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Alernex (Fexofenadine)
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Alernex

Alernex is an effective medical drug for allergy caused by chemical histamine which is formed in our body naturally and reacts to the external irritants causing the allergic reaction. Alernex blocks the production and increased activity of histamine receptors as a result of which there is a reduction of the response reaction to the external irritants and the main symptoms of allergy are reduced. This drug helps to reduce cold, lacrimation, sneezing, itching, edema and other allergic symptoms.

Other names for this medication:
Afexdine, Alafex, Alernex, Alfexo, Allegix, Allofex, Fenax, Fendosh, Fexise, Fexocare, Fexodin, Fexodis, Fexofen, Fexokast, Fexoquin, Fexoquit, Fexor, Fexoriv, Fexot, Fexotec, Fexozide, Histagra, Histakind, Madexa, Monhale, Montair, Nexofex, Rafen

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Also known as: Fexofenadine

Description

Cough/cold combinations are used mainly to relieve the cough due to colds, influenza, or hay fever. They are not to be used for the chronic cough that occurs with smoking, asthma, or emphysema or when there is an unusually large amount of mucus or phlegm (pronounced flem) with the cough.

Cough/cold combination products contain more than one ingredient. For example, some products may contain an antihistamine, a decongestant, and an analgesic, in addition to a medicine for coughing. If you are treating yourself, it is important to select a product that is best for your symptoms. Also, in general, it is best to buy a product that includes only those medicines you really need. If you have questions about which product to buy, check with your pharmacist.

Since different products contain ingredients that will have different precautions and side effects, it is important that you know the ingredients of the medicine you are taking. The different kinds of ingredients that may be found in cough/cold combinations include:

Antihistamines—Antihistamines are used to relieve or prevent the symptoms of hay fever and other types of allergy. They also help relieve some symptoms of the common cold, such as sneezing and runny nose. They work by preventing the effects of a substance called histamine, which is produced by the body. Some examples of antihistamines contained in these combinations are:

Bromodiphenhydramine Brompheniramine Carbinoxamine Chlorpheniramine Dexchlorpheniramine Diphenhydramine Doxylamine Phenindamine Pheniramine Phenyltoloxamine Pyrilamine Promethazine Triprolidine

Decongestants—Decongestants produce a narrowing of blood vessels. This leads to clearing of nasal congestion. However, this effect may also increase blood pressure in patients who have high blood pressure. These include:

Ephedrine Phenylephrine Pseudoephedrine

Antitussives—Antitussives help relieve coughing and are some contain a narcotic. These antitussives act directly on the cough center in the brain. Narcotics may become habit-forming, causing mental or physical dependence, if used for a long time. Physical dependence may lead to withdrawal side effects when you stop taking the medicine.

Narcotic antitussives Codeine Dihydrocodeine Hydrocodone Hydromorphone

Non-narcotic antitussives Carbetapentane Caramiphen Dextromethorphan

Expectorants—Expectorants work by loosening the mucus or phlegm in the lungs. The main expectorant used in cough and cold medicines is guaifenesin. Other ingredients added as expectorants (for example, ammonium chloride, calcium iodide, iodinated glycerol, ipecac, potassium guaiacolsulfonate, potassium iodide, and sodium citrate) have not been proven to be effective. In general, the best thing you can do to loosen mucus or phlegm is to drink plenty of water.

Analgesics—Analgesics are used in these combination medicines to help relieve the aches and pain that may occur with the common cold. These include:

Acetaminophen Aspirin Other salicylates such as salicylamide and sodium salicylate

The use of too much acetaminophen and salicylates at the same time may cause kidney damage or cancer of the kidney or urinary bladder. This may occur if large amounts of both medicines are taken together for a long time. However, taking the recommended amounts of combination medicines that contain both acetaminophen and a salicylate for short periods of time has not been shown to cause these unwanted effects.

Anticholinergics—Anticholinergics, such as homatropine may help produce a drying effect in the nose and chest.

These cough and cold combinations are available both over-the-counter (OTC) and with your doctor's prescription.

Do not give any over-the-counter (OTC) cough and cold medicine to a baby or child under 4 years of age. Using these medicines in very young children might cause serious or possibly life-threatening side effects .

Dosage

Usual Adult Dose for Allergic Rhinitis:

Usual Pediatric Dose for Allergic Rhinitis: 13 years or older: one tablet (180 mg/240 mg) orally once a day.

Detailed Alernex-D 24 Hour dosage information

Overdose

If you overdose Generic Alernex and you don't feel good you should visit your doctor or health care provider immediately.

Storage

Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing.

Keep out of the reach of children.

Do not keep outdated medicine or medicine no longer needed.

Ask your healthcare professional how you should dispose of any medicine you do not use.

Detailed Alernex ODT dosage information

Side effects

The most common side effects associated with Alernex are:

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Effects of low density lipoprotein and oxidized low density lipoprotein on the cytotoxic activity of Asp-hemolysin to murine macrophages. Cervical cancer cells suppress effector functions of cytotoxic T cells through the adenosinergic pathway. Additionally, immunoadsorbed GLUT4 vesicles were found to catalyze palmitoylation of proteins when incubated with labeled palmitate, a pathway that requires palmitate esterification with CoA. We aim at characterizing the complex organization and dynamics of the plasma membrane at single-molecule level, by developing analytic tools dedicated to Single-Particle Tracking (SPT) at high density: Multiple-Target Tracing (MTT). Weight bearing and velocity in trans-tibial and trans-femoral amputees.

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The authors, journal, date and country of publication, patient group studied, study type, relevant outcomes and results of these papers are tabulated. The uaYc462 allele was mapped physically in relation to known loss-of-function alleles and sequenced. Prominent expression of EphA4, EphA7, and ephrin-A ligands was detected in muscle during embryonic development. Thirty-seven children (aged 0.5-7 years) without known endocrine disease or cranial neoplasms undergoing outpatient magnetic resonance imaging, under general anaesthesia for investigation of nonacute problems in a tertiary referral paediatric hospital. The low radiation dose allows multiple imaging sessions to be performed with a cumulative X-ray dosage far below LD50.

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Graft density as assessed by microcomputed tomographic scans increased significantly in vivo, yet there were no differences in mineralization by extracellular calcium measurements preimplantation and postimplantation. A randomized controlled clinical trial design with repeated measures 1 year apart. Neurochemical lateralisation has been demonstrated in dopaminergic systems in the rat brain, and it has been suggested that such lateralisation might contribute to asymmetric and emotional behaviour. Interfacial tension and rheology were investigated at a planar mineral oil/double distilled water interface is levlen a mini pill using a Wilhelmy plate method and an oscillatory ring surface rheometer, respectively. Imaging studies, and pathogenic and biopsy examinations can diagnose fungal infections, which can be effectively treated with antifungal agents such as Fluconazole, Voriconazole or Amphotericin B. In this study, Silastic, porcine dermis, and human dura mater blocks were bonded together for 10 and 30 minutes with AFTA-E or AFTA-A.

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