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Adiff (Adapalene)

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Adiff is an expensive drug used to treat mild to moderate acne. This drug is slightly more popular than comparable drugs. It is available in generic and brand versions. Over-the-counter Adiff is now available without a prescription.

Other names for this medication:
Aclene, Acneril, Acniriv, Adaferin, Adapalene, Adapen, Adaret, Adgraze, Adiff, Adina, Aditop, Alangel, Apalene, Apgel, Clinred, Daple, Deriva, Difra, Edplin, Faceclin, Labopene, Rozac, Soflene, Vandep, Zolvee

Similar Products:
Alprostadil, Caverta, Cipro, Anafranil, Fosamax, Loxitane, Pramace, Ketosis, Elixophyllin, Romizole, Spirotic, Duradiuret,

Also known as: Adapalene


Adapalene is used to treat acne. It works partly by keeping skin pores clear.

Adapalene is available only with your doctor's prescription.


Follow the directions for using this medicine provided by your doctor. Use Adiff exactly as directed. Adiff is best applied after washing and drying your skin. Apply a thin layer of gel to the affected areas once daily at bedtime. Avoid the eyes, lips and nose. Do not allow this preparation to come into contact with the mucous membranes (e.g. mouth, vagina, inside of nose etc.). Try not to touch the treated areas overnight. Do not use any harsh soaps or exfoliants while you are being treated with Adiff. Adiff should not be used on broken, sunburnt or infected skin. You may notice a slight change of colour of the skin you are applying this preparation to. This is only temporary and should return to normal soon after finishing treatment with Adiff. Continue using Adiff until no new acne spots appear. You may need to use it for several months. You should notice some clinical improvement after 4-8 weeks and more improvement after further use. There may be a worsening of acne during the first few weeks of therapy because Adiff promotes the growth of pimples that have begun to form but are not yet visible. Therefore, treatment should not be stopped if acne appears to be worsening. Use a sunscreen cream and wear protective clothing if exposure to strong or prolonged sunlight cannot be avoided. Weather extremes such as wind or cold may also be irritating.


If you overdose Adiff and you don't feel good you should visit your doctor or health care provider immediately.


Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing.

Keep out of the reach of children.

Do not keep outdated medicine or medicine no longer needed.

Detailed Adiff dosage information

Side effects

The most common side effects associated with Adiff are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.


There are no adequate studies in women for determining infant risk when using this medication during breastfeeding. Weigh the potential benefits against the potential risks before taking this medication while breastfeeding.

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