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Alfazosin (Doxazosin)
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Alfazosin

Alfazosin is a prescription drug indicated for the treatment of hypertension, to lower blood pressure. Lowering blood pressure reduces the risk of fatal and nonfatal cardiovascular events. These benefits have been seen in controlled trials of antihypertensive drugs from a wide variety of pharmacologic classes, including this drug.

Other names for this medication:
Alfazosin, Doxacard, Doxapress, Doxazosin, Duracard, Duraten

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Also known as: Doxazosin

Description

Alfazosin (doxazosin) is an alpha-adrenergic (AL-fa ad-ren-ER-jik) blockers. Doxazosin relaxes your veins and arteries so that blood can more easily pass through them. It also relaxes the muscles in the prostate and bladder neck, making it easier to urinate.

Alfazosin is used to treat hypertension (high blood pressure), or to improve urination in men with benign prostatic hyperplasia (enlarged prostate).

Alfazosin XL, the extended-release form of this medicine, is used to treat benign prostatic hyperplasia and should not be used to treat hypertension.

Dosage

Usual Adult Dose for Hypertension:

Initial dose: 1 mg orally once a day. Maintenance dose: 1 to 16 mg orally once a day.

Usual Adult Dose for Benign Prostatic Hyperplasia:

Initial dose: Immediate-release: 1 mg orally once a day. Extended-release: 4 mg orally once a day with breakfast Maintenance dose: Immediate-release: 1 to 8 mg orally once a day. Extended-release: 4 to 8 mg orally once a day with breakfast. Depending on the patient's symptomatic response and tolerability, the dose may be increased to 8 mg (the maximum recommended dose). The recommended titration interval is 3 to 4 weeks. If switching from immediate-release to extended-release tablets, therapy should be initiated with the lowest dose (4 mg once daily). Prior to starting therapy with Alfazosin extended-release tablets, the final evening dose of immediate-release tablets should not be taken. If Alfazosin extended-release tablets are discontinued for several days, therapy should be restarted using the 4 mg once daily dose.

Usual Geriatric Dose for Hypertension:

Initial dose: 0.5 mg orally once a day.

Detailed Alfazosin dosage information

Overdose

If you overdose Alfazosin and you don't feel good you should visit your doctor or health care provider immediately.

Storage

Store at room temperature below 30 degrees C (86 degrees F) away from moisture and heat. Throw away any unused medicine after the expiration date. Keep out of the reach of children.

Side effects

The most common side effects associated with Alfazosin are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.

Contraindications

Alfazosin may impair your thinking or reactions. Be careful if you drive or do anything that requires you to be alert.

Avoid getting up too fast from a sitting or lying position, or you may feel dizzy. Get up slowly and steady yourself to prevent a fall.

To prevent dizziness, avoid standing for long periods of time or becoming overheated during exercise and in hot weather.

Drinking alcohol with this medicine can cause side effects.

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To analyse the prevalence of myths among women regarding growth and health-related issues of children, and to study the impact of basic demographic factors in this regard. Weaning should be commenced by six months of age, but not earlier than 17 weeks. Wild mammal trypanosomiasis in French Guyana: practical implications for the presence of Trypanosoma rangeli. australis, with few relic populations remaining along the Atlantic coastline of the United States, particularly in the Virginia portion of the Chesapeake Bay. Impaired activity of the pathway might cause age-related perturbations of lipid homeostasis in the outer retina and thus may contribute to disease development and/or progression. Quantification of tumor angiogenesis may allow selection of the type of treatment for bladder cancer patients. In the present study, single factor and orthogonal experiments have been carried out to optimize the formulation of preparing CBSA. However, when asymmetry scores were pooled over the five bristle characters which individually exhibited fluctuating asymmetry, no significant differences were found between any genotypes.

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Angiogenesis relies on specialized endothelial tip cells to extend toward guidance cues in order to direct growing blood vessels. To characterize the samples fully, we have employed several complementary optical techniques: total diffuse transmission, total diffuse reflection, coherent transmission, and time-resolved speckle interferometry. A high-resolution phylogeny of the polar bear patriline shows two highly divergent Y chromosome lineages, obtained from analysis of the identified Y scaffolds in 12 previously published male polar bear genomes. Genetic tests showed the deletion of both pfhrp2 and pfhrp3 genes. Addition of unesterified arachidonic acid directly to cultured myocytes caused marked cytotoxicity and lipid peroxidation which were prevented by vitamin E or desferrioxamine. Palladium(II)-catalyzed direct alkenylation and arylation of arenes: removable 2-pyridylsulfinyl group assisted C-H bond activation. The addition of hematopoietic stem cell transplants (HSCT) has allowed further treatment intensification and provided the benefit of graft-versus-leukemia (GVL) effect. The major part of genes encoded cytokines, growth factors and chemokines. At 18 months, practitioners completed a recalibration exercise with a similar format with a total of 32 diagnoses.

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To investigate the association of ghrelin gene polymorphisms with metabolic syndrome in Han Nationality Chinese. Calcific tendinitis of the rotator cuff associated with intraosseous loculation: Two case reports. Recent studies with animal models of accelerated aging have unveiled some mechanisms that also operate in physiological aging. SE synergistically enhanced the superoxide anion and hydroxyl radical-scavenging activity of vitamin C. Economic analysis of amifostine as adjunctive support for patients with advanced head and neck cancer: preliminary results from a randomized phase II clinical trial from Germany. Role of lipophilicity and hydrogen peroxide formation in the cytotoxicity of flavonols. We documented significant clinical improvement using fascia lata allograft in the repair of massive irreparable r-c tear, acting as scaffold to bridge the defect, enhancing the healing at the repair site. We have reviewed the clinical charts of 28 patients diagnosed with cardiac myxomas seen at our centre in the last 20 years.

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Intraperitoneal administration of poly(I:C) with polyethylenimine leads to significant antitumor immunity against murine ovarian tumors. Cytotoxin point mutants from the recombinant gene carrying substitutions in the domain were characterized in terms of inhibiting the binding of radioiodinated natural cytotoxin to rat erythrocyte and producing cytotoxic effects in human granulocytes. A prepared airway practitioner performs safe airway management, displaying skill, knowledge, and a full awareness of human factors, within a culture of safety. Fibrin formation induced by tumor procoagulants enhances urokinase activity produced by mammary carcinoma cells. Therefore, an osteoporotic vertebral fracture can sometimes cause neurologic complications.

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