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Amlodipine is used to treat high blood pressure. Everyone has blood pressure. This pressure helps to circulate the blood all around your body. Your blood pressure may be different at different times of the day, depending on how busy or worried you are. You have hypertension (high blood pressure) when your blood pressure stays higher than is needed, even when you are calm and relaxed.

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Amlodipine (amlodipine) is a calcium channel blocker that dilates (widens) blood vessels and improves blood flow.

Amlodipine is used to treat chest pain (angina) and other conditions caused by coronary artery disease.

Amlodipine is also used to treat high blood pressure (hypertension). Lowering blood pressure may lower your risk of a stroke or heart attack.

Amlodipine is for use in adults and children who are at least 6 years old.


Take Amlodipine exactly as prescribed by your doctor. Follow all directions on your prescription label. Your doctor may occasionally change your dose. Do not use this medicine in larger or smaller amounts or for longer than recommended.

You may take Amlodipine with or without food. Take the medicine at the same time each day.

Your blood pressure will need to be checked often.

Your chest pain may become worse when you first start taking Amlodipine or when your dose is increased. Call your doctor if your chest pain is severe or ongoing.

If you are being treated for high blood pressure, keep using Amlodipine even if you feel well. High blood pressure often has no symptoms. You may need to use blood pressure medicine for the rest of your life.

Your hypertension or heart condition may be treated with a combination of drugs. Use all medications as directed by your doctor. Read the medication guide or patient instructions provided with each medication. Do not change your doses or stop taking any of your medications without your doctor's advice. This is especially important if you also take nitroglycerin.

Amlodipine is only part of a complete program of treatment that may also include diet, exercise, weight control, and other medications. Follow your diet, medication, and exercise routines very closely.

Store at room temperature away from moisture, heat, and light.

Detailed Amlodipine dosage information


If you overdose Amlodipine and you don't feel good you should visit your doctor or health care provider immediately. Symptoms of Amlodipine overdosage: fainting, dizziness, rapid heartbeat.


Store at room temperature between 15 and 30 degrees C (59 and 86 degrees F) away from moisture, light and heat. Keep container tightly closed. Throw away any unused medicine after the expiration date. Keep out of the reach of children in a container that small children cannot open.

Side effects

The most common side effects associated with Amlodipine are:

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Avoid getting up too fast from a sitting or lying position, or you may feel dizzy. Get up slowly and steady yourself to prevent a fall.

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Depression adversely affects the mental and physical health, and the social and financial welfare of the individual and society. Parameters for ventricular function and exercise were compared for both groups with controls. The holographic nature of the reconstruction method allowed significantly better estimation of the fine spatiotemporal detail of neuronal population activity, compared with interpolation alone, beyond the spatial resolution of the electrode arrays used. To assess the diagnostic accuracy of adjunct methods used to detect and quantify dental caries. In addition, we observed a markedly reduced frequency of slanDCs in the blood of patients with bacterial infection, CMV reactivation, or severe acute GvHD.

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Additional assessments will be completed at post-treatment and 6-month follow-up. Erroneous criteria were a large size (4 cases), and a mass that was not purely fatty. In a small-scale feasibility study, consecutive patients admitted to an acute stroke ward were screened for eligibility. A single-center, randomized, double-blind, placebo-controlled trial with SLIT was conducted. Treatment guidelines for juvenile arthritis, including JSpA, were published by the American College of Rheumatology and are based on active joint count and presence of sacroiliitis.

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Accidental epinephrine auto-injector-induced digital ischemia reversed by phentolamine digital block. Basal MAPK activity partially correlated with basal VEGF promoter activity and VEGF protein levels in primary astrocytes, T9 and RT2 cells. The cells had individual discharge patterns at successive stages of behavior. Antenatal clinic HIV sentinel surveillance sites in sub-Saharan Africa increased from just over 1000 in 2003-2004 to almost 2500 in 2005-2006, becoming more representative of rural areas. This emerging field intimately correlates with the topics of rechargeable batteries, nanomaterials, on-chip microfabrication, etc. An experiment was conducted to evaluate indices of fertility including the sperm penetration (SP) assay as a technique for the prediction of fertility. The multi-task filter was evaluated on microarray data related to nine different types of cancers. The efficiency of AZT efflux increased in the distal ileum as consequence of exposure to AZT, with the amount of drug permeating from the mucosal to the serosal side diminishing after 35 min. Two different surface chemical compositions of AgNPs, polysaccharide-coated and hydrocarbon-coated, were used to test their toxic effects on self-renewal and proliferation of mESCs. Moreover UVA is implicated in the etiology of several photodermatoses.

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Oxazolidinone antibiotics are active against many Gram-positive bacteria, but are inactive against P. Further studies will focus on combining anti-sclerostin therapy with tumor-targeted agents to achieve both beneficial skeletal outcomes and inhibition of tumor progression. Data will be transferred electronically by hospital and regional coordinators and managed at the Data Management Unit of CRRH, Sagamu, Nigeria. The mechanisms might be attributed to its anti-oxidative properties and NO-cGMP signaling pathway upregulation. The focus on quality of life issues in wound care has justly taken a far greater importance.

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To describe follow-up and evaluate functional results of rigid gas-permeable contact lens wear for the correction of aphakia in infants after surgery for congenital cataract. Linear regression analysis was used in unadjusted and two adjusted (accounting for prediabetes/diabetes, body mass index, smoking, and other covariates) statistical models. During the study period, 20 CMT patients underwent complete tight fibrous band release and resection. The Yucheng children scored lower than control children on each of these methods of measurement between the ages of 2 and 12 years. Both tumors shrank significantly, but the patient died from progressive systemic cancer 1 year after diagnosis of brain metastasis. Prospectively, two-dimensional (2D) time-of-flight (TOF) and 3D gadolinium-enhanced MR angiography was performed in 23 patients. Relationship between glutathione S-transferase M1, P1 and T1 polymorphisms and early onset prostate cancer. Wear patterns on the tibial surface show that the areas involved in the majority of cases include middle medial and middle lateral regions of the tibial plateau.

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The results suggest that cholesterol-induced steatosis leads to a weakened antioxidant defence system and causes peroxidation in the hepatic tissue. Possibility of preventing wound contamination by use of special scrub suits. traits and facets) and how they can predict important consequential outcomes. Circulating aldosterone concentrations were inappropriately low and complicate the profound electrolyte deficiencies resulting from chronic diarrhoea. After the injury, muscle tonus of the limbs and trunk diminished. Fibrinogen/LDL apheresis for treatment of sudden hearing loss: an observational study on 152 patients. Implementation of technological advancements in green chemistry approaches can minimize the deviation retaining maximum qualitative properties in environment friendly way. The Dahlak sponge was found to be richer in the more polar triterpenes. In the selection of an endodontic post, its stability rather than its retention should be of primary clinical concern. The Archaea (archaebacteria) constitute a group of prokaryotes that are phylogenetically distinct from Eucarya (eukaryotes) and Bacteria (eubacteria).

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Severe irreversible optic neuritis following Mantoux tuberculin skin test in a child with multiple sclerosis--a case report. Src protein-tyrosine kinase is a potent inducer of invadopodia and tumor metastases. By enzyme-linked immunoelectrotransfer blot, Bancroftian filariasis sera gave specific reactions with glycoprotein ES antigens at MW 20.5 kDa against anti-human IgG. Postburn deformity of lip-chin complex: a method to restore the mentolabial sulcus. To evaluate an alternative pharmacological method of baroreflex testing, which might provide more comprehensive evaluation of the baroreflex function in patients with uncomplicated myocardial infarction. Future studies will focus on characterization of SLA-haplotypes associated with these particular alleles and the dynamics of the immune response to antigenic challenges. Reoptimized interaction parameters for the peptide-backbone model compound N-methylacetamide in the GROMOS force field: influence on the folding properties of two beta-peptides in methanol. Plasma quinine concentrations were measured by high-performance liquid chromatography (HPLC) and the 24-h urinary sodium excretion was assayed.

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More interestingly, within the cytotoxic RNase derivatives, cytotoxicity correlated well with the net positive charge. Exercise like a hunter-gatherer: a prescription for organic physical fitness. Hypertonic treatment (0.5 M NaCl in phosphate-buffered saline, pH 7.2) at 37 degrees C for 20 min slightly delayed the mitotic frequency for non-irradiated cells in G1 and G2 phases. In order to meet the legislation by the end of 2015, each business needs to install an individual waste water treatment system (IWTS). Linkage of infantile Bartter syndrome with sensorineural deafness to chromosome 1p. The first data level, onto which each module is based, is a 2DE proteomic reference map where proteins separated by 2D electrophoresis, and subsequently identified by mass-spectrometry, are marked.

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The analysis of the Hex and Hesx1 mutant mice has revealed that the lack of these genes has little or no effect on the early steps of anterior neural induction. Imaging and treatment of scaphoid fractures and their complications. Periodicity of polar and nonpolar amino acids is the major determinant of secondary structure in self-assembling oligomeric peptides. Factor structure and validity of the State-Trait Inventory for Cognitive and Somatic Anxiety. We aimed to conduct a meta-analysis to compare these two drugs in patients with brain injury. Pruritus rapidly resolved on removal of the tumor and recurred on reappearance. Although the results obtained depend on the database absolutely, recombination of existing knowledge in this method provides new insight for interpreting the molecular mechanism of TCM. Research using VR has shown that drug-dependent people react with strong craving to specific cues (e.g., cigarette packs, liquor bottles) as well as environments or settings (e.g., bar, party) associated with drug use.

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Analysis of the performance, emission and combustion characteristics of a turbocharged diesel engine fuelled with Jatropha curcas biodiesel-diesel blends using kernel-based extreme learning machine. cDNA cloning and protein analysis of a bovine dermal allergen with homology to psoriasin. Esculentin 1-21: a linear antimicrobial peptide from frog skin with inhibitory effect on bovine mastitis-causing bacteria. Pre-post measures were collected through self-report via the program website. The retinoid X receptor (RXR) activates transcription of target genes in response to its natural ligand, 9-cis retinoic acid (9cRA), and a number of RXR-specific synthetic ligands. Mantle cell lymphoma: presenting features, response to therapy, and prognostic factors.

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The Escherichia coli protein DbpA is unique in its subclass of DEAD box RNA helicases, because it possesses ATPase-specific activity toward the peptidyl transferase center in 23S rRNA. A pooled analysis was conducted on data obtained from the integrated safety database of edivoxetine as adjunctive treatment to SSRIs. In this study, we used a T cell-dependent model of autoimmunity, experimental autoimmune uveitis (EAU) to address this issue. Synthesis and evaluation of amino acid-based radiotracer 99mTc-N4-AMT for breast cancer imaging. It is from these dramatic genomic alterations, and selection on their phenotypic consequences, that adaptations leading to biological diversification could be derived. Using a Cre transgene driven by the common alpha subunit of glycoprotein hormones (alphaGSU-Cre), we have previously inactivated steroidogenic factor 1 (SF-1) in the anterior pituitary, causing hypogonadotropic hypogonadism with sexual infantilism, sterility, and severe gonadal hypoplasia.

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Results are discussed in terms of potential sociocultural and neurobiological influences on brain organization, development of cognitive abilities, and potential for cultural bias when evaluating ethnic minority children. Rehabilitation procedures must aim at restoring as many binaural advantages as possible. The previous sulcal extraction methods are time-consuming in practice and often have a difficulty to delineate curves correctly along the sulcal regions in the presence of significant noise. Clinical impact of endoscopic ultrasound-guided fine needle aspiration biopsy in patients with upper gastrointestinal tract malignancies. Links between resources, C metabolism and the major components of bacterioplankton community structure across a range of freshwater ecosystems. Meta-analyses to examine the effects and meta-regression analyses to investigate correlations between the effects and birthweight, duration of the care, environmental temperature, and resources of the setting, were conducted.

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Complete Genome Sequence of Ureibacillus thermosphaericus A1, a Thermophilic Bacillus Isolated from Compost. Our AABB immunohematology reference laboratory (IRL) conducted a study to determine which antibody identification testing method was optimal for detecting all clinically significant antibodies. As it did in wild-type cells, G-Rh2 induced the proteolytic activation of caspase-3 protease and subsequent cleavage of PARP in the bcl-2 transfectants. The GDG constructed a CPG for non-specific LBP along with point-of-care decision-support and patient-education tools. To investigate the expression of eNOS and iNOS mRNA and protein in adipose tissue from subcutaneous (s.c.) and omental adipose tissue of obese subjects. The experimental solubility data have been correlated by means of three commonly known G(E) equations: the Wilson, NRTL, and UNIQUAC, with the assumption that the systems studied here have revealed simple eutectic mixtures. The electrocardiogram after successful defibrillation showed inverted T waves in the chest leads with long QT intervals, and subsequent emergent coronary catherization revealed the recurrence of ampulla cardiomyopathy. Eruption status of third molar and its possible influence on the location of mandibular angle fracture: a retrospective analysis. METH-ODS: The human foreskin acellular matrix graft was prepared, its safety and biocompatibility as urethral material were determined by histological observation, cytotoxicity test using primary epithelial cells and experiment in vivo. Naringenin and quinidine, which are inhibitors of some isozymes of cytochrome P450 and are not known to be extensively metabolized, showed no major metabolites.

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Perspectives of Stakeholders on Implementing a Farm-to-University Program at an HBCU. This might have important consequences for other recurrent OC trials. Erythrocyte selenium and SePP were markedly lower both in the clinical and proven sepsis groups versus control. A discussion of the human literature is presented here, which largely consists of experimental studies in healthy human control subjects. A large proportion of patients (24) had experienced a rapidly fluctuating clinical course prior to the time of suicide. Doubly negative metamaterials in the near infrared and visible regimes based on thin film nanocomposites. Intraoperative OCT may facilitate the transition for novice DMEK surgeons by increasing surgeon confidence and reducing the risk of iatrogenic graft failure. We used a data extraction tool in Microsoft Excel to manage searches and document reasons for inclusion and exclusion, and to extract descriptive and numerical data from trials meeting the inclusion criteria.The prespecified primary is it safe to drink alcohol while on lexapro outcomes were exacerbations requiring oral steroids, asthma control, and all-cause serious adverse events. Re-expression of SSeCKS in v-Jun-transformed fibroblasts reversed the transformed phenotype of the cells.

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Subjective visual examination of a single cephalogram may result in false-positive findings of fusion and growth-based superimposition is recommended. This study demonstrates the potential application of the HH2-CpG complex as a vaccine adjuvant. Ray Lyman Wilbur and the then Governor of California, Earl Warren). Total cystectomy is the ideal surgery, if not possible or at high risk, partial pericystectomy is acceptable. Experimental preemptive immunotherapy of murine cytomegalovirus disease with CD8 T-cell lines specific for ppM83 and pM84, the two homologs of human cytomegalovirus tegument protein ppUL83 (pp65). Brain water content and Evans blue content were less in estrogen-treated group comparison to vehicle group. Few studies have examined the association of physically loading work with sciatica, and studies concerning women are scarce. Yet it is largely unknown whether such programmes actually help population size recovery. It may be that the size of the lesion is of major importance in its progressive potential.

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The wafers contain poly(lactic-co-glycolic acid) as the main bioerodible component used in the bulk layer and ethyl cellulose applied as a matrix polymer enabling diffusion-controlled release. Leveraging the IncuCyte Technology for Higher-Throughput and Automated Chemotaxis Assays for Target Validation and Compound Characterization. Cardiac metastases from renal cell carcinoma are extremely rare. Immune reconstitution uveitis complicated by vitreoretinal traction and formation of a retinal tear. The EPO protein secreted from hiPSC-derived EPO-producing (hiPSC-EPO) cells induced the erythropoietic differentiation of human umbilical cord blood progenitor cells in vitro. The detection of type-specific antibody by s-CRN antibody assay may be useful when attempting to analyze human HSV infection. Recent studies have suggested that craniotomy with the goal of cytoreduction might be associated with a favorable overall and progression-free survival for some patients with PCNSL. Congenital heart diseases are traditionally considered to be multifactorial in pathogenesis resulting from environmental and genetic interactions that determine penetrance and expressivity within a genetically predisposed family. We hypothesized that the integration of forensic psychiatrists and the forensic system into the general stream of mental health should lead to better reintegration of forensic patients into the society. Sigmoid diverticulosis--a risk factor for perforation of the sigmoid colon due to ipilimumab-associated enterocolitis?.

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EMX1 and yeast endonuclease X3 were also found to be sensitive to anti-(endonuclease VII) antibodies which inhibited their reactions with cruciform DNAs in vitro. Microsatellite instability was ruled out by the allelic pattern of two major mononucleotide repeats. The Goto-Kakisaki (GK) rat is a genetic model of non-insulin-dependent diabetes. The study revealed the potential to produce milk with a distinct composition and sensory quality based on even small changes in the feed composition that are straightforward to implement by para que sirve la neurontin 300 mg farmers. Both lowland and upland cultivars were grown under excess Fe and hypoxic conditions. Characterization of immunoreactive adrenomedullin in human plasma and urine.

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Multiple transcriptional events take place when normal urothelium is transformed into tumor tissue. Our results demonstrated that yawning is a common self-reported symptom leading or accompanying migraine attacks and is associated with aura, nausea and/or vomiting, osmophobia, and cutaneous allodynia in patients with migraine. The release mechanism of ketoprofen from two gel devices showed an anomalous (non-Fickian) transport, in which the release of ketoprofen with a low water-solubility could be directly related to the rapid release of water accompanying a gel shrinkage. Indomethacin significantly inhibited the acid-induced HCO3- secretion as well as the PGE2 biosynthetic response, without influence on the NOx release. Plasma TARC levels should be measured in platelet-free plasma for accurate quantitation. The patient denied the self-induced nature of the lesions, so she was referred for psychiatric evaluation and admitted having self-injected mineral oil as an impulsive attempt to get attention from her family. Between September 2000 and June 2008, 36 patients with ampullary tumors confined to the mucosa and no intraductal tumor growth underwent ESP.

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While Notch signaling plays essential roles in regulating the morphogenesis of the node and left-specific expression of Nodal in the lateral plate mesoderm, a hallmark gene in LR patterning, Notch signaling also suppresses the expression of Pitx2 that is a direct downstream target of Nodal during later stages of development. 2H-Dinaphthopentacene: A Polycyclic Aromatic Hydrocarbon Core for Metal-Free Organic Sensitizers in Efficient Dye-Sensitized Solar Cells. Long-term leptin treatment of ob/ob mice improves glucose-induced insulin secretion. Phytobarriers: Plants capture particles containing potentially toxic elements originating from mine tailings in semiarid regions. AgNPs were visibly and spectroscopically identified which were spherical with the size range of less than 20 nm. Our objective was to design a transfusion practice nursing survey to study the causes of the increasing mistransfusion rate.

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This study examined trends in the images of norvasc 5 mg presentation, recognition and recording of anxiety and of anxiolytic and hypnotic prescriptions for CYP in primary care. To fill up this gap, we attempted to differentiate human MSC into EC, by culturing the former onto chemically fixed layers of EC or its ECM, respectively. Pictionary-based fMRI paradigm to study the neural correlates of spontaneous improvisation and figural creativity. Cofilin 1-mediated biphasic F-actin dynamics of neuronal cells affect herpes simplex virus 1 infection and replication. A modular program for prediction of scalar couplings and fast implementation of Karplus relationships. The differential expression of hundreds of tightly, transcriptionally controlled genes in isolated human colorectal cancer and respective normal mucosa from two patients was analyzed by the cDNA macroarray technique. The second is a ferrocolloid with heterogeneous chainlike aggregates. The volumes of the cerebellar hemispheres (excluding the vermis and the peduncles), the vermis, and the ventral pons were estimated from the prospectively acquired MR scans of 190 healthy volunteers (aged 18-81 years). In this review, current knowledge about the principal microbiological activities and biochemical modifications which occur during the processing of the alkaline condiments including nutritional, antimicrobial, and probiotic aspects are discussed.

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The biochemical data on binding of 3H-QNB in connection with the marked electrophysiological changes induced by QNB suggest a substantial contribution of muscarinic cholinergic transmission in the cat retina. Observation of fiber fuse propagation speed with high temporal resolution using heterodyne detection and time-frequency analysis. The incidence of stroke in elderly patients is 5 times higher than in patients in sinus rhythm. The paper presents an example of constructing and testing an experimental model which may assess different manifestations of CNS functions. Using the aversively motivated 14-unit T-maze (Stone maze) the bystolic dosage levels injection of raclopride, a D(2) receptor antagonist, into the ventral hippocampus (8 microg/kg) was found to impair memory performance. Strenuous exercise in an untrained woman might augment prothrombotic hemostasis profile. Molecular characterization of a phage-inducible middle promoter and its transcriptional activator from the lactococcal bacteriophage phi31. A 24-week, randomised, triple-blind, placebo controlled trial on the symptomatic effectiveness of doxycycline twice a day 100 mg in knee osteoarthritis patients according to the clinical and radiological American College of Rheumatology classification criteria. Chest imaging shows the presence of multiple, bilateral small nodules and diagnosis usually requires a lung biopsy.

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Single nucleotide polymorphism of rs430397 in the fifth intron of GRP78 gene and clinical relevance of primary hepatocellular carcinoma in Han Chinese: risk and prognosis. Published data on thyroid diseases on women xanax drug classification texas in the reproductive age group over the last four decades were utilised. A finely tuned balance between chondrocyte-derived signals repressing cartilage maturation and endothelial signals promoting late differentiation of chondrocytes is essential for normal endochondral ossification during development, growth, and repair of bone. Baseline values for the observe subscale of the FFMQ were unexpectedly high. The pattern and magnitude of the strains, however, were closer to those in the intact femur after insertion of the experimental stem than in the reference stem. We present new findings indicating that the cis-9,trans-11 CLA isomer enhances growth and probably feed efficiency in young rodents.

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Rosiglitazone at the concentrations used in the present experiment is able to inhibit Ang II-induced CRP generation in HAECs by regulating AT(1)-ROS-MAPK signal pathway. To study nonhomologous end joining in extracts of two lymphoblastoid cell lines derived from patients with late radionecrosis after radiotherapy. The LDH precursor was synthesized from a cheap deep eutectic solvent (DES) system. Effect of different doses of Manuka honey in experimentally induced mouse typhoid. These data demonstrate a strong relationship between age and prolapse grade, supporting the view of internal rectal albenza annual cost prolapse as a precursor to external prolapse in the spectrum of rectal prolapse disease. Little is known about whether maternal-fetal medicine subspecialists (MFMs) perform terminations for these women. Limited clinical evidence supports the use of immune globulins in the treatment of pertussis and severe streptococcal infection.

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