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Alpostin (Alprostadil)
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Alpostin

Alpostin injection is used to treat men who have erectile dysfunction (also called sexual impotence). It belongs to a group of medicines called vasodilators that can increase blood flow by expanding blood vessels. This medicine causes an erection because it increases the blood flow to the penis.

Other names for this medication:
Alpostin, Caverject, Edex, Muse, Prostin, Vitaros

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Also known as: Alprostadil

Description

This medication is used to treat male sexual function problems (erectile dysfunction). It works by helping the blood flow into the penis to achieve and maintain an erection. This medication is not for use in women or children.

Dosage

A healthcare provider will give your first dose and teach you how to properly use the medication by yourself.

Follow all directions on your prescription label and read all medication guides. Use the medicine exactly as directed.

Alpostin is used only when needed. An erection should occur within 5 to 20 minutes and last up to 60 minutes.

Alpostin injection is injected into the side of the penis.

Alprostatil transurethral pellet is a very small suppository to be inserted into the opening of the penis (the urethra).

Do not use more than 2 pellets in one day. Do not use more than 3 injections per week. Wait at least 24 hours between each injection.

Ask your doctor or pharmacist if you don't understand how to use the injection.

Prepare an injection only when you are ready to give it. Call your pharmacist if the medicine looks cloudy, has changed colors, or has particles in it.

Do not reuse a needle or syringe. Place them in a puncture-proof "sharps" container and dispose of it following state or local laws. Keep out of the reach of children and pets.

Call your doctor if a needle breaks while you are injecting Alpostin. If you can grasp the broken end, remove the needle right away.

Your doctor should check you every 3 months to be sure Alpostin is not causing harmful effects on your penis.

Storing Alpostin:

Keep pellets in their original foil pouch in the refrigerator. You may store a pouch at cool room temperature for up to 14 days. Protect from freezing or extreme heat. Do not store in a closed automobile or in luggage while traveling. Store Alpostin injection vials at cool room temperature. The 40-microgram strength should be used within 3 months or before the expiration date on the label. After mixing a Caverject injection, keep it at room temperature and use within 24 hours.

Detailed Alpostin dosage information

Overdose

If overdose is suspected, contact a poison control center or emergency room immediately. US residents can call their local poison control center at 1-800-222-1222. Canada residents can call a provincial poison control center. Symptoms of overdose may include: fainting, painful/prolonged erection.

Storage

Keep out of the reach of children.

Do not keep outdated medicine or medicine no longer needed.

Ask your healthcare professional how you should dispose of any medicine you do not use.

Store in the refrigerator. Do not freeze.

Alpostin for Injection while in the powder form can be stored at room temperature (between 15 and 25 °C or 59 and 77 °F) for 3 months. After it is mixed, the solution must be used immediately or within 24 hours and not refrigerated or frozen. Suppositories may be stored at room temperature.

Side effects

The most common side effects associated with Alpostin are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.

Contraindications

Alpostin injection is not indicated for use in newborns and should not be used in children.

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This is the first demonstration that EZH2 expression can be upregulated in fresh lymphoma cells. In the Corrona registry, the HZ risk in RA patients taking prior or current MTX increased with older age and higher prednisone dose. Classic theories of object-based attention assume a single object of selection but real-world tasks, such as driving a car, often require attending to multiple objects simultaneously. There is limited evidence for the effectiveness of person-directed interventions aimed at reducing stress levels in healthcare workers. Leukaemic cells from six CML patients from whom samples could be obtained during chronic phase and at the time of blast crisis (BC) were compared for sensitivity to STI571, using an in vitro assay. Both the large-exit-time and the small-exit-time tails of the distribution are suppressed exponentially, and the corresponding decay coefficients are in excellent agreement with theoretical values. Fullbred Chinese and Indian rhesus macaques represent genetically distinct populations. Specific P450 inhibitors (sulfaphenazole, quinidine sulfate, coumarin, diethyldithiocarbamic acid, troleandomycin, and furafylline) and specific cDNA-expressed P450s were used to identify the major isoforms responsible for the oxidation of SPZS to SPZ and SPZ to SPZO.

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We prospectively studied previously healthy children aged less than 2 years admitted for RSV infection during an epidemic season. First, competing language and nonlanguage tasks appear to share limited-capacity, parallel albenza dose children processing resources. Cost per life year gained at five years and lifetime treatment with ramipril. The subjects were 131 male and 123 female patients with a mean age of 42.7 years (SD 25.9) median age of 42 years and an age range of 1-95 years. Since we have previously shown (Jumarie and Malo, 1994, in Vitro Cell. Water-soluble chitosan macromolecules self-aggregate into amorphous sheets on solidification, presenting an interesting way to inspire new structures of chitosan assemblies.

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