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Anxidep (Imipramine)
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Anxidep

Anxidep, synthetic drug used in the treatment of depression and enuresis (bed-wetting). Anxidep was the first tricyclic antidepressant. Introduced into medicine in the late 1950s, Anxidep was the first tricyclic antidepressant, a class named for its three-ring molecular structure.

Other names for this medication:
Alzoset, Antidep, Anxitab, Anxofit, Depforte, Depnil, Depof, Depsin, Depsodep, Depsol, Depsolam, Diazariv, Eldep, Elidep, Endopax, Estidep, Finezol, Iminza, Imipramine, Impramine, Impranit, Imprim, Imprin, Karthin, Microdep, Nimipose, Talendep, Trydep, Ultradep

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Also known as: Imipramine

Description

Imipramine is used to treat depression. It belongs to a group of medicines known as tricyclic antidepressants (TCA). These medicines are thought to work by increasing the activity of a chemical called serotonin in the brain.

Imipramine tablets are also used to treat enuresis (bedwetting) in children.

This medicine is available only with your doctor's prescription.

Dosage

Take Generic Anxidep orally. Take Generic Anxidep with or without food. For adults The usual starting dose is 75 mg a day. The maximum daily dose is 200 mg. For children Total daily dosages for children should not exceed 2.5 mg for each 2.2 pounds of the child's weight. Doses usually begin at 25 mg per day. This amount should be taken an hour before bedtime. If needed, this dose may be increased after 1 week to 50 mg (ages 6 through 11) or 75 mg (ages 12 and up), taken in one dose at bedtime or divided into 2 doses, 1 taken at mid-afternoon and 1 at bedtime. Aged people The usual dosage should start with 25 to 50 mg per day. The dose may be increased as necessary, but effective dosages usually do not exceed 100 mg a day. If you want to achieve most effective results do not stop taking Generic Anxidep suddenly.

Overdose

Seek emergency medical attention or call the Poison Help line at 1-800-222-1222. An overdose of Anxidep can be fatal.

Overdose symptoms may include irregular heartbeats, feeling like you might pass out, seizures, or coma.

Storage

Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing.

Keep out of the reach of children.

Do not keep outdated medicine or medicine no longer needed.

Ask your healthcare professional how you should dispose of any medicine you do not use.

Detailed Anxidep-PM dosage information

Side effects

The most common side effects associated with Anxidep are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.

Contraindications

There are no adequate studies in women for determining infant risk when using this medication during breastfeeding. Weigh the potential benefits against the potential risks before taking this medication while breastfeeding.

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Bioelectric impedance spectroscopy was used to elucidate the influence of P-gp efflux pumps on the kinetics of tight junction down-regulation in confluent monolayers of Madine Darby Canine Kidney Epithelial Cells (MDCK) following administration of phenylarsine oxide (PAO), a molecule that inhibits protein tyrosine phosphatases (PTP) and induces matrix metalloproteinase activity. These results indicate that there is a close relationship between VEGF and MMP-9 expression and that inhibition of VEGF receptor down-regulates the expression of MMP-9. integrifolia significantly induced an increase in the percentage of entries into open arms and a decrease in percentage of entries into closed arms at the dose of 22 mg/kg BW. We assess how parental socioeconomic position (SEP) and education predict depression from late adolescence to early adulthood, a time of major educational transitions. Data on doe longevity in a rabbit population were analysed using a semiparametric log-Normal animal frailty model. In all cases, surface lipid was unusual in its selectivity for the insertion of the lipid probes.

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