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Afeditab (Nifedipine)

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Afeditab is a calcium-channel blocker. It affects the amount of calcium found in your heart and muscle cells. This relaxes your blood vessels, which can reduce the amount of work the heart has to do. This medicine is used to treat chest pain caused by angina.

Other names for this medication:
Adefin, Adipine, Antrolin, Belnif, Calcheck, Calcibloc, Conetrin, Coracten, Coral, Cordilat, Depin, Depine, Fedip, Hexadilat, Macorel, Nidilat, Nifebene, Nifecap, Nifed, Nifedicor, Nifedip, Nifedipina, Nifehexal, Nifeslow, Nifestad, Ospocard, Tenif, Valni

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Also known as: Nifedipine


Nifedipine is used alone or together with other medicines to treat severe chest pain (angina) or high blood pressure (hypertension). High blood pressure adds to the workload of the heart and arteries. If it continues for a long time, the heart and arteries may not function properly. This can damage the blood vessels of the brain, heart, and kidneys, resulting in a stroke, heart failure, or kidney failure. High blood pressure may also increase the risk of heart attacks. These problems may be less likely to occur if blood pressure is controlled.

Nifedipine is a calcium channel blocker. It works by affecting the movement of calcium into the cells of the heart and blood vessels. As a result, nifedipine relaxes blood vessels and increases the supply of blood and oxygen to the heart while reducing its workload.

This medicine is available only with your doctor's prescription.


This section provides information on the proper use of a number of products that contain nifedipine. It may not be specific to Afeditab XL. Please read with care.

In addition to the use of this medicine, treatment for your high blood pressure may include weight control and changes in the types of foods you eat, especially foods high in sodium (salt). Your doctor will tell you which of these are most important for you. You should check with your doctor before changing your diet.

Many patients who have high blood pressure will not notice any signs of the problem. In fact, many may feel normal. It is very important that you take your medicine exactly as directed and that you keep your appointments with your doctor even if you feel well.

Remember that this medicine will not cure your high blood pressure, but it does help control it. You must continue to take it as directed if you expect to lower your blood pressure and keep it down. You may have to take high blood pressure medicine for the rest of your life. If high blood pressure is not treated, it can cause serious problems such as heart failure, blood vessel disease, stroke, or kidney disease.

Swallow the extended release tablet whole. Do not break, crush, or chew it. It is best to take this tablet on an empty stomach.

If you are taking the extended-release tablets, part of the tablet may pass into your stool after your body has absorbed the medicine. This is normal and nothing to worry about.

The dose of this medicine will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of this medicine. If your dose is different, do not change it unless your doctor tells you to do so.

The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.

For treatment of chest pain or high blood pressure: For oral dosage form (capsules): Adults—At first, 10 milligrams (mg) three times a day. Your doctor may increase your dose as needed. Children—Use and dose must be determined by your doctor. For oral dosage form (extended-release tablets): Adults—At first, 30 or 60 milligrams (mg) once a day. Your doctor may increase your dose as needed. However, the dose is usually not more than 90 mg once a day. Children—Use and dose must be determined by your doctor.


If you overdose Afeditab and you don't feel good you should visit your doctor or health care provider immediately.


Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing.

Keep out of the reach of children.

Do not keep outdated medicine or medicine no longer needed.

Ask your healthcare professional how you should dispose of any medicine you do not use.

Detailed Nifedipine dosage information

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Appropriate studies have not been performed on the relationship of age to the effects of nifedipine in the pediatric population. Safety and efficacy have not been established.

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Clinical analysis of voice change as a parameter of premenstrual syndrome. A 25-year-old man undergoing splenectomy at 3 years of age to treat idiopathic thrombocytopenic purpura but no history of Streptococcus pneumonia vaccination, and reporting high fever, nausea, and headache developed purpura, confusion, and hypotension the next day and was admitted. Nanoparticle-wall collision in a laminar cylindrical liquid jet. The proportion of patients in whom blood cultures were obtained prior to antibiotic administration in the pre- (October 2007-March 2008) and postintervention (April 2008-September 2008) periods were compared. We calculated prevalence ratios (PRs) adjusted for age, sex, race/ethnicity, education, income, employment, and health insurance. Pretreatment of the hippocampal slice cultures with NMDA receptor antagonist or calpain inhibitors effectively prevented the UCB-induced impairment of LTP and LTD. (1)H and (13)C NMR confirm the extent of modification and the degree of branching in the different generations.

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131I-meta-iodobenzylguanidine scintigraphy was used in all patients between 1984 and 1987, but selectively after that. The rapid evolution of these structures appears to contribute to the phenotypic flexibility of pathogens. Its identification in full-term placental tissue has no relation to the type of delivery in childbirth. The cortical thickness-diffusion tensor imaging correlations showed significant group differences in the posterior cingulate gyrus, precuneus, and superior frontal gyrus. Dimethyl fumarate influences innate and adaptive immunity in multiple sclerosis. The present review is based on the identification of four major environmental crises that have been approached from a biological oceanographic viewpoint. Chapters in the history of psychiatry in Palestine and its neighborhood. However, it is unclear whether the impact of unpredictability on the ERN is also observed in children and adolescents.

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infusion of urodilatin at a dose of 30 ng kg-1 min-1 were studied in a patient with congestive heart failure. This hyperalgesia could be reversed by pretreatment of rat with NS-398 or JTE-522, but not with mofezolac. The bovine parasite, Theileria annulata has a complex life-cycle involving the expression and repression of genes during development of its morphologically distinct life-cycle stages. Traumatic ulcerative granuloma with stromal eosinophilia: a malignant-appearing benign lesion. In particular, there is a lack of automated homology-based approaches that produce high-quality TEs. This study examined the effect of isolation-rearing in the Lister hooded rat on extracellular 5-hydroxytryptamine in the medial nucleus accumbens following footshock and in relation to a conditioned emotional response. Traditional tests and job simulations: minority and majority performance and test validities. Acute sensorineural hearing loss following intravenous ketoralac administration. Autophagy and cell growth can inhibit one another through a variety of direct and indirect mechanisms, and can be independently regulated by common signaling pathways. Terahertz (THz) time-domain spectroscopy was used to investigate the absorption characteristics of a rotationally oriented sucrose single crystal in the 0.3 - 3.0 THz frequency range.

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Audit data were collected from 18-old-age psychiatry units across Australia. The study website, the SmokingZine, was originally developed and tested in Canadian youth, then adapted to be appropriate for American Indian youth. These insights may contribute to modification of hospice care systems so health professionals will be more responsive to the needs of their dying patients to retain control and die with dignity and help health professionals achieve the proposed outcome of hospice care. Viral immediate-early (IE) genes generally encode regulatory proteins that are critical for viral replication. Therapeutic considerations and areas for further research are also discussed. Effects of three low-molecular-weight organic acids (LMWOAs) and pH on the mobilization of arsenic and heavy metals (Cu, Pb, and Zn) from mine tailings. Geographical distribution of Biomphalaria snails in the State of Minas Gerais, Brazil. Radiolabeled simian CMV (SCMV) BPP, synthesized in vitro, bound to SCMV B-capsids, and C-capsids to a lesser extent, following incubation with either isolated capsids or lysates of infected cells. Induction of apoptosis in proinflammatory cells including eosinophils at the airway may have a beneficial effect on suppressing airway hyperresponsiveness.

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We suggest that future studies on the eggshell microbes should investigate the interaction among the microbes, because the incubation and/or environmental factors such as urbanization or climate condition can influence the dynamic interactions among the microbes on the eggshells which can further determine the breeding success of the parents. Among eight genes controlling agronomic traits, GN1a and GS3 were partially fixed in the genome of northern japonica cultivars. A Sudanese man presented with torticollis and deviation of the uvula due to paresis of N. Primary pleuropulmonary tumors are rare but clinical presentation can be varied and delay in diagnosis is common. To develop population-based age- and gender-specific normative values for the pain, stiffness, and physical function subscales of the AUSCAN Index for benchmarking applications. Connexin43 (Cx43) generates intercellular gap junction channels involved in, among others, cardiac and brain function. Further studies are needed to help integrate the latest findings into clinically useful tools for personalized medicine. The increase in NK cell death was associated with an increase in tumor necrosis factor-alpha (TNF-alpha) secretion, and concomitant inhibition of nuclear factor kappa B (NFkappaB) activation and the induction of c-jun N-terminal kinase (JNK) activity in NK cells treated with the combination of anti-class I and anti-CD16 antibodies.

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The PCR method provided rapid and reliable results for the identification of fragile X negative and positive patients. Does early hyperbaric oxygen therapy prevent extremity necrosis in Nicolau syndrome?. The predicted amino acid sequence of the protein has identifiable features suggesting that it might be a motor protein with an amino-terminal hydrolytic domain attached to a long coiled coil stalk. Multidrug resistance proteins MRP3, MRP1, and MRP2 in lung cancer: correlation of protein levels with drug response and messenger RNA levels. Phase I/II trial of hyperfractionated radiation and chemotherapy followed by surgery in stage III lung cancer. Self-injury is a complex and poorly understood behavior observed in people with psychopathology or neurodevelopmental disorders (NDD). MAG/NF200 staining demonstrated reduced myelination and axonal counts in the corpus callosum of IUGR animals.

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We investigate the loss of chaos synchronization in coupled chaotic systems without symmetry from the point of view of bifurcations of unstable periodic orbits embedded in the synchronous chaotic attractor (SCA). Using a DNA probe based on the coding region of the receptor, Northern blot and RT-PCR analysis of RNA isolated from different cell types showed C1qRP expression in cells of myeloid origin and in endothelial cells, but not in cells of lymphoid origin nor in the HeLa epithelial-like cell line or iliac artery smooth muscle cells. The functional test reflected functional limitations in obese women, revealing difficulties and perceived pain in ADL. The possible candidates were determined via comparative sequence and structural analysis of the substrate channel and the heme region of coral cAOSs and C. Myc-transformed follicles also grow much more rapidly than normal follicles. In this study, participants pointed to randomly lateralized targets under full viewing conditions, either with or without a single distractor present.

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To assess walking ability of spinal cord injury (SCI) patients and observe its correlation with functional and neurological outcomes. Ultrasonic modulation of scattered light in turbid media and a potential novel tomography in biomedicine. The addition of IL15 under hyperthermic conditions resulted in an important increase in protein synthesis with no changes in protein degradation, except when cells overexpressed PPARdelta. In 1997, pathogenic avian influenza A/Hong Kong/97 (H5N1) viruses emerged as a pandemic threat to human beings. Production of tumor necrosis factor-alpha (TNF-alpha) increased 6-24h after reperfusion in both lobes. Performances have been evaluated using Monte-Carlo simulations for various labeling density and noise values, which typically represent the two major limitations for parallel measurements at high spatiotemporal resolution. VST provides more power to detect differentially expressed genes than a log2 transformation. By utilizing the anchoring ability of the thiocarbonylthio end group, the dispersion polymerization of N-vinyl pyrrolidone was successfully achieved in scCO2 leading to high yields of well-defined spherical polymer particles. The goal of the present study was to investigate the effect of this treatment on the serum concentrations of calcium, inorganic phosphorus and magnesium in parturient cows.

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A 45-year-old male with relapsed APL was commenced on a treatment schedule of all-trans-retinoic acid 20mg four times a day for 14 days concurrent with a 10mg intravenous infusion of arsenic trioxide for 28 days. Diabetes in our rats was associated with weight loss, increased urinary calcium excretion and reduced plasma osteocalcin levels. Drag reducing polymers (DRPs) are blood-soluble macromolecules that can, in nanomolar concentrations, increase tissue perfusion, decrease vascular resistance and decrease near-wall microvascular concentration of neutrophils and platelets thereby possibly reducing the inflammatory microenvironment. These findings suggest that diurnal cortisol may be a key biological pathway through which social relationships affect long-term health. The expression pattern of IGFBP-2 mRNA was similar during different stages of testis and ovary.

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Architectonics of Bifidobacteria populations: submicroscopic aspect of cell cohesion in Bifidobacterium adolescentis and Bifidobacterium bifidum. The test was also negative for the six patients with advanced cutaneous melanoma. Using the Alberta Provincial Project for Outcomes Assessment in can diflucan treat yeast infection on skin Coronary Heart Disease registry, 5,276 patients undergoing CABG surgery from September 2002 to August 2011 were identified. The stoichiometry of 2.6 trypsin molecules/1 precursor molecule indicates that processing is required to activate or expose all of the four trypsin inhibitory sites. Funisitis and risk for the development of neonatal respiratory distress syndrome. The process of re-closure involved a zipper-like (ventral to dorsal) closure in the transverse sections of neural tubes. In cases with abnormal CTG, ST analysis may improve consistency in clinical decision-making and decrease unnecessary interventions, but may also lead on rare occasions to unjustified decisions not to intervene.

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This approach improves the effectiveness of conventional treatments for subcutaneous tumors and avoids that solid lipid nanoparticles are rapidly cleared from the circulation following systemic administration. Central Nervous System MR and ophthalmologic evaluations were reviewed. SHP-1 therefore has the capacity to bind and potentially modulate the signaling effectors involved in activation of Ras, and accordingly, regulation of cellular transformation of BCR-ABL. A general theoretical approach, based on light and matter angular momentum conservation, shows that the optical alignment is due to the internal compensation between the transfer of the orbital and the spin part of angular momentum of the incident photons to the material. By using immunoprecipitation and Western blot analysis, sequential changes in the expression of both cyclin D1 and p21Waf1 were detected during the conversion of precrisis esophageal epithelial cells to immortalized HET-1A cells. We demonstrate the first electric field induced transverse deflection of a single-crystal, free-standing ZnO microbelt as a result of converse piezoelectric effect. Fetal liver cells are able to proliferate in cell culture and could therefore sustiva hiv pill present an alternative source of cells for transplantation. Addition of anti-estrogen therapy to anti-HER2 dendritic cell vaccination improves regional nodal immune response and pathologic complete response rate in patients with ERpos/HER2pos early breast cancer. Incidence of aspirin resistance in the patient group of a university hospital in Korea. The authors describe the first clinical trial with encapsulated cell biodelivery (ECB) implants that deliver nerve growth factor (NGF) to the cholinergic basal forebrain with the intention of halting the degeneration of cholinergic neurons and the associated cognitive decline in patients with Alzheimer disease (AD).

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A case of primary malignant melanoma of the female urethra is reported. Significant reductions in exercise HR were observed in the EG at each exercise level, confirming achievement of an aerobic conditioning effect. Diclofenac, aspirin and naproxen showed more potential to inhibit the growth of dermatophytes. Non-invasive treatments of luteinizing hormone-releasing hormone for inducing spermiation in American (Bufo americanus) and Gulf Coast (Bufo valliceps) toads. Three staff members, who had worked most closely with each resident for at least 3 months completed three questionnaires, including Quantitative and Qualitative compulsive behavior scales, and the Childhood Autism Rating Scale (CARS). Neuronal damage in glutaryl-CoA dehydrogenase deficiency (GDD) has previously been addressed to N-methyl-D-aspartate (NMDA) receptor-mediated neurotoxicity of the accumulating neurotoxic metabolite 3-hydroxyglutarate. Broad-spectrum antimicrobials and the treatment of serious bacterial infections: getting it right up front.

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In this sample, pain now was reduced more than pain best and pain worst. Moreover, positive effect of therapy was demonstrated that manifested in amelioration of memory disturbances in depression-like disorders in these behavioral tests. The ssDNA-binding affinity of this trimeric complex was 3 to 5-fold higher than hRPA14.32-(43-171) alone, suggesting a role for the C terminus of hRPA70 in ssDNA binding. Irregular cleavages, particularly embryo rolling, were more often seen in planar embryos. In women with female fetuses, we found lower serum levels of 7beta-OH-DHEA and higher androstenedione in smokers at the 37(th) week. The aim of the study was to estimate antioxidant status and reliable factors involved in antioxidant protection in children with nephrotic syndrome (NS). Intense exposure to light, robust metabolic activity, and high oxygen tension render the human eye particularly vulnerable to oxidative damage and the list of ophthalmological disorders implicating reactive oxygen and nitrogen species is rapidly expanding. Eleven aroma constituents were chosen from over 100 chemicals found in the samples to compare differences among various teas. The proposed concept can be used to realize various high performance tunable plasmonic devices such as isolators, switches and splitters for ultracompact integrated plasmonic circuits.

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Pregnancy in patients with transposition can you take zyrtec d with alcohol of great vessels corrected by the Mustard procedure. Effect of pancreatic secretory trypsin gene mutations on the development of chronic pancreatitis. As indicated by the earlier development of overstory basal area, coppice sites were also regenerating much faster. Because spinal AVFs are rarely reported, however, screening is not incorporated into current clinical recommendations for the treatment of patients with HHT. The role of MR-visible lipids in cancer diagnosis and the assessment of the treatment response in both animal models of cancer and human brain tumors is also discussed. Schistosomiasis is a tropical parasitic disease, caused by blood-dwelling worms of the genus Schistosoma. Only nine of 65 mutant proteins of AvrPto with amino acid substitutions, created in planta and in vitro, did not interact with Pto in the Gal4 yeast two-hybrid system, suggesting that AvrPto can tolerate many nonconservative substitutions and still interact with Pto. When flesinoxan was infused into the LC, no effects were seen in the PFC. Uninhibited contractions resolved in all patients postoperatively.

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Our algorithms show moderate to high PPVs for recurrence and metastases. The primary cilium functions as a mechanical and calcium signaling nexus. While comprehensive cancer registration data are available for some locations in India and Pakistan, the situation regarding other countries in South Asia is less clear. The authors report their experience at the Orthopaedic Clinic of the University of Parma regarding 20 cases of revision surgery by transfemoral approach using the Wagner long-stem cementless prosthesis for the treatment of prosthetic failure. However, the method is time-consuming when analyzing a large number of samples.

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Environmental design for end-of-life care: An integrative review on improving quality of life and managing symptoms for patients in institutional settings. A prospectively maintained database of patients undergoing TSSM and immediate breast reconstruction from 2005 to 2013 was reviewed. In addition, the two materials presented the same evolution with similar values in interleukin-1, inducible nitric oxide synthase, alkaline phosphatase, osteocalcin and bone sialoprotein gene expression at all culture times how to go off lexapro 10 mg . Chronic Auditory Toxicity in Late Preterm and Term Infants With Significant Hyperbilirubinemia. A number of the modified bicyclic peptides displayed much higher affinity towards matriptase-2 than towards the highly homologous matriptase-1.

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The presentation, surgical treatment, disease progression, and outcome of these patients were reviewed. Synthesis, biological evaluation and docking studies of novel benzopyranone congeners for their expected activity as anti-inflammatory, analgesic and antipyretic agents. In the liver of newborn animals solely the content of Fe, Cu and Zn was determined. However, the use of this VCS system had no influence on the recovery of graft function. Our results suggest that reverse docking is efficient for target fishing of compounds with known anti-tumor activities. Finally, Experiment 4 showed that reduced and unreduced primes facilitate upcoming low-frequency related words equally if the interstimulus interval is extended. The two methods are evaluated and compared using simulation studies and a real data set. The clinical course was uneventful, with the double-J stent left in place for 4 weeks. Pathologic examination of mediastinal lymph nodes (MLNs) after resection of non-small-cell lung cancer is critical in the determination of prognosis and postoperative management. Kinematic results presented in this case study illustrate evidence of excessive foot pronation throughout the stance phase of gait.

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