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Antabuse (Disulfiram)

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Antabuse is a prescription medicine used to treat the symptoms of Alcoholism. Antabuse may be used alone or with other medications. Antabuse belongs to a class of drugs called Psychiatry Agents, Other.

Other names for this medication:
Chronol, Deadict, Diabuse, Disulfiram, Dulopam, Tyfusin, Ulfiram

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Also known as: Disulfiram


Antabuse (disulfiram) blocks an enzyme that is involved in processing alcohol. Disulfiram produces very unpleasant side effects (such as fast heartbeat, chest pain, nausea, dizziness, flushing, and thirst) when combined with alcohol in the body.

Antabuse is used in certain people with chronic alcoholism. This medicine can help keep you from drinking because of the unpleasant side effects that will occur if you consume alcohol while taking Antabuse.

Antabuse is used together with therapy and counseling support to help you stop drinking. This medicine is not a cure for alcoholism.


Do not take the first dose of Generic Antabuse for at least 12 hours after drinking alcohol. Take Generic Antabuse orally with or without food. If you want to achieve most effective results do not stop taking Generic Antabuse suddenly.


If you overdose Generic Antabuse and you don't feel good you should visit your doctor or health care provider immediately.


Store at room temperature between 20 and 25 degrees C (68 and 77 degrees F) away from moisture and heat. Keep in a tight light resistant container. Throw away any unused medicine after the expiration date. Keep out of the reach of children.

Side effects

The most common side effects associated with Antabuse are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.


Do not take Antabuse if you have consumed alcohol within the past 12 hours. Do not drink alcohol while taking disulfiram and for up to 14 days after you stop taking this medicine.

You should not use Antabuse if you are allergic to disulfiram, or if:

you have recently taken metronidazole (Flagyl) or paraldehyde; you have consumed any foods or products that contain alcohol (mouthwash, cough medicine, cooking wine or vinegar, certain desserts, and others). you have severe heart disease or blockage in the arteries of your heart; or you have been diagnosed with psychosis.

To make sure Antabuse is safe for you, tell your doctor if you have:

liver or kidney disease; heart disease, high blood pressure, history of heart attack or stroke; underactive thyroid; diabetes; seizures or epilepsy; head injury or brain damage; mental illness; an allergy to rubber; or if you take phenytoin (Dilantin), tuberculosis medicine, or a blood thinner (warfarin, Coumadin, Jantoven).

It is not known whether Antabuse will harm an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant while using this medicine.

It is not known whether Antabuse passes into breast milk or if it could harm a nursing baby. You should not breast-feed while using this medicine.

Do not give this medicine to anyone under 18 years old without medical advice.

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Intravenous insulin improves clinical outcome in patients hospitalized in intensive care units. Clinical profile of HIV/AIDS-infected patients admitted to a new specialist unit in Dhaka, Bangladesh--a low-prevalence country for HIV. In the present study, we determined the expression and subcellular localization of centrobin in selected mouse tissues. Hyperlipidemia modulates the expression of multiple genes, however, and the effects of PAI-1 on the arterial response to injury under hyperlipidemic conditions are unknown. Insight into molecular and functional diversity of tachykinins and their receptors. Aberrant respiratory sensitivity to CO(2) as a trait of familial panic disorder. Enhancement of MSH receptor- and GAL4-mediated gene transfer by switching the nuclear import pathway. However, the baseline urinary excretion of 8-OHdG before exercise tended to be lower after beta-carotene supplementation.

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Centchroman regresses mastalgia: a randomized comparison with danazol. Modes and cuts in metabolic networks: complexity and algorithms. Experimental results show that the proposed method can achieve the optimal layout for distributed storage in the process of disaster data retrieval in the China Sea area, and effectively optimize the result of partitions when new buoys are deployed, which eventually will provide efficient data access service for marine events. Indomethacin interferes with EGF-induced activation of ornithine decarboxylase in gastric cancer cells. In experiments which compared both, bi-specifics which included a target for clusterin had inhibitory activity similar to the previously described bi-specifics directed towards bcl-2 and EGFR. Identification of proteins from Escherichia coli using two-dimensional semi-preparative electrophoresis and mass spectrometry. Two new subgroups and a new group were identified from the Chinese isolates in p25 and p26 trees, respectively. The activation of Akt and MAPK in parallel pathways downstream from PI3K resulted in the phosphorylation of Bad at different serine residues. A leiomyosarcoma was diagnosed that originated in the right lateral ventricle wall, causing pulmonary outflow obstruction. Additive inhibitory effects of retinoids and interferon-alpha on the growth of human cervical carcinoma cells.

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The current hiatus in occupational injury research in Australia. In order to fully explore and utilize the advantages of droplet-based microfluidics, fast, sensitive, and quantitative measurements are indispensable for the diagnosis of biochemical reactions in microdroplets. Calcium (Ca) bridges or viscous binding by UM could explain this AGN. Southern blotting and plasmid rescue analyses show that the introduced exogenous DNA was integrated at random into the parasite genome. Group unity of chimpanzees elucidated by comparison of sex differences in short-range interactions in Mahale Mountains National Park, Tanzania. Within lymph nodes, T and B lymphocytes migrate along networks of fibroblastic reticular cells and follicular dendritic, respectively, which provide an adhesive platform and solid phased chemokines. The reported case was classified into class 1 lesions, which are associated with low mortality and good prognosis. However, invariance testing indicated that the relationships between these variables were not different across groups. Both IL-17A and IL-17F are induced by similar stimuli, have similar expression kinetics and despite only minimal in vitro activity for IL-17F, surprisingly they exert similar in vivo bioactivity. However, the high-speed rotations of the motors under low-load conditions were still significantly impaired, suggesting that the rate of proton translocation is still severely limited at high speed.

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CTA is currently widely considered the standard, due to its high accuracy and reliability. To examine the proximal signaling processes mediated by the pre-TCR complex and the role of the TCR-zeta chain in these processes, we stimulated pre-TCR-expressing cells and analyzed the interactions of the TCR/CD3 invariant chains with the Syk/ZAP-70 family of protein tyrosine kinases. We conducted a community-based cross-sectional study including 1083 healthy subjects (323 men and 760 women) in an urban biaxin oral suspension area. Herein we report a several-fold increase in the efficacy of such CPPs if the linear flexible spacer (-X-) in the (R-X-R) motif is replaced by constrained cyclic 1,4-substituted-cyclohexane-derived spacers. Here we report a molecular study of the JT involving 1q21 found in a patient with acute myelomonocytic leukemia that had transformed from myelodysplastic syndrome (MDS). Here we report two cases that illustrate the difficulty in distinguishing between primary and secondary cutaneous involvement. Recognition of the toxin by the anti-alpha-bungarotoxin single chain Fv was very similar to that of the receptor, such as indicated by the epitope mapping of alpha-bungarotoxin through overlapping synthetic peptides.

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B lymphocytes express Ag receptors (BCR) that are composed of ligand binding subunits, the membrane Igs, associated with Ig alpha/Ig beta heterodimers. Vaginal adenosis with adenocarcinoma in situ in a woman with no recognised antecedent factors. Walking speed was measured by timed 8-ft (2.44 m) test in 6,345 individuals, with mean age of 61.1 (SD 6.0) years. Many of the strains produced patulin and/or citrinin, often depending on whether they were grown on a grape or yeast extract sucrose media. These observations suggested that IdaA protein, a previously described negative factor for DnaA protein, inactivated DnaA protein through stimulation of the hydrolysis of ATP bound to DnaA protein. verrucosa were distinct from those of other dematiaceous fungi including Exophiala jeanselmei, E. To describe the association between obesity and the use of antipsychotic drugs (APDs) in adult outpatients followed-up on in five Primary Care settings.

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