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Addos (Nifedipine)
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Addos

Addos is a drug that performs by relaxing the muscles inside the heart and blood vessels in order to enable easier blood flow. This enables the heart to have an easier time pumping blood. The active ingredient is nifedipine and it a part of a class of drugs called calcium channel blockers. The primary use of this medication is to help stop chest pain (angina) and help treat high blood pressure problems (hypertension). In addition to this it can also be used in order to heighten the supply of oxygen and blood to the heart and help with a specific blood circulation condition called Raynaud’s phenomenon.

Other names for this medication:
Addos, Anpect, Cardalin, Cardiosol, Cardipin, Carditas, Cardules, Casanmil, Cordalat, Corinfar, Emaberin, Fenidina, Ficard, Ficor, Milfadin, Nedipin, Nifecard, Nifedipina, Nifeslow, Nilol, Nipidin, Nyefax, Ospocard, Tensomax, Tredalat, Valni, Vasdalat

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Imdur, Theolair, Rocaltrol, Elocon, Lodine, Mysoline, Minipress, Avapro, Zocor, Tenil, Pronext, Pyrivin, Telsan, Mtronidazole, Promethegan, Arodol,

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Also known as: Nifedipine

Description

Nifedipine is used alone or together with other medicines to treat severe chest pain (angina) or high blood pressure (hypertension). High blood pressure adds to the workload of the heart and arteries. If it continues for a long time, the heart and arteries may not function properly. This can damage the blood vessels of the brain, heart, and kidneys, resulting in a stroke, heart failure, or kidney failure. High blood pressure may also increase the risk of heart attacks. These problems may be less likely to occur if blood pressure is controlled.

Nifedipine is a calcium channel blocker. It works by affecting the movement of calcium into the cells of the heart and blood vessels. As a result, nifedipine relaxes blood vessels and increases the supply of blood and oxygen to the heart while reducing its workload.

This medicine is available only with your doctor's prescription.

Dosage

This section provides information on the proper use of a number of products that contain nifedipine. It may not be specific to Addos PA 20. Please read with care.

In addition to the use of this medicine, treatment for your high blood pressure may include weight control and changes in the types of foods you eat, especially foods high in sodium (salt). Your doctor will tell you which of these are most important for you. You should check with your doctor before changing your diet.

Many patients who have high blood pressure will not notice any signs of the problem. In fact, many may feel normal. It is very important that you take your medicine exactly as directed and that you keep your appointments with your doctor even if you feel well.

Remember that this medicine will not cure your high blood pressure, but it does help control it. You must continue to take it as directed if you expect to lower your blood pressure and keep it down. You may have to take high blood pressure medicine for the rest of your life. If high blood pressure is not treated, it can cause serious problems such as heart failure, blood vessel disease, stroke, or kidney disease.

Swallow the extended release tablet whole. Do not break, crush, or chew it. It is best to take this tablet on an empty stomach.

If you are taking the extended-release tablets, part of the tablet may pass into your stool after your body has absorbed the medicine. This is normal and nothing to worry about.

The dose of this medicine will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of this medicine. If your dose is different, do not change it unless your doctor tells you to do so.

The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.

For treatment of chest pain or high blood pressure: For oral dosage form (capsules): Adults—At first, 10 milligrams (mg) three times a day. Your doctor may increase your dose as needed. Children—Use and dose must be determined by your doctor. For oral dosage form (extended-release tablets): Adults—At first, 30 or 60 milligrams (mg) once a day. Your doctor may increase your dose as needed. However, the dose is usually not more than 90 mg once a day. Children—Use and dose must be determined by your doctor.

Overdose

If you overdose Addos and you don't feel good you should visit your doctor or health care provider immediately.

Storage

Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing.

Keep out of the reach of children.

Do not keep outdated medicine or medicine no longer needed.

Ask your healthcare professional how you should dispose of any medicine you do not use.

Detailed Nifedipine dosage information

Side effects

The most common side effects associated with Addos are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.

Contraindications

Tell your doctor if you have ever had any unusual or allergic reaction to this medicine or any other medicines. Also tell your health care professional if you have any other types of allergies, such as to foods, dyes, preservatives, or animals. For non-prescription products, read the label or package ingredients carefully.

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The purpose of this study was to develop three novel advanced suturing tasks with assessment metrics and to collect validity evidence for their measures of suturing skill. Transcatheter arterial chemoembolization (TACE) is a routine treatment for hepatocellular carcinoma in cirrhotic patients. Microtubule-interfering agents also activated both Ras and apoptosis signal-regulating kinase (ASK1) and coexpression of dominant negative Ras and dominant negative apoptosis signal-regulating kinase exerted individual and additive inhibition of JNK/SAPK activation by microtubule-interfering agents. A combination of atorvastatin and amlodipine causes sympathoinhibition via an anti-oxidant in the RVLM and improves cognitive dysfunction via an anti-oxidant in the hippocampus in hypertensive rats, independent of the blood pressure-lowering effect. Follow-up of a major linkage peak on chromosome 1 reveals suggestive QTLs associated with essential hypertension: GenNet study. Whereas environmental stressors, such as temperature, oxidative stress, and osmotic stress, can also damage proteins, it is not known whether aging and the environment impact protein folding in the same or different ways. We have identified a 195-kD protein that coimmunoprecipitates with a class VI myosin, Drosophila 95F unconventional myosin. This paper provides a comprehensive editorial perspective on classical COI-related issues. At the same time, the periventricular areas of the brain, consisting of proliferating cells, are non-reactive for NSE. The present study aimed to characterize the prevalence and pattern of cardiac abnormalities and to test the additional diagnostic value of CMR in this patient population.

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Tibial nerve transcutaneous stimulation for refractory idiopathic overactive bladder in children and adolescents. Evaluation of personal and built environment attributes to physical activity: a multilevel analysis on multiple population-based data sources. We obtain an estimate of the twist-grain-boundary spacing and screw dislocation spacing in a boundary in terms of the macroscopic parameters, in reasonable agreement with experimental results. Successful PGD in patients with MEN has not yet been reported and has met with some early difficulties, but it is believed that this technique will eventually be successful for MEN and other hereditary endocrine disorders. Women undergoing tubal sterilization were more likely than women whose husbands underwent vasectomy to undergo hysterectomy within 5 years after sterilization, regardless of age at sterilization. Isolation of bacterial strains able to metabolize lignin from screening of environmental samples. Increased aortic pulse wave velocity (aPWV) and central BP are risk markers for cardiovascular disease. Fluorescence spectroscopy showed that much more dramatic changes were produced by urea denaturation than by pressure. When there is HDI in addition to HDD, the formulation is a hierarchical generalized linear model.

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Nevertheless, despite such biases, consistent differences are observed between European countries in the probability of survival following the diagnosis of a paediatric cancer. Although microRNAs regulate all the major biological mechanisms, their influence on tumor microenvironment is largely unexplored. Our study suggests that the inactivation of the MTS 1 gene may play an important role in esophageal carcinoma cell lines but may be less important in primary carcinomas of the human esophagus. Moreover, as nuclear aggregates became larger: (1) nearly all nuclei within active aggregates expressed mRNA and (2) local accumulation (mRNA per unit area) was elevated relative to single nuclei, while per nucleus mRNA production decreased. Hcy treatment also significantly increased intracellular reactive oxygen species H2O2, which coincided with the elimination of caspase 3 proenzyme levels and increased caspase 3 activity at the time of the appearance of apoptotic DNA fragmentation. Rivaroxaban: an oral direct factor Xa inhibitor for the prevention of thromboembolism. Exterior carpi radialis longus tendinoplasty for thumb basal joint arthritis. Meta-analysis methodology in the microbleeds field: The relevance of the clinical question and study quality in choosing the most appropriate model. Law in practice: obstacles to a smokefree workplace policy in bars serving Asian patrons. Hippocampal developmental vulnerability to methylmercury extends into prepubescence.

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Cycloheximide (CHI, 10 microg/ml), an inhibitor of protein synthesis, maximally increased IL-8 mRNA levels 30-fold in H292 cells. Postnatal distress is associated with body weight and shape concerns, with disordered eating before and during pregnancy, and with vomiting during pregnancy. Lipopolysaccharide-stimulated monocyte tissue factor assay showed sensitivity and specificity for cancer compared to controls. Studies of biomechanical and neuromuscular control of walking on uneven terrain are needed to quantify mobility limitations in adults post-stroke. Most patients require more than one agent to achieve blood pressure (BP) control, and adding a second agent is more effective than doubling the dose of existing therapy. Patients undergoing total knee replacement can have their post-operative pain equally well controlled with either intravenous or epidural analgesia. DHA was observed to decrease the uptake of MeHg in HEK293, but not in ASK cells. Cells in sparse culture were more vulnerable than those in dense. The questionnaire consisted of 60 questions about the fundamental points of the RSI. CEI containing steroid preparations demonstrated better and faster efficacy.

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Persistent impairment on spirometry in chronic eosinophilic pneumonia: A longitudinal observation study (Shizuoka-CEP study). Ultrastructural localization of calcium deposits in rat myocardium after loud noise exposure. Participants performed a semantic decision task on word pairs that included either a negative or a positive target word. Here, we show that JNK/SAPK signaling plays an important role in Wnt-dependent mammary development and malignant transformation. Advances in genomic and imaging technologies are allowing unprecedented insight into chromosome segregation in human oocytes. Treatment of Supraclinoid Internal Carotid Artery Iatrogenic Pseudoaneurym with Extracranial-to- Intracranial Bypass and Trapping: Demonstration of Technique with Video Presentation.

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The effects of acylation and phosphorylation on the formation of disulphide-linked oligomers were also studied. Deleterious mitochondrial mutations accumulate during normal human aging in postmitotic tissues. To better understand the early steps of development of paired fin buds in fish, we have analyzed the regulation of the zebrafish Sonic hedgehog gene (shh/vhh-1) in response to retinoic acid. Systemic immunological deviations toward suppression or decreased activity of the immunological response as seen in normal pregnancies, was not observed in preeclampsia, intrauterine growth retardation, intrauterine fetal death, and abruptio placentae. Four studies showed no association between WBV and LBDs, four a aygestin 5 mg bid positive association and three results were mixed depending on the exposure/outcome measure. There were no differences in anterior or posterior parenchymal measurements in either plane by fetal sex.

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Taken together, the data here provide insight into the miRNA-loading mechanisms in mammals. We recommend the use of the 3D format with MPR for patients with complex congenital cardiac disease. Lymphoscintigraphic sentinel node imaging and gamma probe detection in breast cancer with Tc-99m nanocolloidal albumin: results of an optimized protocol. Relationship between periodontal status and intellectual function among community-dwelling elderly persons. Animals will continue to play a key role in this rapidly evolving field. Treatment-related risk factors for transformation to acute myeloid leukemia and myelodysplastic syndromes in myeloproliferative neoplasms. Cyanurate mimics of hydrogen-bonding patterns of nucleic bases: crystal structure of a 1:1 molecular complex of 9-ethyladenine and N-methylcyanuric acid. The association between FCER1A gene variants and total serum IgE levels seems especially interesting and, supported by functional analyses of polymorphisms, may provide a rationale for pharmacogenetic studies on anti-IgE therapy that indirectly suppresses FcepsilonRI expression.

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Lymphocytes from tumor-bearing animals have been shown to lack antitumor function. Overall performance evaluation indicated that the kit has a rapid, high sensitivity and on-spot method for detecting P. The concentration of nutritionally important minerals in circulation is under tight homeostatic control, however, physical activity and aging influence their body stores and nutritional requirement. Comparison of the toxic effects of two duncecap larkspur (Delphinium occidentale) chemotypes in mice and cattle. Regiospecific expression of cytochrome P4501A1 and 1B1 in human uterine tissue. Changes in ocular parameters depending on the motion-in-depth of a three-dimensional display. The fractional volume of secondary osteons was not found to change significantly with age, while the fractional volume of osteon fragments significantly increases.

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Karyotypic analysis of the cotton boll weevil, Anthonomus grandis Boheman. We have aimed to analyze our outcomes in order to know the factors associated with anatomical and functional failure in POP surgery. However, striosome-matrix compartments were not evident inside the grafts. Sitagliptin or exenatide once weekly for type 2 diabetes: comparison of the clinical trials. W23 shares a 3.6 Mb core genome with the intensively studied model organism B. To examine the frequency of symptoms associated with primary angle closure in an East Asian population with high rates of disease. vulnificus were selected and divided into five groups according to their specificities to different V. In a number of Ad12-transformed hamster cell lines or in cell lines carrying foreign DNA, we have located the inserted Ad12 DNA copies on hamster chromosomes by fluorescent in situ hybridization (FISH). Describing such intrinsic structure is important to understand the transition between free and bound state, leading to supramolecular complexes with physiological interactors. Venous thromboembolism in body contouring: an analysis of 17,774 patients from the National Surgical Quality Improvement databases.

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Interactions of OCTs with antiretroviral drugs and evidence for clinical relevance are discussed. That the alignment for a highly consistent CoMFA is based on an automated 3D pharmacophore analysis has important methodological implications. The case of double primary lung adenocarcinomas with an EGFR mutation and ALK translocation successfully treated with alectinib at the post-surgical recurrence. However, molecular studies that define the diversity and abundance of microbes invading the amniotic cavity, and evaluate their clinical significance within a causal framework, are lacking. Case-control study of 12 patients with migraine without aura and 12 matched healthy control subjects. Previous anatomic studies in comparing the length of both routes applied different methods and yielded inconsistent results.

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It is an oxygenated cholesterol derivative (oxysterol), commonly present in oxidized low-density lipoprotein (LDL). The perception and knowledge of cardiovascular risk factors among medical students. The surface topography of the digenetic trematode Corrigia vitta is described by scanning electron microscope. AECs were obtained from asthmatic patients and healthy subjects and treated with anti-IL-33 after rhinovirus infection. The primary outcome measure was pain relief of at least 6 months. We investigated the effects of two neuromodulators, acetylcholine and norepinephrine, on corticothalamic responses in vitro and in vivo. Moreover, the presumed novel enzymatic activities, especially those related to diverse nuclease activities, are believed to play an important role in various biological activities of RIPs. The results of the study will be submitted for publication in peer-reviewed journals and presented at national and international scientific meetings. Changing profile of work force can give rise different types of injuries. Residues in the 11 A channel of histone deacetylase 1 promote catalytic activity: implications for designing isoform-selective histone deacetylase inhibitors.

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