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Alprocalm (Alprazolam)

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Alprocalm is a potent, short-acting benzodiazepine anxiolytic—a minor tranquilizer. It is commonly used for the treatment of anxiety disorders, especially of panic disorder. It's also used in the treatment of generalized anxiety disorder (GAD) or social anxiety disorder. It was the 12th most prescribed medicine in the United States in 2010. Alprocalm, like other benzodiazepines, binds to specific sites on the GABAA receptor. It possesses anxiolytic, sedative, hypnotic, skeletal muscle relaxant, anticonvulsant, amnestic, and antidepressant properties. Alprocalm is available for oral administration as compressed tablets (CT) and extended-release capsules (XR).

Other names for this medication:
Acalm, Almee, Alpraday, Alpramax, Alpranex, Alprocontin, Alprogard, Alpronit, Alzocum, Alzolite, Anxitab, Anxorel, Anxyl, Axnil, Azicalm, Calmtec, Depoxit, Finezol, Indolam, Kurelam, Mcalm, Mebrin, Nokzok, Pacyl, Pizolam, Samprex, Synozolam, Tenrid, Tensyn, Trustin, Unixl, Visram

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Lopid, Precose, Dramamine, Neurontin, Phenergan, Addyi, Zanaflex, Rulide, Avapro, Fursemid, Moximat, Fenofibratum, Glybovin, Zidolam, Zimox, Storvas, Amoksicilin, Ulticadex, Normaxin,

Also known as: Alprazolam


Alprocalm is a benzodiazepine (ben-zoe-dye-AZE-eh-peen). Alprazolam affects chemicals in the brain that may be unbalanced in people with anxiety. Alprocalm is used to treat anxiety disorders, panic disorders, and anxiety caused by depression.

You should not use Alprocalm if you have narrow-angle glaucoma, if you also take itraconazole or ketoconazole, or if you are allergic to Alprocalm or similar medicines (Valium, Ativan, Tranxene, and others).

Alprazolam may be habit-forming. Misuse of habit-forming medicine can cause addiction, overdose, or death.

Do not drink alcohol while taking Alprocalm. This medication can increase the effects of alcohol. Alprazolam may be habit-forming and should be used only by the person for whom it was prescribed. Keep the medication in a secure place where others cannot get to it.


Take Alprocalm exactly as prescribed by your doctor. Follow all directions on your prescription label. Never use Alprocalm in larger amounts, or for longer than prescribed. Tell your doctor if the medicine seems to stop working as well in treating your symptoms.

Alprocalm may be habit-forming. Never share Alprocalm with another person, especially someone with a history of drug abuse or addiction. Keep the medication in a place where others cannot get to it.

Misuse of habit-forming medicine can cause addiction, overdose, or death. Selling or giving away this medicine is against the law.

Do not crush, chew, or break a Alprocalm extended-release tablet. Swallow the tablet whole. Call your doctor if this medicine seems to stop working as well in treating your panic or anxiety symptoms. Do not stop using Alprocalm suddenly, or you could have unpleasant withdrawal symptoms. Ask your doctor how to safely stop using this medicine.


Seek emergency medical attention or call the Poison Help line at 1-800-222-1222. An overdose of alprazolam can be fatal.

Overdose symptoms may include extreme drowsiness, confusion, muscle weakness, loss of balance or coordination, feeling light-headed, and fainting.


Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing.

Keep out of the reach of children.

Do not keep outdated medicine or medicine no longer needed.

Ask your healthcare professional how you should dispose of any medicine you do not use.

It is very important to protect the orally disintegrating tablets from moisture. Remove and throw away any cotton packaging from the medicine bottle when you first use the medicine.

Detailed Alprocalm XR dosage information

Side effects

The most common side effects associated with Alprocalm are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.


Appropriate studies have not been performed on the relationship of age to the effects of alprazolam in the pediatric population. Safety and efficacy have not been established.

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Tunneled Pleural Catheter Placement with and without Talc Poudrage for Treatment of Pleural Effusions Due to Congestive Heart Failure. In particular, the serine is not flanked by arginine, previously thought to be an essential adjunct for a serine residue to act as substrate for this kinase. Incorporation was sensitive to chloramphenicol or RNase but resistant to cycloheximide, required magnesium, and was stimulated by nucleotides. To investigate the causes of refractory pharyngeal paraesthesia. Radiographic studies in toxicology may confirm a diagnosis and assist in therapeutic intervention. Allorecognition of HLA-B5 cross reactive group antigens by human CTL clones. Studies on the action mechanism in electric double stimulation of the heart.

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Myo2, a class-II myosin, is the major source of tension in the contractile ring, but how Myo2 is anchored and regulated to produce force is poorly understood. Dehydrated Allogenic Human Amniotic Membrane Graft for Conjunctival Surface Reconstruction Following Removal of Exposed Scleral Buckle. By the end of the 4-week measurement period, the beans and barley were almost mature. Evaluation of hypertension and related target organ damage by average day-time blood pressure. There is the suggestion of more doctor dominance and a less patient-centred approach when comparisons are made with previous work on face-to-face consultations. In comparable muscles, regenerated LPN-blocked motor units produced only about half the tension of the controls. Results provide a clear picture of nursing activity in general intensive care units, allows to tailor the Nursing Intervetions Classification in Catalonia context and to confirm findings of previous studies. The muropeptide of the transconjugant contained a significantly greater amount of tetrapeptides than the muropeptide of strain SK110, which could have decreased the susceptibility of the cells to lysis and thereby the release of intracellular debittering enzymes. Unintentionally, a significant subgroup of adolescents may develop problems that are a result of alcohol misuse. These interregional genetic exchanges provided ample opportunity for the re-use of standing genetic variation, which could facilitate mangrove establishment and adaptation in new habitats, especially in the context of global climate changes.

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Irrigation and minimal debridement in the outpatient setting is an acceptable method of treatment for low energy gunshot wounds to the lower limbs, without orthopaedic or vascular involvement. Modifications of the glucose-6-phosphate dehydrogenase activity in the granular leukocytes of guinea pigs poisoned by typhoid endotoxin. We found distinct activity patterns and stimulation effects of two major interneuron subtypes, parvalbumin (PV)- and somatostatin (SOM)-expressing interneurons, in the medial prefrontal cortex of mice performing a spatial working memory task. were completely cured by daily injections of ascites containing IC5F5. This report describes a rare case of long-standing mandibular dislocation and its treatment by condylectomy, coronoidectomy, and suprahyoid myotomy. Disruption of SGP2 confers temperature-sensitive growth and a-specific sterile phenotypes, characteristics similar to those conferred by the dpr1 (ram) mutation, a suppressor of RAS2Val-19. australis were the most divergent species when compared to the other species examined.

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bisporus was investigated with real-time PCR revealing influence of the carbon source on pdh expression levels. Benefit of adjuvant imatinib therapy following curative resection in patients with intermediate-risk gastrointestinal stromal tumor (GIST) is unclear. Asymptomatic Chilean elderly with poor vitamin B-12 status displayed improved conductivity in myelinated peripheral nerves after vitamin B-12 treatment and an interaction with folate status, which was detected only with the use of cB-12. The results of this study may help guide and improve contraceptive counseling services for breast cancer survivors. A cloned fragment of Salmonella typhimurium DNA complemented the defect in cobalamin uptake of Escherichia coli or S. These data suggest that Jab1 is an important upstream negative regulator of p57 and that aberrant expression of Jab1 in HCC could lead to a significant decrease in p57 levels and contribute to tumor cell growth.

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Using a split luciferase assay, a bioluminescence resonance energy transfer technique, and site-directed mutagenesis, we examined the domains involved in HuR multimerization. This study suggests that repeated CTN applications could lead to the accumulation of CTN residue and generate somewhat inconsistent and erratic effects on the abundances of key functional genes related to soil N cycling. The use of immunotoxins (ITs) to eliminate HIV-infected cells is discussed. Camptocormia: pathogenesis, classification, and response to therapy. Portal vein pulsatility ratio provides a measure of right heart function in chronic heart failure. COGNITIVE ABNORMALITIES IN POSTOPERATIVE PERIOD OF THYROID SURGERY.

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Plasmodium berghei infections in gnotobiotic mice and rats: parasitologic, immunologic and histopathologic observations. The purpose of this study was to assess the 12-month outcomes associated with naturalistic antipsychotic treatment of patients participating in the Schizophrenia Outpatient Health Outcomes (SOHO) study. 2D and 3D Cu(hfac)2 complexes with nitronyl nitroxide biradicals. A BLUEPRINT for improving NHS care has been announced by the Scottish government. The performance of the SVM classifier is evaluated for two different databases. The project not only provides an example of the efficient exchange and use of hospital-based data for teaching purposes but also provides the groundwork for many potential and exciting developments in national and international nursing data exchange.

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Understanding and responding to racial differences in drug court outcomes. Attention-Deficit/Hyperactivity Disorder (ADHD) and Obesity: Update 2016. Total synthesis and expression of a gene for the alpha-subunit of bovine rod outer segment guanine nucleotide-binding protein (transducin). Discussed also are the concerns for patient addiction and the WHO Cancer Pain Relief program. One of the regulatory targets of bldH is an extracellular protease inhibitor protein that is likely to delay the digestion of the primary biomass until the colony is ready for aerial growth. In addition, we evaluated the influence of static and perfusion culture on NSCs. Transducin activation by rhodopsin without a covalent bond to the 11-cis-retinal chromophore. The response of Dunning R3327 prostatic adenocarcinoma to IL-2, histamine and radiation. Aldioxa improves delayed gastric emptying and impaired gastric compliance, pathophysiologic mechanisms of functional dyspepsia. Cell hypertrophy and type X collagen synthesis in cultured articular chondrocytes.

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Melatonin (MT), a naturally occurring pituitary hormone has a sleep promoting effect. Growth in Vitro of Marigold and Tobacco Tissue with Nucleic Acids and Related Compounds. The use of intravenous (IV) PEN for PJP prophylaxis has been evaluated in pediatric patients. Models that explicitly include interactions among these four factors explained over half of the variance in annual growth for four out of five species using annual climate. Although the encounter process has a stochastic element, the observed value of the lunar inclination is among the most likely outcomes for a wide range of parameters. To evaluate characteristics of TB patients that are predictive of tuberculous infection in their close contacts. Glycolipids of mouse erythroleukemia cells (Friend cells) and their alteration during differentiation.

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The expectation is that returning to active sports after cervical TDR is not restricted. Combined high-resolution magnetic resonance imaging and histological examination to explore the role of ligaments and tendons in the phenotypic expression of early hand osteoarthritis. However, most of the studies carried out using in vitro models do not continue with further studies in estrogen-receptor-positive singulair generic in vivo breast cancer models, or fail to examine the possible biochemical mechanisms of phytochemical-based amelioration. mRNA regulation and ribonomics occur in brain ischemia and reperfusion (I/R) following stroke and cardiac arrest and resuscitation. In both cases, the ARMS subtype was confirmed using FOXO1 break-apart probes (FISH). Nephrotic syndrome is associated with abnormal regulation of renal water excretion. Pure laparoscopic living donor hepatectomy: Focus on 55 donors undergoing right hepatectomy.

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Processes for the administration of tests to large groups are explained, and advantages and disadvantages are explored. Sulfhydryls associated with H2O2-induced channel activation are on luminal side of ryanodine receptors. Clients aiming to abstain from drinking were more likely to be in retreatment, to be assigned to treatment by a health institution, to have no at-risk alcohol use, and to be already alcohol abstinent at the time of admission relative to clients who aimed to control their drinking. The correlation between measurements and slit-lamp ratings was 0.78 for flare and 0.56 for cells. Tissues were collected from fetuses at 90 and 110 d of gestation and from pigs at 1, 21, 90 and 180 d of age. It will allow the industry to enhance its corporate citizenship whilst improving its competitive advantage for long-term. Comparative study of the occurrence of enterobacteria, Escherichia coli, coliforms, colony count, fecal streptococci and Pseudomonas aeruginosa. PD effluent CA125 concentrations were associated with peritoneal protein losses and increased by the usage of higher glucose dialysates to compensate for loss of residual renal function. During this, the duration of freezing, rearings, bouts of micturition and number of fecal boli were recorded.

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Furthermore, to determine whether Cat K processing and maturation signaling involves protein kinase C (PKC), mouse total bone cells were treated with calphostin C, a specific inhibitor of PKC, however, no effect was observed, indicating that PKC calphostin C did not affect to osteoclast-mediated Cat K processing and maturation in osteoclast. Microbiological and chemical characteristics of white bread during storage in paper-packages modified with Ag/TiO2-SiO2, Ag/N-TiO2 or Au/TiO2 were investigated. It is secured to the analog, and its design is customized by machining the abutment to suit the particular clinical circumstances. Further research is needed to determine the cause of the decrease in inhalant abuse. Task-related increases in fatigue predict recovery time after academic stress. Anomalies of pulmonary veins: usefulness of spin-echo and gradient-echo MR images.

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In wild-type, but not Atm-/- mice, up-regulation suprax uti dosing of p53 coincided with cell death, suggesting that Atm-dependent apoptosis in the CNS is mediated by p53. Levels of interferon alpha and gamma in seminal plasma of normozoospermic, oligozoospermic,and azoospermic men. The third, a potential control of the endosymbiont DNA replication and repair systems through the transfer of nuclear-encoded proteins, could explain the lower rates in long-term obligate endosymbionts. The numerical, as well as the optical reconstructed images with the proposed method are of higher visual quality and contain less speckle noise compared to the original random phase method, which add the random phase to the target image and then preserve the phase component of the complex hologram. No phosphite-oxidizing activity could be detected in whole cells or cell-free extracts of phosphate-grown cells. The role of the renin angiotensin aldosterone system (RAAS) and the gene variants of its components in susceptibility to diabetic nephropathy (DN) have been investigated in numerous studies. Previous studies revealed novel genetic changes in the duodenal mucosa of iron-deprived rats during postnatal development. Wrist arthroscopy has evolved to be an essential diagnostic and therapeutic tool in the armamentarium of every surgeon treating disorders of the wrist. Epidemiological study on intestinal and urinary schistosomiasis in the area of the Lufira artificial lake (Katanga).

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Histologically, the tumor had components of both well-differentiated tubular adenocarcinoma and neuroendocrine carcinoma, which is classified as MANECs according to the 2010 WHO classification of endocrine tumors. Factors influencing the course of reaction of staphylococcal lysozyme. To promote consumption of FVs better, nutrition education programs such as Extension should differentiate based on stages of change among subpopulations. Each slave-maker species alone had a negative impact on its hosts, although one slave-maker species more frequently decimated its host assemblage and then went extinct. Tetramethylpyrazine alleviates neural apoptosis in injured spinal cord via the downregulation of miR-214-3p. Four subgroups of patients with different constellations of social support and knowledge of the disease were identified in cluster analysis and were demonstrated to differ significantly on four disease-related appraisals: Profit, Challenge, Harm, and Value. Native State Volume Fluctuations in Proteins as a Mechanism for Dynamic Allostery. The Effects of an Orientation Program on Quality of Life of Patients with Thalassemia: a Quasi-Experimental Study.

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To observe the changes in substance P in myocardium and dorsal root ganglion (DRG) following ligation of the left anterior descending branch of coronary artery. Abstracts for the 18th annual meeting of the European Society for Dermatologic Research. The inter-observer and intra-observer agreement of CCT measurement by OCT were analyzed by interclass correlation coefficient (ICC). Compared to the values on admission, the patients showed significantly increased platelet aggregability (p less than 0.05) and thromboxane release (p less than 0.001) 1 to 2 weeks after SAH. Moreover, ten more flasks and better distribution were needed for adherent culture to acquire an equal amount of SFAE in comparison with suspension culture. BMI, body mass indexCSM, cervical spondylotic myelopathymJOA, modified Japanese Orthopaedic AssociationOPLL, ossification of the posterior longitudinal ligament. The second mesiobuccal canal was present in almost two thirds of first and less than half of second molars.

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We evaluated the role of sulfidopeptide leukotrienes as mediators of endotoxin-induced respiratory failure in pigs. Interrogating the interplay between nuclease-helicase Dna2 and Holliday junction (HJ) resolvase Yen1, we find the Dna2 helicase activity acts parallel to homologous recombination (HR) in promoting DNA replication and chromosome detachment at mitosis after replication fork stalling. The significance of recurrent nerve paresis for the operability of lung cancer. Specifically, the ability for ATP binding/hydrolysis has little consequence for the MMR-dependent damage response. However, results presented here indicate the most, if not all of the activity present within the lymphoid tissues of RCS-bearing mice is mediated by RCS-activated, host NK cells.

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