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Alfazosin (Doxazosin)

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Alfazosin is a prescription drug indicated for the treatment of hypertension, to lower blood pressure. Lowering blood pressure reduces the risk of fatal and nonfatal cardiovascular events. These benefits have been seen in controlled trials of antihypertensive drugs from a wide variety of pharmacologic classes, including this drug.

Other names for this medication:
Alfazosin, Doxacard, Doxapress, Doxazosin, Duracard, Duraten

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Also known as: Doxazosin


Alfazosin (doxazosin) is an alpha-adrenergic (AL-fa ad-ren-ER-jik) blockers. Doxazosin relaxes your veins and arteries so that blood can more easily pass through them. It also relaxes the muscles in the prostate and bladder neck, making it easier to urinate.

Alfazosin is used to treat hypertension (high blood pressure), or to improve urination in men with benign prostatic hyperplasia (enlarged prostate).

Alfazosin XL, the extended-release form of this medicine, is used to treat benign prostatic hyperplasia and should not be used to treat hypertension.


Usual Adult Dose for Hypertension:

Initial dose: 1 mg orally once a day. Maintenance dose: 1 to 16 mg orally once a day.

Usual Adult Dose for Benign Prostatic Hyperplasia:

Initial dose: Immediate-release: 1 mg orally once a day. Extended-release: 4 mg orally once a day with breakfast Maintenance dose: Immediate-release: 1 to 8 mg orally once a day. Extended-release: 4 to 8 mg orally once a day with breakfast. Depending on the patient's symptomatic response and tolerability, the dose may be increased to 8 mg (the maximum recommended dose). The recommended titration interval is 3 to 4 weeks. If switching from immediate-release to extended-release tablets, therapy should be initiated with the lowest dose (4 mg once daily). Prior to starting therapy with Alfazosin extended-release tablets, the final evening dose of immediate-release tablets should not be taken. If Alfazosin extended-release tablets are discontinued for several days, therapy should be restarted using the 4 mg once daily dose.

Usual Geriatric Dose for Hypertension:

Initial dose: 0.5 mg orally once a day.

Detailed Alfazosin dosage information


If you overdose Alfazosin and you don't feel good you should visit your doctor or health care provider immediately.


Store at room temperature below 30 degrees C (86 degrees F) away from moisture and heat. Throw away any unused medicine after the expiration date. Keep out of the reach of children.

Side effects

The most common side effects associated with Alfazosin are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.


Alfazosin may impair your thinking or reactions. Be careful if you drive or do anything that requires you to be alert.

Avoid getting up too fast from a sitting or lying position, or you may feel dizzy. Get up slowly and steady yourself to prevent a fall.

To prevent dizziness, avoid standing for long periods of time or becoming overheated during exercise and in hot weather.

Drinking alcohol with this medicine can cause side effects.

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Enhancing effect of alpha-monoisostearyl glyceryl ether on the percutaneous penetration of indomethacin through excised rat skin. A concomitant increase in invasiveness of the Cx 26-expressing cells by the treatment was also observed in an in vitro assay with Matrigel matrix. Thirteen cases with coexistent vulvar lichen sclerosus and oral lichen planus were identified, of which five had oral biopsies. Systematic assessment of clinical outcomes and toxicities of proton radiotherapy for reirradiation. The artemether-damaged schistosomes also have decreased activities of a number of enzymes and enzyme systems, including glycolysis. E36 cells that were heat-treated in the presence of N-acetyl-L-leucyl-L-leucinyl-norleucinal did not lose their connexin43. Persistent hyperactivity following a single intracerebroventricular dose of ouabain. Seventy patients with morbid obesity were submitted to laparotomic resectional gastric bypass and an omentectomy was randomly performed in some patients.

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Orthopedic surgery at a MASH deployed to the former Yugoslavia in support of the United Nations Protection Force. This could be attributed to increased autoreceptor-mediated inhibition of DA release in caudate-putamen slices but not in the prefrontal cortex. Tuberculosis among allogeneic bone marrow transplant recipients in India. Twenty-six left-sided thoracoscopic splanchnicectomies were performed. The problem can be solved with reasonable accuracy when there are areas of void in the victim that are adjacent to the area struck by pellets. Two distinct genetic lineages are evident, which may be defined by geographical and host associations. Retardation capacity of organophilic bentonite for anionic fission products. To investigate the clinical significance of pannus on cardiac computed tomography (CT) in patients with a prosthetic MV.

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To investigate the association of ghrelin gene polymorphisms with metabolic syndrome in Han Nationality Chinese. Calcific tendinitis of the rotator cuff associated with intraosseous loculation: Two case reports. Recent studies with animal models of accelerated aging have unveiled some mechanisms that also operate in physiological aging. SE synergistically enhanced the superoxide anion and hydroxyl radical-scavenging activity of vitamin C. Economic analysis of amifostine as adjunctive support for patients with advanced head and neck cancer: preliminary results from a randomized phase II clinical trial from Germany. Role of lipophilicity and hydrogen peroxide formation in the cytotoxicity of flavonols. We documented significant clinical improvement using fascia lata allograft in the repair of massive irreparable r-c tear, acting as scaffold to bridge the defect, enhancing the healing at the repair site. We have reviewed the clinical charts of 28 patients diagnosed with cardiac myxomas seen at our centre in the last 20 years.

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Intraperitoneal administration of poly(I:C) with polyethylenimine leads to significant antitumor immunity against murine ovarian tumors. Cytotoxin point mutants from the recombinant gene carrying substitutions in the domain were characterized in terms of inhibiting the binding of radioiodinated natural cytotoxin to rat erythrocyte and producing cytotoxic effects in human granulocytes. A prepared airway practitioner performs safe airway management, displaying skill, knowledge, and a full awareness of human factors, within a culture of safety. Fibrin formation induced by tumor procoagulants enhances urokinase activity produced by mammary carcinoma cells. Therefore, an osteoporotic vertebral fracture can sometimes cause neurologic complications.

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