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Antara (Fenofibrate)
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Antara

Antara is a fibric acid derivative like clofibrate and gemfibrozil. Antara is used to treat primary hypercholesterolemia, mixed dyslipidemia, severe hypertriglyceridemia. Antara was granted FDA approval on 31 December 1993.

Other names for this medication:
Apteor, Durafenat, Evothyl, Fenobeta, Fenobrat, Fenocap, Fenofibrate, Fenofibrato, Fenofibratum, Fenogal, Fenolid, Fenoratio, Fibrafen, Lifibrat, Lipanthyl, Lipidcare, Lipilfen, Lipirex, Lipofene, Lowlip, Minuslip, Normalip, Nubrex, Nuozhituo, Procetofen, Procetoken, Supralip, Trigent, Versamid, Xafenor

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Also known as: Fenofibrate

Description

Antara (fenofibrate) belongs to a group of drugs known as "fibrates." It helps reduce cholesterol and triglycerides (fatty acids) in the blood. High levels of these types of fat in the blood are associated with an increased risk of atherosclerosis (clogged arteries).

Antara is used along with a proper diet to help to treat high cholesterol and high triglyceride levels.

In addition to eating a proper diet (such as a low-cholesterol/low-fat diet), other lifestyle changes that may help Antara work better include exercising, losing weight if overweight, and stopping smoking.

Dosage

Usual Adult Dose of Antara for Hyperlipoproteinemia Type IIa (Elevated LDL): 145 mg orally once a day.

Usual Adult Dose for Hyperlipoproteinemia Type IIb (Elevated LDL + VLDL): 145 mg orally once a day.

Usual Adult Dose for Hyperlipoproteinemia Type IV (Elevated VLDL): 48 to 145 mg orally once a day. Usual Adult Dose for Hyperlipoproteinemia Type V (Elevated Chylomicrons + VLDL): 48 to 145 mg orally once a day. Usual Geriatric Dose of Antara for Hyperlipoproteinemia: 48 mg orally once a day. Increases in dosage should occur only after evaluating the effects on renal function and lipid levels at this dose, with a maximum recommended dose of 145 mg/24 hours.

Detailed Antara dosage information

Overdose

If you overdose Antara and you don't feel good you should visit your doctor or health care provider immediately.

Storage

Store at room temperature between 15 and 30 degrees C (59 and 86 degrees F) away from moisture and heat. Keep container tightly closed. Throw away any unused medicine after the expiration date. Keep out of the reach of children.

Side effects

The most common side effects associated with Antara are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.

Contraindications

You should not take Antara if you are allergic to fenofibrate, or if you have:

severe kidney disease (or if you are on dialysis); liver disease; or gallbladder disease.

Do not breast-feed while using this medicine, and for at least 5 days after your last dose.

To make sure Antara is safe for you, tell your doctor if you have ever had:

kidney disease; liver disease; or gallbladder problems.

Fenofibrate can cause the breakdown of muscle tissue, which can lead to kidney failure. This happens more often in women, in older adults, or people who have kidney disease, diabetes, or poorly controlled hypothyroidism (underactive thyroid).

It is not known whether this medicine will harm an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant.

Antara is not approved for use by anyone younger than 18 years old.

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A survey conducted by various locally organised cancer registries indicated breast cancer to be the most prevalent cancer among females and the second most common cause of cancer deaths among Pakistani women. Elucidating the molecular mechanisms that govern plant growth has been an important topic in plant research, and current advances in large-scale data generation call for computational tools that efficiently combine these different data sources to generate novel hypotheses. There are few studies in the literature from developing countries regarding the rates of catheter-associated urinary tract infection (CAUTI), which is frequently encountered in pediatric intensive care units (PICUs). Identification of Hsp90 as a species independent H5N1 avian influenza A virus PB2 interacting protein. Augmentation of soft tissue defects can be achieved through intradermal injection of silicone, animal collagen, plasma-gelatin mixture, and fat. Only the subgenus Eulandrevus of this genus, containing three species, has been recorded from China.

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There is a shortage of quality research into clinical outcomes of inpatient treatment, but controlled trials comparing hospital treatment with intensive community management are emerging. Distal migration was corrected by withdrawal of the catheter until an RV waveform reappeared at the RV port. The roles of apo(a) size, phenotype, and dominance pattern in PCSK9-inhibition-induced reduction in Lp(a) with alirocumab. Bacteriological comparison between combined and separate sewer discharges in southeastern Michigan. The depletion of PTTG1 in HCT116 colorectal cancer cells exhibited a cytotoxic effect in a p53-dependent manner. Both EPS compounds we identified can efficiently emulsify various oils (sunflower seed, diesel, and liquid paraffin) and hydrocarbons (toluene and hexane). Guidelines were formulated based on analysis of pertinent literature and consensus among authors. From algorithmic computing to direct retrieval: evidence from number and alphabetic arithmetic in children and adults.

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Comparative metabolic effect of continuous enteral nutrition and complete parenteral nutrition. Facial flushing response to alcohol and the risk of esophageal squamous cell carcinoma: A comprehensive systematic review and meta-analysis. In the sucrose preference test, both compounds significantly improved the reduced preference typically seen in susceptible mice at 3 to 7 days after a single dose of drug. Excess proinflammatory cytokines are removed by soluble cytokine receptors and receptor antagonists. Bronchopleural fistula is a serious complication of major lung resections that may lead to mortality. Using karyotypically defined cells and cell lines, we show that the number of signals obtained per nucleus correlates with the number of particular chromosomes present in that nucleus. After conducting a thorough investigation, SAGE found that the submitting authors of a number of papers published in the Journal of the Renin-Angiotensin Aldosterone System ( JRAAS) (listed below) had supplied fabricated contact details for their nominated reviewers. Using intraoperative catheter myelography, we corrected the position of the catheter. Many strategies have been utilized in an attempt to control the half-life of NO, including (but not limited to) lipid-based carriers, due to their biocompatibility and versatility.

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