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Amitrix (Amitriptyline)

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Amitrix is sometimes used off-label, meaning not FDA approved, for certain conditions. Some providers will use this medication to treat nerve pain. This can be helpful for people who have diabetes or fibromyalgia and haven't felt relief with other medications.

Other names for this medication:
Amiclozor, Amicon, Amiline, Amitin, Amitop, Amitrip, Amitrix, Amitwix, Amiwel, Amixide, Amrea, Amsha, Amtran, Amypres, Anitryp, Arpidox, Axtrip, Bluneel, Emotrip, Endep, Eptanol, Estiline, Goldep, Latilin, Latiln, Libral, Limbitrol, Limbival, Normaline, Raitrip, Relidep, Ristryl, Ronet, Tablin, Tadamit, Tridep, Triplent, Tryline, Tryptomec, Typteez, Vanatrip

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Also known as: Amitriptyline


Amitrix (amitriptyline) is a tricyclic antidepressant with sedative effects. Amitriptyline affects certain chemical messengers (neurotransmitters) that communicate between brain cells and help regulate mood.

Amitrix is a prescription medicine used to treat symptoms of depression.


Usual Adult Dose for Depression:

OUTPATIENTS: -Initial dose: 75 mg orally per day in divided doses; this may be increased to 150 mg/day (if needed) -Maintenance dose: 40 to 100 mg orally per day -Maximum dose: 150 mg/day Alternate outpatient treatment regimen: 50 to 100 mg orally as a single dose at bedtime; this may be increased by 25 or 50 mg as needed at bedtime to a total of 150 mg/day INPATIENTS: -Initial dose: 100 mg orally per day -Maintenance dose: 40 to 100 mg orally as a single dose at bedtime -Maximum dose: 300 mg/day Comments: -Dose increases should preferably be made in the late afternoon or at bedtime due to the sedative effect. -The full therapeutic effect may take as long as 30 days to develop. -Maintenance doses should be reduced to the lowest amount that will maintain relief of symptoms when satisfactory improvement has been obtained. -Maintenance therapy should be continued for 3 months or longer to lessen the possibility of relapse. Use: Relief of symptoms of depression

Usual Geriatric Dose for Depression:

10 mg orally 3 times a day AND 20 mg orally once a day at bedtime Comments: -The full therapeutic effect may take as long as 30 days to develop. -Elderly patients should be monitored carefully and serum levels obtained as clinically appropriate. -Dose adjustments should be made according to clinical response. Use: Relief of symptoms of depression

Usual Pediatric Dose for Depression:

12 years or older: 10 mg orally 3 times a day AND 20 mg orally once a day at bedtime Comments: -The full therapeutic effect may take as long as 30 days to develop. -Dose adjustments should be made according to clinical response. Use: Relief of symptoms of depression

Detailed Amitrix dosage information


If you overdose Amitrix and you don't feel good you should visit your doctor or health care provider immediately. Symptoms of Amitrix overdosage: seizures, loss of consciousness for a period of time, seeing things or hearing voices that do not exist, agitation, feeling drowsy, rigid muscles, vomiting, high temperature, cold body temperature, problems concentrating, abnormal heartbeats, confusion.


Store at room temperature between 20 and 25 degrees C (68 and 77 degrees F) away from moisture and heat. Throw away any unused medicine after the expiration date. Keep out of the reach of children.

Side effects

The most common side effects associated with Amitrix are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.


Do not take Amitrix if you are allergic to Amitrix components. Do not take Amitrix if you are pregnant, planning to become pregnant, or are breast-feeding. Be careful with Amitrix if you suffer from or have a history of a history of heart attack, stroke, bipolar disorder (manic-depression), schizophrenia or other mental illness, diabetes, overactive thyroid, glaucoma, problems with urination, heart disease, seizures. Be careful with Amitrix if you are taking guanethidine (Ismelin), disulfiram (Antabuse), heart rhythm medications such as flecainide (Tambocor), propafenone (Rhythmol), quinidine (Cardioquin, Quinidex, Quinaglute), cimetidine (Tagamet). Avoid alcohol. Be careful! Taking Amitrix you can become suicidal. Be careful when you are driving or operating machinery. Be careful with Amitrix if you are going to have a surgery. It can be dangerous to stop Amitrix taking suddenly.

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Participants concurred that improving the environment for patients concurrently improves the environment for learners. Inhibition of tumour growth by dBP4 was accompanied by the increased endothelial cell apoptosis. 1,2,5-Thiadiazole analogues of aceclidine as potent m1 muscarinic agonists. A Curtin-Hammett mechanism for the copolymerization of ethylene and methyl acrylate monomer using a PymNox nickel catalyst as revealed by DFT computational studies. With combined exposure, the cadmium content of the lungs increased permanently relative to that of the lungs of just cadmium-treated animals.

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Based on recent published data, we illustrate the picture of stem cells with emphasis on their open chromatin conformation. The main objective of this study was to refine more precisely the gene expression patterns used to distinguish serous from endometrioid endometrial carcinoma. Orexin-A significantly stimulated CRF and NPY release from hypothalamic explants in vitro. The exochorion and endochorion are electron-dense and homogeneous in structure. However, repression of PI3K-AKT activation by NCKU-21 was found in CL1-5 cells but not in A549 cells. Effects of lysozyme dimer on humoral response to sheep erythrocytes in non-treated and cyclophosphamide cipro breastfeeding category -immunosuppressed mice. Construction and biological characteristic for the recombinant modified vaccinia virus ankara co-expressing modified GP5 and M protein of porcine reproductive and respiratory syndrome virus. Risk analysis of the effect of pramlintide treatment demonstrated risk-reduction effects independent of changes in average glycemia, most notably reduced rate and magnitude of postprandial BG fluctuations. PBRM1 was found to be downregulated in primary tissues from patients with CRC or IBD, and its expression correlated negatively with that of RLR genes and ISGs (interferon-stimulating genes) in CRC samples. Systemic antibiotic therapy appears to be beneficial in resolving certain periodontal infections and associated disease.

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