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Alpam (Alprazolam)
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Alpam

Alpam is used to treat anxiety and panic disorders. It belongs to a class of medications called benzodiazepines which act on the brain and nerves (central nervous system) to produce a calming effect. It works by enhancing the effects of a certain natural chemical in the body (GABA). Alpam is mostly used to treat anxiety disorders, panic disorders, and nausea due to chemotherapy. Alpam may also be indicated for the treatment of generalized anxiety disorder, as well as for the treatment of anxiety conditions with co-morbid depression. The FDA label advises that the physician should periodically reassess the usefulness of the drug.

Other names for this medication:
Aderta, Aleez, Alflux, Alprac, Alpracon, Alpramax, Alpron, Alwe, Alzoax, Ambulax, Ambutech, Ateez, Benzax, Betapax, Calmtec, Coolam, Depser, Depsolam, Dexolam, Maxorest, Mebrin, Meloprax, Parazolam, Plxna, Poize, Prazil, Prolam, Propnix, Proprazolam, Prozam, Prozolam, Rescalm, Restyl, Samprex, Sanprazole, Sowel, Suzilam, Tagat, Tenil, Tensfree, Tryzo, Unixl, Zedep, Zeecam, Zeprax, Zocam, Zolax, Zoloid, Zopax, Zorest

Similar Products:
Cozaar, Astelin, Omnicef, Lamictal, Clozaril, Floxin, Revia, Xenical, Epivir, Noroxin, Bactrizol, Metoclop, Tenan, Wingyl, Clarogen, Biclar, Intramet, Albonzol,

Also known as: Alprazolam

Description

Alpam (alprazolam) is a benzodiazepine (ben-zoe-dye-AZE-eh-peen). It is thought that alprazolam works by enhancing the activity of certain neurotransmitters in the brain.

Alpam is used to treat anxiety disorders and anxiety caused by depression.

Alpam is also used to treat panic disorders with or without a fear of places and situations that might cause panic, helplessness, or embarrassment (agoraphobia).

It is dangerous to purchase Alpam on the Internet or outside the United States. The sale and distribution of medicines outside the U.S. does not comply with safe-use regulations of the Food and Drug Administration (FDA). These medications may contain dangerous ingredients, or may not be distributed by a licensed pharmacy.

Dosage

Take Alpam XR exactly as it was prescribed for you. Do not take the medication in larger amounts, or take it for longer than recommended by your doctor. Follow the directions on your prescription label.

Your doctor may occasionally change your dose to make sure you get the best results from this medication.

Alpam XR may be habit-forming and should be used only by the person it was prescribed for. Alpam XR should never be shared with another person, especially someone who has a history of drug abuse or addiction. Keep the medication in a secure place where others cannot get to it. Do not crush, chew, or break a Alpam extended-release tablet. Swallow the tablet whole. It is specially made to release alprazolam slowly in the body. Breaking the tablet would cause too much alprazolam to be released at one time.

Contact your doctor if this medicine seems to stop working as well in treating your panic or anxiety symptoms.

Your symptoms may return when you stop using Alpam XR after using it over a long period of time. You may also have seizures or withdrawal symptoms when you stop using Alpam XR.

Withdrawal symptoms may include blurred vision, trouble concentrating, loss of appetite, diarrhea, muscle twitching, numbness or tingling, or increased sensations.

Do not stop using Alpam XR suddenly without first talking to your doctor. You may need to use less and less before you stop the medication completely.

To be sure this medication is helping your condition, your doctor will need to check your progress on a regular basis. Do not miss any scheduled visits to your doctor.

Store Alpam XR at room temperature away from moisture, heat, and light. Remove any cotton from the bottle of disintegrating tablets, and keep the bottle tightly closed.

Keep track of how many pills have been used from each new bottle of this medicine. Benzodiazepines are drugs of abuse and you should be aware if any person in the household is using this medicine improperly or without a prescription.

Detailed Alpam XR dosage information

Overdose

Seek emergency medical attention or call the Poison Help line at 1-800-222-1222. An overdose of alprazolam can be fatal.

Overdose symptoms may include extreme drowsiness, confusion, muscle weakness, loss of balance or coordination, feeling light-headed, and fainting.

Storage

Store at room temperature away from light and moisture. Do not store in the bathroom. Keep all medications away from children and pets.Do not flush medications down the toilet or pour them into a drain unless instructed to do so. Properly discard this product when it is expired or no longer needed. Consult your pharmacist or local waste disposal company for more details.

Side effects

The most common side effects associated with Alpam are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.

Contraindications

Drug interactions may change how your medications work or increase your risk for serious side effects. This document does not contain all possible drug interactions. Keep a list of all the products you use (including prescription/nonprescription drugs and herbal products) and share it with your doctor and pharmacist. Do not start, stop, or change the dosage of any medicines without your doctor's approval.Some products that may interact with this drug include: kava, sodium oxybate.Other medications can affect the removal of Alpam from your body, which may affect how Alpam works. Examples include azole antifungals (such as itraconazole, ketoconazole), cimetidine, certain anti-depressants (such as fluoxetine, fluvoxamine, nefazodone), drugs to treat HIV (delavirdine, protease inhibitors such as indinavir), macrolide antibiotics (such as erythromycin), rifamycins (such as rifabutin), St. John's wort, drugs used to treat seizures (such as carbamazepine, phenytoin), among others.Tell your doctor or pharmacist if you also take drugs that cause drowsiness such as: certain antihistamines (such as diphenhydramine), medicine for sleep or anxiety (such as diazepam, zolpidem), muscle relaxants, narcotic pain relievers (such as codeine), psychiatric medicines (such as chlorpromazine, risperidone, amitriptyline, trazodone).Check the labels on all your medicines (such as cough-and-cold products) because they may contain ingredients which cause drowsiness. Ask your pharmacist about the safe use of those products.Cigarette smoking decreases blood levels of this medication. Tell your doctor if you smoke or if you have recently stopped smoking.

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By destabilizing lipid bilayers of mitochondria and lysosomes, BA triggers the misbalance in the mitochondrial-lysosomal axis leading to perceived autophagy impairment, lipofuscinogenesis, genomic instability and cell senescence. The right ophthalmic artery originated from the ipsilateral middle meningeal artery. After transduction with the rAd5F35-MUC1 adenoviral vector, Mo-DC also expressed MUC1 with tumor-associated glycosylation (Tn and T glycoforms), although no changes in mRNA levels of relevant glycosyltransferases could be demonstrated. Effects of methylglyoxal and glyoxalase I inhibition on breast cancer cells proliferation, invasion, and apoptosis through modulation of MAPKs, MMP9, and Bcl-2. It is well established that the comprehension of spoken words referring to object concepts relies on high-level visual areas in the ventral stream that build increasingly abstract representations.

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Besnier-Boeck-Schaumann disease with laterocervical lymph node onset. The mean operating time was 42 minutes (range 31 to 59) for each partial nephrectomy. To compare glucagon-provoked acute insulin responses, as well as changes of gut and pancreatic hormones and adipokines between patients with T2DM after RYGB and SG at one year post-operatively, a total of 14 RYGB and 13 SG patients were followed-up and evaluated for glucose metabolism, gut and pancreatic hormones, and adipokines. Clinical significance of peripheral blood neutrophil-lymphocyte ratio and platelet- lymphocyte ratio in patients with asthma. On Rh immunization and its prevention: observations and thoughts. Cloning, expression and purification of human stem cell growth factor cDNA and its species-specificity in hematopoiesis. Mortality, Geriatric, and Nongeriatric Surgical Risk Factors Among the Eldest Old: A Prospective Observational Study. Inferior and superior vestibular ganglia staining appeared confined to distinct cell regions, varying considerably among cells of different sizes: more intense in small, punctate in some medium and regionally polarized in some large cells.

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This glycoprotein, designated Pltgp40, is an acidic sialylated 40,000-dalton protein that bears both O-linked and N-linked oligosaccharides. Thus, an energy-dependent mechanism is responsible for internalization and may be necessary for any potential interconversion of the higher 170- or 140-kDa proteins to the lower 140- and/or 65-70-kDa binding proteins. In vivo mechanical behaviour of the anterior cruciate ligament: A study of six daily and high impact activities. Adding to the Histone Code at DNA double-strand breaks, Mailand and colleagues now uncover non-degradative ubiquitin marks on linker histone H1 as key signaling intermediates in the DNA damage signal transduction cascade. Study on Platinum Coating Depth in Focused Ion Beam Diamond Cutting Tool Milling and Methods for Removing Platinum Layer. Global spatial autocorrelation was used to describe the entire spatial distribution pattern of the body flea index in the natural plague foci of typical Chinese Mongolian gerbils. Nanoparticle Probes for Structural and Functional Photoacoustic Molecular Tomography. Our findings suggest that HV reduction in individuals at UHR for psychosis is specific to men and linked to reduced post-awakening cortisol concentrations. Isolation and characterization of a cDNA from a human histone H2B gene which is reciprocally expressed in relation to replication-dependent H2B histone genes during HL60 cell differentiation. To explore and summarize the literature reporting the applications of magic tricks or any derived techniques in healthcare or clinical environments.

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Humans and ecosystems are exposed to highly variable and unknown cocktail of chemicals and radiations. These different plasma amino acid profiles and changes in serum biochemistry of cachectic tumor-bearing rats compared with malnourished pair-fed rats suggest specific tumor effects on host metabolism not mediated solely by anorexia. We treated a patient with large multiple chondrosarcomas derived from multiple cartilaginous exostoses. We also show a non-monotonic change in the flow rate of liquid through the constrained microgel, governed by its progressive confinement. It was suggested that strategy training programs should consider the speech intelligibility of the speaker and be tailored according to individual needs. In situ hybridization studies of adult rat sympathetic ganglia using probes specific for the high-affinity neurotrophin receptor transcripts trks A, B, and C demonstrated that neurons in both prevertebral and paravertebral sympathetic ganglia express predominantly trkA receptors in vivo. 30 patients (19 in saffron group and 11 in placebo group) completed the study.

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The right presubiculum volume was correlated with short- and long-delayed recall in right TI patients. Information on formula feeding was collected by questionnaires at 3 months of age. Neuroanatomical and ultrastructural studies of the paired lateral giant nerve fibers (LGFs) in posterior segments of the tubificid worm, Branchiura sowerbyi, demonstrate that the fibers are 1) segmental in origin (two cell bodies per segment), 2) joined longitudinally and transversely to form an intersegmental syncytial network, and 3) surrounded by a myelinlike sheath. Two observations shed light on the question which receptors mediate the above effect in the NRM. The SDML values showed significant sex difference, whereas no sex difference was observed in the amplitude of the EMAPs. In recent years, the analysis of conserved developmental marker genes has assisted the identification of homologies for different parts of the telencephalon among several tetrapod species. Nitro-fatty acids in plant signaling: New key mediators of nitric oxide metabolism. The impact of multiple blood donations on the risk of cardiovascular diseases: Insight of lipid profile. Changes in expression of individual genes (increases or reductions) correlated over time. Quantitative and qualitative assessment of AgNORs in different grades of OSF and to compare the count of AgNORs in different grades of OSF and normal mucosa.

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Chinese law neither generally prohibits nor expressly permits surrogacy. The danger of acute potassium intoxication after late embolectomy. Energy generation is currently a serious concern in the progress of human civilization. Refractory neuropathic inguinodynia following inguinal herniorrhaphy is a common and debilitating complication. Metabolic Pathways for Degradation of Aromatic Hydrocarbons by Bacteria. The literature concerning the temporal evolution of these lesions is meagre and so it is still unclear, whether asymptomatic patients with periprosthetic collections should undergo revision. On the contrary, estradiol totally inhibited the immunosuppressive activity of CyA in any recipients. We advise that homogeneity in codon usage across taxa in a data set be confirmed before codon model-based phylogenetic estimation is attempted. The change of the carrier density in the probe-modified graphene due to the attachment of E.

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To evaluate the visual outcomes and complications of glued foldable intraocular lens (IOL) implantation in patients with a wide range of ocular pathologies and/or having combined surgical procedures. We classified problems of asthma patients into biological, psychological and adherence factors, and investigated factors associated with the indication and failure of a medication step-down treatment. Is a Prehospital Treat and Release Protocol for Opioid Overdose Safe?. The discovery of new natural xanax drug sheet products from fungi isolated from the marine environment has increased dramatically over the last few decades, leading to the identification of over 1000 new metabolites. Interventions to improve care and therapeutic outcomes in this particular population must recognize and attempt to resolve these factors.

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Possible course of subcapsular spleen rupture: the occult spleen rupture syndrome. Liquid chromatography-tandem mass spectrometry data are classified by hierarchical clustering. The intervention in this complex case could successfully be accomplished by performing preplanned virtual transplantations with guided osteotomies to prevent bone loss and ensure accurate donor teeth placement in new recipient sites. As there is no robust theory for initial recombination in liquids to apply, the valid range of general collection efficiencies for the cozaar tablets two-dose-rate method should be experimentally evaluated for each radiation dosimetry application. The resulting Class III malocclusion was treated using maxillary protraction headgear, in conjunction with removable orthodontic appliances and intermaxillary traction. Complement deposition and activation was measured by cell binding and ELISA based assays, and the effect of IVIG on complement deposition was assessed by addition of different concentrations of IVIG. A laboratory study evaluating the pH of various modern root canal filling materials.

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The use of this postembedding immunogold procedure allows equal access of antibodies to all cellular compartments exposed at the section surface, allows quantitative assessment of the immunoreactivity, and affords a high resolution compatible with studies at the organelle level. A subtracted MS-5-cDNA library, which contains cDNA clones corresponding to mRNAs present in MS-5 cells but not in MS-K cells, was constructed. This international study of spinal cord dysfunction showed substantial variation between the different etiologies regarding demographic and clinical characteristics, including changes in AIS between admission and discharge. It has been demonstrated that expression of cyclooxygenase-2 (COX-2) isoform is induced by Entamoeba histolytica in macrophages and polymorphonuclear cells during amoebic liver abscess (ALA) formation in hamsters. In the present study, we used bioinformatic and biochemical analyses to demonstrate that EphA4 is a direct downstream target of miR-335 in human breast cancer MCF-7 and MDA-MB-23 cells and revealed that miR-335 negatively regulates the expression of EphA4 in these cells. Age-dependent modulation of heparan sulfate structure and function. Culturally sensitive interventions are needed to assist Mexican American (MA) patients with cancer and their family members in managing their care, navigating the healthcare system, and decreasing disparities in healthcare outcomes for Hispanics with cancer. Half-Sandwich Metal Carbonyl Complexes as Precursors to Functional Materials: From a Near-Infrared-Absorbing Dye to a Single-Molecule Magnet. Hence, a smaller spleen size can theoretically improve the outcome after transplantation. The acetone concentrations in venous blood (CB) and exhaled alveolar air (CA) at 1 minute after the end of the work shift were selected as biological indicators of exposure because they were predicted to decrease rapidly at the end of exposure and become relatively stable after 1 minute.

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These functions are connected by the organometallic chemistry of the MNR2BH3 group. 3-Hydroxy monocarboxylic acids ranging from 3-hydroxyhexanoic acid to 3-hydroxyhexadecanoic acid were synthesized. Since many viruses are known to target IRF-3 to inhibit the induction of IFN-beta mRNA, we analyzed the status of IRF-3 in infected cells. There was a very strong dose-response relation between frequency is biaxin a form of penicillin of bird attack and illness. Protein Alpha Shape (PAS) Dock: a new gaussian-based score function suitable for docking in homology modelled protein structures.

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We describe the standardized technique of left internal mammary artery grafting to the left anterior descending coronary artery, off-pump through a left inferior J-hemisternotomy (JOPCAB). It is predicted that mutations at one end of the helix should have very small effects on the stabilization of charges at the opposite terminus. The mutant did not produce oxalic acid and exhibited a modified regulation of the production of some secreted proteins (acid protease 1 and endopolygalacturonase 1). SZC015, a synthetic oleanolic acid derivative, induces both apoptosis and autophagy in MCF-7 breast cancer cells. A retrospective case note review of all children with MPS III in our institution was undertaken. Children aged 1-19 months were recruited from 2 childcare centers in Tacoma, Washington, from October 2008 through June 2009. Because of the multifocal lung involvement in these diseases, pulmonary metastases and infectious causes are often considered in the differential diagnosis.

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Among the structurally uncharacterized metzincin families are the pappalysins, of which the most thoroughly studied member is human pregnancy-associated plasma protein A (PAPP-A), a heavily glycosylated 170-kDa multidomain protein specifically cleaving insulin-like growth factor (IGF)-binding proteins (IGFBPs). Pooled RCTs: In patients with acute ischemic stroke, alteplase increases intracerebral hemorrhage. Somatic Embryogenesis in Peach-Palm (Bactris gasipaes) Using Different Explant Sources. The rs3752472 and rs650439 SNPs are related to the risk of calcium oxalate stones in Xinjiang Uyghurpeople, and might be one of the risk factors. Based on tandem affinity purification of Raa7 and mass spectrometry, Raa1 and Raa2 were identified as interacting partners of Raa7.

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Present study demonstrates the feasibility of structural modifications for improving in vivo tumor uptake of hypoxia detecting radiopharmaceuticals. The vasodilators PGI2 and PGE2 as well as the vasoconstrictors PGD2, PGF2alpha, and 11,9-epoxymethano-PGH2, a PG endoperoxide analogue with biological properties similar to thromboxane (TX) A2, inhibited the anaphylactic coronary constriction without affecting release of LTC4-like immunoreactivity. This article evaluates the intersection of air pollution and outdoor exercise and provides a discussion of issues related to its public health impact in China, where efforts to promote a healthy lifestyle may be adversely affected by the ambient air pollution that has accompanied rapid economic development and urbanization. We explored the immunoincompetence of mice undergoing a chronic graft-vs-host reaction (GVHR) across minor histocompatibility barriers. Multiple-dose efficacy comparison of the two topical carbonic anhydrase inhibitors sezolamide and MK-927. Confirming the diagnosis of acute transection of the descending aorta can be problematic. Primary cutaneous cryptococcosis successfully managed by surgical debridement and liposomal amphotericin B/flucytosine therapy. Among the most important are the Leu-CAMs or the CD11/CD18 integrin receptors, and their adhesion ligands ICAM-1 (CD54) and ICAM-2. Impact of rotator cuff surgery on postoperative sporting activity. Cephalexin in serum, dialysate and urine of patients with renal diseases.

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