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Actos (Pioglitazone)
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Actos

Actos is a moderately priced drug used to treat type 2 diabetes. It is more popular than comparable drugs. It is available in generic and brand versions. Actos is covered by most Medicare and insurance plans, but some pharmacy coupons or cash prices may be lower.

Other names for this medication:
Adride, Diaglit, Diazero, Euglim, Geoglit, Glimiprime, Glimitab, Glitter, Gluconorm, Glucut, Glycinova, Glyree, Mepride, Metanorm, Metme, Pioglar, Pioglu, Piokap, Piolem, Piomeri, Pionorm, Piosys, Piozone, Triexer, Triopil, Tripride, Ziglim, Zorep

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Also known as: Pioglitazone

Description

Actos is a medication that’s used to treat type 2 diabetes. This is a condition in which where your body has a high level of glucose (sugar) in your blood. Your pancreas normally makes a hormone called insulin, which takes glucose out of your blood and helps you use the sugar as a source of energy. With type 2 diabetes, your pancreas may not be making enough insulin to remove the sugar from your blood.

And if you have type 2 diabetes, your cells may also become insulin resistant. This means that your body makes insulin but isn’t responding to it by removing the sugar from your blood. So people with type 2 diabetes have high blood sugar levels.

What Actos does

Actos works by making your cells more sensitive to insulin. The goal is for your cells to take the glucose in your blood and use it more effectively as an energy source. Because you’re using your glucose more effectively, your blood glucose levels will decrease.

This lowers your risk of serious complications of type 2 diabetes, including heart disease, nerve damage such as neuropathy, and kidney failure.

How long does it take to work?

After you start using Actos, it may take 7 days or longer before you notice any changes in your blood glucose level. It’s important to keep taking Actos every day so that it can have the best chance to work in your body.

Dosage

Usual Adult Dose for Diabetes Type 2:

-Patients without congestive heart failure: Initial dose: 15 mg or 30 mg orally once a day -Patients with congestive heart failure (New York Heart Association [NYHA] Class I or II): Initial dose: 15 mg orally once a day Maintenance dose: 15 mg to 45 mg orally once a day based on glycemic response as determined by HbA1c Maximum dose: 45 mg orally once a day Comments: -This drug exerts its antihyperglycemic effect only in the presence of endogenous insulin and therefore is not expected to be effective in patients with type 1 diabetes mellitus or diabetic ketoacidosis. -Patients concomitantly receiving an insulin secretagogue or insulin may need to reduce the dose of the insulin secretagogue or insulin if hypoglycemia occurs. Use: As an adjunct to diet and exercise to improve glycemic control in adults with type 2 diabetes mellitus in multiple clinical settings

Detailed Actos dosage information

Overdose

If an overdose occurs and you are not feeling well, you should seek emergency medical attention or contact your health care provider immediately. You can experience the following symptoms of Actos overdose: signs of low blood sugar, such as extreme weakness, blurred vision, sweating, trouble speaking, tremors, stomach pain, confusion, and seizure (convulsions).

Storage

Store at room temperature between 15 and 30 degrees C (59 and 86 degrees F) and away from excess moisture and heat. Throw away any unused medicine after the expiration date. Keep out of the reach of children.

Side effects

The most common side effects associated with Actos are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.

Contraindications

Do not take Actos if you are allergic to Actos ingredients. Do not take Actos if you are in a state of diabetic ketoacidosis. Actos is ineffective and possibly harmful in treatment of type 1 diabetes. Do not take Actos if you have congestive heart failure or heart disease, fluid retention, a history of bladder cancer, heart attack, stroke, liver disease, certain eye problems (macular edema), or polycystic ovary syndrome. Actos is not to be used in people with blood in their urine when the cause of this is unknown. Avoid drinking alcohol. It lowers blood sugar level and may interfere with your diabetes treatment. Be careful with Actos if you are pregnant, planning to become pregnant, or breastfeeding. Do not use Actos in treatment of children under 18 years old. Actos may increase the risk of bone fracture in women (usually in the upper arm, hand, or foot). Actos can cause changes in the menstrual cycle (promote ovulation) and increase the risk of becoming pregnant. Do not take Actos for longer than recommended. Taking Actos for more than 1 year may increase your risk of developing bladder cancer.

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