes in baroreflex sensitivity in hypobaric vs. One group of patients received 400 microg/day of beclomethasone dipropionate (BDP) for 4 weeks and then 800 microg/day for another 4 weeks (step-up group). Benzaldehyde dehydrogenase (BZDH) is encoded by the xylC that catalyzes the conversion of benzaldehyde into benzoate in many pathways such as toluene degradation. One of them showed chemical shift perturbations closely related to the natural ligands.

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To demonstrate, through our institutional series of intramedullary spinal tumor resection, the potential avoidance of dorsal column dysfunction after using dorsal column mapping. There were significant differences in testosterone, oestrone and progesterone levels and also reproductive history of patients who developed BCa compared with patients without BCa. The potential of the conjugate was checked by slit lamp evaluation of capsular opacification and by measuring crystallin synthesis. Raised osteoprotegerin appears to be an independent risk factor for total and CV death and thus has potential as a useful biomarker of risk as well as a potential target for therapeutic intervention. SE T1WI and FLAIR images were also acquired after gadolinium injection. Bartonella henselae, responsible of cat scratch disease, is to date the infectious agent most often encountered in adenitis. A Case of Complete Adult-Onset Kawasaki Disease: A Review of Pathogenesis and Classification. Further, the number of epidermal PGP 9.5-positive dendritic cells was increased in AD skin. One such error pattern concerned when participants make intrusions from prior lists: Rather than originating from random positions in the prior list, intrusions tend to be recalled in the same position as their position in the prior list, a finding which led to the endorsement of positional models of serial recall.

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The purpose of this study was to evaluate the most commonly applied criteria of IOPTH in patients undergoing MIP in a tertiary referral center. These changes, which would be induced by edema caused by high venous pressure, were especially prominent in the central area of the cords. In contrast amiloride brand name in philippines , renal blood flow was reduced by infusion of a nonselective NOS inhibitor or a high dose of a partially selective inducible nitric oxide synthase inhibitor. Head and Neck Squamous Cell Carcinomas Are Characterized by a Stable Immune Signature Within the Primary Tumor Over Time and Space. The survey was undertaken to identify and measure facility-level risk factors for violence, including staff perceptions of the quality of existing US Occupational Safety and Health Administration (OSHA) program elements, and ultimately to guide violence prevention programming. The first model is based on (1) the pro-inflammatory environment caused by ovulation events, (2) the expression pattern of ovarian inclusion cysts, and (3) biomarkers that are shared by the ovarian surface epithelium and malignant growth. The Au(111)/IL interfacial nanostructure in the presence of precursors and its influence on the electrodeposition process. Molecular diagnostic applications are now an integral part of the management algorithms of several solid tumors, such as breast, colon, and lung. In a previous study, we have shown that it is possible to create renal lesions in newborn mice specific to partial ureteral obstruction. Except for the radial-axial coupled vibration mode, the third longitudinal harmonic vibration mode with relative large vibration amplitude is also detected, which can be used as another operation mode.

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