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Alpertan (Valsartan)

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Alpertan works by blocking the action of certain natural substances that tighten the blood vessels, allowing the blood to flow more smoothly and the heart to pump more efficiently. Alpertan is in a class of medications called angiotensin II receptor antagonists.

Other names for this medication:
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Also known as: Valsartan


Alpertan (valsartan) is an angiotensin II receptor blocker (sometimes called an ARB). Valsartan keeps blood vessels from narrowing, which lowers blood pressure and improves blood flow.

Alpertan is used to treat high blood pressure (hypertension) in adults and children who are at least 1 year old. Lowering blood pressure may lower your risk of a stroke or heart attack.

Alpertan is also used in adults to treat heart failure and lower your risk of needing to be hospitalized, and to lower your risk of death after a heart attack.


To treat high blood pressure: 80 mg or 160 mg or more once a day. The maximum dosage is 320 mg a day. To treat heart failure: 40 mg twice a day. The maximum dosage is 320 mg daily. Take Alpertan tablets orally with or without food. Do not crush or chew it. Take Alpertan at the same time every day with water. If you want to achieve most effective results do not stop taking Alpertan suddenly.


Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.

Overdose symptoms may include fast heartbeats or fainting.


Store at room temperature between 15 and 30 degrees C (59 and 86 degrees F) away from moisture and heat. Keep your medicine container tightly closed. Throw away any unused medicine after the expiration date. Keep out of the reach of children.

Side effects

The most common side effects associated with Alpertan are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.


You should not use this medicine if you are allergic to valsartan or hydrochlorothiazide, or if you have:

decreased urination or are unable to urinate; or an allergy to sulfa drugs.

If you have diabetes, do not use Alpertan HCT together with any medication that contains aliskiren (a blood pressure medicine).

You may also need to avoid taking Alpertan HCT with aliskiren if you have kidney disease.

Tell your doctor if you have ever had:

an electrolyte imbalance (such as low levels of potassium or magnesium, or high levels of calcium in your blood); liver disease; kidney disease; gallstones; lupus; congestive heart failure; gout, or high levels of uric acid in your blood; asthma or allergies; high cholesterol or triglyceride levels; an allergy to penicillin; glaucoma; or if you are on a low-salt diet.

Do not use if you are pregnant. Stop using the medicine and tell your doctor right away if you become pregnant. Valsartan can cause injury or death to the unborn baby if you take the medicine during your second or third trimester.

You should not breastfeed while using this medicine.

Alpertan HCT is not approved for use by anyone younger than 18 years old.

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