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Anxilor (Lorazepam)

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Anxilor, an antianxiety agent, has the chemical formula, 7-chloro-5-(o-chlorophenyl)-1,3- dihydro-3-hydroxy-2H-1,4-benzodiazepin-2-one. It is a nearly white powder almost insoluble in water. Each Anxilor tablet, to be taken orally, contains 0.5 mg, 1 mg, or 2 mg of Anxilor. The inactive ingredients present are lactose monohydrate, magnesium stearate, microcrystalline cellulose, and polacrilin potassium.

Other names for this medication:
Almazine, Anxilor, Anxionil, Anxipose, Atipam, Biokalm, Biolar, Calmese, Dulozep, Larosh, Larpose, Lopam, Lopez, Loracalm, Lorakar, Loralite, Lorazam, Lorazepam, Lorazine, Loricon, Loripam, Lorivan, Lorpam, Lorvin, Lotweet, Nexlor, Norpose, Olraz, Trapex, Urpam, Zelor, Zepatrac, Zepnap

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Vermox, Nuvigil, Catapres, Zudena, Lexapro, Glyburide, Inderal, Priligy, Montlu, Imodep, Ppdom, Caltop, Dipyridamol, Levodel, Pedrox, Somaflam, Clomine,

Also known as: Lorazepam


Lorazepam is a benzodiazepine (ben-zoe-dye-AZE-eh-peen) that is used to treat a seizure emergency called status epilepticus. Lorazepam injection is also used as a sedative to help you relax before having surgery.


The Anxilor dosage your doctor prescribes will depend on several factors. These include:

  • the type and severity of the condition you’re using Anxilor to treat
  • your age
  • the form of Anxilor you take
  • other medical conditions you may have
Typically, your doctor will start you on a low dosage and adjust it over time to reach the dosage that’s right for you. They’ll ultimately prescribe the smallest dosage that provides the desired effect.

The following information describes dosages that are commonly used or recommended. However, be sure to take the dosage your doctor prescribes for you. Your doctor will determine the best dosage to suit your needs.

Drug forms and strengths

  • Tablet: 0.5 mg, 1 mg, 2 mg
  • Solution for injection (IV): 2 mg per mL, 4 mg per mL

General dosage information

The usual oral dosage for Anxilor tablets is 2 to 6 mg daily. This dosage amount is usually divided and taken two or three times daily.

Dosage for anxiety

Typical dosage: 1 to 3 mg taken two or three times daily.

Dosage for insomnia due to anxiety or stress

Typical dosage: 2 to 4 mg at bedtime.

Dosage for IV Anxilor

  • Intravenous (IV) Anxilor will be given by your doctor or nurse. Your doctor will determine the best dosage for your condition.

Special dosage considerations

Older adults and people with certain physical conditions may need to start with a lower dosage. This might be 1 to 2 mg, taken two or three times daily for anxiety or once at bedtime for insomnia.

What if I miss a dose?

If you miss a dose, take it as soon as you can. However, if it’s just a few hours until your next dose, skip the missed dose and take the next one on schedule.

Never try to catch up by taking two doses at a time. This can cause dangerous side effects.


Seek emergency medical attention if you think you have used too much of this medicine. An overdose of Anxilor can be fatal. Overdose symptoms may include extreme drowsiness, confusion, muscle weakness, fainting, or coma.


Store Ativan at room temperature away from moisture, heat, and light.

Keep track of the amount of medicine used from each new bottle. Anxilor is a drug of abuse and you should be aware if anyone is using your medicine improperly or without a prescription.

Side effects

The most common side effects associated with Anxilor are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.


Anxilor should be avoided in people with:

Sleep apnea – Sleep apnea may be worsened by Anxilor's central nervous system depressant effects. It may further reduce the patient's ability to protect his or her airway during sleep.

Myasthenia gravis – This condition is characterized by muscle weakness, so a muscle relaxant such as Anxilor may exacerbate symptoms.

Pregnancy and breast feeding – Anxilor belongs to the Food and Drug Administration (FDA) pregnancy category D, which means it is likely to cause harm to the developing baby, if taken during the first trimester of pregnancy. Evidence is inconclusive whether Anxilor, if taken early in pregnancy, results in reduced intelligence, neurodevelopmental problems, physical malformations in cardiac or facial structure, or other malformations in some newborns. Anxilor given to pregnant women antenatally may cause floppy infant syndrome in the neonate, or respiratory depression necessitating ventilation. Regular Anxilor use during late pregnancy (the third trimester), carries a definite risk of benzodiazepine withdrawal syndrome in the neonate. Neonatal benzodiazepine withdrawal may include hypotonia, reluctance to suck, apneic spells, cyanosis, and impaired metabolic responses to cold stress. Symptoms of floppy infant syndrome and the neonatal benzodiazepine withdrawal syndrome have been reported to persist from hours to months after birth. Anxilor may also inhibit fetal liver bilirubin glucuronidation, leading to neonatal jaundice. Anxilor is present in breast milk, so caution must be exercised about breast feeding.

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