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Anfuramide (Furosemide)
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Anfuramide

Anfuramide is a type of medicine called a diuretic. It's used to treat high blood pressure, heart failure and oedema (a build up of fluid in the body). It's also sometimes used to help you pee when your kidneys aren't working properly. Diuretics are sometimes called "water pills/tablets" because they make you pee more.

Other names for this medication:
Aldalix, Anfuramide, Ansemid, Betasemid, Foliront, Frusemide, Frusenex, Furantral, Furesis, Furetic, Furide, Furocot, Furosemide, Furovet, Furoxem, Furozenol, Fursemid, Furtenk, Fusix, Inclens, Intermed, Jufurix, Lasilacton, Lasilactone, Lasiletten, Lasilix, Salix, Vesix

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Also known as: Furosemide

Description

Anfuramide prevents excessive edema (fluid retention) in people with kidney disorder (nephrotic syndrome), heart failure, cirrhosis and liver disease. It is also used for the treatment of high blood pressure (hypertension), high levels of potassium (hyperkalemia), calcium (hypercalcemia), and magnesium (hypermagnesemia). The active component, Furosemide, is a potent loop diuretic (water pill) that eliminates water and salt from the body. Furosemide works by blocking the absorption of sodium, chloride, and water from the filtered fluid in the kidney tubules, causing a profound increase in the output of urine (diuresis). Anfuramide starts to act within one hour after oral administration, and the effect lasts for about 6-8 hours.

Dosage

Infants and Children. The usual initial dose of oral Lasix for infants and children is 2mg/kg body weight given as a single dose. If the diuretic response is not satisfactory, the dose may be increased by 1 to 2 mg/kg no sooner than 6 to 8 hours after the previous dose. Doses of greater than 6 mg/kg body weight are not recommended.

For maintenance therapy in infants and children, the dose should be adjusted to the minimum effective level.

Lasix Oral Solution is filled under nitrogen. Use within 3 weeks of opening bottle.

Overdose

In case of a Anfuramide overdose visit your doctor or health care provider immediately. Symptoms of a Anfuramide overdose include fainting, tinnitus, confusion, weakness, lightheadedness, lack of appetite.

Storage

Keep this medicine in the container it came in, tightly closed, and out of reach of children. Store it at room temperature and away from excess heat and moisture (not in the bathroom). Throw away unused furosemide solution after 90 days. Throw away any medicine that is outdated or no longer needed. Talk to your pharmacist about the proper disposal of your medicine.

Side effects

The most common side effects associated with Anfuramide are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.

Contraindications

Known hypersensitivity to frusemide or sulfonamides or any of the inactive ingredients. Patients allergic to sulfonamides (e.g. sulfonamide antibiotics or sulfonylureas) may show cross-sensitivity to Lasix.

Complete renal shutdown; impaired renal function or anuria. If increasing azotaemia and oliguria occur during treatment of severe progressive renal disease, discontinue frusemide. Severe hypokalaemia, hyponatraemia, hypovolaemia, dehydration or hypotension must be regarded as contraindications until serum electrolytes, fluid balance and blood pressure have been restored to normal levels.

In hepatic coma or precoma and conditions producing electrolyte depletion, frusemide therapy should not be instituted until the underlying conditions have been corrected or ameliorated. In breast-feeding or pregnant women.

Do not administer frusemide to newborns presenting jaundice or to infants with conditions which might induce hyperbilirubinaemia or kernicterus (e.g. Rhesus incompatibility, familial non- haemolytic jaundice etc.) because of frusemide's in vitro potential to displace bilirubin from albumin.

Lasix 250 mg injection must not be used as a bolus injection. It must only be infused using volume or rate controlled infusion pumps to reduce the risk of accidental overdose.

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